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Professor Dr Hamed Attia
Prof. of veterinary internal medicine
Zagazig University-Egypt
Email:hamedattia0@gmail.com
Mobil No :00966547209365
Main Lines of treatment
of diseases
in farm animals
4dS To Success in Treatment
Correct
Diagnosis
Drug Used
Dose
&
Route
Duration
Main Line of Treatment
Hyagenic Medical Supportive T
11--Main Lines of treatmentMain Lines of treatment
of enteritisof enteritis
1-Anti-acid (systemic).
2-Fluid therapy.
3-Anti-inflammatory
4-Antibiotic
5-Antiparastic drugs
6-Intestinal astringent
and coating
Clinical signs of diarrhea
Calves are weak ,depressed ,anorexic
Affected animals either recovered or die
After five days.
In Calf Scour
Look on the animal
not on the feces
1-
Appetite
2-
Temperature
3-
General condition
•Standing position
•Recumbent
4-
Dehydration
Important Notes
Metabolic effects of calf scourMetabolic effects of calf scour
Dehydration
Acidosis
Electrolyte imbalance
11--Anti-acid (systemicAnti-acid (systemic(.(.
• R/Na bicarbonate 1.3% 0.5-1 L I/V
according to the degree of acedemia
Oral Fluid Therapy
I/V Fluid Therapy
33--Non steriodal anti-inflammatoryNon steriodal anti-inflammatory
• R/ Dicloprima 5%
• Dose:
• 2 Ml/ 100Kg B.W
N B:
Non Steroidal anti-inflammatory should be given after
hydration of the calf
Anti-inflammatory
Strong analgesic
Atipyretic
Anti-endotoxic
Advantages
 Antibiotice more effective on E
coli & Salmonelle
 Nuflor
 Marbocele
 Cefotaxim
 Borgal(Sulfa &Trimethoprime)
4-Broad spectrum antibiotic
66--AntiparasiticAntiparasitic agentsagents
------
• R/ Ivermectine 1cc /50 Kg. B.w.
S/C
General line for treatment ofGeneral line for treatment of
AcidosisAcidosis
• 1-Evacuation of rumen content:
•
• By using 3 liter Paraffin oil by stomach tube
• 2-Antiacid
• (a) Local: 500 g sodium bicarbonate
• &
• (b)Systemic: 2 liter isotonic sodium bicarbonate 1.3% I/V
• 3-Fluid therapy:
• Nacl 0.9% 4-6 liter I/V
•
• According to degree of dehydration
• 4-Antihistaminic:
• R/Antistamine 30-40 Ml I/V
General line for treatment ofGeneral line for treatment of
AcidosisAcidosis
• 5-Antinflamatory
• 6-Antibiotic
• Orally (procaine penicillin 10million IU
orally)
• &
• Systemic
• 7-Ruminal tonic stomachic
• -Bykahepar -genabell
• -Hepanol -propylene glycol
General line for treatment ofGeneral line for treatment of
simple indigestionsimple indigestion
• 1-Antiacid
• 0.5 kg sodium bicarbonate/orally
• 2-Ruminal tonic stomachic
• -Bykahebar
-Genabel
• 3-Purgative
• 0.5 kg orally of Mg oxide
• OR
• 2 liter of Paraffin oil
• 4-Massage of rumen from left flank
• 5-Rectal enema, back racking &exercise
General line for treatment ofGeneral line for treatment of
MasititisMasititis
• 1-AntiBiotic
• Systemic: Gentamycin,
Cefotaxim Snylox-Pentomycin
• Pentomycin
• 2-Antinflammatory
• 3 days Non steroidal AI
• 3-Antihistaminic
• 1st day
• 4-Oxytocin
• 5-Vitamin AD3E&C
General line of treatment ofGeneral line of treatment of
pneumoniapneumonia
• Broad spectrum antibiotic
• Ant inflammatory
• Bronchodilator
• Mucolytics & Expectorants
• Antihistaminic
Antibiotic used in pneumoniaAntibiotic used in pneumonia
1. 1-In less sever cases:
1-Oxytetracycline drugs
2-Enerofloxacine
IN sever cases (Shipping fever):
 Flurphenicol
 Cephalosporion .
