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SELLA and JUXTASELLAR anatomy
SPHENOID BONE

• head – body
  feet – pterygoid process
  wings




• Body of sphenoid –
       planum sphenoidale
       sella
SPHENOID BONE
• Body of sphenoid –
       planum sphenoidale
       Sella turcica (turkish saddle)
Planum sphenoidale
Limbus

Chiasmatic groove
Sella

Carotid sulcus
SOF
1.   Frontal sinus
2.    Ethmoid sinus
3.   Sphenoid sinus
4.   Maxillary sinus
5.   Anterior clinoid
     process
6.   Sella turcica
     (pituitary fossa)
7.   Postr. clinoid pr
8.   Clivus
9.   Petrous bone
CAVERNOUS SINUS




                Lee J H et al. AJR 2003;181:583-590


©2003 by American Roentgen Ray Society
DIAPHRAGMA SELLA
PITUTARY
• In cases of visual failure / endocrine
  abnormality.

• At the level of optic nerve.
• Situated in pituitary fossa – above the sphenoid sinus, with
  cavernous sinus on each side.
• Superiorly suprasellar cistern is present.
• < 8 - 9mm height.
• Infundibulum is large in females
• Normal pituitary enhance with contrast on CT / MRI.
• Antr. Adenohypophysis – dovelops from ratke’s pouch
• Postr. neurohypophysis, infundibulum – dovelops from
  downgrowth of neuroectoderm
Tuber cinareum is the lamina of grey matter – b/w mammillary body
and optic chiasma.
CORONAL T 1 images with thin
    (3 mm) sections




•   Anterior lobe is ISOINTENSE on T1 and T2
•   Posterior lobe is HYPERINTENSE on T1 and HYPO on T2.
•   Infundibulum is HYPERINTENSE on FLAIR.
•   Rim of hypointensity – cortical bone of dorsum sella
•   Hyperintense marrow of clivus postr. to it.
T2-weighted, coronal section. 1, Pituitary gland. 2, Infudibulum. 3, Optic
chiasma. 4, Lateral ventricle.5, Anterior cerebral artery. 6, Middle cerebral
artery. 7, Sphenoidal sinus.
MRI of the pituitary gland.
T1-weighted coronal section. 1, Pituitary gland. 2, Infudibulum. 3, Chiasma. 4, Lateral
ventricle. 5,Anterior cerebral artery. 6, Middle cerebral artery. 7, Sphenoidal sinus.
T1 coronal section (after iv contrast media) 1, Pituitary
gland. 2, Infudibulum. 3, Chiasma. 4, Lateral ventricle. 5, Anterior cerebral
artery. 6, Middle cerebral artery. 7, Sphenoidal sinus
T1-weighted, sagittal section. 1, Genu, corpus callosum . 2, Splenium, corpus
callosum . 3,Neurohypophysis. 4, Adenohypophysis.
T1 sagittal section (after iv contrast medium) 1, Genu, corpus callosum
. 2, Splenium, corpus callosum . 3, Neurohypophysis. 4, Adenohypophysis.
DIENCEPHALON
• Diencephalon is divided into two halves by 3rd ventricle.
• Each diencephalon has dorsal and ventral parts, demarcated by
  ‘hypothalamic sulcus’.
      dorsal – thalamus, epithalamus
      ventral – hypothalamus, subthalamus




                                             RadioGraphics 2007; 27:1087–1108
THALAMUS
• Ovoid mass of grey matter
• Poles – antr. : postr. boundary of IV foramen.
          postr. (PULVINAR) : projects
  beyond 3rd V , lies just above and
  lateral to colliculi.
• Upper surface – dorsolaterally thalamostriate V and S.terminalis.
                    part of floor of 3rd ventricle.
• Inferior surface - continues with tegmentum of mid brain
• Medially – 3rd ventricle
• Laterally – lentiform N, separated by internal capsule.



