1. GLOBAL CLIMATE CHANGE

2. Topics of Global Climate Change: Atmospheric Composition & Air Pollution Behavioral, Social, & Economic Dimensions Climate Variability & Change Coastal & Ocean Studies Ecosystems, Biodiversity, & Biogeochemistry Energy Resources & Use Environmental Technology & Transportation Global Carbon Cycle Global Water Cycle & Water Resources Human Health International Politics/Activities Land Use, Land Cover Change, & Agriculture Observations, Modeling, & Data Systems Sustainable Development

3. Steven Cowley The promise of fusion seems to have inspired more science-fiction novels than it has real developments in renewable energy, but Steven Cowley has begun to upset that balance. As director of the Culham Fusion Science Center, he's collaborating with the UK Atomic Energy Authority and researchers on the France-based ITER fusion device on projects that may lead to cheap, nearly limitless carbon-free energy.Fusion (the process by which lightweight atoms under pressure are fused to form heavier atoms, releasing energy) has long been the Holy Grail of renewable energy, but at the moment it only occurs in the cores of stars. Yet Cowley isn't too shy to proclaim that harnessing its power on an Earthly scale is now inevitable. At UCLA, he made observations on some of the most violent phenomena in the local universe -- solar flares, storms in the Earth's magnetosphere -- and now his research is coming directly into play as he plans devices that, theoretically, would contain 100-million-degree gas using powerful magnetic fields.

4. AnupamMishra AnupamMishra travels across water-challenged India studying rainwater harvesting methods and learning from the people behind them. He presents his findings to NGOs, development agencies and environmental groups, pulling from centuries of indigenous wisdom that has found water for drinking and irrigation even in extremely arid landscapes through wells, filter ponds and other catchment systems. A founding member of the Gandhi Peace Foundation, Mishra is working to bridge the gap between modern water management technology and india's heritage of water harvesting, so that every community is self-sustainable and efficiently safekeeping an increasingly scarce and precious resource.

5. Gordon Brown UK Prime Minister Gordon Brown is one of the world's most experienced political leaders, with a deep understanding of the global economy based on 10 years' experience as Great Britain's Chancellor of the Exchequer. He has been a key architect of the G8's agreements on poverty and climate change, and has provided a passionate voice to encourage the developed world to aid struggling African countries. He is an advocate of global solutions for global problems -- through both the reinvention of international institution and the advancement of a global ethics.Mr. Brown has promoted technology as a tool for economic (and environmental) recovery. With his charge to "count the carbon and the pennies," research on electric cars and residential energy efficiency are slated to become a major part of the UK's recovery plan. He has pushed for universal broadband and a general increase in spending on science. He has also sought to use new communication tools like Twitter and YouTube as a means to communicate government policy.

6. Rob Hopkins Rob Hopkins leads a vibrant new movement of towns and cities that utilize local cooperation and interdependence to shrink their ecological footprints. In the face of climate change he developed the concept of Transition Initiatives -- communities that produce their own goods and services, curb the need for transportation and take other measures to prepare for a post-oil future. While Transition shares certain principles with greenness and sustainability, it is a deeper vision concerned with re-imagining our future in a self-sufficient way and building resiliency. Transforming theory to action, Hopkins is also the co-founder and a resident of the first Transition Initiative in the UK, in Totnes, Devon. As he refuses to fly, it is from his home in Totnes that he offers help to hundreds of similar communities that have sprung up around the world, in part through his blog, transitionculture.orgHopkins, who's trained in ecological design, wrote the principal work on the subject, Transition Handbook: From Oil Dependency to Local Resilience, a 12-step manual for a postcarbon future.