 Sulfa &Trimethoprime
 Marboflxacine
Metabolic DiseasesMetabolic Diseases
TherapyTherapy
General line for treatmentGeneral line for treatment
of milk feverof milk fever
• 1)Source of Calcium
A-Small cow(300-
400 Kg):
R/500 ml (375 ml IV
very slowly and
125 ml SC after 30
min. at different
sites.
• Large cow( More
than 500 Kg B .w.)
• 1 Liter:
• ½ Liter at morning
• ½ Liter at evening
Examples of Ca preparationExamples of Ca preparation
• R/Ca boro-gluconate (20% or 25%)
• Or
R/ Cal. D. Mg (Ca & Dextrose & Mg)
R/Calcium amino-plex (Ca & amino acids).
NB:
• I/v Ca solution should be slowly to
prevent cardiac arrest.
• Continue for 3-5 days days or till complete
recovery
(2) Compounds which increasing calcium
level in blood:
R/ AD3E&C (15 ml / daily IM).
& R/ACTH 400-500 IU I/M
3) Anti-inflammatory (Non Steroidal)
R/Declo-phenac Na 2.5% 4 ml/100 Kg B W.
(4) Supportive treatment:
R/Dextrose 25% or 40% 2 liter IV.
Medical General lines for
treatment of hypo-phosphatemia
Source of ph Hematincs Saline
1-Source of ph
I/V&I/M S/C Orally
2-Hematinics
A-Blood transfusion
(In sever cases) Iron & VitB12.
))11((Sources of phosphorusSources of phosphorus
• A) IV slowly administration
of 60 of sodium acid
phosphate in 300 ml of
distilled water on the first
day .
• Followed by further SC
injections of similar doses at
12-hours intervals till
recovery.
• Similar daily doses (60 g) by
mouth
NB:
Treatment should be continued till 3-5 days
after disappearance of red urine (complete recoverty).
• B) patent phosphorus preparation
as:
• R/ Tonophosphan (Ph 10%)
• R/ 50ml( 25 ml IV daily&25 ml I/M till
recovery).
• C) Oral dosing with bone meal (120 g)
twice daily or dicalcium phosphate
daily for 5 days till recovery.
• Or:
• Superphos Sachets 3
• One sachet daily (oral route)
• (2) Hematinic preparation:
• (A) in sever cases:
• Blood transfusion 3-4 L of whole blood to a
450 kg cow is indicated in severe cases.
• Additional transfusion is necessary if cow is
still weak and mucous membranes are pale.
• (B) In less sever cases:
• iron, copper, cobalt, vitamin B12. (4)
R/Antoplex 15 ml I/M
• (3) Supportive therapy:
• (Glucose 25%) to treat ketosis &
hypoglycemia.
• (4)Kidney wash:
• (Glucose 5% or saline(0.9%NaCl ( to
minimize the danger of hemoglobinuric
nephritis.
3- General Lines Of
Treatment of Ketosis
1-Dextrose 25%
2-Propylene glycol
3-Dexamethasone
Make Glucose
Decreased Production
(less glucose
demand)
Increased Appetite
4-Insuline
Facilitate transport glucose
into the cell
Medical treatmentMedical treatment
• 1-Sources of glucose:
• IV injection of dextrose 25-40%
500ml for cattle (in ewes 150-
250 ml) IV, twice daily for 3-5
successive days causing
temporary hyperglycemia.
• Oral hyperglycemic
agents: propylene glycol .05
Liter orally
• Or:
• Glycerol or glycerin 0.25 Liter or
sodium propionate (100-200 gm )
once daily for 3 day).
R/Primaton :
.025 L orally
• They are glucogenic and thus
produce glucose.
Primaton
2-Hormonal therapy:
A-Glucocorticoids:
 Such as dexamethazone 10 ml (30
mg) I/M one or two doses for cattle
to increase the blood sugar level &
reduces ketone bodies formation by
utilization of acetyl coenzyme A.
Line of treatment of blood parasitesLine of treatment of blood parasites
• Fever (40-41C)
• Red Urine
• Partial loss of appetite
• Jaundice
1-Babesiosis
I- TreatmentI- Treatment::
• Important Notes:
• Treatment should be tried early before the
animal becomes anemic
· Care must also be taken to avoid complete
sterilization of the blood before sufficient
antibody is produced to provide a durable
immunity.
Drugs usedDrugs used
1- Diminazen aceturate (Batrinil-Berinil)
· Aqueous solution7% (1.05gm vial dissolved in
12.5 ml water).
