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Anesthesia Monitoring
     Sarah Ouellette CVT.
Anesthesia and Monitoring
Goals:
  Provide a stage of reversible unconsciousness
    with adequate analgesia and muscle relaxation
    for surgical procedures that dose not jeopardize
    the animals health.


   Identify problems early institute treatment
    promptly and avoid irreversible adverse outcomes
Why we monitor?
 Anesthetic emergencies/complications:
   Difficult to predict
   Happen quickly
   Become life threatening quickly


 It is better to be proactive than reactive
 Prevention is key!
Monitoring
Remember:
 No monitoring device can
  take the place of constant
  human observation


 The equipment we use only
  enhances our ability to
  monitor a patient
Monitoring
 Starts when animal is dropped off
   Pre-anesthetic evaluation
     includes History, Physical Exam




 Ends after recovery period
   even day after
Pre-anesthetic Evaluation
 History: what you want to know
 Individual risk factors/underling problems
   Age – certain risks for pediatric and geriatric patients
   Breed – brachiocephalic (long recovery)
   Temperament – aggressive/fractious (pre-med early)



 Physical Exam – TPR, heart murmurs, lung sounds
 Procedure – invasiveness, pain level
Stages of Anesthesia
 Stage 1: Pre-medication


 Stage 2: Induction


 Stage 3: Maintenance
   Planes: 1 – 4



 Stage 4: Recovery
Stages
1. Pre-medication:
 IV or IM injection – sedation/pain relief
   Tranquilizer: no pain relief
     ex: midazolam, acepromazine, diazepam

   Add opioid for pain relief:
     ex: hydromorphone, fentanyl, buprenex, morphine

   +/- anticholinergic: help maintain HR
     ex. atropine, glycopyrrolate
Stages
 Pre-medication:
   Decreases need for increased induction agents
    and inhalant anesthetics
   Aids for smoother induction and recovery


   Place IV catheter during this stage
   May start fluids or pain management CRI at this
    time
Stage 1: Pre-medication
What we monitor:
 Heart rate
 Respiratory rate
 Perfusion – MM color/CRT
 Pulses
 Drooling/vomiting
 Level of sedation
 Reactions to medications
Stages
2. Induction:
 Use Injectable anesthetics to yield an
       unconscious state
     Ex: Ketamine, Propofol

 Can be masked down with inhalant anesthetic
     Not recommended


 Induction agents are given to facilitate intubation prior to
being placed on an inhalant agent for maintenance
Stage 2: Induction
What we monitor:
 HR/RR
 Perfusion - MM color/CRT
 Pulses
 CNS reflex's – depth
Stages
3. Maintenance:
 Unconscious + pain free
 Inhalant anesthetic used to maintain unconsciousness
   Ex. Isoflurane, sevoflurane
 Procedure is performed
   +/- IV fluids
   +/- Pain management CRI (fentanyl, MKL)
     Procedure dependant
Stage 3: Maintenance
What we monitor:
 HR/RR
 Perfusion - MM color/CRT
 Pulses
 CO2/O2 concentrations
 Blood Pressure
 CNS reflex's – depth
 Temperature
Stages
4. Recovery:
 Good = uneventful
 Inhalant turned off  Extubated
 Vitals monitored until awake/ambulatory
   every 5 – 10 min
 Ideally warm quiet area


 One of the most important stages of anesthesia
  morbidity is higher in this stage than any others
Stage 4: Recovery
What we monitor:
 HR/RR
 Perfusion – MM color/CRT
 Pulses
 Temperature
 CNS signs – consciousness
 +/- Blood pressure
Planes of Anesthesia
 Planes are used to describe depth of anesthesia during
  the maintenance stage



 Plane 1: light
 Plane 2: medium
 Plane 3: deep
 Plane 4: too deep
Planes of Anesthesia
Plane 1 (light):
 Regular HR
 +/- irregular RR
 Swallowing reflex decreases
 Limb movements decrease
 CNS signs present
 Pain sensitive
 Considerable jaw tone
Planes of Anesthesia
Plane 2 (medium):
 Suitable for procedures
 HR + RR reactive to stimulus  unconscious
 3rd eyelid may rotate up
 Skeletal muscle relaxes
 Absence limb movements
 CNS signs decrease
 Jaw tone decreases
 Normal blood pressure
Planes of Anesthesia
Plane 3 (Deep):
 Decrease HR + RR even with stimulus
 May need ventilation
 Pulses weaken
 Blood pressure drops
 CRT prolonged
 No jaw tone or CNS signs
Planes of anesthesia
Plane 4 (too deep):
 Significant decrease HR
 Erratic jerky rest rate or apnea
 No CNS signs
 Pale gums – prolonged CRT
 BP too low to read
 Can be permanently damaging
What is an ideal depth?
 Procedure dependent
 Patient dependent
 Good analgesia without depressing HR or RR
 Low as possible vapor setting
 IV analgesics safer (less detrimental effects) than
  increasing vapor setting but more difficult to adjust
  the depth
Monitoring
 Parameters we monitor during anesthesia:

1. Central nervous system
2. Cardiovascular system
3. Respiratory system
4. Temperature
Monitoring CNS
 Varies spp to spp and patient to patient
 Good indication of DEPTH of anesthesia
 CNS signs are called reflexes
 Monitor multiple reflexes


 Increase in anesthetic depth = a decrease of reflexes
Common CNS reflexes
Eye position:
 Pupils begin in central position  Then move
  rostroventral in an adequate plane  Then
  move BACK central as the patient moves into a
  deeper plane
  More Effective in dogs

 Ineffective if animal has received a dissociative
  drug
   Ex. Ketamine - eyes are fixed centrally
Eye Positioning
Common CNS reflexes
Palpebral reflex:
 Touch medial or lateral canthus of the eye or
  eyelashes
 Looking for a blink response
 Weak/absent = adequate plane
 May become desensitized if over tested
CNS common reflexes
Pupil constriction/dilation:
• Induction – slt dilated or normal
• Maintenance:
      Plane 1+2 can constrict
      Planes 3+4 = more and more dilated



