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Tooth abnormality in systemic disease

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Tooth abnormality in systemic disease

  1. 1. Tooth abnormality in systemic disease
  2. 2. CONTENTS Syndromes Developmental disturbance in tooth structure Systemic cause of intrinsic staining Abnormality related to medication Medical causes Psychological causes Bone pathology
  3. 3. Syndromes Ectodermal dysplasia Down syndrome Ehlers Danlo syndrome Syndromic craniosynstoses Tricho-Dento-Oseus syndrome
  4. 4. Syndromes
  5. 5. Developmental disturbance in tooth structure
  6. 6. Inherited and acquired chronic diseases • Epidermolysis bullosa • Coeliac disease
  7. 7. Inherited and acquired chronic diseases •Rickets Bone disease of children demineralization and defective bone growth
  8. 8. Inherited and acquired chronic diseases • X-linked hypophosphatemia (PHEX)
  9. 9. Inherited and acquired chronic diseases • X-linked hypophosphatasia (TNSALP)
  10. 10. Systemic cause of intrinsic staining
  11. 11. Systemic cause of intrinsic staining • Neonatal jaundice • Porphyria • Alkaptonuria
  12. 12. Abnormality related to medication
  13. 13. Abnormality related to medication • Tetracycline • Minocycline hydrochloride • Cytotoxic chemotherapy
  14. 14. Medical causes
  15. 15. Other Medical causes • Diabetes • Gastroesophageal reflux
  16. 16. Gastro- esophageal reflux
  17. 17. Psychological causes
  18. 18. Psychological causes • Bulimia and anorexia • Drugs abuse
  19. 19. Bulimia and anorexia
  20. 20. Bone pathology
  21. 21. Bone pathology • Ewing's sarcoma • Histiocytosis X • pseudotumor of haemophilia
  22. 22. References • Burgess, J. (2015) ‘Oral Manifestations of Systemic Disease’, Ada Cerp, pp. 1–12. • Hunter, K. D. and Brierley, D. (2017) ‘Pathology of the teeth: an update’, Diagnostic Histopathology. Elsevier Ltd, 23(6), pp. 275–283. doi: 10.1016/j.mpdhp.2017.04.005. • Sharma, U. and Bhalla, S. (2010) ‘Oral manifestations of a systemic disease.’, American Family Physician, 82, pp. 1381–1388. doi: 10.1016/S0733-8635(02)00066-9. • Regezi, J., 2012. Oral Pathology clinical pathological correlation. 6th ed. Missoury: Elsevier.

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