Two thalami are apposed medially
 by massa intermedia.
EPITHALAMUS

1.   Pineal body
2.   Habenular N
3.   Habenular comissure
4.   Posterior comissure



 PINEAL BODY : balloon shaped – projects backwards below the
  splenium of corpus callosum and rests over supr. colliculi.

 HABENULAR NUCLEI : situated in habenular trigone.

 COMISSURES - habenular and posterior .
1,Posterior commissure.
2, Habenular commissure.
3, Internal cerebral vein
4, Splenium, corpus callosum.
5, Pineal gland.
6, Cerebellum.
7, Tectum
1, Pineal gland.
2, Habenula.
3, Third ventricle.
4, Pulvinar.
5, Lateral ventricle
HYPOTHALAMUS
• Most ventral part of diencephalon , and it
  forms floor and wall of antr. 1/3rd of 3rd V.
• Extent : lamina terminalis to mammillary bodies

• Relations : dorsally – hypothalamic sulcus
              ventral – floor of 3rd ventricle. It
  constitutes mamillary bodies, infundibulum, optic chiasma.
              medial – 3rd ventricle
              lateral – internal capsule and subthalamus

  Tuber cinerium extends posteriorly from infundibulum to
  mamillary bodies
MAMMILLARY BODIES
•   These are one of the nuclear masses of hypothalamus.
•   Each contains – medial, lateral and intercalated nuclei.
•   Receive fibres from fornix and efferents to antr. thalamus.
•   Postr. to mammillary bodies, lies postr. perforated substance.
MAMILLARY BODIES
BASAL GANGLIA
• Corpus Striatum = Caudate N + Lentiform N (P + GP) .
• Amygdala – tail of caudate N comes in contact with amygdala ,
  but without any structural or functional connections
• Claustrum – thin strip of grey matter
              b/w putamen and insula
CAUDATE NUCLEUS
             ‘C’ shaped with concavity facing inferiorly.
• Head – indents the frontal horn.
           (shape same in axial and coronal cuts)
• Body – starts from IV foramen and is seen along side of lateral
  ventricle.
• Tail – lies above temporal
   horn ; continues with
   amygdala.
• Lentiform N –
     supr. – C. radiata and C. callosum.
     infr. – antr. perforated substance and antr. comissure.

• Internal capsule – ‘boomrang’
         shaped thick white matter.
LIMBIC SYSTEM
1.   Olfactory pathway
2.   Pyriform lobe
3.   Limbic lobe
4.   Amygdala
5.   Hippocampal complex
6.   Parts of hypothalamus
     and thalamus
• Pyriform lobe – uncus + antr. parahippocampal gyrus
• Hippocampal complex - dentate gyrus + hippocampus +
  fornix
• Limbic lobe – septal areas + cingulate gyrus + PHG
HIPPOCAMPUS
• Lies on floor of temporal horn of lateral V.
• Parts : head and tail – curves medially
          body – seen on parasaggital
          plane.




 Hungarian neuroscientist Laszlo Seress' 1980 preparation
Hippocampus terminates
posteriorly beneath splenium.
 INDUSIUM GRISEUM : vestigial
• thin sheet of grey matter covering outer convex surface of
  corpus callosum.
• Contains medial and lateral longitudinal striae.
• Antr.ly it continue as paraterminal gyrus.
  Postr.ly continues as dentate gyrus.
• On coronal cuts, it is seen as rolled structure containing Ammon’s
  horn and dentate gyrus. Ammon’s horn continues with the PHG
  and is convex laterally.
• Relations : above and lateral to it – temporal horn of lateral V.
  (above temporal horn is tail of caudate N , and supr. to it is
  amygdyla).

• PHG – is present on medial aspect of temporal lobe
       antr.ly it continue as uncus
Radiology :
hippocampal gyrus – on axial plane
rolled shape - coronal plane
flattened – saggital plane
AMYGDALA
• Present at roof of infr. horn of lateral ventricle , close to its tip.
• Continues behind with tail of caudate N.
• Stria terminalis starts from it.
FORNIX
• Sole efferent fibres from fornix
• Begin from hippocampus as alveus and fimbriae.
• Parts –
     - crura
     - body
     - columns
     - comissure
• On reaching splenium, fimbriae divide into –
               dorsal fornix – continue as inducium gracium.
               ventral fornix – fornix proper.

