Blossom project management software allows distributed engineering teams at Twitter to focus on their work by providing great integration with communication tools like Hipchat. The document discusses how distributed companies can effectively manage remote work through asynchronous communication over tools like GitHub, online communities, and conferences, ensuring connectivity and security with VPNs and co-working spaces. It also emphasizes using OKRs, dedicated channels for questions, leveraging fewer team members through automation, and choosing tools that automate development tasks and enable remote pairing and reviews.