· Dose 1ml/20kg ·
2-Imidocarb dipropionate (Imisol)
2ml/100Kg B W.
Symptomatic treatmentSymptomatic treatment
• Non steroidal ant inflammatory
• R/ Decloflam (1CC/25kg I/M)
• -Blood transfusion:-
• - In Sever cases 1Liter/100 Kg B W.
• General hematinics.
• R/Antoplex 15mlI/M
• Or Iron 100 1 ml /100Kg B W.
Line of treatment of blood parasitesLine of treatment of blood parasites
• Fever (40-41C)
• Corneal opacity
• Partial loss of appetite
• Enlarged pre-scapular
L.N
2-Theleriasis
Corneal opacity
TreatmentTreatment
 R/butalex injection
1CC /20 Kg I/M
Or:
Oxytetracycline L.A(5 Doses)
+ Arsinal for 5 days
Line of treatment
Of
urinary tract affections
Anti-
inflammatory
Urinary
Antiseptic
Antibiotic
Types of Antibiotic
Peniclline
&
streptomycine
Sulpha
&
Trimethprime
Cephalosporine
Gentamycine
Types of Antibiotic
According to species
Rumminant
Cephalosporine
penicillines
Equines
ulpha & Trimethoprime
Duration
of
Antibiotic
Chronic pyogenic
2-4weeks
Chronic
7-10D
Acute
3-5days
2-Urinary
Antiseptic
Urinary lavage
IV glucose
Systemic
Coli-urinal
Hexamin
Local
use of
catheters
3-Anti-inflammatory
Ketoprofen
FinadyineDecloprema
Causes Antibiotic FailureCauses Antibiotic Failure
• 1-Exposure to strong sunlight
• 2-Too-much-water
• 3-Frequency-of-dose ( daily treatment
but we decided to just double the dose
and give it every other day).
• 4-Duration is not enough.
• 5-The causative agent is virus not bacteria
• 6-The drug is not specific against the
pathogen
• 7-Contaminated needle back into the bottle.
Bacterial
vaccines
Viral
vaccines
2. Covexin* 8& 10
3 Ultrabac® 8
Mixed
vaccines
1. PNEUMO 3
2. PNEUMO 4
1. Pneumo - Bac 1. Entero – 3
Vaccine
3. Cattle Master4
4. Vira Shield 5
2. Scour Guard 3
3-Rotvec vaccine
E Coli + Rota & Corana Virus
4-Coli immune-oral
5-Nasal Gene
VACCINE FAILURESVACCINE FAILURES
• NO RESPONSE :
• Efficacy- expire Date
• stress
• Malnutrition
• Improper Dose .
• Improper Route.

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Main lines of treatmentin diseased animals proff. dr hamed attia

  • 1. Professor Dr Hamed Attia Prof. of veterinary internal medicine Zagazig University-Egypt Email:hamedattia0@gmail.com Mobil No :00966547209365 Main Lines of treatment of diseases in farm animals
  • 2. 4dS To Success in Treatment Correct Diagnosis Drug Used Dose & Route Duration
  • 3. Main Line of Treatment Hyagenic Medical Supportive T
  • 4. 11--Main Lines of treatmentMain Lines of treatment of enteritisof enteritis 1-Anti-acid (systemic). 2-Fluid therapy. 3-Anti-inflammatory 4-Antibiotic 5-Antiparastic drugs 6-Intestinal astringent and coating Clinical signs of diarrhea Calves are weak ,depressed ,anorexic Affected animals either recovered or die After five days.
