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The Biochemistry of MemoryThe Biochemistry of Memory
How does new information
turn into memories?
How does new information
turn into memories?
Figure 6.1: Basic Memory ProcessesFigure 6.1: Basic Memory Processes
Levels-of-Processing
Model of Memory
Levels-of-Processing
Model of Memory
• Memory depends on the extent to which
one encodes and processes information
when first received.
– Maintenance Rehearsal: Encode and process
information through repetition.
– Elaborative Rehearsal: Encode and process
information by relating new material to
information already stored in memory.
Other Models of MemoryOther Models of Memory
• Transfer-Appropriate Processing Model:
Memory depends on how well the encoding
process matches up with what is ultimately
retrieved.
• Parallel Distributed Processing (PDP)
Models: New experiences are not only
stored but also change one’s overall
knowledge base.
Figure 6.2: The Three Stages of MemoryFigure 6.2: The Three Stages of Memory
What am I most likely
to remember?
What am I most likely
to remember?
Sensory MemorySensory Memory
• Major function is to hold information long
enough to be processed further.
– Sensory Registers
• Helps us to experience a constant flow of
information, even if that flow is interrupted.
• Selective Attention: Mental resources are
focused on only part of the stimuli around us.
– Remaining sensory memories fade quickly.
Short-Term Memory (STM)Short-Term Memory (STM)
• The part of the memory systems that stores
limited amounts of information for up to
about 18 seconds unless rehearsed.
• Also called working memory because it
helps us to do much of our mental work.
• Encoding in STM is usually, but not
always, acoustic.
Test Your Short Term MemoryTest Your Short Term Memory
9 2 5
Now, recall the numbers
8 6 4 2
Now, recall the numbers
3 7 6 5 4
Now, recall the numbers
6 2 7 4 1 8
Now, recall the numbers
0 4 0 1 4 7 3
Now, recall the numbers
1 9 2 2 3 5 3 0
Now, recall the numbers
4 8 6 8 5 4 3 3 2
Now, recall the numbers
2 5 3 1 9 7 1 7 6 8
Now, recall the numbers
8 5 1 2 9 6 1 9 4 5 0
Now, recall the numbers
9 1 8 5 4 6 9 4 2 9 3 7
Now, recall the numbers
Figure 6.4: Forgetting in Short-Term MemoryFigure 6.4: Forgetting in Short-Term Memory
Peterson, L. R. & Peterson, M. J. (1959). Short-term retention of individual verbal items. Journal of Experimental Psychology, 59, 193-198.
Long-Term Memory (LTM)Long-Term Memory (LTM)
• Part of the memory system whose encoding
and storage capabilities are believed to be
unlimited.
• Placement of information into LTM usually
involves semantic encoding.
A Recall ExperimentA Recall Experiment
Study the following list of words for 30 seconds:
Desk, chalk, pencil, chair, paperclip,
book, eraser, folder, briefcase, essays
Write down as many of the
words from the list as you can,
in any order
How accurate are my memories?How accurate are my memories?
Constructive MemoryConstructive Memory
• Memories are affected by not only what we
perceive, but also by generalized
knowledge about the world.
• Existing knowledge is used to organize new
information as we receive it.
– We fill in gaps in information that we encode
and retrieve.
Constructive Memory and Parallel
Distributed Processing Models
Constructive Memory and Parallel
Distributed Processing Models
• PDP models suggest how semantic and
episodic memories become integrated in
constructive memories.
• PDP networks can produce spontaneous
generalizations.
• Schemas: Mental representations of
categories of objects, events, and people.
Why Do We Forget?Why Do We Forget?
• Decay: The gradual disappearance of the
information from memory.
• Interference: Either the storage or retrieval
of information is impaired by the presence
of other information.
– Proactive Interference: Old information
interferes with learning new information.
– Retroactive Interference: New information
interferes with recall of old information.
How does my brain change
when I store a memory?
How does my brain change
when I store a memory?
The Biochemistry of MemoryThe Biochemistry of Memory
• New experiences alter the functioning of
existing synapses.
– Long-Term Potentiation: The process of
“sensitizing” synapses.
• Stimulation from the environment promotes
the formation of new synapses.
Figure 6.15: Brain Structures Involved in MemoryFigure 6.15: Brain Structures Involved in Memory
Impact of Brain Damage on MemoryImpact of Brain Damage on Memory
• Anterograde Amnesia: Loss of memory for
any event occurring after the injury.
– Often the result of damage to the hippocampus,
nearby parts of the cerebral cortex, and the
thalamus.
• Retrograde Amnesia: Loss of memory for
events prior to some brain injury.
How can I remember
more information?
How can I remember
more information?
MnemonicsMnemonics
• Strategies for putting information into an
organized context in order to remember it
more easily.
– Verbal organization is basis for many
mnemonics.
• Method of Loci: A mnemonic where one
imagines each item to be remembered
occupying a place within a set of familiar
locations.

