Have a look at this presentation to know about the Root Deep which is india's first an advanced hair therapy by Brillare Science. Root Deep‐Absolute Advance III is the thoroughly researched natural cosmetic science against hair fall & decreased hair density. For more information, you can visit www.brillarescience.com .

1. Clinical Backbone

2. 4 Nourishing oils
10 Phytonutrient
extracts
17 Keratin resembling plant
amino acids
Fall Reduction
Root Energizing
Blockage Clearing
Anti Scalp Ageing
Dandruff Removal
Shaft Strengthening
Volumizing
Instant Shine
Smoothening
Frizz Control
10Actions against all 5 concerns of hair fall and decreased
hair density / growth on all 3parts of hair.
The Everything (Hair) Therapy

3. Concern Active Ingredient Efficacy data Formulation details
Fall Reduction Pisum sativum sprout
extract
Increase of growth coefficient (A/T) by 78% in 12 weeks with improvement
in hair and scalp quality by more than 80%
Root Deep Hydroil
Ocimum basilicum hairy
root culture extract
23% increase in dermal papilla cells after 1 month
30.7% decrease in hair fall in 2 months
Root Deep Hydroil
Pterocarpus marsupium
bark extract
Reduction of hair fall in male volunteers with androgenic alopecia:
Frontal zone – 33% in 4 months
Occipital zone – 46% in 4 months
Root Deep Hydroil
Root Deep Shampoo
Root Energizing Plant extracts with
Hexapeptides-11
Around 20% decrease in hair removal due to enlargement of hair bulb after
5 applications
Elementi Puro
Root Recharge synergy
Vanillyl Butyl Ether 66.4% increase in scalp microcirculation(10 Minutes after application)
Increase in IGF-1 production that will lead to increase in Anagen hair density
Elementi Puro
Root Recharge synergy
Blockage Clearing Ocimum basilicum hairy
root culture extract
Upto 80% reduction in sebum as compared to 70% with Finasteride after 72
hours
Root Deep Hydroil
Zinc PCA +65% of Anti 5-α reductase activity compared to positive control in 28 days Elementi Puro
Root Recharge synergy
Anti Scalp Aging Pterocarpus marsupium
bark extract
54% of reduction in glycation after 15 days
78% of free radical inhibition in spot laboratory studies (in tubo)
Root Deep Hydroil
Root Deep Shampoo
Dandruff Removal Piper nigrum fruit extract
and Inga alba bark extract
Effective against dandruff-causing bacterial strain at low MIC
Around 40% reduction in dandruff after 42 days
Around 50% reduction in sebum 42 days
Root Deep Hydroil
Root Deep Shampoo
Root Deep Intenso Fluid
Shaft
Strengthening
Hydrolyzed Pea Protein +4.0 % increase in tensile strength of Hair after each application
+4.3 % increase in Cross section area of Hair after each application
+5.71 % increase in Hair moisture after each application
Root Deep Shampoo
Root Deep Intenso Fluid

4. ++++++++Proven Hair Fall reduction

5. Pisum sativum sprout extractPisum sativum sprout extract++++++ ++++++
Study design I
• Study period of 12 weeks used twice daily
• 20 volunteers of age 21-37
• 17 females with hair in telogen phase > 15%
• 3 males with hair in telogen phase > 20%
Incorporated in
Root Deep Hydroil

6. ResultsResults++++++ Effect on hair fallEffect on hair fall

7. ResultsResults++++++ Reduction of Hair fallReduction of Hair fall

8. ResultsResults++++++ Effect on A/T ratioEffect on A/T ratio

9. ResultsResults++++++ Response from volunteersResponse from volunteers

10. ++++++ ++++++
Study design II
• Study period of 14 days used twice daily
• 10 volunteers of age 46-60
• 4 females
• 6 males
Pisum sativum sprout extractPisum sativum sprout extract
Incorporated in
Root Deep Hydroil

11. ResultsResults++++++ Effect on the expression of dermal papilla signaling moleculesEffect on the expression of dermal papilla signaling molecules
• Noggin – A protein that shortens the telogen phase
• FGF-7 - Fibroblast growth factor – 7 that initiates new anagen phase

