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Transfusion Medicine Ticu

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Dang Thanh Tuan
Dang Thanh Tuan
Gesundheit & Medizin
1 von 26
Tranfusion Medicine Amanda J. Wheeler, MD Trauma/Critical Care Stanford University Medical Center May 7, 2007
Tranfusion Medicine ,[object Object]
Transfusion Triggers/Indications: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hemoglobin Concentration ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Blood Transfusion Protocol at Stanford Surgery ICU ,[object Object],[object Object],[object Object],[object Object]
Blood Transfusion Protocol at Stanford Surgery ICU ,[object Object]
Massive Transfusion Guidelines ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Other Alternatives: Blood Substitute Slides by Mary-Ann Purtill, MD ,[object Object],[object Object],[object Object],[object Object]
Three primary reasons driving the quest for a substitute for Blood: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Types of Replacement Products ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Oxygen Carrying Solutions ,[object Object],[object Object],[object Object],[object Object]
Oxygen Carrying Solutions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hemoglobin Based Oxygen Carrying Solutions (HBOCs) ,[object Object],[object Object],[object Object],[object Object],Historical Perspective
Problems with HBOCS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Comparison of HBOCs Hemolink PolyHeme Hemopure & Oxyglobin Product Name: 14 hours 24 hours 18-22 hours Half-life: Refrigerated/ RoomTemp Refrigerated Room Temp Storage: 1 year 1 year 3 years Shelf-life: Expired Human RBCs Expired Human RBCs Bovine Hgb Source: Hemosol Northfield Biopure  
Perflourocarbon Oxygen Carriers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Perflourocarbon Oxygen Carriers (cont) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Problems with Perflourocarbons ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antigen Camouflage ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antigen Camouflage ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recombinant Plasma Proteins ,[object Object],[object Object],[object Object],[object Object]
Transgenic Therapeutic Proteins ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Platelet Substitutes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Platelet Substitutes (cont) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Transfusion Medicine Ticu

  • 1. Tranfusion Medicine Amanda J. Wheeler, MD Trauma/Critical Care Stanford University Medical Center May 7, 2007
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  • 17. Comparison of HBOCs Hemolink PolyHeme Hemopure & Oxyglobin Product Name: 14 hours 24 hours 18-22 hours Half-life: Refrigerated/ RoomTemp Refrigerated Room Temp Storage: 1 year 1 year 3 years Shelf-life: Expired Human RBCs Expired Human RBCs Bovine Hgb Source: Hemosol Northfield Biopure  
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