• Cats: unreliable if received atropine  Dilated pupils
Common CNS reflexes
Nystagmus:
 Involuntary rapid movement of eyeball
 Move side/side, up/down, rotary
 Can happen in an excitement phase– common in
  animals that are masked down or given certain
  drugs
 Important reflex in recovery period:
   Can be seen in dysphoric patients – common if given an opioid
   Patients become light and sound sensitive
Common CNS reflexes
Swallowing:
• Spontaneous when awake
• Lost plane 1
• Regains after consciousness
• Important in recovery stage
  • Must be present before extubation to prevent
     aspiration
CNS common reflexes
Laryngeal reflex:
 Monitored during intubation
 Arytenoids close to protect trachea
 Elicited by tube stimulation
 Induction decreases this reflex
   Lost plane 1
   Cats may need deeper plane to avoid laryngospasms
Larynx/Arytenoids




 DO NOT TOUCH ARYTENOIDS
   Can cause laryngospasms
Common CNS reflexes
Cough reflex:
 Monitored during intubation

 Normal response in awake animals

 Intact until plane 2


 Common reflex in cats during recovery stage
   When extubation is warranted
CNS common reflexes
Pedal reflex:
• Pinching digit or pad looking for withdrawal
• Lost by plane 2
• Movement = inadequate depth for surgery
• Shouldn’t be present with inhalant anesthesia
CNS common reflexes
Ear/whisker reflex:
• Touch inner surface of pinna or whiskers
  •   Looking for twitch response

• Present = inadequate depth for surgery
• Lost by plane 2
• May become desensitized → tested too often
CNS common reflexes
Muscle tone:
 Present in light to medium planes
 Jaw Tone:
   Opening jaw – estimate amount of resistance
   Want some resistance
   Flaccid jaw often indicative of excessive depth
   Less reliable in pediatric patients

 Anal Tone:
   less reliable
   If present = too light for surgical stimulus
CNS common reflexes
Response to surgical stimulus:
 Movement
    Lost by plane 2


 Dramatic increase in HR and RR

 Late indicator of inadequate depth
Monitoring Circulation
Goal:


 Ensure adequate blood flow to tissues and
  vital organs
How we monitor Circulation
 Heart rate


 Blood pressure


 Tissue perfusion
Monitoring HR
Heart rate:
     Base rate (resting rate)
     Breed, weight, age, fitness level play factor to base rate
     because of this it is difficult to define universal ranges for all
    patients

Normal:
•   Dogs: 70 – 180 bpm

•   Cats: 140 – 200 bpm

•    Pediatric patients: dog 150-180bpm, cat 150-210bpm
    • They need a higher rate to maintain cardiac output
Monitoring HR
Bradycardia: Low HR
   < 60 dogs
   < 120 cats


Common causes:
 Drugs/inhalants (have depressant effect)
   If patient is too deep
Monitoring HR
Tachycardia: High HR
   > 180 dogs
   > 220 cats


Common causes:
  Pain
  Drugs
    Ex. Atropine, gycopyrrolate, ketamine
Monitoring HR
How we monitor heart rate:

1. Palpation

2. Auscultation

3. Pulse Oximeter

4. Electrocardiogram (ECG)
Monitoring HR
Palpation of chest for heart rate:
   Difficult to feel
   Less reliable


Palpation of peripheral artery:
    Femoral, metacarpal, dorsal pedal, cranial tibial,
   lingual most common
    Count a rate
    Note the quality – normal, bounding, weak
Common
Palpable
Arteries
Monitoring HR
Auscultation of the heart:

• Hand held stethoscope
  • Count rate
  • Detect murmurs
Monitoring HR
Esophageal stethoscope:
 Tube passed down esophagus connected to
  earpieces – creates an audible sound
 Tip should be level with heart
 Do not to pass into the stomach  reflux/regurg
 Note Rate and Rhythm


 Can also hear respiratory rate and note character
Esophageal Stethoscopes
Monitoring HR
Pulse Oximeter:
 Gives pulse rate
 As well as SpO2 concentration
 Machine detects pulsation from
  external probe and formats into
  a numerical value



 Has become a standard of care in veterinary medicine
Monitoring HR
Electrocardiography (ECG):
 Shows electrical activity (cardiac cells)
 Important for detecting arrhythmias
 Also gives heart rate


DOES NOT give information about mechanical function of heart
(shouldn't be sole method for heart monitoring)
   A deceased animal may still have electrical activity of the heart but no
     actual beat
Monitoring HR
Electrocardiography (ECG)
 Has 4 leads (most have 3): placed on armpit and flank

          : Right front
   Black: Left front
   Red: Left hind
   Green: Right hind*
 * this lead is commonly left out
Monitoring HR
ECG Leads:
 Need Good contact for proper function
 Ultrasound gel VS. Alcohol as a conductor
 Studies say ultrasound gel is better because:
 Alcohol evaporates quickly and you need to reapply for
  longer procedures
   It also cools as is evaporates  cause hypothermia
ECG leads
Monitoring HR
Electrocardiograph: waveform
 Provides regional information about the heart
   P wave
   QRS complex
   T wave
 Each letter represents a location and function of heart


 Abnormal waveform called arrhythmia
Monitoring HR
Common causes of arrhythmias:
 Heart dz #1
 Pain
 Drugs - (atropine and glycopyrrolate)
 Electrolyte imbalances
 Poor oxygenation
ECG Rhythms
 Normal:
Abnormal ECG Rhythms
 Atrioventricular Block (AV block)




 Absence of QRS complex and T wave (dropped beat)
Abnormal ECG Rhythms
 Ventricular Premature Contractions (VPC’s)




      Extra beat originating from from ventricles
Monitoring Blood Pressure
Blood Pressure:
 Force of the flow of blood on vessel walls
   measured in mmHg



Goal:
 Maintain adequate blood flow and O2 delivery to
  tissues and vital organs
Monitoring Blood Pressure
Further defined:

 Systolic pressure – SAP

 Diastolic Pressure – DAP

 Mean Pressure – MAP
Monitoring Blood Pressure
Normal ranges under anesthesia:
   Systolic
     80-150mmHg

   Diastolic
     40-80mmHg

   Mean - More important/accurate parameter
     Dogs: 60-100mmHg
     Cats: 60-120mmhg
Monitoring Blood Pressure
Hypotension: low blood pressure
 MAP < 60mmHg
   Tissue perfusion is compromised

 Common complication under anesthesia
   Drugs/inhalants depressant


 Tx/prevent: Lower inhalant, start fluids – give boluses,
  certain drugs
Monitoring Blood Pressure
Hypertension: high blood pressure
 MAP > 175mmHg


Causes:

