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August 7, 2012   www.global-arena.com   1
Executive Summary
   Location matter to business. Framework conditions, including market, talent and
   infrastructure factors affect business decisions when it comes to R&D center site selection.
   Recent reports and the PwC Global CEO Survey 2012 show that in particular talent related
   aspects are becoming more and more critical.

   Despite a skilled labour force, high quality of life and a state of the art research Infrastructure
   Europe is hit hard by restructure plans closing or relocating pharmaceutical R&D centers in
   favour of US or Asian locations. As part of its Go-global solutions Global-Arena.com’s
   interactive analysis to the most attractive locations for pharmaceutical R&D centers location in
   Europe unveils the comparative advantages of 19 European economies: 

   •  The United Kingdom, France and Germany offer the most attractive business environments
      for pharma R&D centers in Europe
   •  The UK in particular offers an attractive environment, with above average scores on all
      location factors
   •  Smaller EU countries such as Switzerland, Denmark, The Netherlands and Sweden rank
      high on specific aspects

August 7, 2012                               www.global-arena.com                                         2
Global Consolidation, Restructuring and
   Global Competition for Talent
   •  Fierce global competition the pharmaceutical industry causes industry
      consolidation, rethink R&D strategy and reconsider global footprint
   •  Rising disposable income and health insurance schemes offer expansion
      opportunities in Asia
   •  Lack of skilled labour causes global competition for talent 
   •  When it comes to relation or expansion a 360-degree real-time view and
      performance monitoring of the market, business environment and local
      and global talent supply, including comparisons of tax systems is needed




August 7, 2012                     www.global-arena.com                           3
Overall Attractiveness Ranking of European
   Countries for Pharmaceutical R&D
                    UK	
                                                                                                                                                                           98%	
  
               France	
                                                                                                                                                                   94%	
  
           Germany	
                                                                                                                                                                     94%	
  
        Switzerland	
                                                                                                                                            75%	
  
                Spain	
                                                                                                                             65%	
  
       Netherlands	
                                                                                                                      60%	
  
                  Italy	
                                                                                                               59%	
  
             Sweden	
                                                                                                              57%	
  
           Denmark	
                                                                                                          54%	
  
             Belgium	
                                                                                                       54%	
  
              Austria	
                                                                                            50%	
  
              Finland	
                                                                             38%	
  
              Ireland	
                                                                 32%	
  
    Czech	
  Republic	
                                                             30%	
  
             Norway	
                                                              30%	
  
            Portugal	
                                              18%	
  
            Hungary	
                                     12%	
  
              Estonia	
                         7%	
  
                Latvia	
               4%	
  

                              0%	
              10%	
               20%	
     30%	
                40%	
      50%	
                60%	
               70%	
         80%	
     90%	
           100%	
  




August 7, 2012                                                                                    www.global-arena.com                                                                                       4
Key Findings
                                                                           UK	
  
                                                               Switzerland	
  
   •  The United Kingdom, France and Germany                        Sweden	
  
                                                                       Spain	
  
      offer the most attractive business                           Portugal	
  
      environments for pharma R&D centers in                        Norway	
  
                                                              Netherlands	
  
      Europe. All three show competitive conditions                    Latvia	
  

      in terms of market, talent and accessibility                       Italy	
  
                                                                     Ireland	
  
      factors
                                                     Hungary	
  
                                                                  Germany	
  
   •  The UK in particular offers an attractive                       France	
  

      environment, with above average scores on                      Finland	
  
                                                                     Estonia	
  
      all location factors
                                       Denmark	
  
                                                           Czech	
  Republic	
  
   •  Besides the biggest populated EU countries,                   Belgium	
  

      Switzerland rank high due to its opportunities                 Austria	
  


      for collaboration with universities
                       Compe22on	
  and	
  Mass	
  
                                                                 Tax	
  Incen2ves	
  
                                                                 Industry-­‐University	
  Interac2on	
  
   •  Smaller EU countries such as Denmark,                      Talent	
  Supply	
  
                                                                 World	
  Class	
  Knowledge	
  
      The Netherlands and Sweden rank high on                    Qualitz	
  of	
  Life	
  
                                                                 Interna2onal	
  Connec2vity	
  
      specific aspects
                                           Quality	
  of	
  ICT	
  
                                                                 Infrastructure	
  Capabili2es	
  




August 7, 2012                      www.global-arena.com                                                   5
Ranking Component: Competition and Mass

             Data Series Used
                               France	
                                                                                              98%	
  
                                                                  UK	
                                                                                           96%	
  
   • Company information on locations
                                                         Germany	
                                                                                              95%	
  
   of European R&D centers of listed                            Italy	
                                                                               84%	
  
   pharmaceuticals in the Forbes 200                  Switzerland	
                                                                               79%	
  