• Upper surface of body is related to SP. At level of IV foramen, apex
  divides into two columns.
MRI of the brain, T1-
weighted sagittal cut.

 1, Column of fornix.
 2, Corpus callosum.
 3, Midbrain.
 4, Pons.
 5, Cerebellum
1, Column of fornix. 2, Corpus callosum.   1, Column of fornix.   2, Lentiform nucleus.
3, Caudatus nucleus. 4, Hippocampus        3, Corpus callosum. 4, Crus of fornix.
MID BRAIN
• Dorsal tectum : 4 colliculi = corpora quadrigemina
• Ventral cerebral peduncles :
          ventral crus cerebri – CST
          dorsal tegmentum – cranial N nuclei . Both are
  seperated by substantia nigra.


  (triangular space between two peduncles is
  Interpeduncular cistern)
• Red nucleus : dorsomedial to S.nigra. It is present at the level of
  supr. colliculus .

• Both red nucleus and S. nigra
  are hypointense on T2 W MRI.
  (both cannot be seen on CT)

• Lower midbrain – laterally ambient
  cistern and posteriorly
  quadrigeminal cistern.

(Interpeduncular fossa is limited antr.ly
by mamillary bodies)
HIND BRAIN
                     Pons , medulla and cerebellum
 PONS
• Axial cuts of lower pons has posterolaterally directed middle
  cerebellar peduncles – lateral to which are CP angle cisterns.
• Supr. cerebellar peduncles – at the level of mid pons.
MEDULLA

• 3 cm length.
• Ventral - pyramids (b/w median fissure
  & anterolat. sulcus).
   Lateral to it are olives.

• Dorsal – fasciculus gracilis (M) &
  cuneatus (L).

• On axial CT / MRI – pear shaped (lower pons) ;
                     square shaped on cephalad cuts , at the level of
  F of magendie .
Pontomedullary junction
     Prominent pontomedullary sulcus on each lateral
  wall and ventral fissure is replaced by BROADER basilar
  sulcus.
 CEREBELLUM
• Cerebellar cortical ridges = Folia
• On section cerebellum has a tree like config , so known as
  ‘Arbor vitae’.
• Cerebellum – vermis and 2 lobes – divided by para median sulci.

• Deep transverse fissures divide cerebellum into 3 lobes
  (on SAGGITAL MRI) :
 Antr. – lingula, central lobule, culmen
 Postr. – declive, folium, tuber, pyramid, uvula.
 Nodule – flocconodular lobe

• Nodule is the most ventral part
  seen on axial scans lying postrior                          to
  4th ventricle.
From the level of
ponto medullary
junction, occipital
lobe is seen in axial
cuts
• Three cerebellar peduncles are present
 superior CP – mid brain (brachium conjunctivum)
 middle CP – pons (brachium pontis)
 inferior CP – medulla (restiform body).
COMISSURES OF BRAIN
White matter tracts that cross the midline, connecting the
two cerebral hemispheres.

1. Corpus callosum

2. Anterior commissure

3. Habenular commissure

4. Posterior commissure

5. Supraoptic commissures : Gudden's commissure
                            Meynert's commissure
Corpus callosum
• Parts – rostrum, genu, body, and splenium.
• Forceps minor (frontal) and major (occipital).
• In Saggital sections , it is curved in shape.
Anterior comissure

• Myelinated fibers at antr. limit of diencephalon (lamina
  terminalis)
• On MRI , seen as convex arc of fibers – useful to locate
  perivascular spaces along its lateral aspect.