12. Ocimum basilicum hairy root culture extractOcimum basilicum hairy root culture extract++++++ ++++++
Biotechnologically derived, holy plant extract with Anti 5-
alpha reductase activity. Provides nourishment to starving
hair roots & promotes fuller, denser hair.
5α reductase is the key target enzyme in the inhibition of
hair loss. Basil root Culture extract inhibit 5α reductase.
Testosterone will not convert into dihydrotestosterone
(DHT) in absence of 5α reductase.
The results showed a clear concentration dependent
inhibition of 5α reductase. Consequently, Basil root
Culture extract was able to reduce hair loss in people with
androgenic alopecia.
Incorporated in
Root Deep Hydroil

13. ResultsResults++++++ Increased proliferation of Dermal papilla cellsIncreased proliferation of Dermal papilla cells

14. Ocimum basilicum hairy root culture extractOcimum basilicum hairy root culture extract++++++ ++++++
• Study period of 2 months used once daily
• 21 volunteers of age 25-67 with daily hair loss
> 100 strains
• 19 females
• 2 males
Study design
Incorporated in
Root Deep Hydroil

15. ResultsResults++++++ ++++++

16. Pterocarpus marsupium bark extractPterocarpus marsupium bark extract++++++ ++++++
• Study period of 6 months used once daily
against placebo
• 40 male volunteers of with androgenic
alopecia
Study design
Incorporated in
Root Deep Hydroil
Root Deep Shampoo

17. ResultsResults++++++ ++++++

18. ++++++++Proven Root Energizing

19. Plant extracts with Hexapeptides-11Plant extracts with Hexapeptides-11++++++ ++++++
• Plant extracts like sugar cane extract, Lemon
fruit extract, Apple fruit extract, green tea
leaf extract along with Hexapetides-11
restores hair and scalp vitality at cellular
level and energizing hair bulb
Incorporated in
Elementi Puro
Root Recharge Synergy

20. Plant extracts with Hexapeptides-11Plant extracts with Hexapeptides-11++++++ ++++++
• Study period of 5 days used once daily
• 15 volunteers of age 30-60 with hair length
of not less than 12 inches
Study design

21. ResultsResults++++++ ++++++

22. ResultsResults++++++ ++++++

23. Vanillyl Butyl EtherVanillyl Butyl Ether++++++ ++++++
• Enhances microcirculation of blood flow
with lesser irritation and warming sensation Incorporated in
Elementi Puro
Root Recharge Synergy

24. ResultsResults++++++ Increase in Blood flowIncrease in Blood flow

25. ResultsResults++++++ Effect on the production of IGF-1Effect on the production of IGF-1

26. ++++++++Proven Blockage Clearing

27. Ocimum basilicum hairy root culture extractOcimum basilicum hairy root culture extract++++++ ++++++
Biotechnologically derived, holy plant extract with Anti 5-
alpha reductase activity. Provides nourishment to starving
hair roots & promotes fuller, denser hair.
5α reductase is the key target enzyme in the inhibition of
hair loss. Basil root Culture extract inhibit 5α reductase.
Testosterone will not convert into dihydrotestosterone
(DHT) in absence of 5α reductase.
The results showed a clear concentration dependent
inhibition of 5α reductase. Consequently, Basil root
Culture extract was able to reduce hair loss in people with
androgenic alopecia.
Incorporated in
Root Deep Hydroil

28. Inhibition of 5α reductase
ResultsResults++++++ ++++++

29. Zinc PCAZinc PCA++++++ ++++++
• Zinc salt of pyrrolidone carboxylic acid, a
double acting complex that optimally allies
the beneficial effects of zinc and L-PCA,
physiological components of the organism.
Incorporated in
Elementi Puro
Root Recharge Synergy

30. Zinc PCAZinc PCA++++++ ++++++

31. Zinc PCAZinc PCA++++++ ++++++
Inhibition of 5α reductase
• Pre-incubation of human Dermal fibroblasts in presence of Zinc PCA / Zinc
chloride and Addition of radioactive (titrated) Testosterone and incubation for 24
hours / preparation of cellHomogenates by sonication and Radioactivity
measurement
• Anti 5-alpha reductase activity of Zinc PCA (+65%) much higher than Zinc chloride
(+45%)
• Intrinsic activity of Zinc PCA greater than equimolar quantity of Zinc chloride.
Study design

32. ResultsResults++++++ ++++++
Inhibition of 5α reductase

33. Zinc PCAZinc PCA++++++ ++++++
Seboregulatory activity
• Sebometric study on 2 groups of 16 volunteers after 28 daily application on the
half forehead with a cream containing 1% Zinc PCA vs Placebo and non-treated
zone
Study design
ResultsResults

