11. Any condition that significantly reduces renal perfusion pressure and causes
a decreased glomerular filtration rate and azotemia* may cause prerenal
kidney failure.
Clinical conditions that may result in prerenal kidney failure include but are
not limited to: extracellular fluid losses secondary to burns, prolonged
vasoconstriction (hypertension), and reduced cardiac output as seen in
patients with shock syndrome or congestive heart failure.
If prerenal failure is identified early and treated correctly, the kidney
dysfunction may be reversible.
If the underlying cause continues to affect renal perfusion, it may lead to
ischemic damage to the nephron and acute tubular necrosis (ATN).
*Azotemia is a medical condition characterized by abnormally high levels of nitrogen-
containing compounds (such as urea, creatinine, various body waste compounds, and
other nitrogen-rich compounds) in the blood.
12. Problems affecting the flow of blood before it
reaches the kidneys
1) Dehydration
vomiting, diarrhea, water pills, or blood
loss.
2) Disruption of blood flow to the kidneys .
*Major surgery with blood loss,
severe injury or burns, or infection in
the bloodstream.
13. * Blockage or narrowing of a blood vessel carrying
blood to the kidneys.
* Heart failure or heart attacks causing low blood flow.
* Liver failure causing changes in hormones that affect blood
flow and pressure to the kidney
14. Actual damage to the nephrons and renal parenchyma characterize
intrarenal failure.
Clinical conditions that result in intrarenal damage can be categorized
under kidney disease or acute tubular necrosis.
ATN is a common type of acute renal failure in the critically ill patient.
The use of nephrotoxic drugs (streptomycin, penicillin, and amphotericin)
in older patients or in individuals with underlying renal insufficiency place
patients at a higher risk of developing ATN.
The risk for ATN is also higher in patients with prolonged prerenal factors.
ATN is a potentially reversible type of renal failure but it may take weeks
or months before adequate renal function returns.
15. Nephrotoxicants may act at different sites in the kidney, resulting in
altered renal function. The site of injury by selected nephrotoxicants
are shown.
16. Post-renal failure is caused by clinical conditions that cause obstruction to
urine flow.
Any problem that stops the excretion of urine may cause this type of ARF.
Common conditions associated with post-renal failure are tumors, benign
prostatic hypertrophy, kidney stones and bladder neck obstruction.
If post-renal failure is untreated it may result in actual nephron damage
and intrarenal failure.
20. K > 5.5 -6
Tall, peaked T’s
Wide QRS
Prolong PR
Diminished P
Prolonged QT
QRS-T merge –
sine wave
21.
22. Problems affecting the movement of urine out of the
kidneys.
a) Kidney stone: usually only on one side.
b) Cancer of the urinary tract organs or structures near
the urinary tract that may obstruct the outflow of urine.
c) Medications.
23. d) Bladder stone.
e) Benign prostate hyper plasia (the most common cause in
men).
f) Blood clot.
g)Bladder cancer.
24.
25. Renal Problems with the kidney itself that prevent proper
filtration of blood or production of urine(25-40%).
Blood vessel diseases
Blood clot in a vessel in the kidneys
Injury to kidney tissue and cells
26. Medical treatment
◦ Fluid and dietary restrictions
◦ Maintain Electrolytes
◦ May need dialysis to jump start renal function
◦ May need to stimulate production of urine with IV
fluids, Dopomine, diuretics, etc.
◦ Hemodialysis
◦ Peritoneal dialysis
◦ Continous renal replacement therapy (CRRT)
◦ Nursing interventions.
27. Introduction-
Chronic kidney disease (CKD), also known as chronic renal disease (CRD),
is a progressive loss in renal function over a period of months or years.
Chronic kidney disease is diagnosed as a result of screening of people
known to be at risk of kidney problems, such as those with high blood
pressure or diabetes and those with a blood relative with chronic kidney
disease.
It is differentiated from acute kidney disease in that the reduction in kidney
function must be present for over 3 months.
Chronic kidney disease is identified by a blood test for creatinine. Higher
levels of creatinine indicate a lower glomerular filtration rate and as a result
a decreased capability of the kidneys to excrete waste products.
28. Causes of chronic kidney disease (CKD) include the following:
Diabetic kidney disease.
Hypertension.
Vascular disease (Angina & MI).
Glomerular disease (primary or secondary).
Cystic kidney diseases.
Tubulointerstitial disease ( nephritis affecting the interstitium of the kidneys)
Urinary tract obstruction or dysfunction
Recurrent kidney stone disease
Congenital (birth) defects of the kidney or bladder
Unrecovered acute kidney injury
29. Tiredness
Weakness
Not sleeping well
Less desire to eat than usual
Nausea
Itching
Shortness of breath
Altered taste
Altered mental state
30. Although chronic kidney disease cannot be cured, it is
possible to slow the damage to the kidney in most patients.
Doctor may recommend any of the following:
Controlling protein in the urine by restricting the amount of
protein in the diet or medication.
Taking ACE inhibitors or angiotensin II receptor antagonists to
slow the progression to chronic renal failure.
Reducing the use of and the dosages of drugs that may be
toxic to the kidneys.
Managing the complications of chronic renal disease such as
fluid overload, high blood phosphate or potassium levels, low
blood level of calcium, and anemia.
