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ANORECTAL CANCER – Symptoms and Signs Louise Fischer Med IV
But first, some basic anatomy
Anorectal cancer – what the? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Definitions according to WHO and AJCC (American Joint Committee on Cancer) ,[object Object],[object Object]
Anal canal cancer ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Anal Canal Cancer (cont) ,[object Object],[object Object],[object Object],[object Object]
Anal Margin Cancer ,[object Object],[object Object]
Anal Margin Cancer (cont) On physical examination, an erythematous, eczematoid rash is apparent.  When grossly apparent, lesions appear scaly, discrete, erythematous, and sometimes pigmented.  Lesions appear with raised, irregular edges and central ulceration.  Large, centrally ulcerated lesions with rolled everted edges.  Feels hard and woody on palpation. Signs Characteristically severe intractable pruritus. Perianal burning / itching /pain Bleeding / itching / pain Mass / bleeding / pain / discharge / itching / tenesmus  Symptoms Paget’s Disease Bowen’s Disease Basal cell carcinoma Squamous Cell Carcinoma
Rectal Cancer ,[object Object],[object Object],[object Object],[object Object],[object Object]
Rectal cancer (cont) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rectal cancer (cont)
Rectal cancer (cont) ,[object Object],1 in 2 Autosomal dominant pedigree 1 in 6 2x 1 st -degree relatives affected 1 in 10 1x 1 st -degree relative affected (age<45) 1 in 12 1x 1 st -degree relative + 1x 2 nd -degree relative affected 1 in 17 1x 1 st -degree relative affected (any age) 1 in 50 Population risk
Rectal cancer (cont) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rectal cancer (cont) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rectal cancer (cont) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rectal cancer - symptoms ,[object Object],[object Object]
Rectal cancer - symptoms 1% Liver metastasis 3% Peritonitis from perforation 5% Pelvic pain 9% Bowel obstruction 9% Other: Malaise 20% Abdominal pain 26% Occult bleeding 43% Change in bowel habits 60% Bleeding
Rectal cancer - symptoms ,[object Object],[object Object],[object Object],[object Object]
Rectal cancer - symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object]
Rectal cancer - symptoms ,[object Object],[object Object],[object Object],[object Object]
Rectal cancer - signs ,[object Object],[object Object],[object Object],[object Object],[object Object]
List of resources ,[object Object],[object Object],[object Object],[object Object],[object Object]

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1. Anorectal Cancer Symptoms And Signs

  • 1. ANORECTAL CANCER – Symptoms and Signs Louise Fischer Med IV
  • 2. But first, some basic anatomy
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  • 8. Anal Margin Cancer (cont) On physical examination, an erythematous, eczematoid rash is apparent. When grossly apparent, lesions appear scaly, discrete, erythematous, and sometimes pigmented. Lesions appear with raised, irregular edges and central ulceration. Large, centrally ulcerated lesions with rolled everted edges. Feels hard and woody on palpation. Signs Characteristically severe intractable pruritus. Perianal burning / itching /pain Bleeding / itching / pain Mass / bleeding / pain / discharge / itching / tenesmus Symptoms Paget’s Disease Bowen’s Disease Basal cell carcinoma Squamous Cell Carcinoma
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  • 17. Rectal cancer - symptoms 1% Liver metastasis 3% Peritonitis from perforation 5% Pelvic pain 9% Bowel obstruction 9% Other: Malaise 20% Abdominal pain 26% Occult bleeding 43% Change in bowel habits 60% Bleeding
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