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PE DIA TRIC C OMPL IA NC E




 FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com   1
Table of C ontents


SECTION                                SECTION TITLE                                           SLIDE#

  1                         Liquid Vs. Solid Dosage Forms                                        4
  2                               Special Considerations                                         4

  3                           The Unpleasant Experience                                          5

  4                              Children Taking Charge                                          6

  5                                 Flavoring Can Help!                                          7

  6                         The Importance of Adherence                                          8

  7                                   Taste and Choice                                           9


          FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com            2
L iquid Vs. Solid Dosage Forms


               Until a child is around 8 years old, swallowing pills can be challenging. This is
               often due to the smaller structure of a child's esophagus. Therefore, children
               under the age of 8 are typically prescribed liquid medications.

               While liquids are easier to administer, getting the child to swallow is a whole
               different story. For the pediatric population, taste and poor palatability are
               identified among the most significant barriers to adherence.

               Focus groups and nationwide surveys show 67% of mothers say their children
               either dislike or hate the taste of liquid medications.




FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com               3
Special C onsiderations

   While it may seem the child is being difficult, this rejection is rarely the result of a child’s
   desire to be picky or fussy. Rather, it is an actual physical inability to swallow an
   unpalatable substance.


   Children have a greater number of taste buds than adults. These taste buds regenerate
   every two weeks. As with many of the senses, taste becomes altered as a function of the
   aging process. That explains why most children find certain flavors to be too 'strong'
   when adults do not.


   Children, and infants in particular, are most sensitive to bitter and sweet tastes, making
   them less likely to swallow bitter-tasting medications and also more prone to liking
   sweeter, fruity flavors.


   Unfortunately the active ingredients in many medications often taste bitter and/or have
   a pungent smell. Masking the taste of these medications can often be difficult simply
   because the innate flavor is so overpowering.



FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com               4
The Unpleasant E xperience




Unpleasant tasting medications can result in particularly poor
adherence in children. Struggling with or forcing a child to take
an unpleasant tasting medication adds additional strain to the
already unpleasant state of feeling sick. It can also predispose
children to believe that all medications, regardless of taste or
smell, are unpleasant, giving them a negative impression of all
medicinal treatments. Like most of us, children will resist
unpleasant experiences.


                    FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com   5
C hildren Taking C harge
                          Not surprisingly, children embrace pleasant experiences including
                          pleasant tastes.


                          Studies have shown that allowing a child to play an active role in
                          choosing the flavor of their medication makes him/her more
                          compliant to drug regimens. Showing a child that they have the
                          capability to modify the flavor of a medication to a flavor of their
                          liking grants them some authority in their treatment.


                          Flavoring not only helps mask the unpleasant taste of a medication
                          but also customizes the medication to satisfy the individual child’s
                          taste preferences. Allowing them to choose how their medication
                          will taste encourages a child to take charge of their own health and
                          is yet another way to promote adherence .




FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com               6
Flavoring C an Help!

                                                The addition of a safe pharmaceutical
                                                flavoring to medicine can greatly improve a
                                                child's sensations of taste and smell, leading
                                                to acceptance and therefore compliance. In
                                                fact, studies show that proper flavoring can
                                                increase compliance in children from 53% to
                                                over 90%. As a pharmacist, simply
                                                recommend FLAVORx when dispensing a
                                                child's medication. The process is
                                                scientifically-proven, safe and effective.
                                                Unlike the addition of food or drink,
                                                FLAVORx flavoring available at the pharmacy
                                                will not adversely affect a medicine's
                                                stability, efficacy, or potency.




FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com               7
The Importance of A dherence


Oftentimes a parent's frustration with giving a bad tasting medication will cause them to stop treatment as
soon as their child’s symptoms go away, thus not completing the full course of medication as prescribed by
their physician.


This is a classic example of poor treatment adherence. Adherence means adhering to or following one’s
treatment plan as specified by a physician. Essentially, obeying medical advice.
That means taking the correct dose of your medication at the correct time,
for the correct duration, and exactly as prescribed.


Adherence is very important for successful health outcomes.
Conversely, non-adherence can lead to: continued disease
processes, health complications, hospitalization,
additional doctor visits, therapeutic drug changes,
spread of illness, slower recovery, and absenteeism
to name a few.




                   FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com         8
Taste and C hoice


Medications successfully taken because of
flavoring are far less physically, emotionally,
and financially exhausting. For children, taste
and choice may be the only motivation to take
a medication and complete a full treatment
program.