7. Magnus Larsson Architecture student Magnus Larsson wants to turn some of the most deserted and harsh landscapes on the planet into habitable structures. How? By turning loose sand dunes into solid architecture using bacteria. A team at UC Davis has been looking at the microorganism bacillus pasteurii to solidify the ground in earthquake-prone areas. As Larsson puts it, "All I did was to deliberately misapply their technology ... and to pump up the scale, and turn it into a 6,000-km-long wall that's made of sand and protects against sand."After talking with Jason DeJong at UC Davis and with Stefano Ciurli, a b. pasteurii expert at the University of Bologna, Larsson put together a team at University College London to grow the bacteria and attempt to solidify sand. His Holcim Award-winning proposal is a complement to the Green Wall Sahara shelterbelt, being planted across the African continent. Larsson is now investigating how to bring the project to the next stage: a 1:1 scale prototype.

8. Mathieu Lehanneur Mathieu Lehanneur first began turning the heads of design junkies at MOMA's 2008 show "Design and the Elastic Mind"-- a watershed survey celebrating fusions of technology and wild imagination. With its Lucite lines, lush green interior and rounded corners, the Andrea purifier featured in the exhibit resembles a mash-up of a terrarium and an iMac, but its function is less visible. Inspired by NASA research and designed by Lehanneur and partner David Edwards so that the plants in it metabolize the micro-toxins in the air, it's nothing less than a domestic breathing machine. Though he's inspired by nature, Lehanneur isn't interested in biomimicry, but rather in the symbiosis between living and synthetic materials, often to solve environmental problems. Lehanneur's Local River, at first glance a large aquarium-cum-herb garden, is in fact designed to be an indoor food farm, with the locavore in mind.

9. Rachel Armstrong Rachel Armstrong is a medical doctor, multi-media producer, science fiction author and arts collaborator. Her current research explores architectural design and mythologies about new technology. She is working with scientists and architects to explore cutting-edge, sustainable technologies. Armstrong's hope is that, in the future, cities will be able to replace the energy they draw from the environment, respond to the needs of their populations and eventually become regarded as "alive" -- in the same way we think about parks or gardens. Since "metabolic materials" are made from terrestrial chemistry, they would not be exclusive to the developed world, and would have the potential to transform urban environments worldwide.

10. James Balog To see the natural world through James Balog's lens is to see it as an artist would -- through fresh eyes, as if for the first time, with no preconceived notions. His photos of jungle animals, for instance, are arresting in their directness, simplicity, even sensuality. His subjects assume the same weight and importance as a human portrait sitter, and demand (as a human subject would) that the viewer engage with them rather than simply spectate. His newest work is no less powerful, no less engaging -- and it carries an urgent message. For several years, Balog has been going up north to shoot the half-alive ice of the mammoth glaciers for his Extreme Ice Survey, a look at the shocking effects of abrupt climate change in Alaska, Greenland and Iceland. Soaring, dripping, glowing and crumbling, arctic ice under Balog's eye requires the viewer to engage. A new Nova/PBS TV special and a new book, Extreme Ice Now, are helping him spread the word that this glorious world is degrading at a speed we couldn't imagine until we saw it through his eyes.

11. Cary Fowler Tucked away under the snows of the Arctic Circle is the Svalbard Global Seed Vault. Sometimes called the doomsday vault, it's nothing less than a backup of the world's biological diversity in a horticultural world fast becoming homogenous in the wake of a flood of genetically identical GMOs. For Cary Fowler, a self-described Tennessee farm boy, this vault is the fulfillment of a long fight against shortsighted governments, big business and potential disaster. Inside the seed vault, Fowler and his team work on preserving wheat, rice and hundreds of other crops that have nurtured humanity since our ancestors began tending crops -- and ensuring that the world's food supply has the diversity needed to stand against the omnipresent threats of disease, climate change and famine.

