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CENTRAL AND PERIPHERAL 
NERVOUS SYSTEM
Anatomical division of nervous system 
• Central nervous system (CNS) 
• Consist of brain located in cranial cavity and spinal card 
located in vertebral canal. 
• CNS is responsible for integrating, processing , and 
coordinating sensory data, and giving appropriate 
motor command. 
• It is also the seat of higher functions such as 
intelligence, memory, learning and emotions.
• Peripherar nervous system (PNS) includes all 
the neural tissues outside the CNS , such as 12 
pairs of cranial nerves, 31 pairs of spinal 
nerves and plexus, ganglia associated with 
cranial, spinal nerves and autonomic ganglia. 
• The PNS provides sensory information to the 
CNS and carries its motor commands to the 
peripheral tissues and systems.
C5-T1 
L1-L4
Functional division 
• Afferent brings sensory information to the CNS 
• Efferent carries motor commands to the muscles 
and glands. 
 somatic nervous system (SNS) it provides the 
voluntary control over the skeletal muscle 
contraction 
 autonomic nervous system (ANS) innervates 
involuntary structures such as heart, smooth 
muscle and glands and thus provides an 
involuntary regulation of smooth muscle, 
cardiac muscle, and glandular activity
Central nervous system 
Brain and spinal card 
• Both of them consist of gray matter and white matter 
• In brain the gray matter consist of nerve cell bodies and dendrites 
and present at the periphery,while white matter is made up 
predominantly of myelinated nerve fibres present in the centre. 
• In spinal cord the white matter is outside and gray matter in side. 
• Both grey and white matter contain neuroglia(supporting cells) and 
blood vessels
Brain 
• The adult brain constitutes about one-fiftieth (1/50) of body 
weight(2%of body wt) and weighs about 1400g in male(to 
accommodate more body mass and muscle group) and 1200g in 
female. 
• Neurons=100 billion, uses 20% of body energy, 20% ardiac out 
put,25% of total body glucose, low gluse leeds to coma 
• It consist of following parts 
1. Cerebrum 
2. Diencephalon 
3. Medbrain 
4. Pons 
5. Medulla oblongata 
6. Cerebellum 
Brain stem
A. Prosencephalon –forebrain (1,2) 
-telecephalon:- cerebral hemispheres + lateral ventricles 
Foramen of monro 
- diencephalon:- -thalamus + 3rd ventricle 
-hypothalamus 
- optic cup 
-pituitary 
-pineal body 
B. Mesencephalon: midbrain (3,4) aqueduct of sylvius 
C. Rhombencephalon: hind brain 
- metencephalon – pons(5), cerebellum 
-Myelencephalon- medulla oblongata (6-12) + 4th ventricle 
F. Luschka 
F. magendie 
-central canal 
-subarachnoid space
Functions of the brain 
• It receives information from, and controls the activities of 
trunk and limbs mainly through its connections with the 
spinal cord. 
• It receives the information from, and controls the activities 
of head and neck structures though cranial nerves 
• It assimilates experiences, a requisite to higher mental 
processes such as memory, learning and intelligence 
• It is also responsible for one’s personality, thoughts and 
aspirations.
Cerebrum 
• Consists of two hemispheres left and right, 
occupy the anterior and middle cranial fossae, 
and supratentorial region of posterior cranial 
fossa. 
• The two hemispheres are separated by 
longitudinal cerebral fissure, the fibres of 
corpus callosum interconnect the 
corresponding cortical areas of the two cerebral 
hemispheres, and lies in the floor of cerebral 
fissure. 
• The surface of cerebral hemisphere is 
convoluted, have elevations(gyri) and shallow 
depressions (sulci)
Cerebrum (cont) 
• The central sulcus runs downwards and forwards from superomedial 
border to the lateral sulcus. 
• The superolateral surface of each cerebral hemisphere is divided into 
four lobes, which are named after the overlying skull bones. 
• Frontal lobe: is anterior to the central sulcus, is important for voluntary motor functions, 
motivation, aggression, emotions, effect, drive and awareness of self. 
• Parietl lobe is posterior to the sulcus , is the major center for reception and evaluation of all 
sensory information except for smell hearing, and visions 
• Occipital lobe is behind the parieto-occipital sulcus, is responsible for occupation and 
integration of visual input 
• Temporal lobe is below the lateral sulcus , receives and evaluates input for smell and 
hearing and plays an important role in memory
Cerebrum (cont) 
• Limbic system / lobe is a 
complex ring-shape 
mass of grey matter 
situated at the junction 
of telencephalon and 
diencephalon. 
