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Understanding and Teaching
Students with Anxiety and Depression



Rona Milch Novick, PhD




                                  Rev 1/11
Erica’s Story
Erica is a middle school student, who has always been a
   bit clingy, shy and nervous. This year, during a
   school trip she got sick and threw up on the bus.
   Ever since, she has refused to go on the school bus.
   She will not take gym class, complaining that
   running around makes her feel like she will be sick.
   She refuses to go to school many mornings, and
   spends a lot of time in the nurse’s office, saying she
   thinks she is going to be sick.
Yossi’s Story
Yossi transferred to the all boy’s high school for 10th
  grade saying he wanted a new start. He failed most
  subjects in 9th grade and his parents say he became
  really withdrawn, no longer hanging out with his
  friends. When asked about it he said it’s just not
  fun anymore. He says he hopes the change in school
  will help but doubts it since he is not really good at
  anything and will probably fail. His parents also
  find him more angry and disrespectful, and he seems
  to want to sleep constantly.
Think- Pair- Share
What Does This Have to Do With
School?

   List 3 ways anxiety could interfere with
    school success

   List 3 ways depression could interfere with
    school success
Stress/Anxiety-Performance
Curve
Performance




              Anxiety
Anxiety and Avoidance
Stimulus         Anxiety

                 Avoidance


                  Decreased
                  Anxiety
Components of Anxiety
Triple Response Mode:
 Physiological arousal

 Hypervigilance/worry

 Behavioral avoidance (as a result)
Impacts of Anxiety In School
Settings
   Negatively affects academic work and school
    performance
   Impairments in social adjustment
   Decreased social acceptance
   Low global self worth
   Co-morbidity is significant
     12% depression
     15% oppositional defiant disorder
     17% ADHD
     50-75% another anxiety disorder
Psychiatric difficulties in youth
   American Academy of Pediatrics: 20% of children
    aged 4-15 have psychological or behavioral problems
    (2x increase since 1980)
   Estimates of actual psychiatric disorders:
       12 million American children and teens
       5-15% of 9-10 year olds
       15-20% of adolescents
       Adult comparison: 20%
   Criteria: DSM-IV, including symptom severity and
    impairment in functioning (family school, peers)
Etiology
   Biological disorders of neurotransmitters
   Emergence of disorders precipitated by:
       genetic vulnerability
       deficient social supports
       family dysfunction
       trauma
       chronic environmental stress
How Prevalent Are Anxiety
Disorders?
   Most common psychiatric disorder in
    children
   Estimated 10-20% incidence rate
   Anxiety symptoms are persistent over
    time
   Prognosis poor if untreated
   More common in girls
   Up to 30% of all children may exhibit
    subclinical levels of worry
Anxiety Interventions as
Resilience Builders
   Cognitive Behavioral Interventions
       Cognitive techniques
           Metacognitive lessons on healthy thinking
       Skill building
           Imagery, emotional literacy, other direct skills
       Relaxation training
Negative Thinking Exercise
   With your group of 4, review the common
    negative thought patterns
   Create examples for three of these and,
    without indentifying which type of negative
    thought pattern they are, write them on your
    paper
   Groups will rotate around the room and
    attempt to indentify the negative thought
    pattern in each example
Exercise Debrief
   Pedagogic technique – having students create
    examples increases learning
   “Carousel” often involves movement,
    possibility for non-verbal responding,
    repeated practice
School Involvement in Treatment

    Majority of child’s time is in school
    School is child’s natural environment,
     generalization is essential
    School requires intact cognitive and
     social functioning
    School personnel are central in child’s
     life
Interventions
   Behavioral and
    Cognitive-Behavioral Treatments
       Exposure
       Response Prevention
       Relaxation/Imagery
       Reinforced practice/Operant techniques
       Cognitive Techniques
   Family Treatment
   Psychopharmacology
       Clomipramine
       SSRI’s
Need for Sensitivity:
Role of Schools
   Any and all school personnel can be part of
    solution or problem
   All school personnel must understand disorder
    and students’ needs
   All school personnel should respond sensitively
    and therapeutically
   Communication between school, home and
    outside professionals is essential
Intervention – Helping Those With
Special Needs
   Slow but steady movement
   Avoid avoidance
   Communication across settings
   Reinforcement of learned skills
   Generalization training
Reaction
Handling Anxious Reactions
   Match anxiety with calm
   Prompt for skill use
   Attempt not to go backwards – even if
    forwards is impossible
   View as temporary crisis
   Reinforce non-anxious behavior but use
    caution in penalizing anxious behavior
Anxiety Disorder Diagnoses
   Separation Anxiety Disorder
   Generalized Anxiety Disorder
   Social Phobia
   Selective Mutism
   Obsessive Compulsive Disorder