 Underling Heart disease
 Pain
Monitoring Blood Pressure
Dependent on:
 Volume blood entering heart (before contraction)
 Ability of heart to contract (muscle function)
 Heart rate
 Resistance to forward blood flow (vessel size)
 Viscosity of blood
Monitoring Blood Pressure
How we monitor BP:
1. Oscillometric technique
2. Doppler technique
3. Arterial technique*
4. Central Venous Pressure technique*


* More common in critical patients not commonly used
Monitoring Blood Pressure
Oscillometric technique:
 Indirect method – non-invasive
 Cuff placed around major artery
   automatically inflated
 Transducer within cuff detects pressure changes within
  artery
 Records pulsations
 Transmits # to screen
Monitoring Blood Pressure
Oscillometric technique:
   Gives Mean, systolic, and diastolic parameters


 SurgiVet monitor: labeled as NIBP
 Data states systolic pressure is less accurate in this
  device
 HOWEVER the mean value tends to be more accurate
   (mean is the more important value)
Monitoring Blood Pressure
 Oscillometric technique:
Monitoring Blood Pressure
Doppler:
 Indirect method
 non-invasive


**ONLY used to
measure SAP**
Monitoring Blood Pressure
Pressure Cuff: both techniques
 Need uniform compression of artery
 Size cuff relative to limb being compressed
 Width cuff should be 40% of the circumference limb
 Cats can be 30-40%
 Too small cuff = higher values
 Too big cuff = low values
Monitoring Blood Pressure
Arterial monitoring: (gold standard)
 Yields most accurate results
 Direct method – Invasive method
 IVC placed in dorsal pedal or metacarpal ARTERIES
   Need a highly skilled technician
   Risks of infection and hemorrhage are high

   Because of these reasons it is not common technique
Monitoring Blood Pressure
Arterial monitoring:
 Catheter connected to electronic pressure transducer
  via extension tubing and transmits signal to monitor

 Displays: SAP, DAP, MAP and constant waveform
Arterial Catheter
Arterial Catheter
Monitoring Blood Pressure
 Central Venous Pressure
  Reflects volume capacity of the right side of heart
   and amount of blood returning to the heart
  Helpful in assessing fluid status (hydration)
  Need: jugular catheter

  Normal range:
    0-5 cmH2O (trends more important than individual
     numbers)
Monitoring Tissue Perfusion
How we monitor tissue perfusion:
1. Palpation Artery


2. Mucus membrane color


3. Capillary refill time
Monitoring Tissue perfusion
Palpation of peripheral artery:
   Femoral, metacarpal, dorsal pedal, cranial tibial,
  lingual commonly used
   Note the quality – normal, bounding, weak
     Weak pulses = circulatory insufficiency


   Monitored in conjunction with HR
     pulse should be synchronous with heart rate
     Every beat should have a pulse (pulse deficit)
Monitoring Tissue perfusion
Mucus membrane color:
 Should be pink and moist
 Abnormal:
   Pale = vasoconstriction, blood loss or anemia
   Purple or blue = cyanosis
   Dry/sticky = dehydrated (dugs)
   Red/injected = heat stroke, sepsis, carbon
    monoxide poisoning
   Yellow (icteric) = liver disease
Mucus Membrane Colors
                        Pale



 Normal




                    Cyanotic
Icteric
Monitoring Tissue Perfusion
Capillary refill time:
 Touch gums note time it takes for color to return
   should be < 2 sec

 Prolonged = poor perfusion
Respiration
Goal:

 Move O2 into the lungs and expel CO2 out


 Ensure adequate O2 and CO2 concentrations
  in blood
Physiology of Respiration
 O2 in arterial blood is carried to tissues  normal
  metabolism occurs  CO2 byproduct or metabolism
   the CO2 is diverted into venous blood taken to
  heart  travels to lungs  capillaries in lungs 
  CO2 transferred into alveolar sacs in lungs and
  expelled out  O2 transferred from alveolar sacs
  into arterial capillaries  travels back to the heart 
  pumped into systemic circulation  tissues
Then repeat!
Anatomy of Respiration
   Alveolar sac:
Blue –
venous
blood from
body high
levels of
CO2

Red –
arterial blood
high in O2
going back
to the body
Anatomy of Respiration
Anatomy of Respiration
 Alveoli expand and contract with respirations

 Deep breath into lungs expands more of sacs

 Which increases surface area for exchange:
   CO2 from capillary veins into alveolar sacs
   O2 and anesthetic gas into arterial blood
Monitoring Respiration
 Inhalants are #1 respiratory depressant!


 Increase anesthetic depth = decrease in volume of
  air taken into the lungs (tidal volume)
   Decreases by 25%


 Why?
   Drugs limit expansion of intercostal muscles
     muscles we use to inspire
Monitoring Respiration
 As tidal volume decreases the alveoli collapse
       can decrease the function of lungs

 Treat this by giving breath (bagging) – every 5 min

 Watch the pressure monometer
   Avoid over inflation of lungs
   Never go over 20cmH2O
      15cmH20 smaller patients
Monitoring Respiration
 Varies between patients
 Normal resting rates:
   Dogs 10 – 20
   Cats 15 – 25


 Under anesthesia:
   8-20 both spp.
Monitoring Respiration
Causes of decrease in respiration:
 Drugs we give
 Too deep
 Heavy drapes or instruments on small patients
 Dr. hand over patients chest
 Low CO2 concentration
Monitoring Respiration
Causes of increase respiration:
 Surgical stimulation
 Too light/pain
 Lung disease
   Pulmonary edema, pneumothorax, masses, ect.
Monitoring Respiration
How we monitor respiration/ventilation:

1. Visual/listening

2. Monitoring CO2

3. Monitoring O2
Monitoring Respiration
Visual/listening:
 Observe chest movements

 Watch breathing bag

 Handheld stethoscope

 Listen to breathing sounds with esophageal stethoscope
   gives rate and quality
Monitoring CO2
Respiratory Rate:
 Can correlate to amount of CO2 in blood
   Normal Value: 35-45 mmHG


 To high (>50) can stimulate respiration (receptors in
  brain signal lungs to breath to eliminate the excess
  Co2)
   dependent on anesthetic depth, drugs, etc.