34. Zinc PCAZinc PCA++++++ ++++++
Antimicrobial activity
• Minimum Inhibitory Concentration of Zinc PCA was identified and optimized for
various bacterial and fungal strains.
Study design
ResultsResults

35. ++++++++Proven Anti scalp Aging

36. Pterocarpus marsupium bark extractPterocarpus marsupium bark extract++++++ ++++++
• Anti glycation activity
• Against aminoguanidine as positive control
Study design
Incorporated in
Root Deep Hydroil
Root Deep Shampoo
ResultsResults

37. ResultsResults++++++ ++++++
• Anti free radical activity

38. Pterocarpus marsupium bark extractPterocarpus marsupium bark extract++++++ ++++++
• Test on Keratinocytes:
• On the model of UVB induced inflammation against positive control of Aspirin
• Incubation period of 72 hours
Anti-inflammatory effect:
Study design I
ResultsResults

39. Pterocarpus marsupium bark extractPterocarpus marsupium bark extract++++++ ++++++
• Test on Polymorphonuclear neutrophilic granulocytes (PMN):
• On the model of UVB induced inflammation against positive control of Minocyclin
• Incubation period of 24 hours
Anti-inflammatory effect:
Study design II
ResultsResults

40. ++++++++Proven Dandruff Removal

41. Piper nigrum fruit extract and Inga alba bark extractPiper nigrum fruit extract and Inga alba bark extract++++++ ++++++
• Study period of 6 months used once daily
against placebo
• Against Bacterial strains Malassezia globosa
and Malassezia furfur, responsible for dandruff,
inflammation and irritation
• Incubation period of 48 hours
Anti microbial activity:
Study design
Incorporated in
Root Deep Hydroil
Root Deep Shampoo
Root Deep Intenso Fluid
ResultsResults

42. Piper nigrum fruit extract and Inga alba bark extractPiper nigrum fruit extract and Inga alba bark extract++++++ ++++++
• On human keratinocytes on the model of UVB
induced inflammation against positive control
of Aspirin
• Incubation period of 48 hours
Anti inflammatory activity:
Study design
ResultsResults

43. Piper nigrum fruit extract and Inga alba bark extractPiper nigrum fruit extract and Inga alba bark extract++++++ ++++++
• To evaluate the scalp conditions (dandruff, sebum) against a shampoo with 1%
zinc pyrithione, after 4 weeks of treatment and 2 weeks of remanence period
Improvement of Scalp properties:
Study design

44. ResultsResults++++++ ++++++
Reduction in Dandruff:

45. ResultsResults++++++ ++++++
Reduction in Sebum:

46. ResultsResults++++++ ++++++
Response of Volunteers:

47. ++++++++Proven Shaft strengthening

48. Hydrolyzed Pea ProteinHydrolyzed Pea Protein++++++ ++++++
• 17 keratin resembling plant amino acids
• Improves hair strength lost by damages
• Restores hair moisture and prevents dry hair
• Smoothens hair surface
Incorporated in
Root Deep Shampoo
Root Deep Intenso Fluid

49. ResultsResults++++++ ++++++
Tensile strength measurement:

50. ResultsResults++++++ ++++++
Cross-section measurement:

51. ResultsResults++++++ ++++++
Hair moisture measurement:

52. Natural is the most over utilized but perhaps the least specified term in personal care creations.
Whenever you make a choice of using natural products, the question is "how much nature does it
actually hold"? Subtracting the water part, nature score indicates the exact percentage of natural
ingredients in your selected Brillare science product. So the next time when you read our score, count
your nature proximity & be assured of our constant endeavor to keep you as close as possible-to
nature.
When it comes to cleaning, sensitive skin/hair possesses the common phenomena of over sensitivity
towards traditional cleansers.
Let's clean it with sulphate free, biodegradable cleansers.
It's your body & it's your world.
Stand By The Environment.
++++++ ++++++
Personal care cosmetics are formulated with dual purpose of action. One is for the concern specific
efficacy and other is for the wellness feel it imparts on human body and soul. Active score is brillare
research laboratory's conscious effort to formulate the personal care cosmetics which carries higher
percentage of concern specific active ingredients. These active ingredients are carefully combined
with organoleptic advancements in cosmetic base. It brings better efficacy, enhanced nourishment
and greater cosmetic wellness.
The Difference

53. ++++++ ++++++The Difference
Patented#
Anti hair fall and
Hair regrowth promoting
Nature quantified formulations
India first – World first
# Patent pending for deep penetrating micro-emulsion techniques of Hydroil & Root Recharge Synergy