management of Status Epilepticus

1. STATUS EPILEPTICUS
Dr LNR Gonzalez. MD
Kimberley Hospital.2016

2. Status Epilepticus (SE)
Definition
– Generalized,convulsive Status Epilepticus refers
to at least 5 min of
a) Continuous convultions or
b) Two or more convultions between which there are
incomplete recovery of consciousness

6. Midazolam loading dose of 0.2mg/kg (slow IV bolus)up to a
maximum of loading dose of 2mg/kg.
Then at a dose of 0.1mg/kg/h(range: 0.05 mg/kg–2.9 mg/kg per
hr)
Propofol at a dose of 1-2mg/kg IV
Followed by 2-10mg/kg hourly

7. Side Effects of Drugs
• Apnea
• Arrhythmia
• Sedation
• Hypotension
• Lose Protective Reflexes

8. Complications
• Pyrexia
• Fluid and electrolyte abnormalities
• Dysglycemia
• Renal failure
• Hypoxia
• Drugs

9. Once Patient Condition Stabilized
• Complete History and Neurological
Examination
• CT Scan/MRI
• Lumbar puncture
• EEG
– Diagnosis
– Assessing adequacy of treatment
• Long term Treatment

10. • KHC Department of Internal medicine – protocol for the
management of SE. 2010.
• Guidelines for the Evaluation and Management of Status
Epilepticus. Neurocrit Care 2012.
• Grand Rounds: An Update on Convulsive Status Epilepticus.
The Ulster Medical Society, 2015.
• Evidence-Based Guideline: Treatment of Convulsive Status
Epilepticus in Children and Adults: Report of the Guideline
Committee of the American Epilepsy Society. Epilepsy Currents,
Vol. 16, No. 1 (January/February) 2016 pp. 48–61.
References

11. THE END