The Clinical Trials Portal supports improved cancer clinical trial activity data capture, monitoring and reporting across NSW. Find out more about cancer clinical trials in NSW.

1. Clinical Trials Portal
Supporting improved cancer clinical trial activity data capture, monitoring and reporting across NSW
User registration enquiries to clinical.trials@cancerinstitute.org.au
www.cancerinstitute.org.au
Background
The Clinical Trials Portal (Portal) is a
secure online system developed to
provide NSW trial units with a
simple and automated tool to
capture, monitor and report on their
cancer clinical trial activity.
The Portal was designed and
developed by the Cancer Institute
NSW (CINSW) in collaboration with
stakeholders to meet external user
needs and Clinical Trial Program
business requirements.
It was initially targeted at units in
receipt of CINSW funding and is
now being expanded to include all
NSW trial units.
Aim
Improve trial activity data capture
and monitoring in NSW
The Portal provides units with a user
friendly tool to track and monitor
their own trial metrics and
performance.
Improve capability to efficiently
report against a set of Key
Performance Indicators
Capturing a NSW trial activity data
set in one central online system.
This enables the CINSW to report
trial activity and performance against
key clinical trial indicators at both a
State-wide and Local Health District
(LHD) level.
Increase trial awareness and trial
participation
The Portal houses a master list of
cancer trials conducted across NSW.
This allows trial staff, clinicians and
other cancer professionals to access
a searchable list of trials open to
recruitment, to identify potential
trials and participating units for
patient referrals.
Method
External users were involved in both
the development and testing prior to
system implementation. The Portal
was made available to users in
January 2013.
All trial information and activity data
are self reported by users and data
quality maintained by stringent
internal data management
processes.
Registered1
Users
• ClinicalTrial Units
º track and monitor trial
activity and performance
• LHD/Institutions
º evaluate trial performance2
• Cancer Professionals/Clinicians
º boost patient referrals and
trial participation
• Trial Sponsors
º increase trial awareness
1
This is not publically accessible system with
different access levels for confidentiality reasons.
2
Recruitment activity is confidential to each CTU/
LHD/Institution
Results
Functional and efficient trial
activity data capture, monitoring
and report tool supporting local
strategic decision making in cancer
clinical trials. Clinical trial units and
LHDs may utilise the trial activity
data to undertake periodic review of
trial performance:
• by assessing trial milestone dates
• by monitoring recruitment to
target
Improved capability to efficiently
report against a set of clinical trial
key performance indicators as part
of the CINSW Reporting for Better
Cancer Outcomes Program and
other reporting requirements.
A searchable list of cancer clinical
trials conducted in NSW with
recruitment status and site contact
details updated by participating units:
• by sponsors (industry and non-
industry)
• by participating discipline based
clinical trial units
• by trial recruitment status
• by tumour group
Implications
Building a more comprehensive and
accessible state-wide clinical trial
data set and improving reporting
capabilities against performance
indicators, can act as a catalyst to
improved clinical trial operating
models in NSW :
• Improved strategic decision
making within LHDs / Institutions
• Support stakeholders in
identification of gaps and
opportunities in trials
• Inform performance
improvements
The Portal has not yet been fully
realised and with further
enhancements, functionality and
increased usage it can provide even
more opportunities to support a
thriving and robust clinical trial
environment in NSW.
610 interventional
trials
listed on the Master List
152 trained users
with various user functionality
49 clinical trial units
capturing their trial activity
centrally for NSW
1,986 newly enrolled
participants
in 308 recruiting trials in 2013
Increasing knowledge
by capturing accurate and
complete NSW trial activity
Western NSW
Hunter &
New England
Far West
Mid North
North
Murrumbidgee
Southern
NSW
ACT
Unit distribution across
Local Health Districts
Illawarra
Shoalhaven
South
Western
Sydney
Central
Coast
Nepean
Blue
Mountains
Northern
Sydney
Western
Sydney
Sydney
South Eastern
Sydney
Patient Metrics
- Number of pre-screened
- Number of screen failures
- Number of newly enrolled
- Number of active
- Number of follow-up only
Current Recruitment Status
RecruitmentTarget
Trial activity captured by
ClinicalTrial Units
Trial Milestone Dates
- RGO submission
- RGO authorisation
- Recruitment open
- First patient on trial
- Recruitment closed
- Follow-up complete
Principal Investigator
and Key Contact
Julie Ince-Demetriou, Hana Pruskova, Heidi Welberry, Niki Sansey