1. New Discoveries On Gene Regulation in the Evolution of the Vertebrate BrainNew Link Found Between Obesity and Insulin Resistance MARIA CAMILA PELAEZ MEDICINE STUDENT BIOLOGY MOLECULAR

4. INTRODUCTION The mechanism of translation is the process by which a mRNA molecule will form a protein can have different characters, plus it is modulated by a splicing mechanism that allows gene regulation, as we shall see is news.

5. New Discoveries On Gene Regulation in the Evolution of the Vertebrate Brain .The alternative splicing is primarily based on splicing and the combination of extron for the formation of proteins and thus detect errors in the genome.

6. Discover a new protein called Nova 1 (neuro-oncological ventral antigen) which have as main function to modulate the activity of a set of genes involved in the formation and structure of the nervous system.

7. is important to note that this study is based only in vertebrates and that its genome is very complex and the combination of extrons to be performed only as a means of regulating them, what does not happen with invertebrates

8. the study noted that in addition to that each gene has its own code, also has specific proteins to be expressed in every tissue and at any time.

9. My opinion This study is very interesting as it gives us new knowledge about the evolution and development of the nervous system, and besides it allows to know more thoroughly as has been the true evolution of vertebrates.

10. New Link Found Between Obesity and Insulin Resistance In the process of transcription, generate new proteins which can serve on the reserve of fat in the liver which is a major predisposing to the development of insulin resistance and this would lead to future diabetes.

11. It was discovered that RNA splicing proteins are decreased in obese people giving us a reasonably accurate to think exactly where the process is altered in the genome

12. This study encourages investigation of new genes that may participate in the process and thus to have greater certainty of what is actually causing the diseases.

13. conclude that the splicing plays an important role in regulation cell and is an important cofactor for expression of insulin resistance leading to more advanced states the person who owns it

14. MY OPINION This study is interesting because it allows us to adopt good habits of life by preventing more triggers without neglecting gene regulation.

15. MEDICAL UTILITY Establishing an early diagnosis of hereditary genetic diseases in some cases have not been well studied, but would help us to give adequate attention to the patient who has

16. Through this we can determine the changes that occur in pathologies that mainly with alterations of the brain and the regulation of such neuronal activity.

17. Well lifestyles may prevent metabolic abnormalities and thus reduce the percentage of people who may suffer, providing better quality of life for the population

18. BIBLIOGRAPHY http://www.ub.edu/medicina/program/4quart/esp/Nervios-tradES.pdf http://www.sciencedaily.com/releases/2011/03/110324154247.htm http://www.sciencedaily.com/releases/2011/08/110802125551.htm

19. THANK YOU