 To low (<30) apnea or shallow breathing
Monitoring CO2
How we monitor CO2:

1. Blood Gas Analysis


2. Capnography
Monitoring CO2
Blood Gas: “GOLD STANDARD”
 Most accurate determinant of CO2 levels in blood
 Direct – invasive method
 Need:
     Arterial blood sample
     Blood gas analyzer
     Skilled technician
     Patient dependent – size, age

                   **Not common method**
Monitoring CO2
However…

 Measuring end tidal CO2 (EtCO2) using
  capnography is useful alternative to estimate levels
  in blood (PaCO2) without invasive techniques
Monitoring CO2
Capnography:
 Indirect – non-invasive method
 Become most common method
 Numerical +/- graphical display
 Estimation of CO2 in arterial blood by the
  concentration of CO2 that is exhaled
Monitoring Oxygenation
CapnoGRAPH tells us:
    Graphical display CO2 that is exhaled
    EtCO2 concentration
    Resp rate


CapnoMETER tells us:
    EtCO2 concentration
    Resp rate
Capnography



                      Capnograph




Capnometer
Monitoring Oxygenation
Capnograph:
Monitoring CO2
Why is capnoGRAPH preferred?


 Graphical display useful for determining:
   Airway obstruction
   Leak in endotracheal tube
Normal Capnograph
 Graphical display
Abnormal Capnograph




 Inadequately inflated endotracheal tube cuff
 Damaged or leaking endotracheal tube cuff
Abnormal Capnograph




 Obstruction of endotracheal tube
   Blood or mucus buildup
   Kinked tube
Monitoring CO2
CO2 exchange is linked to:
1. Perfusion (blood flow) to capillaries in tissue and lungs
2. Ventilation (exchange alveoli sacs)
3. Metabolism (production of CO2)


      ** Keep in mind all of these factors when looking at

                  the values on the monitors**
Monitoring O2
SpO2:
 Measures level of arterial O2 in saturated hemoglobin
   hemoglobin in RBC is the O2 carrying component in blood



 Gives us an estimation of oxygenation
 Helps us to determine need for O2 supplementation
 SpO2 should be > than 95%
   98-100% under anesthesia
Monitoring O2
O2 exchange is linked to:
1. Perfusion (blood flow) in tissues and lungs
    Any factor that inhibits blood flow can affect
      these results

2. Ventilation (exchange alveoli sacs)
Monitoring O2
How we monitor O2:


1. Blood Gas Analysis


2. Pulse Oximeter
Monitoring O2
Blood Gas: “GOLD STANDARD”
 Most accurate determinant of O2 levels in blood
 Direct – invasive method
 Need:
     Arterial blood sample
     Need blood gas analyzer
     Skilled technician
     Patient dependant – size, age


                    *Not commonly used*
Monitoring SpO2
Pulse Oximitry:
 Non-invasive – indirect method
 Two red light wavelengths pass through body tissue
 O2 rich blood blocks less red light than oxygen depleted
  blood

 Separates parameters and gives a numerical % of O2
  saturation

 Also gives us a Heart rate
Pulse Oximeter machines
Pulse Oximetry
 Surgi-Vet Monitor
Monitoring SpO2
Probes:
 Tongue – most common in anesthetized patients
 Can be placed on lip, ear, inguinal skin fold, toe web, tail, skin
   along achilles tendon, prepuce or vulva


 If placed on ear/lip red light should be inside facing out


 Light should face down
    to avoid risk of ambient light  can lead to falsely increased values
Pulse Oximetry
 Probes
Pulse Ox equipment
Rectal probe:
 Rectum must be free of excess foreign material
 Light positioned dorsally
 Anchor it to the tail with tape
Monitoring SpO2
Causes of low readings:
 Pigmented skin
 Tissue thickness
 Anemic animals
 Poor perfusion
   Check mm color and CRT for abnormal readings
 Tylenol toxicities (destroys hemoglobin)


 Reposition probe (every 5 - 10 min)
    Probe itself can occlude vessels and decrease results
Monitoring SpO2
High readings:
 Falsely increased
 Florescent lights
   Place drape or towel over probe

 Important to check other parameters too!
   MM/CRT
   **if an animal has pale gums but a high SpO2 you may need
                         to troubleshoot**
Temperature
Goal:


 Maintain a body temperature adequate for normal
  metabolic functions


 Avoid accidental hypothermia or malignant
  hyperthermia
Temperature
Normal:
 99.5 – 102.5F




 Hypothermia: low temp
 Hyperthermia: high temp
Monitoring temperature
Hypothermia:
 Common complication under anesthesia
 Loose heat rapidly
   First 20 minutes most loss
 Stay above 98 degrees for not to be detrimental to patient
 Dramatically slows anesthetic recovery
 Monitor every 15 – 30 min, as well as post-op until normal
Monitoring Temperature
Why they get so cold?
 Shave fur
 Scrub with fluids that cool as they evaporate
 Take away their inability to shiver
 Open body cavity to room air
 Drugs/inhalants
Monitoring Temperature
Treating hypothermia:
 Prevention. Prevention. Prevention
 Warm IVF
 Hot water pads/blankets
 Bubble wrap feet
 Warm blankets
 Bair huggers
Monitoring Temperature
Treating hypothermia:
 Hot water bottles/fluid bags in towels
        ** NEVER direct contact with patient**
            heat + pressure + time = necrosis
Monitoring Temperature
Causes of hyperthermia:
 Excessive application of heat in attempt to prevent
  hypothermia

 Infections
 Cats – adverse reaction to hydromorphone
 Ketamine
Monitoring temperature
Treating hyperthermia
 Remove blankets from cage
 Place ice packs in towels in cage
   Not directly on the patient

       ** REMEMBER: if methods are being used to treat
   hyperthermia, the temperature should be monitored closely
             to prevent subsequent hypothermia **
How We Monitor Temperature

 Manually – hand thermometer


 Esophageal probe


 Rectal probe
Thermometer probes
Record Keeping

 How we keep it all together
Record keeping
Goal:


 Maintain a legal record of significant events during
  the anesthetic period


 Recognize trends or unusual values or parameters
  and allow assessment of response to intervention
Record Keeping
Useful for 4 main reasons:
1. See trends in patient vitals  address problems
2. Archive record to compare similar cases (statistical
   analysis)

3. Reference for anesthesia in future
4. Legal document so it needs to be complete and easy to
   read
Record Keeping
Anesthesia record/sheet should have:
 Patient ID
 Procedure
 Pre-op findings
 Drugs given – dose, time, route
 Pre-op TPR
 Vitals – 5 min during procedure
 Unusual circumstances – arrhythmias, drug reactions,
  regurgitation ect.
 O2 and inhalant anesthetic rates
Record Keeping
 Types of anesthesia sheets


1. Graphical


2. Numerical
 Graphical
 Numerical
In Conclusion
 No SINGLE criteria tells you how an animal is handling
  anesthesia

 Add up vitals and reflexes to determine a safe
  anesthetic depth

 Make sure anesthetic procedure is properly documented
 NEVER be afraid to ask a Dr. or another technician
 The only dumb question is the one not asked!

