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Laboratory LOINC Workshop – Indianapolis, IN	




               LOINC	
                 Introduction and Overview	

           Daniel J. Vreeman, PT, DPT, MSc	
               Assistant Research Professor, Indiana University School of Medicine	
                           Research Scientist, Regenstrief Institute, Inc	




12.08.2011	
                dvreeman@regenstrief.org	
                                 © 2011
http://loinc.org/slideshows
Origins of LOINC	
The lingua franca of clinical observation exchange
Regenstrief’s 40+ Years of
Canopy Computing	
making a forest out of individual trees of data	



 McDonald et al. Canopy Computing: using the Web in Clinical Practice. JAMA. 1998;280(15):1325-1329.
photo via nosha
Arboreal Informatics Pioneers	
 40 years of EMR work	
 Indiana Network for Patient Care	
      	
	
 Nation’s most comprehensive and longest tenured HIE	


 Regenstrief 	
 – the neutral 3rd party convener
Fundamental challenge:	
local systems have
idiosyncratic ways of
identifying similar concepts
Vocabulary standards
provide the linuga franca.
Logical
           Observation
           Identifiers
           Names and
           Codes	
A universal code system that facilitates exchange,
        pooling, and processing of results
Similar name, different meaning…	




                                            photo via Caption Time	


 meerkat	
 meerkat	
 mere cat	
 meerkat
If an observation is a question
and the observation value is
an answer…

  	
LOINC provides codes for
   	
questions

   	
Other vocabularies provide
   	
codes for the answers
What is my patient’s
hemoglobin level?	
718-7:Hemoglobin:MCnc:Pt:Bld:Qn
How fast does my
patient usually walk?	
41959-8:Walking speed:Vel:1W^mean:^Patient:Qn:Calculated
Indiana Network for Patient Care	
   HL7 v.2.X Message	
MSH|^~&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay|||||||||||||||
PID|||$patientId$||$patientName$||||||||||||||||||||
     LocalCode^LocalName^CodeSystem^LOINCcode^LOINCname^CodeSystem
PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||
OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate|||||||||
OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F|
OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F|
OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F|
OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|




          A	
  




                        Message Processor	
                       A	
  



                                                     Institutional Repository
Result with a Coded Value	

      Data type of
   result (OBX-5) is a       This code is              This code is
    coded element	
          from LOINC	
            from SNOMED	


OBX||CE|57131-5^Newborn conditions with pos markers^LN||7573000^PKU^SCT



 Code identifying this
     observation 	
(what are these results?                   Code identifying the
Conditions identified by                  result (Phenylketonuria )	
  newborn screening )
A brief aside about
terminology…	


                      photo via eye of einstein
LOINC Terminology	
  LOINC (noun)	
From “Standardizing the MDS with LOINC® and Vocabulary Matches”
  Tohttp://aspe.hhs.gov/daltcp/reports/2007/MDS-LOINC.htm
      LOINC, LOINCing, LOINCed (verb)	
  [Chief, Head, etc] LOINCer (noun)	
  LOINCification (noun)	
  	
  SNOMED Terminology	
  	
  SNOMED (noun)	
  SNOMEDicated???
Different standards for different
parts of the elephant.	




                        photo via Ludovic Hirlimann
SNOMED CT	
Systematized Nomenclature of Medicine - Clinical Terms	




                                                           photo via Bruce McKay~YSP
LOINC + SNOMED?
International Classification of
Diseases (ICD)	
and the rest of the family	




                                 photo via Esparta
RxNorm	
normalized names for clinical drugs	




                                        photo via e-MagineArt.com
We now return to our
           regularly scheduled
           program…	




photo via x-ray delta one
Laboratory LOINC
Clinical LOINC
The LOINC Community	
Open. Nimble. Pragmatic.
Open Development	
Worldwide distribution at no cost	
End-user content additions	
Welcome all comers	
Volunteers
Regenstrief Institute	
Steward	
Developer of content	
Developer of tools	
Developer of community	
Distributor	
Voice
LOINC Codes Over Time By Release	
70,000	
            LOINC Codes	
            Lab Codes	
60,000	
                                            Slope = 2200	
50,000	

