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THE PHYSICS OF
MRI
NILOTPAL DAS
DEPARTMENT OF BIOMEDICAL ENGINEERING
NETAJI SUBHASH ENGINEERING COLLEGE
WHAT IS MRI?
 Magnetic resonance imaging (MRI) is a noninvasive medical imaging
technique that helps diagnose medical conditions.
 MRI uses a powerful magnetic field, radio frequency pulses and a
computer to produce detailed pictures of organs, soft tissues, bone and
virtually all other internal body structures.
 An X-ray is very effective for showing doctors a broken bone, but if they
want a look at a patient's soft tissue, including organs, ligaments and
the circulatory system, then they'll likely want an MRI. And, another
major advantage of MRI is its ability to image in any plane.
MAGNETIC RESONANCE IMAGING
THE MRI MACHINE MRI OF HUMAN BRAIN
THE FIVE SIMPLE STEPS
 Patient is placed in a magnet.
 Radio wave is sent in
 Radio wave is turned off
 The patient emits a signal
 The emitted signal from the patient is used for reconstruction of the
image
THE PHYSICS OF MRI
 Human body is made of cells, cells are made of various atoms, and
all atoms contain protons in their nucleus.
 Protons carry positive charge and possess spin.
 We know, moving charge is electric current, and electric current
induces magnetic field.
 Thus, proton has its own magnetic field, and act as
tiny bar magnets.
FIRST, THE PATIENT IS PLACED INSIDE
THE MAGNET
 When the protons are placed in an external magnetic field, they
align themselves according to the external magnetic field like a
compass needle aligns itself along the magnetic field of earth.
 The protons may however align in two different ways: parallel or
antiparallel to the external magnetic field.
 These different types of alignments have different energy levels.
Naturally the preferred state of alignment is the
one which requires less energy.
LONGITUDINAL MAGNETIZATION
 Proton pointing in opposite direction cancels each
others magnetic effect in respective direction.
 As there are more protons aligned parallel to the
external magnetic filed, there is a net magnetic
movement aligned with or longitudinal to the
external magnetic field
 In a strong external magnetic field a new magnetic
vector is induced in the patient, who becomes a
magnet himself.
 This new magnetic vector is aligned with the
external magnetic field, and thus called longitudinal
magnetization.
PROTON PRECESSION
 In the presence of an external magnetic field protons
show a certain type of movement called precession,
similar to the ‘wobbling’ movement of a spinning top just
before it is about to stop.
 It is important to know how fast proton precess. The
number of times proton precess per second is called
precession frequency. It Depends upon the strength of
the magnetic field in which protons are placed.
 The precession frequency is calculated using Larmor
Equation:
NEXT, A RADIO WAVE IS SENT TO THE
PATIENT
 The purpose of this RF pulse is to disturb the protons which are
peacefully precessing in alignment with the external magnetic field.
For this we need a RF pulse that can exchange energy with the
protons, a RF pulse with same frequency as the precessing protons.
 Only when the RF pulse and the protons have the same frequency,
can protons pick up some energy from the radio wave, a
phenomenon called resonance (this is where the "resonance" in
magnetic resonance come s from). We can calculate the
frequency of the necessary RF pulse from Larmor Equation.
EFFECT OF RF PULSE
 Some of the protons pick up the energy
and move from lower energy level to
higher energy level, that is, some of the
protons that were previously pointing
along the magnetic field align them
against the magnetic field
(antiparallel). This causes the
longitudinal magnetization to decrease,
as the number of excess protons
aligned along the external magnetic
field decreases
EFFECT OF RF PULSE
 The RF pulse causes the protons to
precess in sync. They now point in
the same direction at the same
time, thus their magnetic forces add
up in the direction they are pointing.
This results in a magnetic vector
pointing to the side to which the
protons precess, that is in the
transverse direction (in the X-Y
plane). This is called the transversal
magnetization.
NEXT, THE RADIO WAVE IS TURNED
OFF
 Before RF pulse there was only longitudinal magnetization.
 After the 90dgr RF pulse there is only transversal magnetization and this is spinning
around
 With time after the removal of RF pulse the transversal magnetization decreases
and longitudinal magnetization increases in spiral motion
OBTAINING MRI SIGNAL FROM THE
PATIENT
 When an antenna is placed near the
tissue, an electric current is set up in the
antenna due to the spiralling movement of
the magnetic vector from the transversal to
longitudinal direction. Due to the spiralling
movement, the magnetic vector gradually
moves away from the antenna and thus
the amplitude of the current induced
reduces gradually. This is called FID signal,
free induction decay.
COMPUTING AND DISPLAY
 The received signal is then fed into a computer and, amazingly, a quarter of a second
later an image appears on the screen.
REFERENCES
 MRI Made Easy by Prof Dr Hans H. Schild; Published by Schering, AG.