• Line joining AC--PC is used
  as standard reference in
  stereotactic surgery.
Imaging sectional anatomy of brain   part 2

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Imaging sectional anatomy of brain part 2

  • 1.
  • 3. SPHENOID BONE • head – body feet – pterygoid process wings • Body of sphenoid – planum sphenoidale sella
  • 4. SPHENOID BONE • Body of sphenoid – planum sphenoidale Sella turcica (turkish saddle)
  • 6.
  • 7.
  • 8. 1. Frontal sinus 2. Ethmoid sinus 3. Sphenoid sinus 4. Maxillary sinus 5. Anterior clinoid process 6. Sella turcica (pituitary fossa) 7. Postr. clinoid pr 8. Clivus 9. Petrous bone
  • 9.
  • 10. CAVERNOUS SINUS Lee J H et al. AJR 2003;181:583-590 ©2003 by American Roentgen Ray Society
  • 11.
  • 12.
  • 13.
  • 15.
  • 16.
  • 17.
  • 18. PITUTARY • In cases of visual failure / endocrine abnormality. • At the level of optic nerve. • Situated in pituitary fossa – above the sphenoid sinus, with cavernous sinus on each side. • Superiorly suprasellar cistern is present. • < 8 - 9mm height. • Infundibulum is large in females • Normal pituitary enhance with contrast on CT / MRI.
  • 19. • Antr. Adenohypophysis – dovelops from ratke’s pouch • Postr. neurohypophysis, infundibulum – dovelops from downgrowth of neuroectoderm
  • 20. Tuber cinareum is the lamina of grey matter – b/w mammillary body and optic chiasma.
  • 21.
  • 22. CORONAL T 1 images with thin (3 mm) sections • Anterior lobe is ISOINTENSE on T1 and T2 • Posterior lobe is HYPERINTENSE on T1 and HYPO on T2. • Infundibulum is HYPERINTENSE on FLAIR. • Rim of hypointensity – cortical bone of dorsum sella • Hyperintense marrow of clivus postr. to it.
  • 23. T2-weighted, coronal section. 1, Pituitary gland. 2, Infudibulum. 3, Optic chiasma. 4, Lateral ventricle.5, Anterior cerebral artery. 6, Middle cerebral artery. 7, Sphenoidal sinus.
  • 24. MRI of the pituitary gland. T1-weighted coronal section. 1, Pituitary gland. 2, Infudibulum. 3, Chiasma. 4, Lateral ventricle. 5,Anterior cerebral artery. 6, Middle cerebral artery. 7, Sphenoidal sinus.
  • 25. T1 coronal section (after iv contrast media) 1, Pituitary gland. 2, Infudibulum. 3, Chiasma. 4, Lateral ventricle. 5, Anterior cerebral artery. 6, Middle cerebral artery. 7, Sphenoidal sinus
  • 26. T1-weighted, sagittal section. 1, Genu, corpus callosum . 2, Splenium, corpus callosum . 3,Neurohypophysis. 4, Adenohypophysis.
  • 27. T1 sagittal section (after iv contrast medium) 1, Genu, corpus callosum . 2, Splenium, corpus callosum . 3, Neurohypophysis. 4, Adenohypophysis.
  • 29. • Diencephalon is divided into two halves by 3rd ventricle. • Each diencephalon has dorsal and ventral parts, demarcated by ‘hypothalamic sulcus’. dorsal – thalamus, epithalamus ventral – hypothalamus, subthalamus RadioGraphics 2007; 27:1087–1108
  • 30. THALAMUS • Ovoid mass of grey matter • Poles – antr. : postr. boundary of IV foramen. postr. (PULVINAR) : projects beyond 3rd V , lies just above and lateral to colliculi.
  • 31. • Upper surface – dorsolaterally thalamostriate V and S.terminalis. part of floor of 3rd ventricle. • Inferior surface - continues with tegmentum of mid brain • Medially – 3rd ventricle • Laterally – lentiform N, separated by internal capsule. Two thalami are apposed medially by massa intermedia.
  • 32.
  • 33.