*School Phobia is not formal diagnosis
Generalized Anxiety Disorder
   Excessive and unrealistic worries
       About competence, approval, future, past
   Extreme self-consciousness
   Excessive need for reassurance
   Inability to relax
   Somatic complaints
       Trouble concentrating
       Sleep disturbance
       Fatigued
   Symptoms for 6 months or more
Separation Anxiety Disorder
Developmentally inappropriate & excessive anxiety concerning
   separation from home or attachment figures, with 3 or more
    recurrent excessive distress at separation
    persistent and excessive worry about losing or harm befalling
      attachment figures
    persistent reluctance or refusal to go to school or elsewhere
    persistent fearfulness at being alone
    persistent reluctance to go to sleep without being near major
      attachment figure
    repeated nightmares about separation
    repeated c/o physical symptoms at separation or when
      anticipated
Separation Anxiety - cont’d
   Duration of at least 4 weeks
   Onset before age 18
   Clinically significant distress
   Not PDD, Schizophrenia, Psychotic
    disorder, or Panic Disorder in adolescents
Selective Mutism
   Rare, fewer than 1% of referrals
   Usually begins in preschool
   Many children reported as shy
School Phobia
   Not a formal diagnosis
   Variant of separation anxiety disorder,
    social phobia or other anxiety disorder
   Rarely actual phobia to school setting
   Distinguish from truancy and school
    refusal
Obsessive Compulsive Disorder
   Presence of obsessions or compulsion
   Obsessions are
       persistent ideas - intrusive
       unable to ignore
   Compulsions are
       repetitive behavior or thought driven to perform in
        response to obsession
       Aimed at preventing distress
   Causes marked distress
   Child knows O/C are unreasonable
Video Watching Guide              (Selective
Mutism)
   What is one thing you heard that you didn’t
    know
   What is one thing you would do differently as
    a result of watching the video
Depression in Children and
Adolescents
   How does depression effect learning?
   How does depression effect testing?
   How does depression effect other aspects of school
    functioning?

   http://www.youtube.com/watch?v=S1PPCzRkBKQ
Depressed mood and depressive
disorders
   Depressed mood relatively common:
       10% school-age children
       40% adolescents
   If persistent and severe:
       Affective disorders, including Major Depressive Disorder,
        Bipolar Disorder, Dysthymic Disorder
   Fewer than 1 in 5 young people who need tx for
    depression get it
Historical trends
   “Parents are too stern, chide, brawl, whip and strike…
    children are so disheartened they never have a merry
    hour in their lives…” (Burton, 1621)
   Depression-like features in children whose
    attachment was not initiated, interrupted, or lost
    (Bowlby, Spitz, A. Freud, ’30s-’60s)
   “Masked depression” (’50s-’70s)
   Mood disorders of youth parallel adults (70s+)
Models of depression – with relevance
for school settings
   Learned helplessness (behavior independent of
    reinforcement)
   http://www.youtube.com/watch?v
    =gFmFOmprTt0
   Cognitive distortions (negative views of self,
    environment and the future)
   Life stress (SES, family factors, poor social supports)
   Genetic/Biochemical (neurotransmitters)
Neurotransmitters
 Serotonin: low levels associated with
  violence, suicidality (decreased CSF
  concentration of 5HIAA)
 Dopamine: increase of dopamine activity
  implicated in psychotic depression
 Norepinephrine: abnormalities found in
  urinary MHPG of depressed patients
Assessment
   Need for multiple respondents
   Clinical interview (structured?)
   Rating scales (CDI, Beck, CBCL, BASC)
   Psychological testing
   Behavior observation
   DSM-IV
Mood disorders
   Major Depressive Disorder
   Dysthymic Disorder
   Depressive Disorder NOS
   Bipolar Disorder
   Mood Disorder NOS
   Mood Disorder due to Medical Condition
   Substance Induced Mood Disorder
   Adjustment Disorder w/ Depressed Mood
Major Depressive Disorder (MDD)
   Depressed or irritable mood
   Loss of interest or pleasure
   Weight loss or weight gain
   Insomnia or hypersomnia
   Psychomotor agitation or retardation
   Fatigue, loss of energy
   Feelings of worthlessness, excessive guilt
   Poor concentration or indecisiveness
   Suicidality
   5 or more of above in same 2-week period
MDD: How common?
    Preschoolers:   1%
    School-age:     2%
    Adolescents:    4-9%
    Adults:          6-9%

