2016 Biotechnician Assistant Credentialing Exam

Florida’s
Secondary
Industrial
Biotechnology
Program &
Biotechnician
Assistant
Credentialing
Exam (BACE)
Lori Wojciechowski
2016 Bio-Link Summer
Fellows Forum

© UF/CERHB© UF/CERHB
Hot Spot for Bioscience Job
Creation
195 JOBS 145 JOBS 220 JOBS
579 JOBS
100 JOBS
45 JOBS
275 JOBS
225 JOBS
90 JOBS
200 JOBS
100 JOBS
94% = Growth in Florida’s biotechnology sector over the past 6 years*
9% = Increase in # of Biotech Companies (2013-2014)
Nearly 80,000 Total Jobs, with 16 Billion Economic Output**
*Source: BioFlorida, Sid Martin Biotechnology Incubator BioDatabase – (Dr. Michael Schmitt)
**Source: Battelle Technology Partnership Practice, The Economic Impact of the U.S. Biopharmaceutical Industry, Report
prepared for PhRMA, July 2013

Florida Biotech Sector
www.bioflorida.com/resource/resmgr/Industry_Data/State_of_the_Industry_Report.pdf
www.enterpriseflorida.com/industries/life-sciences/

Career Opportunities
• Research & Development
• Manufacturing
• Quality Control (QC)
• Quality Assurance (QA)
• Regulatory Affairs
• Facilities
• Business
• Administration

Building the Workforce
Florida Partnership for Industrial
Biotechnology
• Develop & deliver curricula
for industrial biotechnology
(short-course) training
• Ensure programs within
educational institutions are
relevant & meet industry’s
needs & standards
• HS Industrial Biotechnology
Program
– Blended CTE/Academic Credit
– “Equally Rigorous” Science
• Local Articulation Agreements
• Teacher Training/Prep

High School Industrial
Biotechnology I, II, III
• Added to the FL DOE Course Code Directory
(December 2006)
• Comprehensive sequence covering skills used by
industrial, medical, agricultural and research
facilities
– Biotech I & II -Students earn 0.5 each of
Academic (elective science) and CTE credit
– Biotech III earns 1 full CTE credit
– Performance and Sunshine State Standards
(Next Generation) assigned to each benchmark
• Provides multiple career paths
– Articulation into A.S. degree/Certificate
– University
– Entry level employment

Biotech II
#3027020
Transformation
Culture Scale-up
Recombinant Proteins
Production of Proteins
Protein Quantification
Filtration & Purification
ELISA
PAGE
Western/Southern Blot
PCR
Assay Development
Quality Control
Quality Assurance
Regulatory Affairs
Product Marketing
Biotech I
# 3027010
History, Benefits, Careers
Safety Procedures
Solution Preparation
Basic Chemistry
Basic Equipment
Cell Structure & Function
Culturing Microorganisms
Sterile Technique
Experimental Design
DNA Isolation/Analysis
Environmental Monitoring
Data Analysis
Law & Ethics
Documentation
Communication
Biotech III
#8736030
CTE Credit Only
Independent design
and implementation of
student projects,
simulating
employment in a
biotechnology-based
industry and utilizing
industry partners
Program Overview
8736000

Teacher Certification (IBTE)
• District Certification Program – CERHB
– 80 hour (2-week) “Industrial Biotechnology Teacher
Experience” Workshop
– Provides industry experience in the context of the
curriculum, including preparative steps
– Completion of this course earns “district certification”
for existing Biology and Chemistry teachers, enabling
them to teach the CTE components of the program
• Teacher Short Courses
• DNA and Cloning
• Working with Proteins
• Industry Assays
• Applications of PCR
• Core Concepts in Biomanufacturing & Quality Systems

Statewide Articulation:
Secondary to A.S. (Biotechnology)
• POS Grant from US Department of Education’s Office of
Career and Technical and Adult Education (managed
through FL DOE)
• Comparison of secondary standards to postsecondary
Biotechnology course standards
– Syllabi, course descriptions, Florida’s SCNS, Instructor
communications
• Alignment with Industry, Postsecondary, and National
Standards