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Anesthesia monitoring bulger

  • 1. Anesthesia Monitoring Sarah Ouellette CVT.
  • 2. Anesthesia and Monitoring Goals:  Provide a stage of reversible unconsciousness with adequate analgesia and muscle relaxation for surgical procedures that dose not jeopardize the animals health.  Identify problems early institute treatment promptly and avoid irreversible adverse outcomes
  • 3. Why we monitor?  Anesthetic emergencies/complications:  Difficult to predict  Happen quickly  Become life threatening quickly  It is better to be proactive than reactive  Prevention is key!
  • 4. Monitoring Remember:  No monitoring device can take the place of constant human observation  The equipment we use only enhances our ability to monitor a patient
  • 5. Monitoring  Starts when animal is dropped off  Pre-anesthetic evaluation  includes History, Physical Exam  Ends after recovery period  even day after
  • 6. Pre-anesthetic Evaluation  History: what you want to know  Individual risk factors/underling problems  Age – certain risks for pediatric and geriatric patients  Breed – brachiocephalic (long recovery)  Temperament – aggressive/fractious (pre-med early)  Physical Exam – TPR, heart murmurs, lung sounds  Procedure – invasiveness, pain level
  • 7. Stages of Anesthesia  Stage 1: Pre-medication  Stage 2: Induction  Stage 3: Maintenance  Planes: 1 – 4  Stage 4: Recovery
  • 8. Stages 1. Pre-medication:  IV or IM injection – sedation/pain relief  Tranquilizer: no pain relief  ex: midazolam, acepromazine, diazepam  Add opioid for pain relief:  ex: hydromorphone, fentanyl, buprenex, morphine  +/- anticholinergic: help maintain HR  ex. atropine, glycopyrrolate
  • 9. Stages  Pre-medication:  Decreases need for increased induction agents and inhalant anesthetics  Aids for smoother induction and recovery  Place IV catheter during this stage  May start fluids or pain management CRI at this time
  • 10. Stage 1: Pre-medication What we monitor:  Heart rate  Respiratory rate  Perfusion – MM color/CRT  Pulses  Drooling/vomiting  Level of sedation  Reactions to medications
  • 11. Stages 2. Induction:  Use Injectable anesthetics to yield an unconscious state  Ex: Ketamine, Propofol  Can be masked down with inhalant anesthetic  Not recommended  Induction agents are given to facilitate intubation prior to being placed on an inhalant agent for maintenance
  • 12. Stage 2: Induction What we monitor:  HR/RR  Perfusion - MM color/CRT  Pulses  CNS reflex's – depth
  • 13. Stages 3. Maintenance:  Unconscious + pain free  Inhalant anesthetic used to maintain unconsciousness  Ex. Isoflurane, sevoflurane  Procedure is performed  +/- IV fluids  +/- Pain management CRI (fentanyl, MKL)  Procedure dependant
  • 14. Stage 3: Maintenance What we monitor:  HR/RR  Perfusion - MM color/CRT  Pulses  CO2/O2 concentrations  Blood Pressure  CNS reflex's – depth  Temperature
  • 15. Stages 4. Recovery:  Good = uneventful  Inhalant turned off  Extubated  Vitals monitored until awake/ambulatory  every 5 – 10 min  Ideally warm quiet area  One of the most important stages of anesthesia morbidity is higher in this stage than any others
  • 16. Stage 4: Recovery What we monitor:  HR/RR  Perfusion – MM color/CRT  Pulses  Temperature  CNS signs – consciousness  +/- Blood pressure
  • 17. Planes of Anesthesia  Planes are used to describe depth of anesthesia during the maintenance stage  Plane 1: light  Plane 2: medium  Plane 3: deep  Plane 4: too deep
  • 18. Planes of Anesthesia Plane 1 (light):  Regular HR  +/- irregular RR  Swallowing reflex decreases  Limb movements decrease  CNS signs present  Pain sensitive  Considerable jaw tone
  • 19. Planes of Anesthesia Plane 2 (medium):  Suitable for procedures  HR + RR reactive to stimulus  unconscious  3rd eyelid may rotate up  Skeletal muscle relaxes  Absence limb movements  CNS signs decrease  Jaw tone decreases  Normal blood pressure
  • 20. Planes of Anesthesia Plane 3 (Deep):  Decrease HR + RR even with stimulus  May need ventilation  Pulses weaken  Blood pressure drops  CRT prolonged  No jaw tone or CNS signs
  • 21. Planes of anesthesia Plane 4 (too deep):  Significant decrease HR  Erratic jerky rest rate or apnea  No CNS signs  Pale gums – prolonged CRT  BP too low to read  Can be permanently damaging
  • 22. What is an ideal depth?  Procedure dependent  Patient dependent  Good analgesia without depressing HR or RR  Low as possible vapor setting  IV analgesics safer (less detrimental effects) than increasing vapor setting but more difficult to adjust the depth
  • 23. Monitoring  Parameters we monitor during anesthesia: 1. Central nervous system 2. Cardiovascular system 3. Respiratory system 4. Temperature
  • 24. Monitoring CNS  Varies spp to spp and patient to patient  Good indication of DEPTH of anesthesia  CNS signs are called reflexes  Monitor multiple reflexes  Increase in anesthetic depth = a decrease of reflexes
  • 25. Common CNS reflexes Eye position:  Pupils begin in central position  Then move rostroventral in an adequate plane  Then move BACK central as the patient moves into a deeper plane  More Effective in dogs  Ineffective if animal has received a dissociative drug  Ex. Ketamine - eyes are fixed centrally
  • 27. Common CNS reflexes Palpebral reflex:  Touch medial or lateral canthus of the eye or eyelashes  Looking for a blink response  Weak/absent = adequate plane  May become desensitized if over tested
  • 28. CNS common reflexes Pupil constriction/dilation: • Induction – slt dilated or normal • Maintenance:  Plane 1+2 can constrict  Planes 3+4 = more and more dilated • Cats: unreliable if received atropine  Dilated pupils
  • 29. Common CNS reflexes Nystagmus:  Involuntary rapid movement of eyeball  Move side/side, up/down, rotary  Can happen in an excitement phase– common in animals that are masked down or given certain drugs  Important reflex in recovery period:  Can be seen in dysphoric patients – common if given an opioid  Patients become light and sound sensitive
