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PONS & MI D-BRAI N
STRUCTURE/BLOOD SUPPLY/CRANIAL NERVES
ATTACHMENTS
Lecture….by Prof. Ansari
Wednesday, January 8, 2014
(for BDS SEMESTER II students only)

1
OBJECTIVES
•
•
•
•
•

Structure of pons and midbrain.
Cranial nerves attachment.
Other nuclei present at these levels.
Blood supply
Cross section- grey matter and white matter.

2
PONS
• It is a part of brain stem.
• It lies between midbrain and medulla oblongata.
• It has a basilar part/ ventral part, and a dorsal part which
forms the floor of IV ventricle.
• Three cranial nerves are related to pons, trigeminal nerve
is attached to the pons on ventral part.
• Abducent nerve is related at the lower border of pons and
pyramid.
• Occulomotor nerve arises at the upper border of pons, in
the interpeduncular fossa.
3
4
CRANIAL
CRANIAL
NERVES
NERVES
ATTACHED
ATTACHED
AT THE BASE
AT THE BASE
OF BRAIN
OF BRAIN

5
CROSS SECTION OF PONS

6
IV
VENTRICLE

TEGMENTUM PART

BASILAR PART

7
8
9
Nuclei of cranial nerves in pons
• Facial nerve nuclei, motor /
sensory/autonomic.
• Trigeminal nuclei, motor/ main
sensory/spinal/ mesencephalic.
• Abducent nucleus / purely motor.
• Nuclei pontis.

10
Floor of IV ventricle

11
White fibers at pons
• Corticopontine fibers
• Corticospinal fibers
• Corticopontocerebellar fibers
• Corticonuclear fibers
• Trapezoid body

12
OVERVIEW OF PONS

13
Mesencephalon
• It is at the cranial end of pons.
• It has a dorsal portion called as tectum.
• The ventral portion is called as cerebral peduncle.
• The space between the two cerebral peduncle is
the interpeduncular fossa.
14
Structures in the
interpeduncular fossa
•
•
•
•
•
•

1.Optic nerve
2.Optic chiasma
3.Optic tract
4.Tuber cinereum
5.Mammillary bodies
6.Ant.perforated
substance.
• 7.Olfactory tract
• 8.Pons
• 9=Uncus
15
Cross section of midbrain
Inferior colliculus

Superior
Cerebellar
Peduncle
decussation

PAG

Substantia
Substantia
nigra
nigra

Cerebral peduncle
Cerebral peduncle
16
Superior colliculus

Oculomotor fibers
17
Various nuclei
at midbrain
•
•
•
•
•
•

Oculomotor nucleus
Trochlear nucleus
Mesencephalic nucleus
Red nucleus
Substantia nigra
Edinger-Westphal nucleus

18
White matter at mesencephalon
• Superior cerebellar peduncles decussations
• Medial lemniscus/lateral lemniscus/trigeminal
lemniscus/spinal lemniscus
• Crus cerebri

19
Blood supply of pons &midbrain
• Cortical branches and central branches arise from basilar
artery and circle of Willis.

• Pontine hemorrhage leads to bursting head ache,
pinpoint pupil, and hyperthermia.

• Injury to the Corticospinal fibers leads to hemiplegia.
20
CIRCLE OF WILLIS

21
Red nucleus and substantia nigra
• They are concerned with the extrapyramidal tract.
• Injury to these nuclei will result in tremors,
Parkinsonism, and nystagmus.
• These symptoms can be corrected by supplementing the
neurotransmitter dopamine.

22
Periaqueductal gray

23
Electrical stimulation of the PAG results in
immediate and profound analgesia
•

Stimulation of the dorsal and lateral aspects of the PAG (in the rat)
can provoke defensive responses characterized by freezing
immobility, running, jumping, tachycardia, and increase in blood
pressure.
•
Stimulation of the caudal ventrolateral PAG can result in an
immobile, relaxed posture known as quiescence.
• It also plays a role in female copulatory behavior.

24
Periaqueductal gray

CEREBRAL
AQUEDUCT

RED NUCLEUS

25
References
• http://legacy.owensboro.kctcs.edu/gcaplan/a
nat/notes/api%20notes%20l%20central
%20nervous%20system-brain.htm
• http://www.dartmouth.edu/~rswenson/Neur
oSci/figures/Figure_15.htm
• http://instruct.uwo.ca/anatomy/530/530note
s.htm#TOPICS
• http://www.mcqsonline.net/2009/05/brainst
em-anatomy-mnemonics.html
26
A 62-year old male has sustained several injuries from a car accident.
Upon administering a neurological examination, you suspect that the
patient has damage to the right caudal medulla. Why do you think this?