   Pharmaceuticals
                                           Spain	
                                                                   71%	
  
   • EU Cluster Oberservatory data on                Netherlands	
                                                      44%	
  

   cluster size (number of companies)
                     Belgium	
                                                    44%	
  
                                                          Hungary	
                                                  41%	
  
                                                            Ireland	
                                         34%	
  
                                                         Denmark	
                                         31%	
  
                                                            Austria	
                                   27%	
  
                  Analysis                        Czech	
  Republic	
                              24%	
  
   • France, the UK and Germany offer of all               Sweden	
                                23%	
  
   included European countries the most                     Estonia	
                           21%	
  
   attractive environment when it comes to a              Portugal	
                           20%	
  
   dynamic business environment. These                      Finland	
                         19%	
  
   countries are host to the most                          Norway	
                           18%	
  
   multinational pharmaceutical R&D centers                   Latvia	
                        18%	
  
   and have the biggest pharma clusters. 
                                  0%	
   10%	
   20%	
   30%	
   40%	
   50%	
   60%	
   70%	
   80%	
   90%	
   100%	
  
   • Compared to the bigger EU countries,
   Switzerland ranks also significantly high
   on these aspects 



August 7, 2012                                 www.global-arena.com                                                                                                          6
Ranking Component: Tax Incentives

             Data Series Used
                                  France	
                                                                                                        100%	
  
                                                     Czech	
  Republic	
                                                                                              78%	
  
   • OECD data on:
                                           Belgium	
                                                                                          76%	
  
        • Direct government funding of                        Sweden	
                                                                                         73%	
  
        business R&D projects
                                 Austria	
                                                                                    70%	
  
        • Indirect government support                            Spain	
                                                                             66%	
  
                                                               Ireland	
                                                                           64%	
  
        through R&D tax incentives 
                                                                     UK	
                                                                         62%	
  
                                                              Norway	
                                                                  54%	
  
                                                            Denmark	
                                                              49%	
  
                                                        Netherlands	
                                                        42%	
  
                                                             Hungary	
                                                  37%	
  

                   Analysis
                                 Portugal	
                                            32%	
  
                                                            Germany	
                                         28%	
  
   • When it comes to providing a financial
                                                               Finland	
                                 22%	
  
   supportive environment for business R&D
                                                               Estonia	
                                 22%	
  
   projects, France ranks on top in Europe. The
                                                                 Latvia	
                      13%	
  
   government offers a direct support of 15%
                                                         Switzerland	
                      10%	
  
   tax reduction, combined with an indirect tax
                                                                   Italy	
                  10%	
  
   incentive of 23% for R&D projects 
   • Latvia, Switzerland and Italy are the least                               0%	
     10%	
   20%	
   30%	
   40%	
   50%	
   60%	
   70%	
   80%	
   90%	
   100%	
  
   attractive in government support and
   incentives for R&D




August 7, 2012                                     www.global-arena.com                                                                                                                    7
Ranking Component: Industry-University Interaction

             Data Series Used
                       Switzerland	
                                                                                                   91%	
  
                                                           Finland	
                                                                                               89%	
  
   • INSEAD and WIPO Global
                                                                 UK	
                                                                                             88%	
  
   Innovation Index item on industry-                     Sweden	
                                                                                               86%	
  
   university research collaboration
                   Denmark	
                                                                                      79%	
  
                                                        Germany	
                                                                                  74%	
  
                                                          Belgium	
                                                                               74%	
  
                                                    Netherlands	
                                                                                72%	
  
                                                           Ireland	
                                                                   61%	
  
                                                           Austria	
                                                                58%	
  
                                                          Norway	
                                                               55%	
  
                  Analysis
                      Czech	
  Republic	
                                                   35%	
  
   • Of the countries included Switzerland               Portugal	
                                                34%	
  
   offers the most attractive R&D                        Hungary	
                                           28%	
  
   environment in terms of opportunities for               Estonia	
                                   21%	
  
   the industry to collaborate with                         France	
                          15%	
  
   universities
                                             Spain	
                         13%	
  
   •  Finland, the UK and Sweden follow
                       Italy	
              3%	
  
                                                             Latvia	
               3%	
  

                                                                           0%	
      10%	
   20%	
   30%	
   40%	
   50%	
   60%	
   70%	
   80%	
   90%	
   100%	
  




August 7, 2012
                                               www.global-arena.com                                                                                                            8
Ranking Component: Talent Supply

             Data Series Used
                                        UK	
                                                                                              99%	
  
                                                                    Italy	
                                                                                            97%	
  
   • Eurostat data on number of PhD’s
                                                             Germany	
                                                                                             92%	
  
   in Life Sciences
                                             France	
                                                                                84%	
  