    Relapse rates: 50-60%
    Recent cohort studies: increased incidence, earlier age
     of onset, more severe sx (implications as aging
     occurs)
    Sex differences: none for school-age; by teen years,
     affects more females than males, across cultures
Dysthymic Disorder
   Insidious onset
   Chronic course
   Duration greater than one year
   High risk for MDD (“Double depression”)
   Prevalence: 4-8%
Bipolar Disorder
   No special DSM-IV provisions for children
   Complicated differential diagnosis (nonaffective
    psychoses, unipolar depression, organic syndromes,
    ADHD, and disruptive behavior disorders)
   Prevalence: 1-2% with no sex differences
   MDD, dysthymia as precursors
“Sub-threshold” Issues
 How depressed is depressed?
 Issue of criterion
 Determination of diagnosis especially difficult
  in context of “adolescent turmoil”
 Even if formal criteria are not met, still
  requires sensitivity to subclinical depressed
  mood
Adolescent depression
   M:F=1:2, across cultures
   Greater frequency, intensity, earlier onset in each
    generation since the ’40s
   May or may not parallel adult form
   Irritable, angry affect may predominate (different
    from “typical” oppositionalism)
   More mood variability (can look fine at times)
   Course: episode duration in clinical samples: 7-9
    months; 40-60% relapse in 2 yrs
   Less inclined to be referred for tx than disruptive
    disorders
Treatment considerations
   Identifying teens who need professional help for
    depression can be difficult
   Introversive teen can be overlooked, disruptive,
    substance-abusing teens may not be seen as depressed
   Finding treatment can be difficult (7,000 child and
    adolescent psychiatrists in US), especially in low-
    income areas
   Demand outweighs resources
Treatments: Psychosocial
   Cognitive therapy (addresses negative views of self,
    world and the future)

   Interpersonal therapy (emphasis on current
    relationships; use of rehearsal, role play)

   Family therapy (communication skills, structural
    realignment)

   Dialectical behavior therapy (DBT)
Suicidality
 A symptom, not a disorder itself
 Teen suicide: still a rare event
 Often (but not exclusively) associated with
  depression
 3rd leading cause of death ages 15-19
 Threefold increase from ’50s to early ’90s
 Recent decreases across racial groups
Protective factors
   Family cohesion
   Social supports
   Religiosity
   Problem-solving skills
   Ability/willingness to verbalize
   Treatment
Prevention efforts
   In general, problematic
   School-based educational programs create more risk
    than benefit
   Screenings: many false positives; also question of
    available resources (600 calls/month at SCH)
   Crisis hotlines: mixed effects; most studies show no
    significant effects; teens do not tend to use them
Exercise
   In your groups of 4:
       Consider a school activity that could either foster/
        enhance depression, or help a student recover
       What could a teacher do to make the activity a
        health-ful one

       Example: Standardized test – teacher could
        berate students about need for excellence, or be
        more supportive

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Understanding Depression and Anxiety in Students

