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Prevention and control of zoonotic
  disease in companion animals
               Dr.Shilpi Das
             Deputy Asst Director
      National Centre for Disease Control
                     Delhi


       Dr.Sashanka Sekhar Dutta
       Chief functionary-JBF-India Trust
               (Just be friendly)
Our
Companions
Zoonoses




An infectious disease transmissible under natural conditions
between vertebrate animals and human beings
     “A dictionary of Epidemiology” 3rd edition ,1995 editied by John M.Last
Importance of Zoonoses
1,415 microbes are infectious for
            human




Of these 868 (61%) are considered zoonotic.
70% of newly recognized pathogens are
zoonoses
Diseases that can be transmitted from animals
                  to human
 Category                       Diseases
Bacterial   Salmonellosis, Brucellosis, Cat Scratch
            Disease,Leptospriosis,Lyme disease
Viral       Rabies, Monkey Pox, Influenza,Hendra
Fungal      Dermatophytosis,
            Aspergillosis,sarcoptes
                    Parasitic
Protozoal   Babesiosis,Leishmaniasis,Toxoplsmosis
Helminth    Toxocariasis, Hydatidosis,Cysticercosis
How is zoonotic disease transmitted ?
Prevention and control of Zoonotic
            diseases
Prevention of zoonotic disease




      Animal oriented

      Human oriented
Animal Hygiene

Animal hygiene is important because it may transmit
disease like ringworm,lyme disease, food poisoning
&Toxoplasmosis.




 Animal cleanliness     Clean Kennel/   Oral cleanliness
                        housing
Vaccinating animals



SPECIES        VACCINES

Dogs      Rabies, Distemper, infectious canine hepatitis,
          leptospirosis, parvovirus, kennel cough (Bordetella
          bronchiseptica and canine parainfluenza virus).


Cats      Feline infectious enteritis, feline leukemia, Chlamydia, cat
          'flu' (feline herpes virus and feline calicivirus


Rabbits   Myxomatosis, viral hemorrhagic disease

Pigeons   Paramyxovirus, pigeon pox ,infectious bronchitis,
Diet                Visit to Vet
Healthy Diet is    • Ensure health of the
healthy immunity     animal
                   • Early diagnosis
Human oriented
Maintaining personnel hygiene
:




    Worms &Germs blog
DF2-bacillus is found in about 8% of healthy dog.
Pasterulla multocida is a common commensual of upper
respiratory tract of dogs (prevalence 12-55%) and cats
(prevalence 52-90%).
Hemophylus,streptococcous,Diphylidium caninum infection may
be transmitted by dogs.
Visit to Doctor




Consult your physician            May be fatal
Role of Veterinarian and Medicos in preventing
               zoonotic disease




      Diagnosis           Surveillance & reporting




       Intersectoral coordination
Endemic zoonotic diseases of public health
  importance in India and its challenges
Disease               Challenge
Rabies                Surveillance
                      Intersectoral coordination
Brucellosis           Strengthening of
Toxoplasmosis         diagnostic facilities
                      Awareness
Cysticercosis
Echinococcos
Food borne zoonoses
Role of Govt agencies and NGOs in
             preventing zoonoses
Registration Pets

IEC activities

Setup of laboratories

Surveillance and information sharing

Intersectoral coordination
Existing Activities for Prevention & Control of
               Zoonotic Disease

•Facilities for Diagnosis ---------- BSL 2, BSL 3, BSL4
•Trained manpower development
•National Programmes/Projects
•Operational guidelines on prevention and control of
various diseases
•Disease surveillance
•Applied Research
Areas need to be strengthened
•Assessment of Magnitude
•Strengthening of diagnostic facilities
•Strengthening intersectoral co-ordination
•Strengthening emergency preparedness
•Strengthening IEC, health education and risk
education
•Strengthening disease surveillance through
IDSP
•Building Public Private Partnership
•Collaborative research
•Collaboration at national, regional and
international level
Special reference to Rabies
Disease Rabies
Acute progressive viral encephalomyelitis which can infect all
mammals and is usually fatal.

Case fatality rate highest of any infectious disease, 60,000 people
die annually.