                                                                  Spain	
                                                                             80%	
  
                                                                Ireland	
                                            34%	
  
                                                              Portugal	
                                            34%	
  
                                                                Austria	
                                           34%	
  
                    Analysis
                         Czech	
  Republic	
                                           34%	
  
   • A sustainable talent supply is becoming                   Sweden	
                                            33%	
  

   more and more a critical success factor                     Belgium	
                                          32%	
  

   for companies. The biggest populated EU                Switzerland	
                                          30%	
  

   countries such as the UK, Italy and                   Netherlands	
                                     27%	
  

   Germany offer the most attractive                            Finland	
                                  27%	
  

   environment since they host the largest                    Hungary	
                                    27%	
  

   domestic stocks of highly skilled labour in               Denmark	
                                    26%	
  
                                                               Norway	
                                   26%	
  
   life sciences
                                                                Estonia	
                               24%	
  
   • However, talent is mobile and countries
                                                                  Latvia	
                             23%	
  
   like Switzerland, with a relative low
   domestic supply, attract many EU talent                                      0%	
     10%	
   20%	
   30%	
   40%	
   50%	
   60%	
   70%	
   80%	
   90%	
   100%	
  
   with its high quality of life and significantly
   higher salaries



August 7, 2012                                      www.global-arena.com                                                                                                          9
Ranking Component: World Class Knowledge

             Data Series Used
                                      UK	
                                                                                                 99%	
  
                                                           Germany	
                                                                                                     98%	
  
   • QS World University Ranking for
                                                               France	
                                                                                        89%	
  
   Pharmacy and Pharmacology data                                 Italy	
                                                                                82%	
  
   on:
                                                 Switzerland	
                                                                          64%	
  
        • Number of listed universities in                      Spain	
                                                                   59%	
  

        top 200
                                             Belgium	
                                                          51%	
  
                                                              Austria	
                                               39%	
  
        • Total score on academic
                                                              Ireland	
                                               39%	
  
        ranking
                                              Finland	
                                              38%	
  
                                                             Sweden	
                                             35%	
  
                                                           Denmark	
                                              34%	
  
                                                       Netherlands	
                                             33%	
  
                                                    Czech	
  Republic	
                                24%	
  
                   Analysis
                                Portugal	
                            19%	
  
   • The UK and Germany rank on top on                       Norway	
                             19%	
  
   proximity to world class knowledge                           Latvia	
                          19%	
  
   institutes in Pharmacy and Pharmacology
                 Hungary	
                             19%	
  
   • The UK is host to 25 listed universities in              Estonia	
                           19%	
  
   this area, with Cambridge, Oxford and
                                                                              0%	
     10%	
   20%	
   30%	
   40%	
   50%	
   60%	
   70%	
   80%	
   90%	
   100%	
  
   Imperial College scoring top 10 position in
   the global ranking




August 7, 2012                                     www.global-arena.com                                                                                                            10
Ranking Component: Quality of Life

                 Data Series Used
                         Germany	
                                                                                               92%	
  
                                                                    Italy	
                                                                                        91%	
  
   • Lonely Planet data on number of restaurants,
                                                                  France	
                                                                                        89%	
  
   shops and activities
   • UNESCO data on number of natural and                        Austria	
                                                                              77%	
  
   cultural heritage sites
                              Switzerland	
                                                                                  77%	
  
   • Yale University Environmental Performance                  Sweden	
                                                                               76%	
  
   Index
                                                          Spain	
                                                                             76%	
  
   • WHO data on number of homicides
                                 UK	
                                                                            75%	
  
   • Numbeo data on cost of housing and local         Czech	
  Republic	
                                                                   49%	
  
   purchase power
                                      Netherlands	
                                                                      49%	
  
                                                               Norway	
                                                              42%	
  
                                                           Denmark	
                                                            40%	
  
                     Analysis
                                  Finland	
                                                    35%	
  
   • Countries such as Germany, Italy and                        Ireland	
                                                   34%	
  
   France offer the most most attractive                       Portugal	
                                          25%	
  
   talent environment with regards to the                      Hungary	
                                         21%	
  
   quality of life. These countries offer a                    Belgium	
                               14%	
  
   favourable environment in terms of                              Latvia	
                       8%	
  
                                                                 Estonia	
               1%	
  
   entertainment, healthy environment,
   security and cost of living
                                                 0%	
         10%	
   20%	
   30%	
   40%	
   50%	
   60%	
   70%	
   80%	
   90%	
   100%	
  
   • Austria, Switzerland, Sweden, Spain and
   the UK follow




August 7, 2012                                      www.global-arena.com                                                                                                        11
Ranking Component: International Connectivity

             Data Series Used                             Germany	
                                                                                                96%	
  