  • 1. Understanding and Teaching Students with Anxiety and Depression Rona Milch Novick, PhD Rev 1/11
  • 2. Erica’s Story Erica is a middle school student, who has always been a bit clingy, shy and nervous. This year, during a school trip she got sick and threw up on the bus. Ever since, she has refused to go on the school bus. She will not take gym class, complaining that running around makes her feel like she will be sick. She refuses to go to school many mornings, and spends a lot of time in the nurse’s office, saying she thinks she is going to be sick.
  • 3. Yossi’s Story Yossi transferred to the all boy’s high school for 10th grade saying he wanted a new start. He failed most subjects in 9th grade and his parents say he became really withdrawn, no longer hanging out with his friends. When asked about it he said it’s just not fun anymore. He says he hopes the change in school will help but doubts it since he is not really good at anything and will probably fail. His parents also find him more angry and disrespectful, and he seems to want to sleep constantly.
  • 4. Think- Pair- Share What Does This Have to Do With School?  List 3 ways anxiety could interfere with school success  List 3 ways depression could interfere with school success
  • 6. Anxiety and Avoidance Stimulus Anxiety Avoidance Decreased Anxiety
  • 7. Components of Anxiety Triple Response Mode:  Physiological arousal  Hypervigilance/worry  Behavioral avoidance (as a result)
  • 8. Impacts of Anxiety In School Settings  Negatively affects academic work and school performance  Impairments in social adjustment  Decreased social acceptance  Low global self worth  Co-morbidity is significant  12% depression  15% oppositional defiant disorder  17% ADHD  50-75% another anxiety disorder
  • 9. Psychiatric difficulties in youth  American Academy of Pediatrics: 20% of children aged 4-15 have psychological or behavioral problems (2x increase since 1980)  Estimates of actual psychiatric disorders:  12 million American children and teens  5-15% of 9-10 year olds  15-20% of adolescents  Adult comparison: 20%  Criteria: DSM-IV, including symptom severity and impairment in functioning (family school, peers)
  • 10. Etiology  Biological disorders of neurotransmitters  Emergence of disorders precipitated by:  genetic vulnerability  deficient social supports  family dysfunction  trauma  chronic environmental stress
  • 11. How Prevalent Are Anxiety Disorders?  Most common psychiatric disorder in children  Estimated 10-20% incidence rate  Anxiety symptoms are persistent over time  Prognosis poor if untreated  More common in girls  Up to 30% of all children may exhibit subclinical levels of worry
  • 12. Anxiety Interventions as Resilience Builders  Cognitive Behavioral Interventions  Cognitive techniques  Metacognitive lessons on healthy thinking  Skill building  Imagery, emotional literacy, other direct skills  Relaxation training
  • 13. Negative Thinking Exercise  With your group of 4, review the common negative thought patterns  Create examples for three of these and, without indentifying which type of negative thought pattern they are, write them on your paper  Groups will rotate around the room and attempt to indentify the negative thought pattern in each example
  • 14. Exercise Debrief  Pedagogic technique – having students create examples increases learning  “Carousel” often involves movement, possibility for non-verbal responding, repeated practice
  • 15. School Involvement in Treatment  Majority of child’s time is in school  School is child’s natural environment, generalization is essential  School requires intact cognitive and social functioning  School personnel are central in child’s life
  • 16. Interventions  Behavioral and Cognitive-Behavioral Treatments  Exposure  Response Prevention  Relaxation/Imagery  Reinforced practice/Operant techniques  Cognitive Techniques  Family Treatment  Psychopharmacology  Clomipramine  SSRI’s
  • 17. Need for Sensitivity: Role of Schools  Any and all school personnel can be part of solution or problem  All school personnel must understand disorder and students’ needs  All school personnel should respond sensitively and therapeutically  Communication between school, home and outside professionals is essential
  • 18. Intervention – Helping Those With Special Needs  Slow but steady movement  Avoid avoidance  Communication across settings  Reinforcement of learned skills  Generalization training
  • 19. Reaction Handling Anxious Reactions  Match anxiety with calm  Prompt for skill use  Attempt not to go backwards – even if forwards is impossible  View as temporary crisis  Reinforce non-anxious behavior but use caution in penalizing anxious behavior
  • 20. Anxiety Disorder Diagnoses  Separation Anxiety Disorder  Generalized Anxiety Disorder  Social Phobia  Selective Mutism  Obsessive Compulsive Disorder *School Phobia is not formal diagnosis
  • 21. Generalized Anxiety Disorder  Excessive and unrealistic worries  About competence, approval, future, past  Extreme self-consciousness  Excessive need for reassurance  Inability to relax  Somatic complaints  Trouble concentrating  Sleep disturbance  Fatigued  Symptoms for 6 months or more
  • 22. Separation Anxiety Disorder Developmentally inappropriate & excessive anxiety concerning separation from home or attachment figures, with 3 or more  recurrent excessive distress at separation  persistent and excessive worry about losing or harm befalling attachment figures  persistent reluctance or refusal to go to school or elsewhere  persistent fearfulness at being alone  persistent reluctance to go to sleep without being near major attachment figure  repeated nightmares about separation  repeated c/o physical symptoms at separation or when anticipated
  • 23. Separation Anxiety - cont’d  Duration of at least 4 weeks  Onset before age 18  Clinically significant distress  Not PDD, Schizophrenia, Psychotic disorder, or Panic Disorder in adolescents
  • 24. Selective Mutism  Rare, fewer than 1% of referrals  Usually begins in preschool  Many children reported as shy
