The next generation of data scientists will be asked to build predictive models that can extract inferences from very large datasets which are unobservable at the surface, even to the best domain experts. Microsoft has access to some truly large data sets, web and search data from the Bing search engine and social data through collaborations with Twitter. In this talk, we show you how a small team of data scientists used this data to build the Bing Predicts engine — a collection of machine learnt predictive models that is beating industry experts at predicting the outcome of events like the Super Bowl, the Oscars, elections and referendums and even breakthroughs in health sciences. The talk will also give a preview of how organizations can adopt a big data mindset to generate and experiment with large data sets and to make amazing predictions using their own data.