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Migraine and genetic vasculopathies. ,[object Object],[object Object],[object Object]
CADASIL ,[object Object],[object Object]
[object Object],[object Object],CADASIL
[object Object],[object Object],CADASIL
 
Axial FLAIR ( A – C ) and T2*-weighted gradient ( D ) MR images of CADASIL patients. Complete MR imaging spectrum of CADASIL: confluent hyperintensities ( A – C ), lacunar infarcts ( A, arrow ), subcortical lacunar lesions ( B, arrow ), and microbleeds ( D, arrow ).
[object Object],[object Object],[object Object],CADASIL
[object Object],[object Object],[object Object],CADASIL
MELAS
[object Object],[object Object],[object Object],MELAS
[object Object],[object Object],[object Object],[object Object],MELAS
[object Object],[object Object],[object Object],MELAS
 
[object Object],[object Object],[object Object],MELAS
Other genetic vasculopathies  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MTHFR and Migraine with Aura Vit B12 Vit B12 NADPH NADP + MTHFR  methylenetetrahydrofolate reductase  DHF dihydrofolate THF tetrahydrofolate 5,10-methylene-THF 5,10-methylenetetrahydrofolate  5-methyl-THF  5-methyltetrahydrofolate  MTR methionine synthase  SAH S-adenosylhomocysteine NADPH reduced form of Nicotinamide adenine dinucleotide phosphate NADP+ oxidized form of Nicotinamide adenine dinucleotide phosphate SAM S-Adenosyl methionine
 
Migraine and Stroke (Cause or Case?) ,[object Object],[object Object],[object Object],[object Object],[object Object]

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Di Lorenzo Cherubino. Cefalea e vasculopatie genetiche. ASMaD 2011

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  • 7. Axial FLAIR ( A – C ) and T2*-weighted gradient ( D ) MR images of CADASIL patients. Complete MR imaging spectrum of CADASIL: confluent hyperintensities ( A – C ), lacunar infarcts ( A, arrow ), subcortical lacunar lesions ( B, arrow ), and microbleeds ( D, arrow ).
  • 8.
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  • 10. MELAS
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  • 17. MTHFR and Migraine with Aura Vit B12 Vit B12 NADPH NADP + MTHFR methylenetetrahydrofolate reductase DHF dihydrofolate THF tetrahydrofolate 5,10-methylene-THF 5,10-methylenetetrahydrofolate 5-methyl-THF 5-methyltetrahydrofolate MTR methionine synthase SAH S-adenosylhomocysteine NADPH reduced form of Nicotinamide adenine dinucleotide phosphate NADP+ oxidized form of Nicotinamide adenine dinucleotide phosphate SAM S-Adenosyl methionine
  • 18.  
  • 19.