  • 25. School Phobia  Not a formal diagnosis  Variant of separation anxiety disorder, social phobia or other anxiety disorder  Rarely actual phobia to school setting  Distinguish from truancy and school refusal
  • 26. Obsessive Compulsive Disorder  Presence of obsessions or compulsion  Obsessions are  persistent ideas - intrusive  unable to ignore  Compulsions are  repetitive behavior or thought driven to perform in response to obsession  Aimed at preventing distress  Causes marked distress  Child knows O/C are unreasonable
  • 27. Video Watching Guide (Selective Mutism)  What is one thing you heard that you didn’t know  What is one thing you would do differently as a result of watching the video
  • 28. Depression in Children and Adolescents  How does depression effect learning?  How does depression effect testing?  How does depression effect other aspects of school functioning?  http://www.youtube.com/watch?v=S1PPCzRkBKQ
  • 29. Depressed mood and depressive disorders  Depressed mood relatively common:  10% school-age children  40% adolescents  If persistent and severe:  Affective disorders, including Major Depressive Disorder, Bipolar Disorder, Dysthymic Disorder  Fewer than 1 in 5 young people who need tx for depression get it
  • 30. Historical trends  “Parents are too stern, chide, brawl, whip and strike… children are so disheartened they never have a merry hour in their lives…” (Burton, 1621)  Depression-like features in children whose attachment was not initiated, interrupted, or lost (Bowlby, Spitz, A. Freud, ’30s-’60s)  “Masked depression” (’50s-’70s)  Mood disorders of youth parallel adults (70s+)
  • 31. Models of depression – with relevance for school settings  Learned helplessness (behavior independent of reinforcement)  http://www.youtube.com/watch?v =gFmFOmprTt0  Cognitive distortions (negative views of self, environment and the future)  Life stress (SES, family factors, poor social supports)  Genetic/Biochemical (neurotransmitters)
  • 32. Neurotransmitters  Serotonin: low levels associated with violence, suicidality (decreased CSF concentration of 5HIAA)  Dopamine: increase of dopamine activity implicated in psychotic depression  Norepinephrine: abnormalities found in urinary MHPG of depressed patients
  • 33. Assessment  Need for multiple respondents  Clinical interview (structured?)  Rating scales (CDI, Beck, CBCL, BASC)  Psychological testing  Behavior observation  DSM-IV
  • 34. Mood disorders  Major Depressive Disorder  Dysthymic Disorder  Depressive Disorder NOS  Bipolar Disorder  Mood Disorder NOS  Mood Disorder due to Medical Condition  Substance Induced Mood Disorder  Adjustment Disorder w/ Depressed Mood
  • 35. Major Depressive Disorder (MDD)  Depressed or irritable mood  Loss of interest or pleasure  Weight loss or weight gain  Insomnia or hypersomnia  Psychomotor agitation or retardation  Fatigue, loss of energy  Feelings of worthlessness, excessive guilt  Poor concentration or indecisiveness  Suicidality  5 or more of above in same 2-week period
  • 36. MDD: How common?  Preschoolers: 1%  School-age: 2%  Adolescents: 4-9%  Adults: 6-9%  Relapse rates: 50-60%  Recent cohort studies: increased incidence, earlier age of onset, more severe sx (implications as aging occurs)  Sex differences: none for school-age; by teen years, affects more females than males, across cultures
  • 37. Dysthymic Disorder  Insidious onset  Chronic course  Duration greater than one year  High risk for MDD (“Double depression”)  Prevalence: 4-8%
  • 38. Bipolar Disorder  No special DSM-IV provisions for children  Complicated differential diagnosis (nonaffective psychoses, unipolar depression, organic syndromes, ADHD, and disruptive behavior disorders)  Prevalence: 1-2% with no sex differences  MDD, dysthymia as precursors
  • 39. “Sub-threshold” Issues  How depressed is depressed?  Issue of criterion  Determination of diagnosis especially difficult in context of “adolescent turmoil”  Even if formal criteria are not met, still requires sensitivity to subclinical depressed mood
  • 40. Adolescent depression  M:F=1:2, across cultures  Greater frequency, intensity, earlier onset in each generation since the ’40s  May or may not parallel adult form  Irritable, angry affect may predominate (different from “typical” oppositionalism)  More mood variability (can look fine at times)  Course: episode duration in clinical samples: 7-9 months; 40-60% relapse in 2 yrs  Less inclined to be referred for tx than disruptive disorders
  • 41. Treatment considerations  Identifying teens who need professional help for depression can be difficult  Introversive teen can be overlooked, disruptive, substance-abusing teens may not be seen as depressed  Finding treatment can be difficult (7,000 child and adolescent psychiatrists in US), especially in low- income areas  Demand outweighs resources
  • 42. Treatments: Psychosocial  Cognitive therapy (addresses negative views of self, world and the future)  Interpersonal therapy (emphasis on current relationships; use of rehearsal, role play)  Family therapy (communication skills, structural realignment)  Dialectical behavior therapy (DBT)
  • 43. Suicidality  A symptom, not a disorder itself  Teen suicide: still a rare event  Often (but not exclusively) associated with depression  3rd leading cause of death ages 15-19  Threefold increase from ’50s to early ’90s  Recent decreases across racial groups
  • 44. Protective factors  Family cohesion  Social supports  Religiosity  Problem-solving skills  Ability/willingness to verbalize  Treatment
  • 45. Prevention efforts  In general, problematic  School-based educational programs create more risk than benefit  Screenings: many false positives; also question of available resources (600 calls/month at SCH)  Crisis hotlines: mixed effects; most studies show no significant effects; teens do not tend to use them
  • 46. Exercise  In your groups of 4:  Consider a school activity that could either foster/ enhance depression, or help a student recover  What could a teacher do to make the activity a health-ful one  Example: Standardized test – teacher could berate students about need for excellence, or be more supportive

