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SHEYLA PALACIO - DANIELA PANZA - JESSICA PEREZ - CARLOS QUESADA - CAROLINE RIVERA.
 
 
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[object Object],[object Object],[object Object],[object Object],Group 1 Group 2 Routine care Intensive therapy Both groups followed the same protocol treatment
 
[object Object]
[object Object],[object Object]
[object Object]
Group 1 Group 2 step-up therapy  triple therapy   Ticora 2 Protocol
 
  was designed by a Dutch rheumatologist to look at multiple strategies for treating RA
 
 
 
Comparison of Health Assessment Questionnaire (HAQ) data at 1 year showed that patients receiving initial combination therapy (groups 3 and 4) responded better than those receiving initial monotherapy (groups 1 and 2). However, after 2 years no difference could be seen in functional scores between groups.
 
 
How combination therapy and measurement applies to routine care.
 
 
Approximately 30% of patients in the Swefot trial responded to initial methotrexate and were not randomly assigned to add-on therapy.
 
 
 
 
65 patients  assessed by 1 year.  patient's DAS was assessed  Adalimumab was added for those patients in the monotherapy group who did not respond adequately  3 months started on either methotrexate alone or methotrexate and adalimumab  At 3 months, more patients in the initial combination therapy group than in the initial monotherapy group had low disease activity. However, the difference disappeared at 1 year, at which time about two thirds of the patients in both groups had low disease activity.
[object Object]
TICORA STUDY GUEUPARD STUDY TICORA 2 BEST STUDY SWEFOT STUDY
 
 
 
 
 
 
 
 
 
 
 

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Clinimetrias seminario

  • 1. SHEYLA PALACIO - DANIELA PANZA - JESSICA PEREZ - CARLOS QUESADA - CAROLINE RIVERA.
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  • 16. Group 1 Group 2 step-up therapy triple therapy  Ticora 2 Protocol
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  • 18.   was designed by a Dutch rheumatologist to look at multiple strategies for treating RA
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  • 22. Comparison of Health Assessment Questionnaire (HAQ) data at 1 year showed that patients receiving initial combination therapy (groups 3 and 4) responded better than those receiving initial monotherapy (groups 1 and 2). However, after 2 years no difference could be seen in functional scores between groups.
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  • 25. How combination therapy and measurement applies to routine care.
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  • 28. Approximately 30% of patients in the Swefot trial responded to initial methotrexate and were not randomly assigned to add-on therapy.
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  • 33. 65 patients assessed by 1 year. patient's DAS was assessed Adalimumab was added for those patients in the monotherapy group who did not respond adequately 3 months started on either methotrexate alone or methotrexate and adalimumab At 3 months, more patients in the initial combination therapy group than in the initial monotherapy group had low disease activity. However, the difference disappeared at 1 year, at which time about two thirds of the patients in both groups had low disease activity.
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  • 35. TICORA STUDY GUEUPARD STUDY TICORA 2 BEST STUDY SWEFOT STUDY
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