  • 30. Common CNS reflexes Swallowing: • Spontaneous when awake • Lost plane 1 • Regains after consciousness • Important in recovery stage • Must be present before extubation to prevent aspiration
  • 31. CNS common reflexes Laryngeal reflex:  Monitored during intubation  Arytenoids close to protect trachea  Elicited by tube stimulation  Induction decreases this reflex  Lost plane 1  Cats may need deeper plane to avoid laryngospasms
  • 32. Larynx/Arytenoids DO NOT TOUCH ARYTENOIDS Can cause laryngospasms
  • 33. Common CNS reflexes Cough reflex:  Monitored during intubation  Normal response in awake animals  Intact until plane 2  Common reflex in cats during recovery stage  When extubation is warranted
  • 34. CNS common reflexes Pedal reflex: • Pinching digit or pad looking for withdrawal • Lost by plane 2 • Movement = inadequate depth for surgery • Shouldn’t be present with inhalant anesthesia
  • 35. CNS common reflexes Ear/whisker reflex: • Touch inner surface of pinna or whiskers • Looking for twitch response • Present = inadequate depth for surgery • Lost by plane 2 • May become desensitized → tested too often
  • 36. CNS common reflexes Muscle tone:  Present in light to medium planes  Jaw Tone:  Opening jaw – estimate amount of resistance  Want some resistance  Flaccid jaw often indicative of excessive depth  Less reliable in pediatric patients  Anal Tone:  less reliable  If present = too light for surgical stimulus
  • 37. CNS common reflexes Response to surgical stimulus:  Movement  Lost by plane 2  Dramatic increase in HR and RR  Late indicator of inadequate depth
  • 38. Monitoring Circulation Goal:  Ensure adequate blood flow to tissues and vital organs
  • 39. How we monitor Circulation  Heart rate  Blood pressure  Tissue perfusion
  • 40. Monitoring HR Heart rate:  Base rate (resting rate)  Breed, weight, age, fitness level play factor to base rate  because of this it is difficult to define universal ranges for all patients Normal: • Dogs: 70 – 180 bpm • Cats: 140 – 200 bpm • Pediatric patients: dog 150-180bpm, cat 150-210bpm • They need a higher rate to maintain cardiac output
  • 41. Monitoring HR Bradycardia: Low HR  < 60 dogs  < 120 cats Common causes:  Drugs/inhalants (have depressant effect)  If patient is too deep
  • 42. Monitoring HR Tachycardia: High HR  > 180 dogs  > 220 cats Common causes:  Pain  Drugs  Ex. Atropine, gycopyrrolate, ketamine
  • 43. Monitoring HR How we monitor heart rate: 1. Palpation 2. Auscultation 3. Pulse Oximeter 4. Electrocardiogram (ECG)
  • 44. Monitoring HR Palpation of chest for heart rate:  Difficult to feel  Less reliable Palpation of peripheral artery:  Femoral, metacarpal, dorsal pedal, cranial tibial, lingual most common  Count a rate  Note the quality – normal, bounding, weak
  • 46. Monitoring HR Auscultation of the heart: • Hand held stethoscope • Count rate • Detect murmurs
  • 47. Monitoring HR Esophageal stethoscope:  Tube passed down esophagus connected to earpieces – creates an audible sound  Tip should be level with heart  Do not to pass into the stomach  reflux/regurg  Note Rate and Rhythm  Can also hear respiratory rate and note character
  • 49. Monitoring HR Pulse Oximeter:  Gives pulse rate  As well as SpO2 concentration  Machine detects pulsation from external probe and formats into a numerical value  Has become a standard of care in veterinary medicine
  • 50. Monitoring HR Electrocardiography (ECG):  Shows electrical activity (cardiac cells)  Important for detecting arrhythmias  Also gives heart rate DOES NOT give information about mechanical function of heart (shouldn't be sole method for heart monitoring)  A deceased animal may still have electrical activity of the heart but no actual beat
  • 51. Monitoring HR Electrocardiography (ECG)  Has 4 leads (most have 3): placed on armpit and flank : Right front  Black: Left front  Red: Left hind  Green: Right hind*  * this lead is commonly left out
  • 52. Monitoring HR ECG Leads:  Need Good contact for proper function  Ultrasound gel VS. Alcohol as a conductor  Studies say ultrasound gel is better because:  Alcohol evaporates quickly and you need to reapply for longer procedures  It also cools as is evaporates  cause hypothermia
  • 54. Monitoring HR Electrocardiograph: waveform  Provides regional information about the heart  P wave  QRS complex  T wave  Each letter represents a location and function of heart  Abnormal waveform called arrhythmia
  • 55. Monitoring HR Common causes of arrhythmias:  Heart dz #1  Pain  Drugs - (atropine and glycopyrrolate)  Electrolyte imbalances  Poor oxygenation
  • 57. Abnormal ECG Rhythms  Atrioventricular Block (AV block)  Absence of QRS complex and T wave (dropped beat)
  • 58. Abnormal ECG Rhythms  Ventricular Premature Contractions (VPC’s)  Extra beat originating from from ventricles
  • 59. Monitoring Blood Pressure Blood Pressure:  Force of the flow of blood on vessel walls  measured in mmHg Goal:  Maintain adequate blood flow and O2 delivery to tissues and vital organs
  • 60. Monitoring Blood Pressure Further defined:  Systolic pressure – SAP  Diastolic Pressure – DAP  Mean Pressure – MAP
  • 61. Monitoring Blood Pressure Normal ranges under anesthesia:  Systolic  80-150mmHg  Diastolic  40-80mmHg  Mean - More important/accurate parameter  Dogs: 60-100mmHg  Cats: 60-120mmhg
  • 62. Monitoring Blood Pressure Hypotension: low blood pressure  MAP < 60mmHg  Tissue perfusion is compromised  Common complication under anesthesia  Drugs/inhalants depressant  Tx/prevent: Lower inhalant, start fluids – give boluses, certain drugs
  • 63. Monitoring Blood Pressure Hypertension: high blood pressure  MAP > 175mmHg Causes:  Underling Heart disease  Pain
  • 64. Monitoring Blood Pressure Dependent on:  Volume blood entering heart (before contraction)  Ability of heart to contract (muscle function)  Heart rate  Resistance to forward blood flow (vessel size)  Viscosity of blood
  • 65. Monitoring Blood Pressure How we monitor BP: 1. Oscillometric technique 2. Doppler technique 3. Arterial technique* 4. Central Venous Pressure technique* * More common in critical patients not commonly used