Hinweis der Redaktion

  1. Welcome – Introduce myself and SMHA My background as a clinician specializing in treating children with anxiety disorders and as a consultant to schools, and program developer In all cases of anxious kids, whether with ocd, gad, sel mutism or sep anx, I often work closely with schools, and have found their assistance absolutely crucial. Wearing my other hat, I have been struck by how many consultations from schools I receive for problem behaviors, and how few for students with anxiety disorders. So I am here today with a 2 fold mission – first, to present information on what is normal worry and anxiety, and when it becomes problematic. Second, to increase the sensitivity, awareness, and concern about anxiety disorders in schools so students receive the early identification and assistance they need.
  2. The blue dotted lines show how avoidance reinforces the connections between avoidance and decreased anxiety, thereby increasing the liklihood of continued avoidance, and the connection between the stimulus and anxiety, thereby cementing the anxious symptoms. Because of generalization, and because of the extremely negative experience of anxiety- children will not only avoid situations that make them anxious, but situations like them, or situations close to them in time. (For example – sep anxious child who also stays close to parent in the home) Secondarily, since avoidance robs the child of the opportunity to “test” out safe situations, it cements the symptoms Conclusion: to address anxiety sx, must find a way to eliminate avoidance
  3. This is not a small problem! Highlight issues on slide and give examples
  4. Despite these facts, as I mentioned, it is under recognized in schools Anxious children may be ideal students Hard to know what is normative – especially at young ages, many students have transient or limited anxiety symptoms – this doesn ‘t mean it is a disorder This may seem to argue for caution in making diagnosis, however, lets look at the impact of anxiety for students
  5. Why is the school so important It is the place child spends most of time – what good is a treatment that eliminates a problem for 4 hrs/day, or only 2 days/week Children will spend 6-8 hours daily for upwards of 12 years in school – any reasonable treatment must generalize to that setting School is impossible if you’re thinking is impaired – or if all your psychic energy is spent on managing your anxiety School is also a social setting – and so many of the anxiety disorders have direct or indirect effects on social functioning – This means failure to address anxiety disorders will impair students social functioning in the academic setting School personnel are a powerful resource – not only because of the time they spend with students, but because of the nature of their relationship
  6. Review DSM diagnosis – and differences for children Emphasize the pathology and give examples