 Basic MRI Physics by Evert J. Blink.
 http://science.howstuffworks.com/mri.htm
 https://www.cis.rit.edu/htbooks/mri/inside.htm
 http://en.wikipedia.org/wiki/Physics_of_magnetic_resonance_imagi
ng
THANK YOU
PRESENTED BY:
NILOTPAL DAS

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The Physics of MRI

  • 1. THE PHYSICS OF MRI NILOTPAL DAS DEPARTMENT OF BIOMEDICAL ENGINEERING NETAJI SUBHASH ENGINEERING COLLEGE
  • 2. WHAT IS MRI?  Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique that helps diagnose medical conditions.  MRI uses a powerful magnetic field, radio frequency pulses and a computer to produce detailed pictures of organs, soft tissues, bone and virtually all other internal body structures.  An X-ray is very effective for showing doctors a broken bone, but if they want a look at a patient's soft tissue, including organs, ligaments and the circulatory system, then they'll likely want an MRI. And, another major advantage of MRI is its ability to image in any plane.
  • 3. MAGNETIC RESONANCE IMAGING THE MRI MACHINE MRI OF HUMAN BRAIN
  • 4. THE FIVE SIMPLE STEPS  Patient is placed in a magnet.  Radio wave is sent in  Radio wave is turned off  The patient emits a signal  The emitted signal from the patient is used for reconstruction of the image
  • 5. THE PHYSICS OF MRI  Human body is made of cells, cells are made of various atoms, and all atoms contain protons in their nucleus.  Protons carry positive charge and possess spin.  We know, moving charge is electric current, and electric current induces magnetic field.  Thus, proton has its own magnetic field, and act as tiny bar magnets.
  • 6. FIRST, THE PATIENT IS PLACED INSIDE THE MAGNET  When the protons are placed in an external magnetic field, they align themselves according to the external magnetic field like a compass needle aligns itself along the magnetic field of earth.  The protons may however align in two different ways: parallel or antiparallel to the external magnetic field.  These different types of alignments have different energy levels. Naturally the preferred state of alignment is the one which requires less energy.
  • 7. LONGITUDINAL MAGNETIZATION  Proton pointing in opposite direction cancels each others magnetic effect in respective direction.  As there are more protons aligned parallel to the external magnetic filed, there is a net magnetic movement aligned with or longitudinal to the external magnetic field  In a strong external magnetic field a new magnetic vector is induced in the patient, who becomes a magnet himself.  This new magnetic vector is aligned with the external magnetic field, and thus called longitudinal magnetization.
  • 8. PROTON PRECESSION  In the presence of an external magnetic field protons show a certain type of movement called precession, similar to the ‘wobbling’ movement of a spinning top just before it is about to stop.  It is important to know how fast proton precess. The number of times proton precess per second is called precession frequency. It Depends upon the strength of the magnetic field in which protons are placed.  The precession frequency is calculated using Larmor Equation:
  • 9. NEXT, A RADIO WAVE IS SENT TO THE PATIENT  The purpose of this RF pulse is to disturb the protons which are peacefully precessing in alignment with the external magnetic field. For this we need a RF pulse that can exchange energy with the protons, a RF pulse with same frequency as the precessing protons.  Only when the RF pulse and the protons have the same frequency, can protons pick up some energy from the radio wave, a phenomenon called resonance (this is where the "resonance" in magnetic resonance come s from). We can calculate the frequency of the necessary RF pulse from Larmor Equation.
  • 10. EFFECT OF RF PULSE  Some of the protons pick up the energy and move from lower energy level to higher energy level, that is, some of the protons that were previously pointing along the magnetic field align them against the magnetic field (antiparallel). This causes the longitudinal magnetization to decrease, as the number of excess protons aligned along the external magnetic field decreases
  • 11. EFFECT OF RF PULSE  The RF pulse causes the protons to precess in sync. They now point in the same direction at the same time, thus their magnetic forces add up in the direction they are pointing. This results in a magnetic vector pointing to the side to which the protons precess, that is in the transverse direction (in the X-Y plane). This is called the transversal magnetization.
  • 12. NEXT, THE RADIO WAVE IS TURNED OFF  Before RF pulse there was only longitudinal magnetization.  After the 90dgr RF pulse there is only transversal magnetization and this is spinning around  With time after the removal of RF pulse the transversal magnetization decreases and longitudinal magnetization increases in spiral motion
  • 13. OBTAINING MRI SIGNAL FROM THE PATIENT  When an antenna is placed near the tissue, an electric current is set up in the antenna due to the spiralling movement of the magnetic vector from the transversal to longitudinal direction. Due to the spiralling movement, the magnetic vector gradually moves away from the antenna and thus the amplitude of the current induced reduces gradually. This is called FID signal, free induction decay.
  • 14. COMPUTING AND DISPLAY  The received signal is then fed into a computer and, amazingly, a quarter of a second later an image appears on the screen.
  • 15. REFERENCES  MRI Made Easy by Prof Dr Hans H. Schild; Published by Schering, AG.  Basic MRI Physics by Evert J. Blink.  http://science.howstuffworks.com/mri.htm  https://www.cis.rit.edu/htbooks/mri/inside.htm  http://en.wikipedia.org/wiki/Physics_of_magnetic_resonance_imagi ng