A. The patient's right eye exhibits hypertropia and he complains of diplopia,
B. The patient's tongue deviates towards to right when you asked him to stick it out
and his uvula deviates towards the left when you ask him to say, "aahhh".
C. The patient has a loss of taste on the right anterior 2/3rds of his tongue
D. The patient exhibits anosmia (inability to smell)
E. The patient complains of excruciating pain on the right side of his face

27

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The brain stem ii

  • 1. PONS & MI D-BRAI N STRUCTURE/BLOOD SUPPLY/CRANIAL NERVES ATTACHMENTS Lecture….by Prof. Ansari Wednesday, January 8, 2014 (for BDS SEMESTER II students only) 1
  • 2. OBJECTIVES • • • • • Structure of pons and midbrain. Cranial nerves attachment. Other nuclei present at these levels. Blood supply Cross section- grey matter and white matter. 2
  • 3. PONS • It is a part of brain stem. • It lies between midbrain and medulla oblongata. • It has a basilar part/ ventral part, and a dorsal part which forms the floor of IV ventricle. • Three cranial nerves are related to pons, trigeminal nerve is attached to the pons on ventral part. • Abducent nerve is related at the lower border of pons and pyramid. • Occulomotor nerve arises at the upper border of pons, in the interpeduncular fossa. 3
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  • 10. Nuclei of cranial nerves in pons • Facial nerve nuclei, motor / sensory/autonomic. • Trigeminal nuclei, motor/ main sensory/spinal/ mesencephalic. • Abducent nucleus / purely motor. • Nuclei pontis. 10
  • 11. Floor of IV ventricle 11
  • 12. White fibers at pons • Corticopontine fibers • Corticospinal fibers • Corticopontocerebellar fibers • Corticonuclear fibers • Trapezoid body 12
  • 14. Mesencephalon • It is at the cranial end of pons. • It has a dorsal portion called as tectum. • The ventral portion is called as cerebral peduncle. • The space between the two cerebral peduncle is the interpeduncular fossa. 14
  • 15. Structures in the interpeduncular fossa • • • • • • 1.Optic nerve 2.Optic chiasma 3.Optic tract 4.Tuber cinereum 5.Mammillary bodies 6.Ant.perforated substance. • 7.Olfactory tract • 8.Pons • 9=Uncus 15
  • 16. Cross section of midbrain Inferior colliculus Superior Cerebellar Peduncle decussation PAG Substantia Substantia nigra nigra Cerebral peduncle Cerebral peduncle 16
  • 18. Various nuclei at midbrain • • • • • • Oculomotor nucleus Trochlear nucleus Mesencephalic nucleus Red nucleus Substantia nigra Edinger-Westphal nucleus 18
  • 19. White matter at mesencephalon • Superior cerebellar peduncles decussations • Medial lemniscus/lateral lemniscus/trigeminal lemniscus/spinal lemniscus • Crus cerebri 19
  • 20. Blood supply of pons &midbrain • Cortical branches and central branches arise from basilar artery and circle of Willis. • Pontine hemorrhage leads to bursting head ache, pinpoint pupil, and hyperthermia. • Injury to the Corticospinal fibers leads to hemiplegia. 20
  • 22. Red nucleus and substantia nigra • They are concerned with the extrapyramidal tract. • Injury to these nuclei will result in tremors, Parkinsonism, and nystagmus. • These symptoms can be corrected by supplementing the neurotransmitter dopamine. 22
  • 24. Electrical stimulation of the PAG results in immediate and profound analgesia • Stimulation of the dorsal and lateral aspects of the PAG (in the rat) can provoke defensive responses characterized by freezing immobility, running, jumping, tachycardia, and increase in blood pressure. • Stimulation of the caudal ventrolateral PAG can result in an immobile, relaxed posture known as quiescence. • It also plays a role in female copulatory behavior. 24
  • 26. References • http://legacy.owensboro.kctcs.edu/gcaplan/a nat/notes/api%20notes%20l%20central %20nervous%20system-brain.htm • http://www.dartmouth.edu/~rswenson/Neur oSci/figures/Figure_15.htm • http://instruct.uwo.ca/anatomy/530/530note s.htm#TOPICS • http://www.mcqsonline.net/2009/05/brainst em-anatomy-mnemonics.html 26
  • 27. A 62-year old male has sustained several injuries from a car accident. Upon administering a neurological examination, you suspect that the patient has damage to the right caudal medulla. Why do you think this? A. The patient's right eye exhibits hypertropia and he complains of diplopia, B. The patient's tongue deviates towards to right when you asked him to stick it out and his uvula deviates towards the left when you ask him to say, "aahhh". C. The patient has a loss of taste on the right anterior 2/3rds of his tongue D. The patient exhibits anosmia (inability to smell) E. The patient complains of excruciating pain on the right side of his face 27