12. Stewart Brand Founder of the Whole Earth Catalog, cofounder of the Well and the Long Now Foundation, writer, editor and game designer, Stewart Brand has helped to define the collaborative, data-sharing, forward-thinking world we live in now. Since the 1960s, he has maintained that — given access to the information we need — humanity can make the world a better place. One of his early accomplishments: helping to persuade NASA to release the first photo of the Earth from space. The iconic Big Blue Marble became the cover for his Whole Earth Catalog, a massive compendium of resources and facts he thought people might like to know. And we did: the 1972 edition sold 1.5 million copies. In 1987, he wrote The Media Lab: Inventing the Future at MIT; in 1994, How Buildings Learn.Currently Brand is working with computer scientist Danny Hillis to build the Clock of the Long Now, a 10,000-year timepiece; his Long Now Foundation also runs a number of spinoff projects, including the Rosetta Project, cataloguing the world's languages, and the Long Bets website. He's also busy with the Global Business Network (part of the Monitor Group), helping businesses plan for the near and way-far future.

13. Jane Poynter Jane Poynter is one of only eight people to live in Biosphere 2 for two years. In 1991, she and seven others were locked in a three-acre, hermetically-sealed environment in the Arizona desert. Nothing was allowed in or out, and everything had to be recycled. Poynter, and the rest of the team, endured dangerously low oxygen levels and constant hunger, but they survived -- something many scientists said was impossible. Poynter went on to found Paragon Space Development Corporation, along with her former fellow biospherian and now husband, Taber MacCallum. Paragon develops technologies that might allow humans to live in extreme environments such as outer space and underwater. As president of Paragon, Poynter has had experiments flown on the International Space Station, Russian Mir Space Station and US Space Shuttle, as well as working on underwater technologies with the US Navy. She continues to consult on and write about sustainable development and new green technologies. In concert with the World Bank, she has worked on projects to mitigate climate change and to grow crops in typically arid and hostile regions of Africa and Central America.

14. Jonathan Drori Jonathan Drori has dedicated his career to media and learning. As the Head of Commissioning for BBC Online, he led the effort to create bbc.co.uk, the online face of the BBC (an effort he recalls fondly). He came to the web from the TV side of the BBC, where as an editor and producer he headed up dozens of television series on science, education and the arts. After almost two decades at the BBC, he's now a director at Changing Media Ltd., a media and education consultancy, and is a visiting professor at University of Bristol, where he studies educational media and misperceptions in science. He continues to executive produce the occasional TV series, including 2004's award-winning "The DNA Story" and 2009's "Great Sperm Race." He is on the boards of the Royal Botanic Gardens and the Woodland Trust.

15. Ray Anderson Ray Anderson is the founder of Interface, the company that makes those adorable Flor carpet tiles (as well as lots of less whizzy but equally useful flooring and fabric). He was a serious carpet guy, focused on building his company and making great products. Then he read Paul Hawken's book The Ecology of Commerce. Something clicked: with his company's global reach and manufacturing footprint, he was in a position to do something very real, very important, in building a sustainable world. Anderson focused the company's attention on sustainable decisionmaking, taking a hard look at suppliers, manufacturing processes, and the beginning-to-end life cycle of all its products. (For example: If you can't find a place to recycle a worn or damaged Flor tile, Interface invites you to send it back to them and they'll do it for you.) They call this drive Mission Zero: "our promise to eliminate any negative impact our company may have on the environment by the year 2020."

16. Shai Agassi When horrific climate-change scenarios elicit little but endless chatter from governments and entrenched special interests, the difference between talk and action represent an embarrassing gulf. Meet Shai Agassi, who has stepped fearlessly into that gap. His approach to solving the puzzle of electric automobiles could spark nothing short of an automotive revolution. Agassi stunned the software industry in 2007 by resigning from SAP to focus on his vision for breaking the world's fossil-fuel habit, a cause he had championed since his fuse was lit at a Young Global Leaders conference in 2005. Through his enthusiastic persistence, Agassi's startup Better Place has signed up some impressive partners -- including Nissan-Renault and the countries of Israel and Denmark.

