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Movement Disorders Parkinson’s Epilepsy
Parkinson’s ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Parkinson Balancing Act Normal Balance Parkinson’s Disease Drug Therapy in Parkinson’s Acetylcholine  Dopamine
Metabolism of Levodopa Levodopa 3,O-Methyldopa Dopamine Degradation  products COMT COMT inhibitors
Treatment of Parkinson’s Amantadine, benztropin, diphenhydramine, trihexyphenidyl Miscellaneous Carbidopa-levodopa/entacapone (Stalevo) Increase DA & inhibit metabolism Selegiline(Eldepryl), Tolcapone (Tasmar), Entacapone (Comtan) Inhibit DA Metabolism Levodopa-carbidopa (Sinemet) Bromocriptine, Pergolide(Permax) Pramipexole(Mirapex), Ropinirole(Requip) Increase DA Stimulate DA receptors Agents Drug Action
Drug Therapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Management ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Case Study Parkinson’s
[object Object],[object Object],[object Object]
Points to Ponder ,[object Object],[object Object],[object Object],[object Object],[object Object]
Epilepsy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview of Triggers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Management of Epilepsy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Seizure Type by Incidence Generalized Tonic-Clonic Partial Other
MOA of Anticonvulsants ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Pharmacologic Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Management of Epilepsy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Case Study Epilepsy
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Points to Ponder ,[object Object],[object Object],[object Object],[object Object],[object Object]

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Movement disorders

  • 2.
  • 3. The Parkinson Balancing Act Normal Balance Parkinson’s Disease Drug Therapy in Parkinson’s Acetylcholine Dopamine
  • 4. Metabolism of Levodopa Levodopa 3,O-Methyldopa Dopamine Degradation products COMT COMT inhibitors
  • 5. Treatment of Parkinson’s Amantadine, benztropin, diphenhydramine, trihexyphenidyl Miscellaneous Carbidopa-levodopa/entacapone (Stalevo) Increase DA & inhibit metabolism Selegiline(Eldepryl), Tolcapone (Tasmar), Entacapone (Comtan) Inhibit DA Metabolism Levodopa-carbidopa (Sinemet) Bromocriptine, Pergolide(Permax) Pramipexole(Mirapex), Ropinirole(Requip) Increase DA Stimulate DA receptors Agents Drug Action
  • 6.
  • 7.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14. Seizure Type by Incidence Generalized Tonic-Clonic Partial Other
  • 15.
  • 16.  
  • 17.
  • 18.
  • 20.
  • 21.