31.
32.
33.
34. There are 3 types of dialysis
Hemodialysis, Dialysis of soluble substances and
water from the blood by diffusion through a
semipermeable membrane; separation of cellular
elements and colloids from soluble
substances is
achieved by pore
size in the
membrane and
rates of
diffusion.
35.
36.
37. Lowering high blood pressure.
Controlling blood sugar and lipid levels.
Staying hydrated.
Controlling salt in the diet.
Quitting smoking.
Undergoing dialysis, a medical process that cleans the blood.
Having a kidney transplant.
Counseling for you and your family about dialysis and/or
transplant options.
38. To help reduce your chance of chronic kidney failure, take the following
steps:
Get a physical exam every year that includes a urine test to monitor your
kidney's health.
Do not smoke. Stop smoking if you are a smoker.
Maintain a healthy weight.
Drink water and other fluids to stay hydrated.
People who have diabetes, previously known kidney disease, high blood
pressure, or are over the age of 60 should be screened regularly for kidney
disease.
People with a family history of kidney disease should also be screened
regularly.
39. Glomerulo nephritis
e.g, Streptococcal bacterial infections may damage the
glomeruli.
Acute interstitial nephritis
1) Medications such as antibiotics, anti-inflammatory
medicines (for example, aspirin, brufen), and water pills .
2) infections and immune-related diseases such as lupus ,
leukemia, lymphoma, and sarcoidosis.
42. Causes include shock (decreased blood supply to the
kidneys), drugs (especially antibiotics)
and chemotherapy agents, toxins and poisons, and
dyes used in certain kinds of x-rays.
Accidents, injuries
complications from surgeries (eg.Heart-bypass
surgery)
Polycystic kidney.
produce less erythropoietin
43. RISK FACTORS
Advanced age
Blockages in the blood vessels in your arms or legs
Diabetes
High blood pressure
Heart failure
Kidney diseases
Liver disease
44. Symptoms
Vomiting and/or diarrhea, which may lead to dehydration.
Nausea.
Weight loss.
Nocturnal urination.
pale urine.
Less frequent urination, or in smaller amounts than usual,
with dark coloured urine
45. Haematuria.
Pressure, or difficulty urinating.
Itching.
Bone damage.
Non-union in broken bones.
Muscle cramps (caused by low levels of calcium which
can cause hypocalcaemia).:
Abnormal heart rhythms.
Muscle paralysis.
46. Swelling of the legs, ankles, feet, face and/or hands.
Shortness of breath due to extra fluid on the lungs
Pain in the back or side
Feeling tired and/or weak.
Memory problems.
Difficulty concentrating.
Dizziness.
Low blood pressure.
47. Other symptoms include
Anorexia
Pruritus
Seizures (if blood urea nitrogen level is very high)
Shortness of breath (if volume overload is present).
Decrease osmolality(A measurement of urine concentration
that depends on the number of particles dissolved in it).
Increase urinary sodium.
Pericarditis.
Pericardial effusion.
Pleural effusion.
Decrease calcium and bicarbonate.
Defect in platelet functionings
49. Diagnosis
History collection.
Physical examination.
1 Asterixis and myoclonus
2 Peripheral edema (if volume overload is present)
3 Pulmonary rales (if volume overload is
present)
4 Elevated right atrial pressure (if volume overload is
present)
50. Identification of precipitating cause.
Serum creatinine and BUN level .(n 7-18mg/dl)
Serum electrolytes.
Urine analysis.
Renal bladder ultra sound.
Renal scan.
CT scans and MRI scan (to identify lesion and masses)
The urine will be examined under a microscope.
biopsy
51. Medical and Pharmacological Treatment
correcting fluid and electrolyte balance.
Correct dehydration.
Correct dehydration.
Keeps other body systems working properly
Furosemide, Torsemide, ethacrynic acid
calcium gluconate
Sodium bicarbonate
dialysis
52. NUTRITIONAL THERAPY
Provide protein diet.
Calori requirements are met with high carbo-hydrate meals
(carbo-hydrates have a protein-sparing effect.
Foods and fluid containing potassium or phosphorous (banana,
coffee) are restricted.
Patient may require parenteral nutrition.
53. Prevention
A careful history(nephrotoxic antibiotic agent
aminoglycosides, gentamicin, tobramicine, etc.)
blood tests and urinalysis
Drink enough fluids
Difficulties urinating or blood in the urine should prompt a
visit
Treat hypotension promptly.
Prevent and treat infections promptly.
Pay special attention to wound, burns and other precursors of
sepsis.
54. COMPLICATIONS
ARF can affect the entire body
Infection
Hyperkalaemia, Hyperphosphataemia, hyponatraemia
water overload
Pericarditis
Pulmonary oedema.
55. Reduced level of consciousness.
Immune deficiency.
NURSING MANAGEMENT
Excess fluid volume related to decreased Glomerular filtration
rate and sodium retention
Risk for infection related to alterations in the immune system
and host defenses
Imbalanced nutrition: less than body requirements
56. Risk for injury related to GI bleeding
Sleep pattern disturbances related to disease condition
Providing skin care
Providing support
Patient Teaching and Home Healthcare Guidelines
conclusion