• It consisting of cingulate 
gyrus, isthmus 
parahippocampal gyrus, 
uncus, dentate gyrus 
• It is associated with basic 
survival instincts, viz. 
acquisition of food and 
water and reproduction 
(sexual behaviour)
Cerebrum (cont) 
• Basal Ganglia is subcortical 
masses of gray matter which are 
situated in the white core of each 
cerebral hemisphere 
• It include the lentiform nucleus, 
caudate nucleus, claustrum, and 
amygdaloid body (these also 
called extraphramidal nuclei. 
• It regulate the muscle tone and 
helps in smoothening the 
voluntary motor activities of the 
body. 
• It control automatic associated 
movements, like swinging of 
arms during walking 
• Control reflex muscular activity 
• Its lesion cause parkinsonism
Diencephalon 
Part of the brain between 
cerebrum and brain stem 
Thalamus is the Largest part of 
the diencephalon, thalamus in 
each hemisphere are separated 
from one another by 3rd 
ventricle 
• Functions: it forms a great 
gate-way for all sensory 
impulses except smell, crude 
sensations like pain and 
touch. 
• It project sensation to the 
cerebral cortex
Hypothalamus: 
• it is the inferior portion of 
diencephalon, which forms 
the floor and inferolateral 
wall of the third ventricle. 
Grossly it is about 4.0 gm 
• It componints are optic 
chiasma, infundibulum, 
tubercinereum and 
mammillary bodies 
• it contains several small 
nuclei and nerve tracts. 
• It regulate visceral activity 
through autonomic nervous 
system and hormonal 
activity through the 
hypothesis cerebri
• Metathalmus: 
• it consist of of 
two medial 7 
lateral geniculate 
bodies, 
• function’s as 
relay stations for 
auditory and 
visual impulses
Epithalamus 
• situated posterior to the 
thalamus,consist of pineal 
body and habenular nuclei. 
• Pineal body is endocrine 
gland,secretes 
melatonin,regulate 
development of 
gonades,secondry sexual 
characters.reduction of 
malatonin secretion 
precipitate puberty 
• Habenular nuclei have 
olfactory and limbic 
connections,influenced by 
smell and involved by 
emotional and visceral 
response
Subthelamus: 
• it lies between 
thalamus and 
midbrain 
• it is involved 
controlling motor 
function(inhibitor 
y control on basal 
nuclei and 
cerebral motor 
cortex
Mid Brain 
• Is the small part of brain stem, is just superior to the pons and contain the 
nuclei 3rd and 4th cranial nerves. It is traversed by the cerebral aqueduct. 
• The part dorsal to the aqueduct, is called tectum, which consist of two 
superior and two inferior colliculi, which in turn concerned with visual and 
auditory reflexes 
• Cerebral peduncles are ventral to the aqueduct,each consist of 
tegmentum,substantia nigra,crus cerebri.space between the two crus 
cerebri is called interpeduncular fossa 
• Function: are ocular reflexes , postural reflexes .contain sensory and motor 
tracts to and from cerebral cortex, basal nuclei 
cerebellum,thalamus,spinal cord 
• 
• Contain 3rd ,4th cranial nuclei
Hind brain 
Pons 
cerebellum 
medulla oblongata
Pons 
• Middle Part of the brain stem. 
• Pons mean bridge, it connect two 
cerebellar hemispheres by middle 
cerebellar peduncles 
• The verticle median sulcus lodges 
basilar artery 
• Dorsal part (tegmentum) is the 
direct upward continuation of 
medulla oblongata(reticular 
formation) contain motor and 
sensory nuclei of 5th cr n. 
• Function= contain vital centres 
(circulatory,respiratory)
Medulla oblongata 
• Lower part of brain stem, continuous 
inferiorly with spinal cord at foramen 
magnum 
• On the ventral surface have two 
pyramidal shaped elevations produced by 
cortico- spinal tracts involved in 
conscious control of skeletal muscles 
• Lateral to pyramids oval elevations called 
inferior olivary nuclei 
• Dorsal to each olive is an inferior 
cerebellar peduncle 
• On the dorsal aspect have cuneate and 
gracile tubercles,containg similarly 
named nuclei 
• Medulla contains various vital autonomic 
centres responsible for several reflexes 
such as thiose involved in regulation of 
heart rate,blood vessels 
diameter,breathing,swallowing 
,vomiting,coughing,sneezing
Cerebellum (little brain) 
• Lies dorsal to pons 
&medulla.consist of 2 
hemispheres and median 
worm like part vermis 
• Connected with mid-brain by 
superior cerebellar 
peduncle,with pons by 
middle cerebellar 
peduncle,with medulla by 
inferior cerebellar peducle 
• Surface has narrow 
transverse ridges called 
folia(leaf) separated by 
fissures 
• Function= involuntry control 
of somatic motor 
activities(maintenace of 
equilibrium,muscle tone,and 
posture)

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Central and peripheral nervous system

  • 1. CENTRAL AND PERIPHERAL NERVOUS SYSTEM
  • 2. Anatomical division of nervous system • Central nervous system (CNS) • Consist of brain located in cranial cavity and spinal card located in vertebral canal. • CNS is responsible for integrating, processing , and coordinating sensory data, and giving appropriate motor command. • It is also the seat of higher functions such as intelligence, memory, learning and emotions.