  • 66. Monitoring Blood Pressure Oscillometric technique:  Indirect method – non-invasive  Cuff placed around major artery  automatically inflated  Transducer within cuff detects pressure changes within artery  Records pulsations  Transmits # to screen
  • 67. Monitoring Blood Pressure Oscillometric technique:  Gives Mean, systolic, and diastolic parameters  SurgiVet monitor: labeled as NIBP  Data states systolic pressure is less accurate in this device  HOWEVER the mean value tends to be more accurate  (mean is the more important value)
  • 68. Monitoring Blood Pressure  Oscillometric technique:
  • 69. Monitoring Blood Pressure Doppler:  Indirect method  non-invasive **ONLY used to measure SAP**
  • 70. Monitoring Blood Pressure Pressure Cuff: both techniques  Need uniform compression of artery  Size cuff relative to limb being compressed  Width cuff should be 40% of the circumference limb  Cats can be 30-40%  Too small cuff = higher values  Too big cuff = low values
  • 71. Monitoring Blood Pressure Arterial monitoring: (gold standard)  Yields most accurate results  Direct method – Invasive method  IVC placed in dorsal pedal or metacarpal ARTERIES  Need a highly skilled technician  Risks of infection and hemorrhage are high  Because of these reasons it is not common technique
  • 72. Monitoring Blood Pressure Arterial monitoring:  Catheter connected to electronic pressure transducer via extension tubing and transmits signal to monitor  Displays: SAP, DAP, MAP and constant waveform
  • 75. Monitoring Blood Pressure  Central Venous Pressure  Reflects volume capacity of the right side of heart and amount of blood returning to the heart  Helpful in assessing fluid status (hydration)  Need: jugular catheter  Normal range:  0-5 cmH2O (trends more important than individual numbers)
  • 76. Monitoring Tissue Perfusion How we monitor tissue perfusion: 1. Palpation Artery 2. Mucus membrane color 3. Capillary refill time
  • 77. Monitoring Tissue perfusion Palpation of peripheral artery:  Femoral, metacarpal, dorsal pedal, cranial tibial, lingual commonly used  Note the quality – normal, bounding, weak  Weak pulses = circulatory insufficiency  Monitored in conjunction with HR  pulse should be synchronous with heart rate  Every beat should have a pulse (pulse deficit)
  • 78. Monitoring Tissue perfusion Mucus membrane color:  Should be pink and moist  Abnormal:  Pale = vasoconstriction, blood loss or anemia  Purple or blue = cyanosis  Dry/sticky = dehydrated (dugs)  Red/injected = heat stroke, sepsis, carbon monoxide poisoning  Yellow (icteric) = liver disease
  • 79. Mucus Membrane Colors Pale Normal Cyanotic Icteric
  • 80. Monitoring Tissue Perfusion Capillary refill time:  Touch gums note time it takes for color to return  should be < 2 sec  Prolonged = poor perfusion
  • 81. Respiration Goal:  Move O2 into the lungs and expel CO2 out  Ensure adequate O2 and CO2 concentrations in blood
  • 82. Physiology of Respiration  O2 in arterial blood is carried to tissues  normal metabolism occurs  CO2 byproduct or metabolism  the CO2 is diverted into venous blood taken to heart  travels to lungs  capillaries in lungs  CO2 transferred into alveolar sacs in lungs and expelled out  O2 transferred from alveolar sacs into arterial capillaries  travels back to the heart  pumped into systemic circulation  tissues Then repeat!
  • 83. Anatomy of Respiration  Alveolar sac: Blue – venous blood from body high levels of CO2 Red – arterial blood high in O2 going back to the body
  • 85. Anatomy of Respiration  Alveoli expand and contract with respirations  Deep breath into lungs expands more of sacs  Which increases surface area for exchange:  CO2 from capillary veins into alveolar sacs  O2 and anesthetic gas into arterial blood
  • 86. Monitoring Respiration  Inhalants are #1 respiratory depressant!  Increase anesthetic depth = decrease in volume of air taken into the lungs (tidal volume)  Decreases by 25%  Why?  Drugs limit expansion of intercostal muscles  muscles we use to inspire
  • 87. Monitoring Respiration  As tidal volume decreases the alveoli collapse  can decrease the function of lungs  Treat this by giving breath (bagging) – every 5 min  Watch the pressure monometer  Avoid over inflation of lungs  Never go over 20cmH2O  15cmH20 smaller patients
  • 88. Monitoring Respiration  Varies between patients  Normal resting rates:  Dogs 10 – 20  Cats 15 – 25  Under anesthesia:  8-20 both spp.
  • 89. Monitoring Respiration Causes of decrease in respiration:  Drugs we give  Too deep  Heavy drapes or instruments on small patients  Dr. hand over patients chest  Low CO2 concentration
  • 90. Monitoring Respiration Causes of increase respiration:  Surgical stimulation  Too light/pain  Lung disease  Pulmonary edema, pneumothorax, masses, ect.
  • 91. Monitoring Respiration How we monitor respiration/ventilation: 1. Visual/listening 2. Monitoring CO2 3. Monitoring O2
  • 92. Monitoring Respiration Visual/listening:  Observe chest movements  Watch breathing bag  Handheld stethoscope  Listen to breathing sounds with esophageal stethoscope  gives rate and quality
  • 93. Monitoring CO2 Respiratory Rate:  Can correlate to amount of CO2 in blood  Normal Value: 35-45 mmHG  To high (>50) can stimulate respiration (receptors in brain signal lungs to breath to eliminate the excess Co2)  dependent on anesthetic depth, drugs, etc.  To low (<30) apnea or shallow breathing
  • 94. Monitoring CO2 How we monitor CO2: 1. Blood Gas Analysis 2. Capnography
  • 95. Monitoring CO2 Blood Gas: “GOLD STANDARD”  Most accurate determinant of CO2 levels in blood  Direct – invasive method  Need:  Arterial blood sample  Blood gas analyzer  Skilled technician  Patient dependent – size, age **Not common method**
  • 96. Monitoring CO2 However…  Measuring end tidal CO2 (EtCO2) using capnography is useful alternative to estimate levels in blood (PaCO2) without invasive techniques