17. Saul Griffith Innovator and inventor Saul Griffith has a uniquely open approach to problem solving. Whether he's devising a way to slash the cost of prescription eyeglasses or teaching science through cartoons, Griffith makes things and then shares his ideas with the world. A proponent of open-source information, he established Instructables , an open website showing how to make an array of incredible objects. He is the co-founder of numerous companies including Squid Labs, Low Cost Eyeglasses, Potenco and Makani Power, where he is President and Chief Scientist. His companies have invented a myriad of new devices and materials, such as a "smart" rope that senses its load, or a machine for making low-cost eyeglass lenses through a process inspired by a water droplet. He is a columnist at Make magazine and co-writes How Toons! He's fascinated with materials that assemble themselves, and with taking advantage of those properties to make things quickly and cheaply.

18. KamalMeattle KamalMeattle has a vision to reshape commercial building in India using principles of green architecture and sustainable upkeep (including an air-cleaning system that involves massive banks of plants instead of massive banks of HVAC equipment). He started the Paharpur Business Centre and Software Technology Incubator Park (PBC-STIP), in New Delhi, in 1990 to provide "instant office" space to technology companies. PBC-STIP's website publishes its air quality index every day, and tracks its compliance to the 10 principles of the UN Global Compact, a corporate-citizenship initiative. Meattle has long been a environmental activist in India. In the 1980s he helped India's apple industry develop less-wasteful packaging to help save acres of trees. He then began a campaign to help India's millions of scooter drivers use less oil. His next plan is to develop a larger version of PBC-STIP, making a green office accessible to more businesses in New Delhi and serving as an example of low-cost, low-energy office life.

19. Capt. Charles Moore A yachting competition across the Pacific led veteran seafarer Charles Moore to discover what some have since deemed the world's largest "landfill" -- actually a huge water-bound swath of floating plastic garbage the size of two Texases. Trapped in an enormous slow whirlpool called the Pacific Gyre, a mostly stagnant, plankton-rich seascape spun of massive competing air currents, this Great Pacific Garbage Patch in some places outweighs even the surface waters' biomass six-to-one. Moore said after his return voyage, "There were shampoo caps and soap bottles and plastic bags and fishing floats as far as I could see. Here I was in the middle of the ocean, and there was nowhere I could go to avoid the plastic." Since his discovery, Moore has been analyzing the giant litter patch and its disastrous effects on ocean life. Through the Algalita Marine Research Foundation, he hopes to raise awareness about the problem and find ways to restrict its growth. He's now leading several expeditions to sample plastic fragments across thousands of miles of the Pacific.

20. Peter Ward Paleontologist and astrobiologist Peter D. Ward studies the Cretaceous-Tertiary extinction event (the one that killed the dinosaurs) and other mass extinctions. He is a leader in the intriguing new field of astrobiology, the study of the origin, distribution and evolution of life in the universe. In his book Rare Earth he theorizes that complex life itself is so rare, it's quite possible that Earth is the only planet that has any. But, he theorizes, simple life may exist elsewhere -- and possibly be more common than we think. His upcoming book, The Medea Hypothesis, makes a bold argument that even here on Earth, life has come close to being wiped out several times. Contrary to the "Gaia hypothesis" of a self-balancing, self-perpetuating circle of life, Ward's Medea hypothesis details the scary number of times that life has come close to flatlining, whether due to comet strikes or an overabundance of bacteria. In March 2009, Ward's 8-hour television series, Animal Armageddon, premieres on Animal Planet Network.

21. JamaisCascio Unlike the scores of futurists peddling nightmare scenarios of global catastrophe and social meltdown, JamaisCascio proposes a different, often surprising alternative: What if human beings, and all of our technology, could actually manage to change things for the better? The strangely plausible worlds Cascio imagines far outstrip conventional thinking: worlds in which surveillance is universal, networks are embedded in all aspects of life, and the Web augments our very eyesight. But rather than focusing on the obvious Orwellian aspects of these looming changes, Cascio suggests that the rapid democratization of these technologies will be empowering rather than enslaving. After acting as the co-founder of WorldChanging.com, Cascio has, since 2006, made his online home at OpenTheFuture.com. Recently, he was part of Superstruct, part of the Institute for the Future's 2009 Ten-Year Forecast. He's now working on a set of 50-year scenarios that will serve as framing material for the TYF & Superstruct content. He's also at work on a book on the use of foresight as a way of dealing with periods of significant uncertainty and change.