  • 3. • Peripherar nervous system (PNS) includes all the neural tissues outside the CNS , such as 12 pairs of cranial nerves, 31 pairs of spinal nerves and plexus, ganglia associated with cranial, spinal nerves and autonomic ganglia. • The PNS provides sensory information to the CNS and carries its motor commands to the peripheral tissues and systems.
  • 5. Functional division • Afferent brings sensory information to the CNS • Efferent carries motor commands to the muscles and glands.  somatic nervous system (SNS) it provides the voluntary control over the skeletal muscle contraction  autonomic nervous system (ANS) innervates involuntary structures such as heart, smooth muscle and glands and thus provides an involuntary regulation of smooth muscle, cardiac muscle, and glandular activity
  • 6. Central nervous system Brain and spinal card • Both of them consist of gray matter and white matter • In brain the gray matter consist of nerve cell bodies and dendrites and present at the periphery,while white matter is made up predominantly of myelinated nerve fibres present in the centre. • In spinal cord the white matter is outside and gray matter in side. • Both grey and white matter contain neuroglia(supporting cells) and blood vessels
  • 7. Brain • The adult brain constitutes about one-fiftieth (1/50) of body weight(2%of body wt) and weighs about 1400g in male(to accommodate more body mass and muscle group) and 1200g in female. • Neurons=100 billion, uses 20% of body energy, 20% ardiac out put,25% of total body glucose, low gluse leeds to coma • It consist of following parts 1. Cerebrum 2. Diencephalon 3. Medbrain 4. Pons 5. Medulla oblongata 6. Cerebellum Brain stem
  • 8. A. Prosencephalon –forebrain (1,2) -telecephalon:- cerebral hemispheres + lateral ventricles Foramen of monro - diencephalon:- -thalamus + 3rd ventricle -hypothalamus - optic cup -pituitary -pineal body B. Mesencephalon: midbrain (3,4) aqueduct of sylvius C. Rhombencephalon: hind brain - metencephalon – pons(5), cerebellum -Myelencephalon- medulla oblongata (6-12) + 4th ventricle F. Luschka F. magendie -central canal -subarachnoid space
  • 9.
  • 10. Functions of the brain • It receives information from, and controls the activities of trunk and limbs mainly through its connections with the spinal cord. • It receives the information from, and controls the activities of head and neck structures though cranial nerves • It assimilates experiences, a requisite to higher mental processes such as memory, learning and intelligence • It is also responsible for one’s personality, thoughts and aspirations.
  • 11. Cerebrum • Consists of two hemispheres left and right, occupy the anterior and middle cranial fossae, and supratentorial region of posterior cranial fossa. • The two hemispheres are separated by longitudinal cerebral fissure, the fibres of corpus callosum interconnect the corresponding cortical areas of the two cerebral hemispheres, and lies in the floor of cerebral fissure. • The surface of cerebral hemisphere is convoluted, have elevations(gyri) and shallow depressions (sulci)
  • 12.
  • 13.
  • 14.