  • 97. Monitoring CO2 Capnography:  Indirect – non-invasive method  Become most common method  Numerical +/- graphical display  Estimation of CO2 in arterial blood by the concentration of CO2 that is exhaled
  • 98. Monitoring Oxygenation CapnoGRAPH tells us:  Graphical display CO2 that is exhaled  EtCO2 concentration  Resp rate CapnoMETER tells us:  EtCO2 concentration  Resp rate
  • 99. Capnography Capnograph Capnometer
  • 101. Monitoring CO2 Why is capnoGRAPH preferred?  Graphical display useful for determining:  Airway obstruction  Leak in endotracheal tube
  • 103. Abnormal Capnograph  Inadequately inflated endotracheal tube cuff  Damaged or leaking endotracheal tube cuff
  • 104. Abnormal Capnograph  Obstruction of endotracheal tube  Blood or mucus buildup  Kinked tube
  • 105. Monitoring CO2 CO2 exchange is linked to: 1. Perfusion (blood flow) to capillaries in tissue and lungs 2. Ventilation (exchange alveoli sacs) 3. Metabolism (production of CO2) ** Keep in mind all of these factors when looking at the values on the monitors**
  • 106. Monitoring O2 SpO2:  Measures level of arterial O2 in saturated hemoglobin  hemoglobin in RBC is the O2 carrying component in blood  Gives us an estimation of oxygenation  Helps us to determine need for O2 supplementation  SpO2 should be > than 95%  98-100% under anesthesia
  • 107. Monitoring O2 O2 exchange is linked to: 1. Perfusion (blood flow) in tissues and lungs  Any factor that inhibits blood flow can affect these results 2. Ventilation (exchange alveoli sacs)
  • 108. Monitoring O2 How we monitor O2: 1. Blood Gas Analysis 2. Pulse Oximeter
  • 109. Monitoring O2 Blood Gas: “GOLD STANDARD”  Most accurate determinant of O2 levels in blood  Direct – invasive method  Need:  Arterial blood sample  Need blood gas analyzer  Skilled technician  Patient dependant – size, age *Not commonly used*
  • 110. Monitoring SpO2 Pulse Oximitry:  Non-invasive – indirect method  Two red light wavelengths pass through body tissue  O2 rich blood blocks less red light than oxygen depleted blood  Separates parameters and gives a numerical % of O2 saturation  Also gives us a Heart rate
  • 113. Monitoring SpO2 Probes:  Tongue – most common in anesthetized patients  Can be placed on lip, ear, inguinal skin fold, toe web, tail, skin along achilles tendon, prepuce or vulva  If placed on ear/lip red light should be inside facing out  Light should face down  to avoid risk of ambient light  can lead to falsely increased values
  • 115. Pulse Ox equipment Rectal probe:  Rectum must be free of excess foreign material  Light positioned dorsally  Anchor it to the tail with tape
  • 116. Monitoring SpO2 Causes of low readings:  Pigmented skin  Tissue thickness  Anemic animals  Poor perfusion  Check mm color and CRT for abnormal readings  Tylenol toxicities (destroys hemoglobin)  Reposition probe (every 5 - 10 min)  Probe itself can occlude vessels and decrease results
  • 117. Monitoring SpO2 High readings:  Falsely increased  Florescent lights  Place drape or towel over probe  Important to check other parameters too!  MM/CRT **if an animal has pale gums but a high SpO2 you may need to troubleshoot**
  • 118. Temperature Goal:  Maintain a body temperature adequate for normal metabolic functions  Avoid accidental hypothermia or malignant hyperthermia
  • 119. Temperature Normal:  99.5 – 102.5F  Hypothermia: low temp  Hyperthermia: high temp
  • 120. Monitoring temperature Hypothermia:  Common complication under anesthesia  Loose heat rapidly  First 20 minutes most loss  Stay above 98 degrees for not to be detrimental to patient  Dramatically slows anesthetic recovery  Monitor every 15 – 30 min, as well as post-op until normal
  • 121. Monitoring Temperature Why they get so cold?  Shave fur  Scrub with fluids that cool as they evaporate  Take away their inability to shiver  Open body cavity to room air  Drugs/inhalants
  • 122. Monitoring Temperature Treating hypothermia:  Prevention. Prevention. Prevention  Warm IVF  Hot water pads/blankets  Bubble wrap feet  Warm blankets  Bair huggers
  • 123. Monitoring Temperature Treating hypothermia:  Hot water bottles/fluid bags in towels ** NEVER direct contact with patient** heat + pressure + time = necrosis
  • 124. Monitoring Temperature Causes of hyperthermia:  Excessive application of heat in attempt to prevent hypothermia  Infections  Cats – adverse reaction to hydromorphone  Ketamine
  • 125. Monitoring temperature Treating hyperthermia  Remove blankets from cage  Place ice packs in towels in cage  Not directly on the patient ** REMEMBER: if methods are being used to treat hyperthermia, the temperature should be monitored closely to prevent subsequent hypothermia **
  • 126. How We Monitor Temperature  Manually – hand thermometer  Esophageal probe  Rectal probe
  • 128. Record Keeping  How we keep it all together
  • 129. Record keeping Goal:  Maintain a legal record of significant events during the anesthetic period  Recognize trends or unusual values or parameters and allow assessment of response to intervention
  • 130. Record Keeping Useful for 4 main reasons: 1. See trends in patient vitals  address problems 2. Archive record to compare similar cases (statistical analysis) 3. Reference for anesthesia in future 4. Legal document so it needs to be complete and easy to read
  • 131. Record Keeping Anesthesia record/sheet should have:  Patient ID  Procedure  Pre-op findings  Drugs given – dose, time, route  Pre-op TPR  Vitals – 5 min during procedure  Unusual circumstances – arrhythmias, drug reactions, regurgitation ect.  O2 and inhalant anesthetic rates
  • 132. Record Keeping  Types of anesthesia sheets 1. Graphical 2. Numerical
  • 135. In Conclusion  No SINGLE criteria tells you how an animal is handling anesthesia  Add up vitals and reflexes to determine a safe anesthetic depth  Make sure anesthetic procedure is properly documented  NEVER be afraid to ask a Dr. or another technician  The only dumb question is the one not asked!

Hinweis der Redaktion

  1. ** Anesthetized patients