                                                              France	
                                                                                            95%	
  
   • Flight Connectivity Index data on                             UK	
                                                                                           94%	
  
   number of international flights
                    Netherlands	
                                                                                     83%	
  
                                                                 Italy	
                                                                                83%	
  
                                                            Belgium	
                                                                         68%	
  
                                                               Spain	
                                                                       67%	
  
                                                       Switzerland	
                                                               58%	
  
                                                             Austria	
                                                         53%	
  
                                                          Denmark	
                                                  35%	
  
                                                           Portugal	
                                         29%	
  
                   Analysis
                       Czech	
  Republic	
                                        29%	
  
   • Germany, France and the UK rank on top                Hungary	
                                       26%	
  
   in terms of international air connectivity.              Sweden	
                                   24%	
  
                                                             Finland	
                           19%	
  
   For international frequent flyers these
                                                            Norway	
                             18%	
  
   countries offer the most international
                                                               Latvia	
                      14%	
  
   flights in Europe 
                                                             Ireland	
                       14%	
  
   • Compared to the biggest EU countries,                   Estonia	
                  9%	
  
   The Netherlands ranks high on this
                                                                             0%	
   10%	
   20%	
   30%	
   40%	
   50%	
   60%	
   70%	
   80%	
   90%	
   100%	
  
   aspect too




August 7, 2012                                   www.global-arena.com                                                                                                        12
Ranking Component: Quality of ICT"

                 Data Series Used
                        Denmark	
                                                                                                   94%	
  
                                                       Switzerland	
                                                                                                 93%	
  
   • World Economic Forum Global
                                                                   UK	
                                                                                              93%	
  
   Information Technology Report items on:
                                                            Norway	
                                                                                       85%	
  
         • Mobile network coverage rate
                                                      Netherlands	
                                                                                   79%	
  
         • Secure internet providers
                       Sweden	
                                                                                 77%	
  
         • International internet bandwith
                  Finland	
                                                                     63%	
  
                                                            Belgium	
                                                                    60%	
  
                                                             Estonia	
                                                         50%	
  
                                                          Germany	
                                                       43%	
  
                                                             Ireland	
                                          35%	
  
                                                               Spain	
                                      34%	
  

                     Analysis
                                   Italy	
                                    33%	
  
                                                             Austria	
                                    31%	
  
   •  Denmark, Switzerland, and the UK
                                                   Czech	
  Republic	
                                   30%	
  
   scores highest on aspects of quality of
                                                              France	
                                26%	
  
   ICT 
                                                   Hungary	
                  7%	
  
   • Of all included EU countries                          Portugal	
                 7%	
  
   The Netherlands offers the most attractive                  Latvia	
             5%	
  
   business environment when it comes to
                                                                             0%	
   10%	
   20%	
   30%	
   40%	
   50%	
   60%	
   70%	
   80%	
   90%	
   100%	
  
   international internet bandwith




August 7, 2012                                  www.global-arena.com                                                                                                            13
Ranking Component: Infrastructure Capabilities

                 Data Series Used
                             France	
                                                                                           92%	
  
                                                           Germany	
                                                                                              92%	
  
   • World Economic Forum Global
                                                        Switzerland	
                                                                                      86%	
  
   Competitiveness Report items on
                                                                    UK	
                                                                                83%	
  
   Infrastructure:
                                             Spain	
                                                                               81%	
  
          • Roads
                                     Netherlands	
                                                                             76%	
  
          • Railroads
                                     Denmark	
                                                                        70%	
  
          • Airport
                                          Finland	
                                                              64%	
  
          • Available airline seat kilometers
                Austria	
                                                           60%	
  
                                                             Sweden	
                                                            59%	
  
                                                             Belgium	
                                                           59%	
  
                                                            Portugal	
                                                 46%	
  
                                                              Ireland	
                                     25%	
  
                     Analysis
                      Czech	
  Republic	
                                     25%	
  
   •  With regards to the infrastructure                     Norway	
                                17%	
  
   capabilities countries such as France,                         Italy	
                         14%	
  
   Germany, Switzerland, the UK and Spain                       Latvia	
                 8%	
  
   offer the most attractive business                         Estonia	
                7%	
  
   environment: these countries all offer a                 Hungary	
                4%	
  
   state of the art road, rail and air                                        0%	
   10%	
   20%	
   30%	
   40%	
   50%	
   60%	
   70%	
   80%	
   90%	
   100%	
  
   infrastructure allowing people to travel
   easy




August 7, 2012                                   www.global-arena.com                                                                                                       14
Have a look yourself
   Looking for the most
   attractive location
   with the most competitive
   R&D business
   environment? 