22. Larry Burns Larry Burns is on a mission: to reinvent the automobile using nonpolluting hydrogen fuel cells. As the vice president of R&D and strategic planning at GM, he's one of the people who will be called on to lead the US auto industry into its next incarnation. Burns has been a persistent advocate of hydrogen power and other advanced propulsion and materials technologies for cars. His thinking is, the industry can keep making small energy improvements in the current cars it makes -- or it can take a big leap forward to build a whole new kind of car. "GM can't have its business growth capped by energy, safety or environmental issues. We need a transition from the internal combustion engine -- a technology that has been essentially the same for 120 years. ... We have the opportunity for an all-new automotive DNA based on electric motors and fuel cells." Larry Burns interviewed on Wired.com

23. John Francis One day in 1983, John Francis stepped out on a walk. For the next 22 years, he trekked and sailed around North and South America, carrying a message of respect for the Earth -- for 17 of those years, without speaking. During his monumental, silent trek, he earnedan MA in environmental studies and a PhD in land resources. Today his Planetwalk foundation consults on sustainable development and works with educational groups to teach kids about the environment. "Part of the mystery of walking is that the destination is inside us and we really don't know when we arrive until we arrive." John Francis

24. Paul MacCready Through his life, Paul MacCready turned his mind, energy and heart toward his two passions: flight and the Earth. His early training as a fighter and glider pilot (glider pilots still use the "MacCready speed ring" he developed after World War II) led him to explore nontraditional flight and nontraditional energy sources. In the 1970s, he and his company, AeroVironment, designed and built two record-breaking human-powered planes: the Gossamer Condor, the first human-powered aircraft to complete a one-mile course set by the Kremer Prize, and the Gossamer Albatross, the first to cross the English Channel. He then turned his wide-ranging mind toward environmentally responsible design, informed by his belief that human expansion poses a grave threat to the natural world. His team at AeroVironment prototyped an electric car that became General Motors' pioneering EV-1. They explored alternative energy sources, including building-top wind turbines. And they developed a fleet of fascinating aircraft -- including his Helios solar-powered glider, built to fly in the very top 2 percent of Earth's atmosphere, and the 2005 Global Observer, the first unmanned plane powered by hydrogen cells.

25. Norman Foster From museums and banks to airports and bridges, from apartment buildings to the Reichstag, in the past 35 years Norman Foster's beautiful and efficient designs have dramatically changed the character of cities (think of the London Gherkin) and landscapes (the Viaduc de Millau) around the world. A common philosophy connects all of them, starting with social responsiveness and the use of natural resources (ventilation, light). Some of Foster's work has sparked controversy (such as his pyramid in Astana, Kazakhstan), but he has never ignored a chance to rewrite the rules of architecture, be it by tackling audaciously huge construction projects or by designing wind turbines and partly-solar-powered electric buses.

26. Michael Pollan Few writers approach their subjects with the rigor, passion and perspective that's typical of Michael Pollan. Whereas most humans think we are Darwin's most accomplished species, Pollan convincingly argues that plants — even our own front lawns — have evolved to use us as much as we use them. The author and New York Times Magazine contributor is, as Newsweek asserts, “an uncommonly graceful explainer of natural science,” for his investigative stories about food, agriculture, and the environment. His most recent book, The Omnivore's Dilemma, was named one of the top ten nonfiction titles of 2006.As the director of the Knight Program in Science and Environmental Journalism at UC Berkeley, Pollan is cultivating the next generation of green reporters.

