Anomalies of female reproductive system (Embryology) -uterus -uterine tube -ovary -vagina

1. Anomalies of Female
Reproductive System
MARYAM JAMILAH BINTI ABDUL HAMID
082013100002
IMS BANGALORE

2. LEARNING OUTCOME
• Describe the normal formation of female
reproductive system; paramesonephric duct &
mesonephros
• Students should aware the anomalies of:-
– Ovary
– Uterine tubes
– Uterus
– Vagina
– External genitalia

3. Development of
female genitalia

4. Paramesonephric duct lies lateral to the
mesonephric ducts in the cranial part of
the nephrogenic cord

5. Invagination of
the coelomic
epithelium to
form
paramesonephric
ducts.
The invagination
takes place at the
lateral most part
of the coelomic
epithelium.

6. Partially fused part: fundus of the uterus
Unfused part: uterine tube
*Thickness of myometrium increases. (Myometrium
comes form the surrounding mesoderm)

7. A: lower end of utero-vaginal canal comes in contact with the dorsal wall of
urogenital sinus.
B: Endodermal cells proliferates and form two swellings; sinovaginal bulbs
C:Vaginal plate is formed; mesoderm + endoderm
D: Canalization of vaginal plate

8. • The coelomic epithelium- medial side of
mesonephros thickened & forms genital ridge
• Sex/medullary cords proliferate from this
germinal epithelium & grow into underlying
mesoderm
• Primordial germ cells (from yolk sac migrate
& give rise to oocytes)
• Sex cords broken up into small masses. The
cells of each mass surround one primordial
germ cell/oocyte to form primordial follicle.

10. B
A
C

14. OVARY
• Absent on one or both sides
• Duplicated
• Descend into the inguinal canal or labium
majus
• Adrenal or thyroid tissue present in the ovary
• Contains cells capable of differentiating into
various tissues; bone, cartilage and hair.
– The growth of these cell rests can give rise to
teratoma

15. Ovary in inguinal
canal
Teratoma

16. UTERINE TUBES
• Absent, on one or both sides.
• Partially, or completely, duplicated on one or
both sides.
• Atresia of the tubes.

17. UTERUS
• Completely, or partially, duplicated.
– Complete duplication = uterus didelphys
• Lumen may be partially, or completely,
subdivided by a septum
• Absent of uterus
• One half of the uterus may be absent,
unicornuate uterus
• Uterus may remain rudimentary
• Atresia of the lumen either in the body or cervix

19. A. Uterus duplex unicollis. B. Uterus duplex with double vagina. C. Uterus
didelphys. D. Uterus septus with single vagina. E. Uterus subseptus. F. Uterus
arcuatus. G. Uterus unicornis with rudimentary contralateral hemiuterus.

21. VAGINA
• Duplicated vagina; associated with duplicated
uterus
• Lumen subdivided longitudinally, or
transversely by a septum
• Absent of vagina
• Imperforate hymen
• Rectovaginal fistula
• Vesicovaginal fistula

23. EXTERNAL GENITALIA
• Absent, bifid or double clitoris
• Enlarged clitoris in case of hermaphroditism
and congenital adrenal hyperplasia
• Labia minora may show partial fusion
• Urethra open on the anterior wall of the
vagina

25. REFERENCES
• INDERBIR SINGH, G P PAL, Human Embryology,
8th Edition
• http://www.nylawyer.net/new-york-personal-
injury/medical-malpractice-attorney/
• http://www.glowm.com/resources/glowm/cd
/pages/v1/v1c004.html
• http://www.afrjpaedsurg.org/viewimage.asp?i
mg=AfrJPaediatrSurg_2011_8_2_215_86066_f
1.jpg

26. THANK YOU
FELLOWS !