   Click here to visit the
   interactive analysis and to
   adjust the sliders and to
   learn more about our
   Go-global Enterprise
   Location Planning services




August 7, 2012                    www.global-arena.com   15
Appendices
              •  About Global-Arena.com
                            •  Data sources




August 7, 2012   www.global-arena.com                    16
Global-Arena.com
      Global-Arena.com is the leading secure online matching platform that brings together companies,
      investors and business locations worldwide. Global-Arena.com offers innovative digital services and
      gives them a data advantage to save cost and time. With it’s Go-global solutions
      Enterprise Location Planning and Economic Development Planning Global-Arena.com is able to
      provide companies and governments an integrated 360-degree view and comparative advantages
      analysis of the market, business environment and talent supply by:
      •  Analysing and comparing the attractiveness of business locations in support of its clients growth
      strategies
      •  Searching and analysing growth, expansion and relocation opportunities worldwide
      •  Visualising scenarios of business and policy impacts based on real time economic statistics, trends
      and forecasts

      To learn more about how Global-Arena.com can support your site selection or location promotion
      processes, visit our website www.global-arena.com or contact:

                                                 Peter Storm CEO
                                             info@global-arena.com
                                             www.global-arena.com




August 7, 2012                                  www.global-arena.com                                           17
Our Approach: From Long to Short List




August 7, 2012           www.global-arena.com   18
Data Sources used per Location Factor
   Market	
  Factors	
            Sources	
                                  Talent	
  Factors	
                   Sources	
                                     Accessibility	
                     Sources	
  
                                                                                                                                                                 Factors	
  
   Compe22on	
  and	
  Mass	
     Company	
  website	
                       Talent	
  Supply	
                    Eurostat	
  data	
  on	
  number	
  of	
      Interna2onal	
  Connec2vity	
       Flight	
  Connec2vity	
  Index	
  data	
  
                                  informa2on	
  on	
  biotech	
  R&D	
                                             PhD’s	
  in	
  Life	
  Sciences	
                                                 on	
  number	
  of	
  interna2onal	
  
                                  sites	
  of	
  the	
  listed	
                                                                                                                                     flights	
  
                                  Pharmaceu2cals	
  in	
  the	
  
                                  Forbes	
  500	
  Biggest	
  
                                  Companies	
  
                                  EU	
  Cluster	
  Observatory	
  data	
  
                                  on	
  the	
  number	
  of	
  
                                  pharmaceu2cal	
  enterprises	
  

   Tax	
  Incen2ves	
             OECD	
  data	
  on:	
                      World	
  Class	
  Knowledge	
         QS	
  World	
  University	
  Ranking	
        Quality	
  of	
  ICT	
              World	
  Economic	
  Forum	
  
                                  • Direct	
  government	
  funding	
                                              for	
  Pharmacy	
  and	
                                                          Global	
  Informa2on	
  
                                  of	
  business	
  R&D	
  projects	
                                              Pharmacology	
  data	
  on:	
                                                     Technology	
  Report	
  items	
  on:	
  
                                  • Indirect	
  government	
                                                       • Number	
  of	
  listed	
                                                        • 	
  Mobile	
  network	
  coverage	
  
                                  support	
  through	
  R&D	
  tax	
                                               universi2es	
                                                                     • 	
  secure	
  internet	
  providers	
  
                                  incen2ves	
                                                                      • Academic	
  score	
  	
                                                         • 	
  interna2onal	
  internet	
  
                                                                                                                                                                                                     bandwith	
  



   Industry-­‐University	
        INSEAD	
  and	
  WIPO	
  Global	
          Quality	
  of	
  Life	
               Lonely	
  Planet	
  data	
  on:	
             Infrastructure	
  Capabili2es	
     World	
  Economic	
  Forum	
  
   Interac2on	
                   Innova2on	
  Index,	
  item	
  on	
                                              • Number	
  of	
  restaurants	
                                                   Global	
  Compe22veness	
  
                                  industry-­‐university	
  research	
                                              • Number	
  of	
  shops	
                                                         Report	
  2011-­‐2012	
  items	
  on	
  
                                  collabora2on	
                                                                   • Number	
  of	
  ac2vi2es	
                                                      infrastructure	
  quality:	
  
                                                                                                                   UNESCO	
  data	
  on	
  cultural	
  and	
                                         • 	
  Roads	
  
                                                                                                                   natural	
  heritage	
  sites	
                                                    • 	
  Railroads	
  
                                                                                                                   Yale	
  University	
                                                              • 	
  Airports	
  
                                                                                                                   Environmental	
  Performance	
                                                    • 	
  Available	
  airline	
  seat	
  
                                                                                                                   Index	
                                                                           kilometers	
  