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The biochemistry of memory

  • 1. Uploaded by Md. Atai Rabby https://plus.google.com/u/0/+AtaiRabby The Biochemistry of MemoryThe Biochemistry of Memory
  • 2. How does new information turn into memories? How does new information turn into memories?
  • 3. Figure 6.1: Basic Memory ProcessesFigure 6.1: Basic Memory Processes
  • 4. Levels-of-Processing Model of Memory Levels-of-Processing Model of Memory • Memory depends on the extent to which one encodes and processes information when first received. – Maintenance Rehearsal: Encode and process information through repetition. – Elaborative Rehearsal: Encode and process information by relating new material to information already stored in memory.
  • 5. Other Models of MemoryOther Models of Memory • Transfer-Appropriate Processing Model: Memory depends on how well the encoding process matches up with what is ultimately retrieved. • Parallel Distributed Processing (PDP) Models: New experiences are not only stored but also change one’s overall knowledge base.
  • 6. Figure 6.2: The Three Stages of MemoryFigure 6.2: The Three Stages of Memory
  • 7. What am I most likely to remember? What am I most likely to remember?
  • 8. Sensory MemorySensory Memory • Major function is to hold information long enough to be processed further. – Sensory Registers • Helps us to experience a constant flow of information, even if that flow is interrupted. • Selective Attention: Mental resources are focused on only part of the stimuli around us. – Remaining sensory memories fade quickly.
  • 9. Short-Term Memory (STM)Short-Term Memory (STM) • The part of the memory systems that stores limited amounts of information for up to about 18 seconds unless rehearsed. • Also called working memory because it helps us to do much of our mental work. • Encoding in STM is usually, but not always, acoustic.
  • 10. Test Your Short Term MemoryTest Your Short Term Memory 9 2 5 Now, recall the numbers 8 6 4 2 Now, recall the numbers 3 7 6 5 4 Now, recall the numbers 6 2 7 4 1 8 Now, recall the numbers 0 4 0 1 4 7 3 Now, recall the numbers 1 9 2 2 3 5 3 0 Now, recall the numbers 4 8 6 8 5 4 3 3 2 Now, recall the numbers 2 5 3 1 9 7 1 7 6 8 Now, recall the numbers 8 5 1 2 9 6 1 9 4 5 0 Now, recall the numbers 9 1 8 5 4 6 9 4 2 9 3 7 Now, recall the numbers
  • 11. Figure 6.4: Forgetting in Short-Term MemoryFigure 6.4: Forgetting in Short-Term Memory Peterson, L. R. & Peterson, M. J. (1959). Short-term retention of individual verbal items. Journal of Experimental Psychology, 59, 193-198.
  • 12. Long-Term Memory (LTM)Long-Term Memory (LTM) • Part of the memory system whose encoding and storage capabilities are believed to be unlimited. • Placement of information into LTM usually involves semantic encoding.
  • 13. A Recall ExperimentA Recall Experiment Study the following list of words for 30 seconds: Desk, chalk, pencil, chair, paperclip, book, eraser, folder, briefcase, essays
  • 14. Write down as many of the words from the list as you can, in any order
  • 15. How accurate are my memories?How accurate are my memories?
  • 16. Constructive MemoryConstructive Memory • Memories are affected by not only what we perceive, but also by generalized knowledge about the world. • Existing knowledge is used to organize new information as we receive it. – We fill in gaps in information that we encode and retrieve.
  • 17. Constructive Memory and Parallel Distributed Processing Models Constructive Memory and Parallel Distributed Processing Models • PDP models suggest how semantic and episodic memories become integrated in constructive memories. • PDP networks can produce spontaneous generalizations. • Schemas: Mental representations of categories of objects, events, and people.
  • 18. Why Do We Forget?Why Do We Forget? • Decay: The gradual disappearance of the information from memory. • Interference: Either the storage or retrieval of information is impaired by the presence of other information. – Proactive Interference: Old information interferes with learning new information. – Retroactive Interference: New information interferes with recall of old information.
  • 19. How does my brain change when I store a memory? How does my brain change when I store a memory?
  • 20. The Biochemistry of MemoryThe Biochemistry of Memory • New experiences alter the functioning of existing synapses. – Long-Term Potentiation: The process of “sensitizing” synapses. • Stimulation from the environment promotes the formation of new synapses.
  • 21. Figure 6.15: Brain Structures Involved in MemoryFigure 6.15: Brain Structures Involved in Memory
  • 22. Impact of Brain Damage on MemoryImpact of Brain Damage on Memory • Anterograde Amnesia: Loss of memory for any event occurring after the injury. – Often the result of damage to the hippocampus, nearby parts of the cerebral cortex, and the thalamus. • Retrograde Amnesia: Loss of memory for events prior to some brain injury.
  • 23. How can I remember more information? How can I remember more information?
  • 24. MnemonicsMnemonics • Strategies for putting information into an organized context in order to remember it more easily. – Verbal organization is basis for many mnemonics. • Method of Loci: A mnemonic where one imagines each item to be remembered occupying a place within a set of familiar locations.