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Pediatric OCD Pharmacotherapy Review
- 1. Pharmacotherapy for Pediatric OCD A Systematic Review
- 9. Clomipramine
- 11. Clomipramine Tremor Fatigue Dizziness Somnolence Dry Mouth 2.3% 32.6% 9.1% 34.8% 13.6% 41.3% 11.4% 45.7% 15.9% 63.0% PBO (N=29) CMI (N=31)
- 12. Clomipramine 0 1 subj. Hepatic Enzyme Inc. 2.3% 13.0% Dyspepsia 2.3% 21.7% Anorexia 2.3% 21.7% Constipation PBO (N=29) CMI (N=31)
- 16. Fluoxetine (1)
- 21. Fluoxetine (2)
- 23. Fluoxetine (2) 4.5% 33.3% Muscle Ache 0% 28.6% Nightmares 4.5% 38.1% Drowsiness 4.5% 33.3% Weight loss 0% 19% Palpitations PBO (N=22) FLX (N=21)
- 27. Paroxetine
- 29. Paroxetine 2% 8% Diarrhea 1% 9% Hostility 1% 9% Decreased appetite 3% 10% Trauma (?) 6% 12% Hyperkinesia PBO N=105 PRX N=98
- 30. Paroxetine 0 1 subj. Suicidal Ideation (?situation) 1% 5% Neurosis (?) 2% 5% Agitation 2% 6% Vomiting 1% 8% Asthenia PBO N=105 PRX N=98
- 34. Fluvoxamine
- 36. Fluvoxamine 15.9% 26.3% Asthenia (mean onset ~20d) 9.5% 29.8% Insomnia (mean onset at 45d) PBO N=63 FLV N=57
- 40. Sertraline (1)
- 42. Sertraline (1) 0% 7% Tremor 2% 13% Agitation 7% 17% Nausea 13% 37% Insomnia PBO N=95 SRT N=92
- 45. Sertraline (2)
- 46. Sertraline (2)
- 48. Sertraline (2) 2% 21% Stomach ache 4% 21% Nausea 4% 12% Motor Overactivity 0% 7% Enuresis 4% 10% Diarrhea 0% 16% Decreased appetite PBO, N=28 SRT, N=56
- 50. Â