  • 34. EPITHALAMUS 1. Pineal body 2. Habenular N 3. Habenular comissure 4. Posterior comissure  PINEAL BODY : balloon shaped – projects backwards below the splenium of corpus callosum and rests over supr. colliculi.  HABENULAR NUCLEI : situated in habenular trigone.  COMISSURES - habenular and posterior .
  • 35.
  • 36.
  • 37. 1,Posterior commissure. 2, Habenular commissure. 3, Internal cerebral vein 4, Splenium, corpus callosum. 5, Pineal gland. 6, Cerebellum. 7, Tectum
  • 38. 1, Pineal gland. 2, Habenula. 3, Third ventricle. 4, Pulvinar. 5, Lateral ventricle
  • 39. HYPOTHALAMUS • Most ventral part of diencephalon , and it forms floor and wall of antr. 1/3rd of 3rd V. • Extent : lamina terminalis to mammillary bodies • Relations : dorsally – hypothalamic sulcus ventral – floor of 3rd ventricle. It constitutes mamillary bodies, infundibulum, optic chiasma. medial – 3rd ventricle lateral – internal capsule and subthalamus Tuber cinerium extends posteriorly from infundibulum to mamillary bodies
  • 40.
  • 41.
  • 42.
  • 43.
  • 44. MAMMILLARY BODIES • These are one of the nuclear masses of hypothalamus. • Each contains – medial, lateral and intercalated nuclei. • Receive fibres from fornix and efferents to antr. thalamus. • Postr. to mammillary bodies, lies postr. perforated substance.
  • 46.
  • 47.
  • 48. BASAL GANGLIA • Corpus Striatum = Caudate N + Lentiform N (P + GP) . • Amygdala – tail of caudate N comes in contact with amygdala , but without any structural or functional connections • Claustrum – thin strip of grey matter b/w putamen and insula
  • 49.
  • 50. CAUDATE NUCLEUS ‘C’ shaped with concavity facing inferiorly. • Head – indents the frontal horn. (shape same in axial and coronal cuts) • Body – starts from IV foramen and is seen along side of lateral ventricle. • Tail – lies above temporal horn ; continues with amygdala.
  • 51. • Lentiform N – supr. – C. radiata and C. callosum. infr. – antr. perforated substance and antr. comissure. • Internal capsule – ‘boomrang’ shaped thick white matter.
  • 52.
  • 53. LIMBIC SYSTEM 1. Olfactory pathway 2. Pyriform lobe 3. Limbic lobe 4. Amygdala 5. Hippocampal complex 6. Parts of hypothalamus and thalamus
  • 54. • Pyriform lobe – uncus + antr. parahippocampal gyrus • Hippocampal complex - dentate gyrus + hippocampus + fornix • Limbic lobe – septal areas + cingulate gyrus + PHG
  • 55. HIPPOCAMPUS • Lies on floor of temporal horn of lateral V. • Parts : head and tail – curves medially body – seen on parasaggital plane. Hungarian neuroscientist Laszlo Seress' 1980 preparation
  • 57.  INDUSIUM GRISEUM : vestigial • thin sheet of grey matter covering outer convex surface of corpus callosum. • Contains medial and lateral longitudinal striae. • Antr.ly it continue as paraterminal gyrus. Postr.ly continues as dentate gyrus.
  • 58. • On coronal cuts, it is seen as rolled structure containing Ammon’s horn and dentate gyrus. Ammon’s horn continues with the PHG and is convex laterally.
  • 59. • Relations : above and lateral to it – temporal horn of lateral V. (above temporal horn is tail of caudate N , and supr. to it is amygdyla). • PHG – is present on medial aspect of temporal lobe antr.ly it continue as uncus
  • 60.
  • 61.
  • 62. Radiology : hippocampal gyrus – on axial plane rolled shape - coronal plane flattened – saggital plane
  • 63. AMYGDALA • Present at roof of infr. horn of lateral ventricle , close to its tip. • Continues behind with tail of caudate N. • Stria terminalis starts from it.
