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Abnormal LFT's

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Elmuhtady Said FRCP FEBGH
Elmuhtady Said FRCP FEBGH

causes and interpreitations of abnormal liver function tests

Gesundheit & Medizin
1 von 39
Abnormal LFT’s Dr E M Said
why do we check LFT’s? ,[object Object],[object Object],[object Object],[object Object]
What are LFT’s? ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Remember
. ,[object Object],[object Object],[object Object]
approach ,[object Object],[object Object]
approach ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
approach ,[object Object],[object Object],[object Object],[object Object]
approach ,[object Object],[object Object],[object Object],[object Object]
approach ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LFT profile : ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Patterns of abnormal LFT’s ,[object Object],[object Object],[object Object],[object Object]
Bilirubin ,[object Object],[object Object],[object Object],[object Object]
 
ALT ,[object Object],[object Object],[object Object],[object Object]
Typical ALT Values in Disease
 
ALP ,[object Object],[object Object],[object Object],[object Object]
 
 
Gamma GT ,[object Object],[object Object],[object Object],[object Object]
Gamma GT ,[object Object],[object Object],[object Object],[object Object],Twofold elevation with AST:ALT ratio2:1suggest alcohol abuse
 
Albumin ,[object Object],[object Object],[object Object]
Prothrombin time ,[object Object],[object Object],[object Object]
Predominantly Hepatocellular ,[object Object],[object Object]
Predominantly Hepatocellular ,[object Object],[object Object],[object Object],[object Object]
Predominantly Hepatocellular ,[object Object],[object Object],[object Object]
Predominantly Hepatocellular ,[object Object],[object Object],[object Object],Aminotransferase>500 ALT greater or equal AST
Predominantly Hepatocellular ,[object Object],[object Object],[object Object],[object Object],[object Object]
Predominantly Hepatocellular ,[object Object],[object Object],[object Object],[object Object],[object Object],exceeding1000IU/L Or 50x upper limit of normal
Predominantly Hepatocellular ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Copyright ©2003 BMJ Publishing Group Ltd. Limdi, J K et al. Postgrad Med J 2003;79:307-312 Suggested algorithm for evaluating raised transaminases
Predominantly cholestatic ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
extrahepatic cholestasis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
intrahepatic cholestasis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Copyright ©2003 BMJ Publishing Group Ltd. Limdi, J K et al. Postgrad Med J 2003;79:307-312 Suggested algorithm for evaluating a raised ALP
The role of liver biopsy ,[object Object],[object Object],[object Object]
 

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