27. Amory Lovins Amory Lovins was worried (and writing) about energy long before global warming was making the front -- or even back -- page of newspapers. Since studying at Harvard and Oxford in the 1960s, he's written dozens of books, and initiated ambitious projects -- cofounding the influential, environment-focused Rocky Mountain Institute; prototyping the ultra-efficient Hypercar -- to focus the world's attention on alternative approaches to energy and transportation. His critical thinking has driven people around the globe -- from world leaders to the average Joe -- to think differently about energy and its role in some of our biggest problems: climate change, oil dependency, national security, economic health, and depletion of natural resources. Lovins offers solutions as well. His book and site Winning the Oil Endgame shows how all US oil use can be eliminated by 2040. Lovins has always focused on solutions that conserve natural resources while also promoting economic growth; Texas Instruments and Wal-Mart are just two of the mega-corporations he has advised on improving energy efficiency.

28. Juan Enriquez A broad thinker who studies the intersection of science, business and society, Juan Enriquez has a talent for bridging disciplines to build a coherent look ahead. Enriquez was the founding director of the Harvard Business School Life Sciences Project, and has published widely on topics from the technical (global nucleotide data flow) to the sociological (gene research and national competitiveness), and was a member of Celera Genomics founder Craig Venter's marine-based team to collect genetic data from the world's oceans. Formerly CEO of Mexico City's Urban Development Corporation and chief of staff for Mexico's secretary of state, Enriquez played a role in reforming Mexico's domestic policy and helped negotiate a cease-fire with Zapatista rebels. He is a Managing Director at Excel Medical Ventures, a life sciences venture capital firm, and the chair and CEO of Biotechonomy, a research and investment firm helping to fund new genomics firms. The Untied States of America, his latest book, looks at the forces threatening America's future as a unified country.

29. John Doerr John Doerr, a partner in famed VC firm Kleiner Perkins Caufield & Byers, made upwards of $1 billion picking dot-com stars like Amazon, Google, Compaq and Netscape. (He also picked some flops, like Go Corporation and the scandal-ridden MyCFO.com.) He was famously quoted saying, "The Internet is the greatest legal creation of wealth in history," right before the dot-com crash. But now he's back, warning that carbon-dioxide-sputtering, gas-powered capitalism will destroy us all, and that going green may be the "biggest economic opportunity of the 21st century." So Kleiner Perkins has invested $200 million in so-called greentech, a combination of startups that are pioneering alternative energy, waste remediation and other schemes to prevent the coming environmental calamity. But Doerr is afraid that it might be too little, too late.

30. Janine Benyus In the world envisioned by science author Janine Benyus, a locust's ability to avoid collision within a roiling cloud of its brethren informs the design of a crash-resistant car; a self-cleaning leaf inspires a new kind of paint, one that dries in a pattern that enables simple rainwater to wash away dirt; and organisms capable of living without water open the way for vaccines that maintain potency even without refrigeration -- a hurdle that can prevent life-saving drugs from reaching disease-torn communities. Most important, these cool tools from nature pull off their tricks while still managing to preserve the environment that sustains them, a life-or-death lesson that humankind is in need of learning. As a champion of biomimicry, Benyus has become one of the most important voices in a new wave of designers and engineers inspired by nature. Her most recent project, AskNature, explores what happens if we think of nature by function and looks at what organisms can teach us about design.

31. Alex Steffen Alex Steffen is cofounder and executive editor of WorldChanging.com. Part blog and part eco-activist street team, WorldChanging.com serves as a clearinghouse of information and inspiration dedicated to increasing sustainability and livability into the 21st century, emphasizing solutions over problems. Steffen was an environmental journalist in Seattle when he realized that the tools and methods for improving society's ecological profile by and large already exist -- they just need better PR. Steffen and friend JamaisCascio co-founded WorldChanging.com to provide that PR, linking to and posting stories by dozens of contributors around the world on everything from consumer activism and sustainable farming to alternative energy and green building projects, to technology, globalization, and human rights. World Changing, a sprawling 600-page collection of content from the website combined with new material, was published in 2006 to wide acclaim.