  • 64. FORNIX • Sole efferent fibres from fornix • Begin from hippocampus as alveus and fimbriae. • Parts – - crura - body - columns - comissure
  • 65. • On reaching splenium, fimbriae divide into – dorsal fornix – continue as inducium gracium. ventral fornix – fornix proper. • Upper surface of body is related to SP. At level of IV foramen, apex divides into two columns.
  • 66. MRI of the brain, T1- weighted sagittal cut. 1, Column of fornix. 2, Corpus callosum. 3, Midbrain. 4, Pons. 5, Cerebellum
  • 67. 1, Column of fornix. 2, Corpus callosum. 1, Column of fornix. 2, Lentiform nucleus. 3, Caudatus nucleus. 4, Hippocampus 3, Corpus callosum. 4, Crus of fornix.
  • 68. MID BRAIN • Dorsal tectum : 4 colliculi = corpora quadrigemina • Ventral cerebral peduncles : ventral crus cerebri – CST dorsal tegmentum – cranial N nuclei . Both are seperated by substantia nigra. (triangular space between two peduncles is Interpeduncular cistern)
  • 69.
  • 70. • Red nucleus : dorsomedial to S.nigra. It is present at the level of supr. colliculus . • Both red nucleus and S. nigra are hypointense on T2 W MRI. (both cannot be seen on CT) • Lower midbrain – laterally ambient cistern and posteriorly quadrigeminal cistern. (Interpeduncular fossa is limited antr.ly by mamillary bodies)
  • 71.
  • 72. HIND BRAIN Pons , medulla and cerebellum  PONS • Axial cuts of lower pons has posterolaterally directed middle cerebellar peduncles – lateral to which are CP angle cisterns. • Supr. cerebellar peduncles – at the level of mid pons.
  • 73.
  • 74.
  • 75. MEDULLA • 3 cm length. • Ventral - pyramids (b/w median fissure & anterolat. sulcus). Lateral to it are olives. • Dorsal – fasciculus gracilis (M) & cuneatus (L). • On axial CT / MRI – pear shaped (lower pons) ; square shaped on cephalad cuts , at the level of F of magendie .
  • 76.
  • 77.
  • 78. Pontomedullary junction Prominent pontomedullary sulcus on each lateral wall and ventral fissure is replaced by BROADER basilar sulcus.
  • 79.  CEREBELLUM • Cerebellar cortical ridges = Folia • On section cerebellum has a tree like config , so known as ‘Arbor vitae’.
  • 80. • Cerebellum – vermis and 2 lobes – divided by para median sulci. • Deep transverse fissures divide cerebellum into 3 lobes (on SAGGITAL MRI) :  Antr. – lingula, central lobule, culmen  Postr. – declive, folium, tuber, pyramid, uvula.  Nodule – flocconodular lobe • Nodule is the most ventral part seen on axial scans lying postrior to 4th ventricle.
  • 81. From the level of ponto medullary junction, occipital lobe is seen in axial cuts
  • 82. • Three cerebellar peduncles are present  superior CP – mid brain (brachium conjunctivum)  middle CP – pons (brachium pontis)  inferior CP – medulla (restiform body).
  • 83.
  • 84.
  • 85. COMISSURES OF BRAIN White matter tracts that cross the midline, connecting the two cerebral hemispheres. 1. Corpus callosum 2. Anterior commissure 3. Habenular commissure 4. Posterior commissure 5. Supraoptic commissures : Gudden's commissure Meynert's commissure
  • 86.
  • 87. Corpus callosum • Parts – rostrum, genu, body, and splenium. • Forceps minor (frontal) and major (occipital). • In Saggital sections , it is curved in shape.
  • 88.
  • 89.
  • 90. Anterior comissure • Myelinated fibers at antr. limit of diencephalon (lamina terminalis) • On MRI , seen as convex arc of fibers – useful to locate perivascular spaces along its lateral aspect. • Line joining AC--PC is used as standard reference in stereotactic surgery.