Career and Professional
Education Act (2007)
Facilitate partnerships between business and
education; to attract, expand, and retain targeted,
high-value industry and sustain knowledge-based
economy
• Improve MS and HS academic performance through
Rigorous & Relevant curricula
• Provide Rigorous and Relevant career-themed
courses
• Articulate to postsecondary coursework and lead to
industry certification

“Biotechnician Assistant”
Credential
Based on foundational concepts and skills required in
biotechnology-based workplace settings
• Written & Practical exam questions/skills
• Aligned w/Academic and Performance Standards
• Industry recognition through BioFlorida
• Accuracy, Alignment of Questions to Standards,
and Representative of Industry needs
– Biopharmaceutical, Diagnostics, Environmental
– Approved by Florida’s Board of Education, Jan., 2012
for statewide articulation (A.S.) Biotechnology
– Manufacturing and Health Science Career Clusters

© Biotility @UF/CERHB© Biotility @UF/CERHB
Biotechnician Assistant
• Distinct from A.S. “Biotechnician”
• Basic lab support
• Prepare solutions, culture media
and equipment for use
• Document data
• Monitor/maintain equipment.
• Assist in facility and equipment
cleaning
• Assist with
experiments/tests/manufacturing
• Assists with Inventory, MSDS
• Salary
• Start out $10.00-$12.00/hour
• High potential for growth

Growth & Dissemination
• Alachua County Santa Fe HS
• Broward County Coconut Creek HS
• Citrus County Crystal River HS*
• Dade County Law Enforcement Officers’
Memorial HS, MAST @ Homestead HS*
• Duval County Mandarin HS
• Hernando County Central HS
• Hillsborough County Middleton HS
• Indian River County Sebastian River HS &
Vero Beach HS
• Lake County Lake Minneola HS
• Madison County Madison County HS
• Manatee County Palmetto HS*
• Marion County North Marion HS, West
Port HS*
• Okaloosa County Ft. Walton Beach HS*
• Orange County Cornerstone Charter
Academy*
• Osceola County Celebration HS*
• Nassau County West Nassau HS*
• Palm Beach County Palm Beach Lakes HS,
Seminole Ridge HS & Spanish River HS
• Pinellas County Countryside HS
• Polk County Lake Gibson HS
• Putnam County Palatka HS
• Santa Rosa County Pace HS
• Seminole County Oviedo HS
• St. Johns County Ponte Vedra HS
• St. Lucie County Treasure Coast HS
• Sumter County Sumter HS
• Volusia County University HS*
• Warsaw Area Career Center* (Warsaw,
IN)
• Anderson HS (Austin, TX)
• Richmond HS* (Richmond, IN)
• Billings Career Center (Billings, MT)
• Approximately 4300 students enrolled in
biotech courses
*PLTW
2016 Districts, 37 Schools, ≈ 650 Students

Partnership with Project Lead
The Way
• PLTW Biomedical Sciences (BMS)
Program
• Foundation Courses
• Principles of the Biomedical Sciences (PBS)
• Human Body Systems (HBS)
• Medical Interventions (MI)
• Capstone Course
• Biomedical Innovation (BI)
• Adopted BACE as PLTW’s Biomedical
Sciences Credentialing Exam

Biotechnician Assistant
Credentialing Exam (BACE)
• Online (“written”) component,
administered at high school
• Approximately 75 questions (one point each); 3
hours allotted
• Practical laboratory component, which
may be proctored at high school or
other approved laboratory
• Practical: Approximately 40-50 questions (100
points total); 3 hours allotted

BACE Written Exam Subjects
CELLS (8%)
• Cells (general)
• Cell Structures & Organelles
• Identifying Cell Structures
• Photosynthesis
CHEMISTRY/BIOCHEMISTRY (42%)
• Bonds
• Cell Respiration
• Chemistry, Molecules & Macromolecules
• DNA Structure & Function
• Enzymes & Reactions
• Periodic Table
• Protein Structure & Function
• Reaction Rates
• Translation (Gene Expression)
GENETICS (5%)
• Genomics
• Mitosis & Chromosomes
• Meiosis
• Ploidy
LABORATORY SKILLS/APPLICATIONS (23%)
• Cell and Tissue Culture
• Electrophoresis
• Microscopy
• Polymerase Chain Reaction (PCR)
• pH
• Restriction Enzymes
• Southern Blotting
• Transformation & Transfection
• Western Blotting & ELISA
RESEARCH & SCIENTIFIC METHOD (12%)
• Experimental Design
• Understanding Scientific Method
• Graphing
GENERAL TOPICS IN BIOTECHNOLOGY (10%)
• Applications
• Benefit to Society
• Biotech Careers
• Ethics
• Historical
• Regulatory
• Workplace