The disease is caused by viral infection with a Lyssavirus
Worldwide
     more than 98 %
     of the human
     rabies deaths
     follow exposure                           INDIA
                                            Endemic except
     to a rabid dog!
                                           in Lakshadweep
                                           and Andaman.
                                           India accounts for
Although rabies viruses are endemic on     36% of the Global
five of seven continents, the geographic   and 65% of the
distributions of the other lyssaviruses    Asian human
are more localized:                        rabies deaths.
Epidemiology in India
Reservoir
•Major : Dog
•Estimated dog population : 25 million
•Majority : stray, un-owned and unprotected
Animal bites
•Estimated 17.4 million/ yr
•No age or sex predilections
•Higher incidence in children and males
•30-50% PEP given to children 5-14 yrs
After replication in the
                                                 brain
Bite of rabid animal   Transmission             Spread to periphery
Mucus membrane              &                   (salivary glands –
                                                 excretion, other organs)
exposure
Aerosols (bat caves,
                        Pathogenesis
mishandling)

            Brain


                                      Transneuronal
                                  movement toward CNS




                        Site of rabies
                           infection
People at risk should take Pre exposure
               vaccination
Pre exposure prophylaxis of rabies
                       vaccine
                          DAY

      0         7               28            Booster
                                              after 1yr



 Individual who have completed the pre exposure schedule
should have to take 0 and 3 day of vaccine after bite without
                        any serum.

 High exposure risk people should have there neutralizing
         antibody titre checked every 6 months
Principles of Treatment
Wound treatment

(It is a Medical urgency if not Emergency)

Vaccination : Post exposure vaccination (I/M or I/D
route)

Immunoglobulins/anti sera : Category III bite

Advice to patient
Govt initiative in control of Rabies in India
A pilot project was undertaken with the objective of
reducing mortality due to rabies in human .
   • Enhancing awareness
   • Training of health professionals
   • Operationalize ID route in selected centers
   • Strengthen diagnostic capabilities
   • Interface with animal husbandry department
   • Involvement of NGOs and Community

  Future activities:

  • Human component
  • Animal component
Function of Rabies laboratory


(a)Provide laboratory facilities for the diagnosis of
rabies in animal and human post mortem specimens
and antemortem specimens from hydrophobia
cases.

(b) Assessment of anti rabies antibodies in humans
and animals vaccinated with different vaccines
(assessment of vaccine efficacy).
Reservoir                                      Vector     Early clinical
      control                Global                 Control   recognition and
                           Surveillance                            prompt
                                          Diagnostic            intervention
                                           facilities


                 Control of Zoonotic Infections


                                Improved public              Prudent
                  Health
Immunizations     Educat             health               antimicrobial
                   ion           infrastructure Intersectoral usage
                                                 co-ordination
   Approaches to coping with zoonotic infections
The total benefit of having a companion is higher
than the fear of zoonotic disease .

                THANK YOU

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NDWC Chennai 2013 - Prevention & Control of Zoonotic Disease - Dr Shilpi Das