  • 5. In Calf Scour Look on the animal not on the feces 1- Appetite 2- Temperature 3- General condition •Standing position •Recumbent 4- Dehydration Important Notes
  • 6. Metabolic effects of calf scourMetabolic effects of calf scour Dehydration Acidosis Electrolyte imbalance
  • 7. 11--Anti-acid (systemicAnti-acid (systemic(.(. • R/Na bicarbonate 1.3% 0.5-1 L I/V according to the degree of acedemia
  • 8. Oral Fluid Therapy I/V Fluid Therapy
  • 9. 33--Non steriodal anti-inflammatoryNon steriodal anti-inflammatory • R/ Dicloprima 5% • Dose: • 2 Ml/ 100Kg B.W N B: Non Steroidal anti-inflammatory should be given after hydration of the calf Anti-inflammatory Strong analgesic Atipyretic Anti-endotoxic Advantages
  • 10.  Antibiotice more effective on E coli & Salmonelle  Nuflor  Marbocele  Cefotaxim  Borgal(Sulfa &Trimethoprime) 4-Broad spectrum antibiotic
  • 12. General line for treatment ofGeneral line for treatment of AcidosisAcidosis • 1-Evacuation of rumen content: • • By using 3 liter Paraffin oil by stomach tube • 2-Antiacid • (a) Local: 500 g sodium bicarbonate • & • (b)Systemic: 2 liter isotonic sodium bicarbonate 1.3% I/V • 3-Fluid therapy: • Nacl 0.9% 4-6 liter I/V • • According to degree of dehydration • 4-Antihistaminic: • R/Antistamine 30-40 Ml I/V
  • 13. General line for treatment ofGeneral line for treatment of AcidosisAcidosis • 5-Antinflamatory • 6-Antibiotic • Orally (procaine penicillin 10million IU orally) • & • Systemic • 7-Ruminal tonic stomachic • -Bykahepar -genabell • -Hepanol -propylene glycol
  • 14. General line for treatment ofGeneral line for treatment of simple indigestionsimple indigestion • 1-Antiacid • 0.5 kg sodium bicarbonate/orally • 2-Ruminal tonic stomachic • -Bykahebar -Genabel • 3-Purgative • 0.5 kg orally of Mg oxide • OR • 2 liter of Paraffin oil • 4-Massage of rumen from left flank • 5-Rectal enema, back racking &exercise
  • 15. General line for treatment ofGeneral line for treatment of MasititisMasititis • 1-AntiBiotic • Systemic: Gentamycin, Cefotaxim Snylox-Pentomycin • Pentomycin • 2-Antinflammatory • 3 days Non steroidal AI • 3-Antihistaminic • 1st day • 4-Oxytocin • 5-Vitamin AD3E&C
  • 16. General line of treatment ofGeneral line of treatment of pneumoniapneumonia • Broad spectrum antibiotic • Ant inflammatory • Bronchodilator • Mucolytics & Expectorants • Antihistaminic
  • 17. Antibiotic used in pneumoniaAntibiotic used in pneumonia 1. 1-In less sever cases: 1-Oxytetracycline drugs 2-Enerofloxacine IN sever cases (Shipping fever):  Flurphenicol  Cephalosporion .  Sulfa &Trimethoprime  Marboflxacine
  • 19. General line for treatmentGeneral line for treatment of milk feverof milk fever • 1)Source of Calcium A-Small cow(300- 400 Kg): R/500 ml (375 ml IV very slowly and 125 ml SC after 30 min. at different sites.
  • 20. • Large cow( More than 500 Kg B .w.) • 1 Liter: • ½ Liter at morning • ½ Liter at evening
  • 21. Examples of Ca preparationExamples of Ca preparation • R/Ca boro-gluconate (20% or 25%) • Or R/ Cal. D. Mg (Ca & Dextrose & Mg) R/Calcium amino-plex (Ca & amino acids). NB: • I/v Ca solution should be slowly to prevent cardiac arrest. • Continue for 3-5 days days or till complete recovery
  • 22. (2) Compounds which increasing calcium level in blood: R/ AD3E&C (15 ml / daily IM). & R/ACTH 400-500 IU I/M 3) Anti-inflammatory (Non Steroidal) R/Declo-phenac Na 2.5% 4 ml/100 Kg B W. (4) Supportive treatment: R/Dextrose 25% or 40% 2 liter IV.
  • 23. Medical General lines for treatment of hypo-phosphatemia Source of ph Hematincs Saline
  • 26. ))11((Sources of phosphorusSources of phosphorus • A) IV slowly administration of 60 of sodium acid phosphate in 300 ml of distilled water on the first day . • Followed by further SC injections of similar doses at 12-hours intervals till recovery. • Similar daily doses (60 g) by mouth NB: Treatment should be continued till 3-5 days after disappearance of red urine (complete recoverty).
  • 27. • B) patent phosphorus preparation as: • R/ Tonophosphan (Ph 10%) • R/ 50ml( 25 ml IV daily&25 ml I/M till recovery).