                            Slope = 600	
40,000	


30,000	


20,000	


10,000	
                                       laboratory terms only	

      0
16,000	
            loinc.org members	
14,000	


12,000	


10,000	


 8,000	


 6,000	


 4,000	


 2,000	
           14 new members per day	
                 410 new members per month	
      0
14,420+ users in 145 countries
@LOINC
Downloads: ~1400/month
The LOINC Distribution
http://search.loinc.org
http://search.loinc.org
http://forum.loinc.org
loinc.org/usage	




“Top 2000 Results”
a.k.a. “Top 300 Orders”
a.k.a. “Common Units of Measure”
International Adoption	
participation, translation, implementation
LOINC Submitters	




        2009 to April 2011	
84 organizations from 14 countries
LOINC Translators	




   18 organizations
Chinese	
  (CHINA)	
  	
  
Dra$	
  Portuguese	
  (BRAZIL)	
  	
  
English	
  (UNITED	
  STATES)	
  	
  
Estonian	
  (ESTONIA)	
  	
  
French	
  (CANADA)	
  	
  
French	
  (FRANCE)	
  	
  
French	
  (SWITZERLAND)	
  	
  
German	
  (GERMANY)	
  	
  
German	
  (SWITZERLAND)	
  	
  
Greek	
  (GREECE)	
  	
  
Italian	
  (ITALY)	
  	
  
Italian	
  (SWITZERLAND)	
  	
  
Korean	
  (KOREA,	
  REPUBLIC	
  OF)	
  	
  
Spanish	
  (ARGENTINA)	
  	
  
Spanish	
  (SPAIN)	
  	
  
Spanish	
  (SWITZERLAND)	
  	
  
In-progress	
Catalan	
Dutch	
French	
Russian
Large Implementations	
SIGA Saúde project 	
Canada Health Infoway	
ePSOS	
Assistance publique - Hôpitaux de Paris	
Hong Kong Hospital Authority	
Red Agrolab	
BiTAC	
  Lots more…success is often silent
US Adoption	
A few key highlights
US Federal Agencies	
        NLM	
         VA	
        DoD	
        IHS	
        NCI	
        CDC
Other Key US Adoptions	
        HITSP	
        eLINCS	
       NAACCR	
        CDISC	
    NCQA/HEDIS, NQF	
         HL7	
        HIPAA	
         HIE’s
EHR Incentive
   Program
a.k.a. “Meaningful Use”
St a n da rds
^
New Frontiers in
Content Modeling
LOINC Collections	
Panels, forms, surveys, and other patient
assessments	




                                        photo via LuzA
Standardized Assessments	




Vreeman DJ, McDonald CJ, Huff SM. Representing patient assessments in LOINC®. AMIA Annu Symp Proc. 2010;832-836. PMID: 21347095 .	
Vreeman DJ, McDonald CJ, Huff SM. LOINC® - A Universal Catalog of Individual Clinical Observations and Uniform Representation of Enumerated Collections.
     Int J Funct Inform Personal Med. 2010;3(4):273-291.
Purpose	
Assessments are widely used…	




…and not unlike other clinical observations
LOINC could be a
       	
           	
 master question file
          and
uniform representation
Hierarchy of a Panel in LOINC
Panels/Forms Available as
   Separate Download
Sample of Assessments in LOINC	
US Government Forms	
    CARE, MDSv2, MDSv3, OASIS B1, OASIS C, RFC	
    US Surgeon General’s Family Health Portrait	
Brief Interview for Mental Status (BIMS)	
Confusion Assessment Method (CAM)	
Geriatric Depression Scale (GDS)	
HIV Signs and Symptoms Checklist	
Home Health Care Classification	
howRU	
Living with HIV (LIV-HIV)	
Morse Fall Scale	
OMAHA	
PHQ (9 and 2)	
Quality Audit Marker (QAM)
Translational Research Variables	


 11,000+ variables	

        Oh snap!
Lots More Cooking…	
Lots of forms and assessments	
More radiology reports	
Structured document titles	
Genetic testing	
…	
	
	

                                  photo via liber
Key Lessons
for Today	

              photo via IMLS DCC
photo via wakefielddavid	



Not just an IT problem
Get real.	
units, results, experts
Don’t be a
 one hit
 wonder.	

             photo via gsz
A journey. 	
Not a destination.
Clean water act	




                    photo via Fishking_1
photo via milos milosevic
The Race is On!	




 Get LOINCing!	
                    photo via ryarwood

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