  • 1. Prevention and control of zoonotic disease in companion animals Dr.Shilpi Das Deputy Asst Director National Centre for Disease Control Delhi Dr.Sashanka Sekhar Dutta Chief functionary-JBF-India Trust (Just be friendly)
  • 3. Zoonoses An infectious disease transmissible under natural conditions between vertebrate animals and human beings “A dictionary of Epidemiology” 3rd edition ,1995 editied by John M.Last
  • 4. Importance of Zoonoses 1,415 microbes are infectious for human Of these 868 (61%) are considered zoonotic. 70% of newly recognized pathogens are zoonoses
  • 5. Diseases that can be transmitted from animals to human Category Diseases Bacterial Salmonellosis, Brucellosis, Cat Scratch Disease,Leptospriosis,Lyme disease Viral Rabies, Monkey Pox, Influenza,Hendra Fungal Dermatophytosis, Aspergillosis,sarcoptes Parasitic Protozoal Babesiosis,Leishmaniasis,Toxoplsmosis Helminth Toxocariasis, Hydatidosis,Cysticercosis
  • 6. How is zoonotic disease transmitted ?
  • 7. Prevention and control of Zoonotic diseases
  • 8. Prevention of zoonotic disease Animal oriented Human oriented
  • 9. Animal Hygiene Animal hygiene is important because it may transmit disease like ringworm,lyme disease, food poisoning &Toxoplasmosis. Animal cleanliness Clean Kennel/ Oral cleanliness housing
  • 10. Vaccinating animals SPECIES VACCINES Dogs Rabies, Distemper, infectious canine hepatitis, leptospirosis, parvovirus, kennel cough (Bordetella bronchiseptica and canine parainfluenza virus). Cats Feline infectious enteritis, feline leukemia, Chlamydia, cat 'flu' (feline herpes virus and feline calicivirus Rabbits Myxomatosis, viral hemorrhagic disease Pigeons Paramyxovirus, pigeon pox ,infectious bronchitis,
  • 11. Diet Visit to Vet Healthy Diet is • Ensure health of the healthy immunity animal • Early diagnosis
  • 13. Maintaining personnel hygiene : Worms &Germs blog DF2-bacillus is found in about 8% of healthy dog. Pasterulla multocida is a common commensual of upper respiratory tract of dogs (prevalence 12-55%) and cats (prevalence 52-90%). Hemophylus,streptococcous,Diphylidium caninum infection may be transmitted by dogs.
  • 14. Visit to Doctor Consult your physician May be fatal
  • 15. Role of Veterinarian and Medicos in preventing zoonotic disease Diagnosis Surveillance & reporting Intersectoral coordination
  • 16. Endemic zoonotic diseases of public health importance in India and its challenges Disease Challenge Rabies Surveillance Intersectoral coordination Brucellosis Strengthening of Toxoplasmosis diagnostic facilities Awareness Cysticercosis Echinococcos Food borne zoonoses
  • 17. Role of Govt agencies and NGOs in preventing zoonoses Registration Pets IEC activities Setup of laboratories Surveillance and information sharing Intersectoral coordination
  • 18. Existing Activities for Prevention & Control of Zoonotic Disease •Facilities for Diagnosis ---------- BSL 2, BSL 3, BSL4 •Trained manpower development •National Programmes/Projects •Operational guidelines on prevention and control of various diseases •Disease surveillance •Applied Research
  • 19. Areas need to be strengthened •Assessment of Magnitude •Strengthening of diagnostic facilities •Strengthening intersectoral co-ordination •Strengthening emergency preparedness •Strengthening IEC, health education and risk education •Strengthening disease surveillance through IDSP •Building Public Private Partnership •Collaborative research •Collaboration at national, regional and international level
  • 21. Disease Rabies Acute progressive viral encephalomyelitis which can infect all mammals and is usually fatal. Case fatality rate highest of any infectious disease, 60,000 people die annually. The disease is caused by viral infection with a Lyssavirus
  • 22. Worldwide more than 98 % of the human rabies deaths follow exposure INDIA Endemic except to a rabid dog! in Lakshadweep and Andaman. India accounts for Although rabies viruses are endemic on 36% of the Global five of seven continents, the geographic and 65% of the distributions of the other lyssaviruses Asian human are more localized: rabies deaths.
  • 23. Epidemiology in India Reservoir •Major : Dog •Estimated dog population : 25 million •Majority : stray, un-owned and unprotected Animal bites •Estimated 17.4 million/ yr •No age or sex predilections •Higher incidence in children and males •30-50% PEP given to children 5-14 yrs
  • 24. After replication in the brain Bite of rabid animal Transmission Spread to periphery Mucus membrane & (salivary glands – excretion, other organs) exposure Aerosols (bat caves, Pathogenesis mishandling) Brain Transneuronal movement toward CNS Site of rabies infection
  • 25. People at risk should take Pre exposure vaccination
  • 26. Pre exposure prophylaxis of rabies vaccine DAY 0 7 28 Booster after 1yr Individual who have completed the pre exposure schedule should have to take 0 and 3 day of vaccine after bite without any serum. High exposure risk people should have there neutralizing antibody titre checked every 6 months
  • 27. Principles of Treatment Wound treatment (It is a Medical urgency if not Emergency) Vaccination : Post exposure vaccination (I/M or I/D route) Immunoglobulins/anti sera : Category III bite Advice to patient
  • 28. Govt initiative in control of Rabies in India A pilot project was undertaken with the objective of reducing mortality due to rabies in human . • Enhancing awareness • Training of health professionals • Operationalize ID route in selected centers • Strengthen diagnostic capabilities • Interface with animal husbandry department • Involvement of NGOs and Community Future activities: • Human component • Animal component
  • 29. Function of Rabies laboratory (a)Provide laboratory facilities for the diagnosis of rabies in animal and human post mortem specimens and antemortem specimens from hydrophobia cases. (b) Assessment of anti rabies antibodies in humans and animals vaccinated with different vaccines (assessment of vaccine efficacy).
  • 30. Reservoir Vector Early clinical control Global Control recognition and Surveillance prompt Diagnostic intervention facilities Control of Zoonotic Infections Improved public Prudent Health Immunizations Educat health antimicrobial ion infrastructure Intersectoral usage co-ordination Approaches to coping with zoonotic infections
  • 31. The total benefit of having a companion is higher than the fear of zoonotic disease . THANK YOU