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Universidad de Guadalajara
             Centro Universitario Ciencias de la Salud




       Head and Neck
        Pathology
Giovanna Lazcano Sherman
                            Dr. Héctor Manuel Virgen Ayala
     September 2011          Dr. Benjamín Robles Mariscal
Peritonsillar
 Abscess
Peritonsillar Abscess




F. H. Netter. “Atlas de anatomía humana”, Second edition. 2001, Page. 69.
Secondary…

         Acute tonsillitis

  Duct Obstruction Weber
Reason for consultation
Physical Examination




   W. J. Spicer. “Microbiología Medica y Enfermedades
     Infecciosas”, Second edition. 2009, Page. 118.
Diagnosis
Aspiretion   Needle
             Insicion


        Drein the
        abscess
Thyroglossal duct
      cyst
Thyroid Embryology




S. Langman. “Embriología Médica con orientación clínica”, 10ª edition.
                         2007, Page. 281.
In the route
of blind hole,
  can remain
  thyroid
  tissue.        S. Langman. “Embriología Médica con
                 orientación clínica”, 10ª edition. 2007,
                               Page. 281.
F. H. Netter. “Sistema endocríno y enferedades metabólicas”, 1ª
                     edition. 2006, Page. 45.
Differencial Diagnosis




    N. Wood; P.W Woaz.
“Diagnóstico diferencial de las
      lesiones orales y
  maxilofaciales”, 5ª edition.
      1998, Page. 535
Complications
Infections
        Malignancy
       papillary thyroid
          carcinoma
Diagnosis
Aspiration   Needle
             Insicion

Scintigraphy
Scintigraphy




  PLoS Medicine: Perros P (2005) Thyrotoxicosis and Pregnancy. PLoS Med 2(12): e370
doi:10.1371/journal.pmed.0020370 ( http://medicine.plosjournals.org/perlserv/?request=get-
                     document&doi=10.1371/journal.pmed.0020370)
Treatment




                              Sistrunk procedure
L. Torrico. J. Rivero. K. Vasquez “Caso Clínico de Quiste Tirogloso”, recovered
 http://www.univalle.edu/publicaciones/revista_salud/revista06/pagina10.htm
Thyroid
Neoplasms
Histology




A. Stevens; J.Lowe. “Histología Humana”, 3ª edition. 2006, Page. 279.
Thyroid nodules
We have several methods for
 evaluating thyroid nodules
        and classify.

     The interrogation and physical
       examination are so important
Examinations would be useful,
     thyroid hormones,
   ultrasounds, biopsies,
imaging with radio-iodine, x-
       rays, CT, MR.
Thyroid nodules




         R.F. Lick. “Atlas de patología quirúrgica”, 1ª
                            edition. 1981, Page. 47.
Recurrent goiter




R.F. Lick. “Atlas de patología quirúrgica”, 1ª edition. 1981, Page. 49.
Papillary
                   adenocarcinoma




                        85%
R.F. Lick. “Atlas de patología quirúrgica”, 1ª
edition. 1981, Page. 53.
Follicular
        adenocarcinoma
                                  10%


 R.F. Lick. “Atlas de patología
quirúrgica”, 1ª edition. 1981,
           Page. 47.
Follicular
adenocarcinoma




 R.F. Lick. “Atlas de patología
   quirúrgica”, 1ª edition.
       1981, Page. 51.
Medullary carcinoma
                                              7%
Carcinoma that
causes 15% of
  deaths from
 thyroid cancer   Barbara F. Atkinson. “Atlas de Diagnostico
                  Citopatologico”, 2ª edition. 2005, Page.
                                    494.
Medullary carcinoma

     Doesn’t absorb
   radioactive iodine
    and produces
     calcitonin
Undifferentiated
  carcinoma

1%



          R.F. Lick. “Atlas de patología quirúrgica”, 1ª
                             edition. 1981, Page. 53.
Parathyroid
Histology




A. Stevens; J.Lowe. “Histología Humana”, 3ª edition. 2006, Page. 279.
Anatomy




K. L. Moore; A. F. Delley. “Anatomía con orientación
       clínica”, 5ª edition. 2006, Page. 279.
Physiology




            Goldman; Ausiello. “Cecil,
         tratado de medicina interna”,
        23ª edition. 2006, Page. 1113.
Primary
hyperparathyroidism
Arises from 0.1 to 0.3%
    of the population


      most common cause of
           hypercalcemia
Causes
Parathyroid adenoma    83%
Multiple adenoma       6%
Hyperplasia            10%
Carcinoma              1%
Parathyroid adenoma




   R.F. Lick. “Atlas de patología quirúrgica”, 1ª edition. 1981,
                             Page. 51.
90% of all cases responsible
  for hypercalcemia are
    hyperparathyroidism and
                      cancer
Diagnosis

Clinical findings
      and
Laboratory tests
Laboratory tests


calcium          phosphate

   parathyroid hormone
Bone scans
                                             Bone
                                      densitometry

                                          X. Rays

              Recovered
http://intercambiosos.org/showthrea
            d.php?t=4558
Differencial Diagnosis
  Cancer
                         Hyperthyroid
               Thiazide diuretics
       Milk-alkali syndrome
Familial hypocalciuric
hypercalcemia
Secondary
        Terciary
Hyperparathyroidism
Parathyroidectomy   Treatment




                                 Hypoparathyroidism
Recovered http://www.elsevier.es/es/redirect/deprecated?_f=7214&articuloid=13109149
Bibliography
 G. M. Doherty. “Diagnóstico y tratamiento
Quirúrgicos”, thirteenth edition, México; 2006.
      Page. 204-205; 224-240 & 1013.

 L. Goldman; D. Ausiello. “Cecil, tratado de
  medicina interna” 23ª edition; Barcelona;
            España, 2009. Page.

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