Improving the taste of a medication and
allowing children a choice as to how their
medication will taste can improve therapy
adherence, leading to both improved clinical
and economic outcomes.




                   FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com   9
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FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com   10

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Pediatric Compliance

  • 1. PE DIA TRIC C OMPL IA NC E FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 1
  • 2. Table of C ontents SECTION SECTION TITLE SLIDE# 1 Liquid Vs. Solid Dosage Forms 4 2 Special Considerations 4 3 The Unpleasant Experience 5 4 Children Taking Charge 6 5 Flavoring Can Help! 7 6 The Importance of Adherence 8 7 Taste and Choice 9 FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 2
  • 3. L iquid Vs. Solid Dosage Forms Until a child is around 8 years old, swallowing pills can be challenging. This is often due to the smaller structure of a child's esophagus. Therefore, children under the age of 8 are typically prescribed liquid medications. While liquids are easier to administer, getting the child to swallow is a whole different story. For the pediatric population, taste and poor palatability are identified among the most significant barriers to adherence. Focus groups and nationwide surveys show 67% of mothers say their children either dislike or hate the taste of liquid medications. FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 3
  • 4. Special C onsiderations While it may seem the child is being difficult, this rejection is rarely the result of a child’s desire to be picky or fussy. Rather, it is an actual physical inability to swallow an unpalatable substance. Children have a greater number of taste buds than adults. These taste buds regenerate every two weeks. As with many of the senses, taste becomes altered as a function of the aging process. That explains why most children find certain flavors to be too 'strong' when adults do not. Children, and infants in particular, are most sensitive to bitter and sweet tastes, making them less likely to swallow bitter-tasting medications and also more prone to liking sweeter, fruity flavors. Unfortunately the active ingredients in many medications often taste bitter and/or have a pungent smell. Masking the taste of these medications can often be difficult simply because the innate flavor is so overpowering. FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 4
  • 5. The Unpleasant E xperience Unpleasant tasting medications can result in particularly poor adherence in children. Struggling with or forcing a child to take an unpleasant tasting medication adds additional strain to the already unpleasant state of feeling sick. It can also predispose children to believe that all medications, regardless of taste or smell, are unpleasant, giving them a negative impression of all medicinal treatments. Like most of us, children will resist unpleasant experiences. FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 5
  • 6. C hildren Taking C harge Not surprisingly, children embrace pleasant experiences including pleasant tastes. Studies have shown that allowing a child to play an active role in choosing the flavor of their medication makes him/her more compliant to drug regimens. Showing a child that they have the capability to modify the flavor of a medication to a flavor of their liking grants them some authority in their treatment. Flavoring not only helps mask the unpleasant taste of a medication but also customizes the medication to satisfy the individual child’s taste preferences. Allowing them to choose how their medication will taste encourages a child to take charge of their own health and is yet another way to promote adherence . FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 6
  • 7. Flavoring C an Help! The addition of a safe pharmaceutical flavoring to medicine can greatly improve a child's sensations of taste and smell, leading to acceptance and therefore compliance. In fact, studies show that proper flavoring can increase compliance in children from 53% to over 90%. As a pharmacist, simply recommend FLAVORx when dispensing a child's medication. The process is scientifically-proven, safe and effective. Unlike the addition of food or drink, FLAVORx flavoring available at the pharmacy will not adversely affect a medicine's stability, efficacy, or potency. FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 7
  • 8. The Importance of A dherence Oftentimes a parent's frustration with giving a bad tasting medication will cause them to stop treatment as soon as their child’s symptoms go away, thus not completing the full course of medication as prescribed by their physician. This is a classic example of poor treatment adherence. Adherence means adhering to or following one’s treatment plan as specified by a physician. Essentially, obeying medical advice. That means taking the correct dose of your medication at the correct time, for the correct duration, and exactly as prescribed. Adherence is very important for successful health outcomes. Conversely, non-adherence can lead to: continued disease processes, health complications, hospitalization, additional doctor visits, therapeutic drug changes, spread of illness, slower recovery, and absenteeism to name a few. FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 8
  • 9. Taste and C hoice Medications successfully taken because of flavoring are far less physically, emotionally, and financially exhausting. For children, taste and choice may be the only motivation to take a medication and complete a full treatment program. Improving the taste of a medication and allowing children a choice as to how their medication will taste can improve therapy adherence, leading to both improved clinical and economic outcomes. FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 9
  • 10. You are done! Please write down your code: Pc4577 - fxu FLAVORx Inc, 9475 Gerwig Lane, Columbia, MD 21046 | 800.884.5771 | www.flavorx.com 10