  • 28. • C) Oral dosing with bone meal (120 g) twice daily or dicalcium phosphate daily for 5 days till recovery. • Or: • Superphos Sachets 3 • One sachet daily (oral route)
  • 29. • (2) Hematinic preparation: • (A) in sever cases: • Blood transfusion 3-4 L of whole blood to a 450 kg cow is indicated in severe cases. • Additional transfusion is necessary if cow is still weak and mucous membranes are pale. • (B) In less sever cases: • iron, copper, cobalt, vitamin B12. (4) R/Antoplex 15 ml I/M
  • 30. • (3) Supportive therapy: • (Glucose 25%) to treat ketosis & hypoglycemia. • (4)Kidney wash: • (Glucose 5% or saline(0.9%NaCl ( to minimize the danger of hemoglobinuric nephritis.
  • 31. 3- General Lines Of Treatment of Ketosis 1-Dextrose 25% 2-Propylene glycol 3-Dexamethasone Make Glucose Decreased Production (less glucose demand) Increased Appetite 4-Insuline Facilitate transport glucose into the cell
  • 32. Medical treatmentMedical treatment • 1-Sources of glucose: • IV injection of dextrose 25-40% 500ml for cattle (in ewes 150- 250 ml) IV, twice daily for 3-5 successive days causing temporary hyperglycemia.
  • 33. • Oral hyperglycemic agents: propylene glycol .05 Liter orally • Or: • Glycerol or glycerin 0.25 Liter or sodium propionate (100-200 gm ) once daily for 3 day). R/Primaton : .025 L orally • They are glucogenic and thus produce glucose. Primaton
  • 34. 2-Hormonal therapy: A-Glucocorticoids:  Such as dexamethazone 10 ml (30 mg) I/M one or two doses for cattle to increase the blood sugar level & reduces ketone bodies formation by utilization of acetyl coenzyme A.
  • 35. Line of treatment of blood parasitesLine of treatment of blood parasites • Fever (40-41C) • Red Urine • Partial loss of appetite • Jaundice 1-Babesiosis
  • 36. I- TreatmentI- Treatment:: • Important Notes: • Treatment should be tried early before the animal becomes anemic · Care must also be taken to avoid complete sterilization of the blood before sufficient antibody is produced to provide a durable immunity.
  • 37. Drugs usedDrugs used 1- Diminazen aceturate (Batrinil-Berinil) · Aqueous solution7% (1.05gm vial dissolved in 12.5 ml water). · Dose 1ml/20kg · 2-Imidocarb dipropionate (Imisol) 2ml/100Kg B W.
  • 38. Symptomatic treatmentSymptomatic treatment • Non steroidal ant inflammatory • R/ Decloflam (1CC/25kg I/M) • -Blood transfusion:- • - In Sever cases 1Liter/100 Kg B W. • General hematinics. • R/Antoplex 15mlI/M • Or Iron 100 1 ml /100Kg B W.
  • 39. Line of treatment of blood parasitesLine of treatment of blood parasites • Fever (40-41C) • Corneal opacity • Partial loss of appetite • Enlarged pre-scapular L.N 2-Theleriasis Corneal opacity
  • 40. TreatmentTreatment  R/butalex injection 1CC /20 Kg I/M Or: Oxytetracycline L.A(5 Doses) + Arsinal for 5 days
  • 41. Line of treatment Of urinary tract affections Anti- inflammatory Urinary Antiseptic Antibiotic
  • 43. Types of Antibiotic According to species Rumminant Cephalosporine penicillines Equines ulpha & Trimethoprime
  • 47. Causes Antibiotic FailureCauses Antibiotic Failure • 1-Exposure to strong sunlight • 2-Too-much-water • 3-Frequency-of-dose ( daily treatment but we decided to just double the dose and give it every other day). • 4-Duration is not enough.
  • 48. • 5-The causative agent is virus not bacteria • 6-The drug is not specific against the pathogen • 7-Contaminated needle back into the bottle.
  • 49. Bacterial vaccines Viral vaccines 2. Covexin* 8& 10 3 Ultrabac® 8 Mixed vaccines 1. PNEUMO 3 2. PNEUMO 4 1. Pneumo - Bac 1. Entero – 3 Vaccine 3. Cattle Master4 4. Vira Shield 5 2. Scour Guard 3 3-Rotvec vaccine E Coli + Rota & Corana Virus 4-Coli immune-oral 5-Nasal Gene
  • 50. VACCINE FAILURESVACCINE FAILURES • NO RESPONSE : • Efficacy- expire Date • stress • Malnutrition • Improper Dose . • Improper Route.