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Bioeast Company Profile.pdf
- 2. Company Overview Subsidiaries Products Certificate & Manufacture Contents 01 02 03 04
- 3. Yinlai Li, CEO • Master degree in Molecular Genetics, Hangzhou Normal University • Serial entrepreneur for 2 IVD upstream material enterprises • Over 10 years experience in IVD upstream industry • “Visionary, pragmatic, generous, reliable, strong in execution” Company Overview A professional developer, manufacturer and solution provider of biomedical core raw materials 300+ Employees 4 Subsidiaries SO13485 & CE Certified 25 Authorized patents $ 3 million+ Annually R&D Cost Financing Series A+ financing (by LYFE capital) Service Science, See the Future
- 4. Subsidiaries • New site in Biopolis, close to research and biotech clients • GMP space for R&D and production of CGT upstream materials • Co-development and CDMO services available • Extending sales network to the Southeast Asia • Over 100 products covering enzymes, cytokines, Ag/Ab • Up to 10kg product per year • Biological enzyme 200L/day • Extraction reagent 1KG/day • Mag-Microbeads 3KG/day • ProteinA chromatography media single batch 500L • Up to 40,000L media yearly • 4 automatic product lines • Assembly up to 2 million POCT products per day Bioeast Acnovia BiogenMicro Aichek Bioeast SG/US 260 m² 2700 m² 6910 m² 8250 m² 3200 m² Hangzhou Suzhou Biopolis > 20000 m² Subsidiaries
- 5. Biomedical Core Raw Materials POCT Integrated Solutions CGT upstream Integrated Solutions Chromatographic Media Solutions POCT Products Ab/Ag, Cytokines IVD Nano Microbeads Chromatographic Media Hangzhou Bioeast Biotech is a global supplier of biomedical core raw materials and integrated solutions, Hangzhou Aichek Medical Technology is the global service supplier of POCT integrated solution. Hangzhou Acnovia Biosystems is the service provider of cell therapy, gene therapy and mRNA overall solution. Suzhou BiogenMicro is a protein purification solution provider, supply Chromatographic products Subsidiaries Subsidiaries
- 7. Enzymes Products Multi molecular enzymes Meet needs of amplification and NGS for various molecular diagnostics Comparison of probe method hot start enzyme qPCR Taq enzyme、UDG enzyme DNA Testing Reverse transcriptase, RI inhibitors RNA testing High-fidelity enzymes, T4 ligase, T4 PNK NGS testing Bsu、SSB、Bst、phi29 Isothermal amplification Highly reversible direct amplification enzyme Sample extraction for Fast Detection Enzyme-derived products and molecular diagnostic auxiliary products Enzyme premixes, molecular enzyme-related kits, and NGS library building kits, etc. Enzyme premixes, molecular enzyme-related kits, and NGS library building kits, etc. Premixes, NGS kits, etc. for research users Lyophilizable/Dryable Products and Services Extraction reagents for viral DNA/RNA, gDNA, RNA, cf-DNA/ ct- DNA, etc. Molecular
- 8. Latex Microspheres & Fluorescence Microspheres Products ST2, AMH, G17, 25-OH-VD and other projects domestic customers market share of about 50% G-17, D-D, SAA program antigens have covered 30% of the national market 27 series ~500 products Cardiac Tumor Other Gastroi ntestin al Inflam mation Drug of abuse Blood clots Respira tory Antigen&Antibody
- 9. GMP Grade Core Material for CGT & mRNA Therapy Products 星汉德生物 Cell Therapy 30+ Prodcts Antibody CD3、CD28 Cytokines CAR-T CAR-NK QC Kit Residue Detection Kit Reference Customers Magnetic beads T、NK Beads Gene Therapy 10+Products Elisa Kit Rapid Test Kit Benzonase Nuclease Reference Customers AAV Antibody
- 10. PrepareTemplate mRNA Synthesis Capping Tailing E.coli Poly(A) Polymerase DNase l Murine RNase Inhibitor Thermostable Inorganic Pyrophosphatese T7 RNA Polymerase BSA I Single stranded capping enzyme mRNA Cap 2 ˊ-O-M ethyltransferase Raw Enzymes Ø The first single-chain capping enzyme system launched in China BSA - Enzyme activity detection T7 RNA Polymerase - transcription effect comparison for different lengths of RNA Cap0 RNA percentage comparison in different temprature 25℃ 30℃ 35℃ 40℃ 45℃ 50℃ vaccinia capping enzyme 51% 78% 93% 94% 91% 19% Single stranded capping enzyme 74% 90% 94% 94% 89% 87% DNase l- DNA digestion Comparison GMP Grade Core Material for CGT & mRNA Therapy Products mRNA Therapy
- 11. Affinity Chromatography Ion Exchange Chromatography Hydrophobic Interaction Chromatography Gel Filtration Chromatography Multimodal Chromatography BiogenMicro supplies Chromatographic Solutions Products The 2nd Generation BiogCapTM Agarose High stiffness & Low Back-Pressure BiogCapTM Large Pore size Agarose
- 12. Aichek is a global POCT integrated solution provider Products l Drug of Abuse Tests( Urine, Oral Fluid, Hair) l Infectious Diseases(HIV, HCV, HbsAg, H.pylori) l Respiratory Diseases(Covid-19, Flu A+B, RSV) l Tumor Markers(FOB, PSA) l Cardiovascular Diseases(CTNI, CK-MB, MYO) l Fertility(HCG, LH) Rapid Test CDMO l Rapid Tests l Immunoturbidity(HbA1c, SAA etc) l Immunofluorescence Tests（Coming soon) l CLIA（Coming soon） l Product design & development l Quality system construction & counseling l Commissioned declare registration l Commercial contract manufacturing service
- 14. Bioeast Workshop Certificate and Manufacture
- 15. Aichek Workshop Sample Pad Handling Machine 1unit Fully-Automatic NC Membrane Dispensing Machine 5units Fully-automatic Conjugate-pad Dispensing Machine 6units Oven 12units ~2400 m2 100,000 Class clean workshop Automatic Cassette Assembly Machine*6units Certificate and Manufacture
- 16. Hello To The World