                                                                                                                   WHO	
  data	
  on	
  number	
  of	
  
                                                                                                                   homicides	
  
                                                                                                                   Numbeo	
  data	
  on	
  costs	
  of	
  
                                                                                                                   housing	
  and	
  local	
  purchase	
  
                                                                                                                   power	
  




August 7, 2012                                                                                           www.global-arena.com                                                                                                                     19

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Most Attractive Pharma R&D Location in Europe

  • 1. August 7, 2012 www.global-arena.com 1
  • 2. Executive Summary Location matter to business. Framework conditions, including market, talent and infrastructure factors affect business decisions when it comes to R&D center site selection. Recent reports and the PwC Global CEO Survey 2012 show that in particular talent related aspects are becoming more and more critical. Despite a skilled labour force, high quality of life and a state of the art research Infrastructure Europe is hit hard by restructure plans closing or relocating pharmaceutical R&D centers in favour of US or Asian locations. As part of its Go-global solutions Global-Arena.com’s interactive analysis to the most attractive locations for pharmaceutical R&D centers location in Europe unveils the comparative advantages of 19 European economies: •  The United Kingdom, France and Germany offer the most attractive business environments for pharma R&D centers in Europe •  The UK in particular offers an attractive environment, with above average scores on all location factors •  Smaller EU countries such as Switzerland, Denmark, The Netherlands and Sweden rank high on specific aspects August 7, 2012 www.global-arena.com 2
  • 3. Global Consolidation, Restructuring and Global Competition for Talent •  Fierce global competition the pharmaceutical industry causes industry consolidation, rethink R&D strategy and reconsider global footprint •  Rising disposable income and health insurance schemes offer expansion opportunities in Asia •  Lack of skilled labour causes global competition for talent •  When it comes to relation or expansion a 360-degree real-time view and performance monitoring of the market, business environment and local and global talent supply, including comparisons of tax systems is needed August 7, 2012 www.global-arena.com 3
  • 4. Overall Attractiveness Ranking of European Countries for Pharmaceutical R&D UK   98%   France   94%   Germany   94%   Switzerland   75%   Spain   65%   Netherlands   60%   Italy   59%   Sweden   57%   Denmark   54%   Belgium   54%   Austria   50%   Finland   38%   Ireland   32%   Czech  Republic   30%   Norway   30%   Portugal   18%   Hungary   12%   Estonia   7%   Latvia   4%   0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   August 7, 2012 www.global-arena.com 4
  • 5. Key Findings UK   Switzerland   •  The United Kingdom, France and Germany Sweden   Spain   offer the most attractive business Portugal   environments for pharma R&D centers in Norway   Netherlands   Europe. All three show competitive conditions Latvia   in terms of market, talent and accessibility Italy   Ireland   factors Hungary   Germany   •  The UK in particular offers an attractive France   environment, with above average scores on Finland   Estonia   all location factors Denmark   Czech  Republic   •  Besides the biggest populated EU countries, Belgium   Switzerland rank high due to its opportunities Austria   for collaboration with universities Compe22on  and  Mass   Tax  Incen2ves   Industry-­‐University  Interac2on   •  Smaller EU countries such as Denmark, Talent  Supply   World  Class  Knowledge   The Netherlands and Sweden rank high on Qualitz  of  Life   Interna2onal  Connec2vity   specific aspects Quality  of  ICT   Infrastructure  Capabili2es   August 7, 2012 www.global-arena.com 5
  • 6. Ranking Component: Competition and Mass Data Series Used France   98%   UK   96%   • Company information on locations Germany   95%   of European R&D centers of listed Italy   84%   pharmaceuticals in the Forbes 200 Switzerland   79%   Pharmaceuticals Spain   71%   • EU Cluster Oberservatory data on Netherlands   44%   cluster size (number of companies) Belgium   44%   Hungary   41%   Ireland   34%   Denmark   31%   Austria   27%   Analysis Czech  Republic   24%   • France, the UK and Germany offer of all Sweden   23%   included European countries the most Estonia   21%   attractive environment when it comes to a Portugal   20%   dynamic business environment. These Finland   19%   countries are host to the most Norway   18%   multinational pharmaceutical R&D centers Latvia   18%   and have the biggest pharma clusters. 0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   • Compared to the bigger EU countries, Switzerland ranks also significantly high on these aspects August 7, 2012 www.global-arena.com 6