  • 15. Cerebrum (cont) • The central sulcus runs downwards and forwards from superomedial border to the lateral sulcus. • The superolateral surface of each cerebral hemisphere is divided into four lobes, which are named after the overlying skull bones. • Frontal lobe: is anterior to the central sulcus, is important for voluntary motor functions, motivation, aggression, emotions, effect, drive and awareness of self. • Parietl lobe is posterior to the sulcus , is the major center for reception and evaluation of all sensory information except for smell hearing, and visions • Occipital lobe is behind the parieto-occipital sulcus, is responsible for occupation and integration of visual input • Temporal lobe is below the lateral sulcus , receives and evaluates input for smell and hearing and plays an important role in memory
  • 16. Cerebrum (cont) • Limbic system / lobe is a complex ring-shape mass of grey matter situated at the junction of telencephalon and diencephalon. • It consisting of cingulate gyrus, isthmus parahippocampal gyrus, uncus, dentate gyrus • It is associated with basic survival instincts, viz. acquisition of food and water and reproduction (sexual behaviour)
  • 17. Cerebrum (cont) • Basal Ganglia is subcortical masses of gray matter which are situated in the white core of each cerebral hemisphere • It include the lentiform nucleus, caudate nucleus, claustrum, and amygdaloid body (these also called extraphramidal nuclei. • It regulate the muscle tone and helps in smoothening the voluntary motor activities of the body. • It control automatic associated movements, like swinging of arms during walking • Control reflex muscular activity • Its lesion cause parkinsonism
  • 18.
  • 19.
  • 20.
  • 21. Diencephalon Part of the brain between cerebrum and brain stem Thalamus is the Largest part of the diencephalon, thalamus in each hemisphere are separated from one another by 3rd ventricle • Functions: it forms a great gate-way for all sensory impulses except smell, crude sensations like pain and touch. • It project sensation to the cerebral cortex
  • 22.
  • 23.
  • 24. Hypothalamus: • it is the inferior portion of diencephalon, which forms the floor and inferolateral wall of the third ventricle. Grossly it is about 4.0 gm • It componints are optic chiasma, infundibulum, tubercinereum and mammillary bodies • it contains several small nuclei and nerve tracts. • It regulate visceral activity through autonomic nervous system and hormonal activity through the hypothesis cerebri
  • 25. • Metathalmus: • it consist of of two medial 7 lateral geniculate bodies, • function’s as relay stations for auditory and visual impulses
  • 26. Epithalamus • situated posterior to the thalamus,consist of pineal body and habenular nuclei. • Pineal body is endocrine gland,secretes melatonin,regulate development of gonades,secondry sexual characters.reduction of malatonin secretion precipitate puberty • Habenular nuclei have olfactory and limbic connections,influenced by smell and involved by emotional and visceral response
  • 27.
  • 28. Subthelamus: • it lies between thalamus and midbrain • it is involved controlling motor function(inhibitor y control on basal nuclei and cerebral motor cortex
  • 29. Mid Brain • Is the small part of brain stem, is just superior to the pons and contain the nuclei 3rd and 4th cranial nerves. It is traversed by the cerebral aqueduct. • The part dorsal to the aqueduct, is called tectum, which consist of two superior and two inferior colliculi, which in turn concerned with visual and auditory reflexes • Cerebral peduncles are ventral to the aqueduct,each consist of tegmentum,substantia nigra,crus cerebri.space between the two crus cerebri is called interpeduncular fossa • Function: are ocular reflexes , postural reflexes .contain sensory and motor tracts to and from cerebral cortex, basal nuclei cerebellum,thalamus,spinal cord • • Contain 3rd ,4th cranial nuclei
  • 30.
  • 31. Hind brain Pons cerebellum medulla oblongata
  • 32. Pons • Middle Part of the brain stem. • Pons mean bridge, it connect two cerebellar hemispheres by middle cerebellar peduncles • The verticle median sulcus lodges basilar artery • Dorsal part (tegmentum) is the direct upward continuation of medulla oblongata(reticular formation) contain motor and sensory nuclei of 5th cr n. • Function= contain vital centres (circulatory,respiratory)
  • 33. Medulla oblongata • Lower part of brain stem, continuous inferiorly with spinal cord at foramen magnum • On the ventral surface have two pyramidal shaped elevations produced by cortico- spinal tracts involved in conscious control of skeletal muscles • Lateral to pyramids oval elevations called inferior olivary nuclei • Dorsal to each olive is an inferior cerebellar peduncle • On the dorsal aspect have cuneate and gracile tubercles,containg similarly named nuclei • Medulla contains various vital autonomic centres responsible for several reflexes such as thiose involved in regulation of heart rate,blood vessels diameter,breathing,swallowing ,vomiting,coughing,sneezing
  • 34.
  • 35. Cerebellum (little brain) • Lies dorsal to pons &medulla.consist of 2 hemispheres and median worm like part vermis • Connected with mid-brain by superior cerebellar peduncle,with pons by middle cerebellar peduncle,with medulla by inferior cerebellar peducle • Surface has narrow transverse ridges called folia(leaf) separated by fissures • Function= involuntry control of somatic motor activities(maintenace of equilibrium,muscle tone,and posture)