1. Proprietary and Confidential. ©2013 Syapse
Enabling Clinical Omics

2. Proprietary and Confidential. ©2013 Syapse
About Me
Stanford Phd Dropout (Neuro)
Alzheimer’s Research
Biopharma Clinical & Biz Dev
Founder, Syapse (at Stanford)
Board, SXSW Accelerator
@jonathanhirsch
jon@syapse.com

3. Proprietary and Confidential. ©2013 Syapse
Problem
38%
40%
43%
50%
70%
75%
Asthma Drugs Arthritis Drugs Cancer Drugs
Antidepressants Diabetes Drugs Alzheimer’s Drugs

4. Proprietary and Confidential. ©2013 Syapse
PersonalizedTherapies

5. Proprietary and Confidential. ©2013 Syapse
LS Crohn’s Ulcerative
Colitis
Healthy
Smarr, Calit2
Omics: MoreThan Just Genomics

6. Proprietary and Confidential. ©2013 Syapse
Microbiome in Clinical Care

7. Proprietary and Confidential. ©2013 Syapse
Single Patient Multi-Omics Profile
Genome Proteome
Transcriptome
Microbiome
Epigenome
Immunome
Metabalome

8. Proprietary and Confidential. ©2013 Syapse
Rapidly Falling Costs

9. Proprietary and Confidential. ©2013 Syapse
Problem
API for healthcare

10. Proprietary and Confidential. ©2013 Syapse
Problem
No or Bad Software

11. Proprietary and Confidential. ©2013 Syapse
Enabling Clinical Omics
“A startup called Syapse is trying to bring the world of
“omics” under control with a new data management platform
based on some of the same general techniques that also
power Facebook’s Graph Search.”
- GigaOM
Syapse software enables the generation and use
of omics profiles at laboratories and healthcare
providers to diagnose and treat patients.

12. Proprietary and Confidential. ©2013 Syapse
Syapse Product Suite
Syapse for
Hospitals
Syapse for
Labs
Syapse Platform

13. Proprietary and Confidential. ©2013 Syapse
Syapse Platform
Syapse Platform
(semantic computing)
Omics
Profiles
Phenotype
& EMR Drugs
& Trials
Outcomes
Knowledge
& Rules

14. Proprietary and Confidential. ©2013 Syapse
Clinical diagnostics workflow
Curation
Sample Accession
& Processing
Results
Storage
Analytical
Pipeline
Report
Delivery
Outcome
Tracking
Syapse for Labs
Report
Generation
Syapse for Labs
OME
Results Portal
Interfaces to 3rd-party tools

15. Proprietary and Confidential. ©2013 Syapse
Initiatives
Free the Data
www.free-the-data.org

16. Proprietary and Confidential. ©2013 Syapse
About Syapse
Team of 15, based in Palo Alto
We’re hiring!

17. Proprietary and Confidential. ©2013 Syapse
Enabling Clinical Omics