The document discusses the long-term effects of exercise on the musculoskeletal, cardiovascular, respiratory, and other body systems. It notes that strength training increases muscle strength through hypertrophy, while endurance training increases mitochondria and fat utilization. Cardiovascular effects include increased stroke volume and elasticity of the heart as well as decreased blood pressure and peripheral resistance. Respiratory changes are decreased ventilatory equivalent and increased maximum ventilation. Other changes involve strengthened tendons, ligaments, bones and cartilage as well as improved flexibility and heat acclimatization. Regular exercise provides benefits like prolonged life, lowered disease risk factors and greater physical reserves.