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The Use of Recombinant Human Activated Protein C for Severe Sepsis ,[object Object],[object Object]
What is Severe Sepsis? ,[object Object]
The Problem ,[object Object],[object Object],[object Object],[object Object]
Physiologic Derangements Occurring in Severe Sepsis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
General Facts about Protein C ,[object Object],[object Object],[object Object],[object Object]
Mechanism of Action for rhAPC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The PROWESS Trial ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
APACHE II Score ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Analysis of the Elderly Population within the PROWESS Trial ,[object Object],[object Object],[object Object],[object Object]
ENHANCE Trial ,[object Object],[object Object],[object Object]
COMPARISONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ENHANCE Trial ,[object Object]
Inferences ,[object Object],[object Object]
Recommendations for use of Xigris (rhAPC)‏ ,[object Object],[object Object]
Adverse Effects of Xigris (rhAPC)‏ ,[object Object],[object Object],[object Object],[object Object]
Contraindications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recommendations for use in Surgical Patients ,[object Object],[object Object]
Recommendations for Concurrent Heparin Use ,[object Object],[object Object],[object Object],[object Object],[object Object]
Recommendations for use in Patients with DIC ,[object Object],[object Object],[object Object]
Use in Patients with Borderline APACHE II  Scores ,[object Object],[object Object],[object Object],[object Object],[object Object]
Pediatric Use for Severe Sepsis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Pediatric Use for Specific Subpopulations ,[object Object]
 
 
Pediatric Use in Meningococcemia and PF ,[object Object],[object Object],[object Object]
Pediatric Use in Meningococcemia and PF ,[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusions: What Every Primary Care Physician Should Know ,[object Object],[object Object],[object Object],[object Object]
Recommendations for Pediatric Use ,[object Object],[object Object],[object Object]
REFERENCES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]

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