32. E. O. Wilson One of the world's most distinguished scientists, E.O. Wilson is a professor and honorary curator in entomology at Harvard. In 1975, he published Sociobiology: The New Synthesis,a work that described social behavior, from ants to humans. Drawing from his deep knowledge of the Earth's "little creatures" and his sense that their contribution to the planet's ecology is underappreciated, he produced what may be his most important book, The Diversity of Life. In it he describes how an intricately interconnected natural system is threatened by man's encroachment, in a crisis he calls the "sixth extinction" (the fifth one wiped out the dinosaurs). With his most recent book, The Creation, he wants to put the differences of science- and faith-based explanations aside "to protect Earth's vanishing natural habitats and species ...; in other words, the Creation, however we believe it came into existence."

33. Edward Burtynsky To describe Canadian photographer Edward Burtynsky's work in a single adjective, you have to speak French: jolie-laide. His images of scarred landscapes -- from mountains of tires to rivers of bright orange waste from a nickel mine -- are eerily pretty yet ugly at the same time. Burtynsky's large-format color photographs explore the impact of humanity's expanding footprint and the substantial ways in which we're reshaping the surface of the planet. His images powerfully alter the way we think about the world and our place in it. With his blessing and encouragement, WorldChanging.com and others use his work to inspire ongoing global conversations about sustainable living. Burtynsky's photographs are included in the collections of many major museums, including BibliotèqueNationale in Paris and the Museum of Modern Art in New York. A large-format book, 2003's Manufactured Landscapes, collected his work, and in 2007, a documentary based on his photography, also called Manufactured Landscapes, debuted at the Toronto Film Festival before going on to screen at Sundance and elsewhere. It was released on DVD in March 2007.

34. Amy Smith Mechanical engineer Amy Smith's approach to problem-solving in developing nations is refreshingly common-sense: Invent cheap, low-tech devices that use local resources, so communities can reproduce her efforts and ultimately help themselves. Smith, working with her students at MIT, has come up with several useful tools, including an incubator that stays warm without electricity, a simple grain mill, and a tool that converts farm waste into cleaner-burning charcoal. The inventions have earned Smith three prestigious prizes: the B.F. Goodrich Collegiate Inventors Award, the MIT-Lemelson Prize, and a MacArthur "genius" grant. Her course, "Design for Developing Countries," is a pioneer in bringing humanitarian design into the curriculum of major institutions. Going forward, the former Peace Corps volunteer strives to do much more, bringing her inventiveness and boundless energy to bear on some of the world's most persistent problems.

35. Ross Lovegrove Ross Lovegrove is truly a pioneer of industrial design. As founder of Studio X in the Notting Hill area of London, the Welsh-born designer has exuberantly embraced the potential offered by digital technologies. However, he blends his love of high tech with a belief that the natural world had the right idea all along: Many of his pieces are inspired by principles of evolution and microbiology. Delightedly crossing categories, Lovegrove has worked for clients as varied as Apple, Issey Miyake, Herman Miller and Airbus, and in 2005 he was awarded the World Technology Award for design. His personal artwork has been exhibited at MoMA in New York, the Pompidou Centre in Paris and the Design Museum in London. Lovegrove's astonishing objects are the result of an ongoing quest to create forms that, as he puts it, touch people's soul.

36. Cameron Sinclair After training as an architect, Cameron Sinclair (then age 24) joined Kate Stohr to found Architecture for Humanity, a nonprofit that helps architects apply their skills to humanitarian efforts. Starting with just $700 and a simple web site in 1999, AFH has grown into an international hub for humanitarian design, offering innovative solutions to housing problems in all corners of the globe. Whether rebuilding earthquake-ravaged Bam in Iran, designing a soccer field doubling as an HIV/AIDS clinic in Africa, housing refugees on the Afghan border, or helping Katrina victims rebuild, Architecture for Humanity works by Sinclair's mantra: "Design like you give a damn." (Sinclair and Stohrcowrote a book by the same name, released in 2006.)