BACE Practical
• Proctored in an approved laboratory by
District-level proctor, or by course teacher
with District-level supervisor present
• Exams and reagent kit are supplied in
advance
• Proctors assess students’ skills based on
supplied rubric in Skills Assessment Form
• Exams, Skills Assessment Form and
students’ work are sent back to Biotility for
scoring

BACE Practical Exam Subjects
APPLIED MATHEMATICS IN BIOTECHNOLOGY
(15%)
• Density
• Graphing
• Beer’s Law
• Standard Curves
• Axis Scaling and Limits
• Plotting Data
BIOTECHNOLOGY SKILLS (49%)
• Autoclaving
• Culturing Organisms
• Aseptic/Sterile Technique
• Electrophoresis
• Liquid Measurement (Macro and Micro)
• pH
• Pipetting (Macro and Micro)
• Serial Dilutions
• Spectrophotometry
LABORATORY EQUIPMENT (12%)
• Identifying Glassware
• Proper Usage:
• Electrophoresis Equipment
• Spectrophotometer
• Micropipettors
• Weighing/Using Balance
PREPARING SOLUTIONS (12%)
• Proper Technique
• Volume/Volume Calculations
• Weight /Volume Calculations
• Molarity Calculations
• Dilutions
WORKPLACE SAFETY & BEHAVIOR (12%)
• Identifying Safety Symbols
• Laboratory Safety Protocols
• Understanding Safety Data Sheets (SDS)
• Personal Protective Equipment (PPE)
• Labeling Samples & Product

BACE Statistics
Year 2012 2013 2014 2015
# Schools 4 7 10 26
# Students 55 100 232 417
Passage Rate 69.1 63.0 68.1 69.0

Grade Level
0
10
20
30
40
50
60
HS Junior HS Senior College Junior
What was your grade level when you took the Biotechnician Assistant Credentialing Exam?

Post-Secondary Plans
0
10
20
30
40
50
60
70
80
90
100
Which of the following best describes your immediate plans for school?

Employment in HS
0
10
20
30
40
50
60
70
80
Not Employed Part-time in bioscience-related
job
Part-time in non-bioscience-
related job
Full-time in bioscience-related job Full-time in non-bioscience-
related job
Current employment status?

Post-Secondary Employment
Plans
0
10
20
30
40
50
60
70
Yes, in bioscience-related job Yes, in non-bioscience-related job No N/A (not attending college)
Do you plan to work while completing your education?

BACE Employment Assistance
0
10
20
30
40
50
60
70
80
Yes No
Do you feel passing the BACE assisted you in gaining employment/promotion?

Practice Exam
0
10
20
30
40
50
60
70
80
90
Yes/Helpful Yes/Not helpful No, but it was available to me No, I wasn't aware of practice exam
Did you have the opportunity to take the BACE Practice exam? Was it helpful?

Thank You
University of Florida
Dr. Richard O. Snyder (PI)
Dr. Mary Jo Koroly
Tamara Mandell
Santa Fe College
Dr. Linda Nichols
Dr. Kelly Gridley
Florida State College Jacksonville
Dr. Kathryn Birmingham
Dr. Kevin Pegg
Indian River State College
Dr. Henri Sue Bynum
Dr. Robin Willoughby
Alachua County School District
Dr. David Edwards
Bill Herschleb
June Camerlengo
Marion County School District
Dee Reedy
Jill Stephens
Palm Beach County School District
Fred Barch
Lyn Slygh
Tom Hession
International Society
for Pharmaceutical Engineers
Beth Potter
Ali Montes
Florida Department of Education
Kathleen Taylor
Loretta Costin
Eric Owens
Banner Center for Career Academies
Dr. Frank Fuller

2016 Biotechnician Assistant Credentialing Exam

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