Created as a key component of the Moross Integrated Cancer Center (MICC) within the Weizmann Institute of Science, the de Picciotto- Lesser Cancer Cell Observatory was founded in Memory of Wolfgang and Ruth Lesser, and established by Michael de Picciotto. The Observatory offers scientists in-depth analysis of cancer cells using advanced imaging technologies, which enables the viewing of live cells in action and at high optical resolutions. De Picciotto has been recorded stating that his contribution to the Cancer Cell Observatory allows him to honour and establish a connection to his beloved grandparents, after his grandfather passed away from pancreatic cancer, as well as to underline his keen attachment to his family roots. The creation of the observatory also comes from his own life-long fascination with science. Michael de Picciotto is keen to follow the future results of the research conducted within the Observatory as the field of cancer cell research continues to advance. It also provides a clear association to the memory of his grandparents and his family. His grandfather, Wolfgang Lesser, a successful businessman and a keen supporter of Israel, was notably a very prominent philanthropist. Today, Israel is known for the high level of scientific research carried out there and the Weizmann Institute of Science is one of the leading multidisciplinary research institutions in both natural and exact sciences not only in Israel but also in the world. In part, de Picciotto is proud to associate his grandparents’ memory with such a prominent institution.