  • 7. Ranking Component: Tax Incentives Data Series Used France   100%   Czech  Republic   78%   • OECD data on: Belgium   76%   • Direct government funding of Sweden   73%   business R&D projects Austria   70%   • Indirect government support Spain   66%   Ireland   64%   through R&D tax incentives UK   62%   Norway   54%   Denmark   49%   Netherlands   42%   Hungary   37%   Analysis Portugal   32%   Germany   28%   • When it comes to providing a financial Finland   22%   supportive environment for business R&D Estonia   22%   projects, France ranks on top in Europe. The Latvia   13%   government offers a direct support of 15% Switzerland   10%   tax reduction, combined with an indirect tax Italy   10%   incentive of 23% for R&D projects • Latvia, Switzerland and Italy are the least 0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   attractive in government support and incentives for R&D August 7, 2012 www.global-arena.com 7
  • 8. Ranking Component: Industry-University Interaction Data Series Used Switzerland   91%   Finland   89%   • INSEAD and WIPO Global UK   88%   Innovation Index item on industry- Sweden   86%   university research collaboration Denmark   79%   Germany   74%   Belgium   74%   Netherlands   72%   Ireland   61%   Austria   58%   Norway   55%   Analysis Czech  Republic   35%   • Of the countries included Switzerland Portugal   34%   offers the most attractive R&D Hungary   28%   environment in terms of opportunities for Estonia   21%   the industry to collaborate with France   15%   universities Spain   13%   •  Finland, the UK and Sweden follow Italy   3%   Latvia   3%   0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   August 7, 2012 www.global-arena.com 8
  • 9. Ranking Component: Talent Supply Data Series Used UK   99%   Italy   97%   • Eurostat data on number of PhD’s Germany   92%   in Life Sciences France   84%   Spain   80%   Ireland   34%   Portugal   34%   Austria   34%   Analysis Czech  Republic   34%   • A sustainable talent supply is becoming Sweden   33%   more and more a critical success factor Belgium   32%   for companies. The biggest populated EU Switzerland   30%   countries such as the UK, Italy and Netherlands   27%   Germany offer the most attractive Finland   27%   environment since they host the largest Hungary   27%   domestic stocks of highly skilled labour in Denmark   26%   Norway   26%   life sciences Estonia   24%   • However, talent is mobile and countries Latvia   23%   like Switzerland, with a relative low domestic supply, attract many EU talent 0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   with its high quality of life and significantly higher salaries August 7, 2012 www.global-arena.com 9
  • 10. Ranking Component: World Class Knowledge Data Series Used UK   99%   Germany   98%   • QS World University Ranking for France   89%   Pharmacy and Pharmacology data Italy   82%   on: Switzerland   64%   • Number of listed universities in Spain   59%   top 200 Belgium   51%   Austria   39%   • Total score on academic Ireland   39%   ranking Finland   38%   Sweden   35%   Denmark   34%   Netherlands   33%   Czech  Republic   24%   Analysis Portugal   19%   • The UK and Germany rank on top on Norway   19%   proximity to world class knowledge Latvia   19%   institutes in Pharmacy and Pharmacology Hungary   19%   • The UK is host to 25 listed universities in Estonia   19%   this area, with Cambridge, Oxford and 0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   Imperial College scoring top 10 position in the global ranking August 7, 2012 www.global-arena.com 10
  • 11. Ranking Component: Quality of Life Data Series Used Germany   92%   Italy   91%   • Lonely Planet data on number of restaurants, France   89%   shops and activities • UNESCO data on number of natural and Austria   77%   cultural heritage sites Switzerland   77%   • Yale University Environmental Performance Sweden   76%   Index Spain   76%   • WHO data on number of homicides UK   75%   • Numbeo data on cost of housing and local Czech  Republic   49%   purchase power Netherlands   49%   Norway   42%   Denmark   40%   Analysis Finland   35%   • Countries such as Germany, Italy and Ireland   34%   France offer the most most attractive Portugal   25%   talent environment with regards to the Hungary   21%   quality of life. These countries offer a Belgium   14%   favourable environment in terms of Latvia   8%   Estonia   1%   entertainment, healthy environment, security and cost of living 0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   • Austria, Switzerland, Sweden, Spain and the UK follow August 7, 2012 www.global-arena.com 11
  • 12. Ranking Component: International Connectivity Data Series Used Germany   96%   France   95%   • Flight Connectivity Index data on UK   94%   number of international flights Netherlands   83%   Italy   83%   Belgium   68%   Spain   67%   Switzerland   58%   Austria   53%   Denmark   35%   Portugal   29%   Analysis Czech  Republic   29%   • Germany, France and the UK rank on top Hungary   26%   in terms of international air connectivity. Sweden   24%   Finland   19%   For international frequent flyers these Norway   18%   countries offer the most international Latvia   14%   flights in Europe Ireland   14%   • Compared to the biggest EU countries, Estonia   9%   The Netherlands ranks high on this 0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   aspect too August 7, 2012 www.global-arena.com 12
