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Ensembl Plants
part of Ensembl Genomes
Dan Bolser, Ensembl Plants project leader,
             HSF 2012/01/26
What is Ensembl Plants?
In the beginning, there was
Ensembl…
What is Ensembl?


         Ensembl

Suite of tools for vertebrate
genomic information
  Genome browser
  Database(s)
  Perl API
What is Ensembl?


         Ensembl

Suite of tools for vertebrate
genomic information
Genome analysis
  Mature code base
  Allows stable pipelines to be
  developed
  Community support
What is Ensembl?


         Ensembl

Suite of tools for vertebrate
genomic information
Genome analysis
Reference data
  Assembly
  Gene build
  Variation, regulation, homology
What is Ensembl?


         Ensembl

Suite of tools for vertebrate
genomic information
Genome analysis
Reference data
Ensembl Genomes


         Ensembl                   Ensembl Genomes

Suite of tools for vertebrate   Applies Ensembl technology to
genomic information             additional species
Genome analysis                 Adopts existing standards
Reference data                  Requires additional time and
                                effort
Ensembl Genomes
Bacteria
Ensembl                        Fungi
Genomes                        Metazoa
Extending Ensembl across the   Plants
taxonomic space
                               Protists

                               Pan-Compara
Why plants?
Food, feed, fuel, pharma, and
future technologies


Crop improvement
Gramene
Ensembl Plants


Current projects (grants)
  Barley
  Wheat
  transPLANT
Future plans
  How to coordinate
  explosive growth?
Current projects


Wheat
  Part of the genome sequencing consortium.
  Money for sequencing / Assembly? / A ‘gene-space’ site.
  One position (starting soon)
Barley
  Part of the genome sequencing consortium.
  Develop resources for the community (EnsBarley).
  One position (starting soon)
Current projects


transPLANT
  A trans-national computer infrastructure for PLANT
  genomic science
  Two positions
    Me + one developer position (currently hiring)
Motivation
  Massive growth in data acquisition
  Many opportunities for crop improvement
  Key parts of plant infrastructure are missing
transPLANT Work Packages


            7. Reference repository for
                genomes
            8. Architecture for plant
                genomic complexity
            9. Archive for plant variation
            10. Linking genotype to
                phenotype
            11. Information retrieval systems
            12. Algorithm extension and
                development
Future…
How to coordinate explosive growth?


  Community annotation      Wiki-style solutions?
  Genomes as a service      SourceForge for genes
    Tools for communities   and genomes?
    rather than a central     Check out
    archive                   Modify
                              Check in your new
                              assembly?
Acknowledgements

Paul Kersey
                   Andy Yates
Dan Staines
                   Jay Humphry
Uma Maheswari
Arnaud Kerhornou
                   All the people I’ve been
Michael Nuhn       nagging with endless
                   emails…
Ensembl Plants: A Guide to Plant Genomic Resources

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Ensembl Plants: A Guide to Plant Genomic Resources

  • 1. Ensembl Plants part of Ensembl Genomes Dan Bolser, Ensembl Plants project leader, HSF 2012/01/26
  • 2. What is Ensembl Plants? In the beginning, there was Ensembl…
  • 3. What is Ensembl? Ensembl Suite of tools for vertebrate genomic information Genome browser Database(s) Perl API
  • 4. What is Ensembl? Ensembl Suite of tools for vertebrate genomic information Genome analysis Mature code base Allows stable pipelines to be developed Community support
  • 5. What is Ensembl? Ensembl Suite of tools for vertebrate genomic information Genome analysis Reference data Assembly Gene build Variation, regulation, homology
  • 6. What is Ensembl? Ensembl Suite of tools for vertebrate genomic information Genome analysis Reference data
  • 7. Ensembl Genomes Ensembl Ensembl Genomes Suite of tools for vertebrate Applies Ensembl technology to genomic information additional species Genome analysis Adopts existing standards Reference data Requires additional time and effort
  • 9. Bacteria Ensembl Fungi Genomes Metazoa Extending Ensembl across the Plants taxonomic space Protists Pan-Compara
  • 10. Why plants? Food, feed, fuel, pharma, and future technologies Crop improvement
  • 11.
  • 13. Ensembl Plants Current projects (grants) Barley Wheat transPLANT Future plans How to coordinate explosive growth?
  • 14. Current projects Wheat Part of the genome sequencing consortium. Money for sequencing / Assembly? / A ‘gene-space’ site. One position (starting soon) Barley Part of the genome sequencing consortium. Develop resources for the community (EnsBarley). One position (starting soon)
  • 15. Current projects transPLANT A trans-national computer infrastructure for PLANT genomic science Two positions Me + one developer position (currently hiring) Motivation Massive growth in data acquisition Many opportunities for crop improvement Key parts of plant infrastructure are missing
  • 16. transPLANT Work Packages 7. Reference repository for genomes 8. Architecture for plant genomic complexity 9. Archive for plant variation 10. Linking genotype to phenotype 11. Information retrieval systems 12. Algorithm extension and development
  • 18. How to coordinate explosive growth? Community annotation Wiki-style solutions? Genomes as a service SourceForge for genes Tools for communities and genomes? rather than a central Check out archive Modify Check in your new assembly?
  • 19. Acknowledgements Paul Kersey Andy Yates Dan Staines Jay Humphry Uma Maheswari Arnaud Kerhornou All the people I’ve been Michael Nuhn nagging with endless emails…

Hinweis der Redaktion

  1. Brief overview of EGPlants, can’t cover much in 15 mins. Audience?
  2. Address the question… Background… (no screen shots).
  3. Launched 1999, initially developed for the human genome project.
  4. Interpreted informatiom
  5. A project based on Ensembl.
  6. Add some quotes…
  7. Future technologies such as fuel and plastics.
  8. NCBI. Rosids vs. Asterids. Variation data for A. thaliana, O. indica, O. sativa, and V. vinifera (grape).
  9. Work with the communities also to develop Ensembl Genomes.
  10. Crop genomes now possible.
  11. Standards!