Where Heartgard Plus can only be used to treat woodworm, hookworm and to prevent heartworms; Simparica Trio is a one-stop-solution to combat all parasites. Know more about their differences with this blog.

1. Simparica Trio VS Heartgard Plus
Pet-parents are well-worn with how the parasites have been havoc in their pets’ life. It seems like there’s
no end when every time they pop up from nowhere. Well, the pet industry indeed has emerged with a
plethora of flea and ticks treatments along with other parasitic treatments. However, to make it easier for
pet-parents, Zoetis has launched a new product called Simaprica Trio that almost covers all the parasites
that haunt your dog. But, its efficiency cannot be measured without comparing the product with existing
popular and trusted products.
Therefore, to give a clear picture of Simaprica Trio for dogs, here’s it has been compared with all-time-
trusted Heartgard Plus for dogs. Let’s get into the details.
Simparica Trio for Dogs

2. Buy Simparica Trio Online!
Simparica Trio is the upgraded form of the renowned Simparica chewable oral treatment. The Zoetis
manufactured product is powerful and potent chewable that works as a multi-spectrum treatment to
protect dogs from heavy flea and tick infestations. Moreover, Simparica Trio aids in the thorough control
of roundworms and adult hookworms. The chews are indicated for the prevention of heartworm.
Heartgard Plus for Dogs
Buy Heartgard Plus At Lowest Price!
Heartgard Plus for dogs is a vet recommended heartworm preventive. A popular monthly treatment
effectively controls heartworm infection and provides total protection against heartworm disease in dogs.
The palatable chews also eliminate hookworm and roundworm from the dog’s system. It safeguards dogs
from harmful heartworm disease and intestinal worms.

3. Simparica Trio v/s Heartgard Plus
Simaparica Trio Heartgard Plus
Active Ingredients Sarolaner, Moxidectin, and
Pyrantel Pamoate
Ivermectin and Pyrantel
Pamoate
How does it work? Sarolaner helps in the
thorough elimination of fleas
and ticks whereas
Moxidection aids in the
prevention of heartworm
disease. On the other hand,
Pyrantel helps in treating and
controlling roundworms and
hookworms.
Ivermectin is effective in
treating the immature form
of heartworms. It controls
the onset of heartworm
disease. The other ingredient
pyrantel treats and prevents
intestinal worms including
roundworms and hookworms
in dogs. The two ingredients
kill parasites through spastic
muscle paralysis and protect
dogs from parasitic danger.
Kills fleas: Yes No
Kills flea before they lay
eggs:
Yes No
Kills ticks: Yes, it kills five types of ticks
including gulf coast ticks,
American dog ticks, Lone star
ticks, deer ticks, and Brown
dog ticks
No
Treats intestinal worms: It effectively treats and
controls intestinal worms like
roundworms and hookworms
in dogs.
Heartgard Plus effectively
eliminates roundworms and
hookworms in dogs.
Prevents heartworms: Simaprica Trio is indicated
for the prevention of
heartworms in dogs.
It assists in killing heartworm
larvae which get transmitted
to your dog by annoying
bloodsuckers thus helping to
prevent heartworm disease.
Palatability: Simaprica Trio is palatable
liver-flavored chew.
Heartgard Plus is a beef-
flavored chewable.
Dosage: Monthly Monthly
Safe for pregnant dogs: The safe use of Simparica
Trio has not been evaluated
in breeding, lactating, or
pregnant dogs. It is suitable
Yes. When used as directed,
Heartgard Plus has a wide
safety margin in all breeds of
dogs, including stud dogs,

4. to use for puppies and dogs
over the age of 8 weeks old
or older.
breeding bitches and puppies
6 weeks or older.
Mode of administration Oral-chewable Oral-chewable
Manufacturer Zoetis Merial/Boehringer Ingelheim
A short video that will help you to understand the difference between Heartgard Plus and Simparica
quickly!
Simparica Trio and Heartgard Plus are two powerful products in the pet market that holds a similarity in
treating intestinal worms and preventing heartworms in dogs. However, it is essential for pet parents to
know that Simaprica Trio is the first monthly chewable to protect dogs against five types of ticks, fleas,
roundworms, hookworms and heartworms, which makes it an all-in-one monthly treatment. Where
Heartgard Plus can only be used to treat woodworm, hookworm and to prevent heartworms. Therefore, if
you are looking for a one-stop-solution to combat all parasites then Simparica Trio is the right pick.
So, what are you waiting for? Both the potent products are available at CanadaVetExpress at discounted
prices.
Reference- https://www.canadavetexpress.com/blog/simparica-trio-vs-heartgard-plus-for-dogs/