  • 13. Ranking Component: Quality of ICT" Data Series Used Denmark   94%   Switzerland   93%   • World Economic Forum Global UK   93%   Information Technology Report items on: Norway   85%   • Mobile network coverage rate Netherlands   79%   • Secure internet providers Sweden   77%   • International internet bandwith Finland   63%   Belgium   60%   Estonia   50%   Germany   43%   Ireland   35%   Spain   34%   Analysis Italy   33%   Austria   31%   •  Denmark, Switzerland, and the UK Czech  Republic   30%   scores highest on aspects of quality of France   26%   ICT Hungary   7%   • Of all included EU countries Portugal   7%   The Netherlands offers the most attractive Latvia   5%   business environment when it comes to 0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   international internet bandwith August 7, 2012 www.global-arena.com 13
  • 14. Ranking Component: Infrastructure Capabilities Data Series Used France   92%   Germany   92%   • World Economic Forum Global Switzerland   86%   Competitiveness Report items on UK   83%   Infrastructure: Spain   81%   • Roads Netherlands   76%   • Railroads Denmark   70%   • Airport Finland   64%   • Available airline seat kilometers Austria   60%   Sweden   59%   Belgium   59%   Portugal   46%   Ireland   25%   Analysis Czech  Republic   25%   •  With regards to the infrastructure Norway   17%   capabilities countries such as France, Italy   14%   Germany, Switzerland, the UK and Spain Latvia   8%   offer the most attractive business Estonia   7%   environment: these countries all offer a Hungary   4%   state of the art road, rail and air 0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%   infrastructure allowing people to travel easy August 7, 2012 www.global-arena.com 14
  • 15. Have a look yourself Looking for the most attractive location with the most competitive R&D business environment? Click here to visit the interactive analysis and to adjust the sliders and to learn more about our Go-global Enterprise Location Planning services August 7, 2012 www.global-arena.com 15
  • 16. Appendices •  About Global-Arena.com •  Data sources August 7, 2012 www.global-arena.com 16
  • 17. Global-Arena.com Global-Arena.com is the leading secure online matching platform that brings together companies, investors and business locations worldwide. Global-Arena.com offers innovative digital services and gives them a data advantage to save cost and time. With it’s Go-global solutions Enterprise Location Planning and Economic Development Planning Global-Arena.com is able to provide companies and governments an integrated 360-degree view and comparative advantages analysis of the market, business environment and talent supply by: •  Analysing and comparing the attractiveness of business locations in support of its clients growth strategies •  Searching and analysing growth, expansion and relocation opportunities worldwide •  Visualising scenarios of business and policy impacts based on real time economic statistics, trends and forecasts To learn more about how Global-Arena.com can support your site selection or location promotion processes, visit our website www.global-arena.com or contact: Peter Storm CEO info@global-arena.com www.global-arena.com August 7, 2012 www.global-arena.com 17
  • 18. Our Approach: From Long to Short List August 7, 2012 www.global-arena.com 18
  • 19. Data Sources used per Location Factor Market  Factors   Sources   Talent  Factors   Sources   Accessibility   Sources   Factors   Compe22on  and  Mass   Company  website   Talent  Supply   Eurostat  data  on  number  of   Interna2onal  Connec2vity   Flight  Connec2vity  Index  data   informa2on  on  biotech  R&D   PhD’s  in  Life  Sciences   on  number  of  interna2onal   sites  of  the  listed   flights   Pharmaceu2cals  in  the   Forbes  500  Biggest   Companies   EU  Cluster  Observatory  data   on  the  number  of   pharmaceu2cal  enterprises   Tax  Incen2ves   OECD  data  on:   World  Class  Knowledge   QS  World  University  Ranking   Quality  of  ICT   World  Economic  Forum   • Direct  government  funding   for  Pharmacy  and   Global  Informa2on   of  business  R&D  projects   Pharmacology  data  on:   Technology  Report  items  on:   • Indirect  government   • Number  of  listed   •   Mobile  network  coverage   support  through  R&D  tax   universi2es   •   secure  internet  providers   incen2ves   • Academic  score     •   interna2onal  internet   bandwith   Industry-­‐University   INSEAD  and  WIPO  Global   Quality  of  Life   Lonely  Planet  data  on:   Infrastructure  Capabili2es   World  Economic  Forum   Interac2on   Innova2on  Index,  item  on   • Number  of  restaurants   Global  Compe22veness   industry-­‐university  research   • Number  of  shops   Report  2011-­‐2012  items  on   collabora2on   • Number  of  ac2vi2es   infrastructure  quality:   UNESCO  data  on  cultural  and   •   Roads   natural  heritage  sites   •   Railroads   Yale  University   •   Airports   Environmental  Performance   •   Available  airline  seat   Index   kilometers   WHO  data  on  number  of   homicides   Numbeo  data  on  costs  of   housing  and  local  purchase   power   August 7, 2012 www.global-arena.com 19