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- 46. Medications 48 hours Sulfa Drugs 12 hours Barbituates 4 weeks Tranquilizer 30 hours Increased blood pressure Phenylpropanola-mine 30 hours Increased heart rate Anithistamine 15 hours Decongestant, stimulant Ephedrine 15 hours Pain Killer, may mask real problem Acetaminophen 2 hours Pain Killer, may mask real problem Aspirin Varies Stimulant, induces anxiety Caffeine Time To Clear Effects Chemical