SlideShare ist ein Scribd-Unternehmen logo
1 von 1
Downloaden Sie, um offline zu lesen
6. You are studying a mutation that is associated with a gene that is implicated in increased
susceptibility to an early onset dementia known as the Foscoe Fever. Many of the patients who
are diagnosed with Foscoe Fever have a SNP where an adenine has been substituted for a
thymine. The mutation creates a new restriction site (5'-AGATCT-3') for the restriction enzyme
BgIll in the regulatory region of the gene encoding Yosef kinase 1. Outline a strategy using the
hybridization techniques discussed in class where you can distinguish individuals who have
inherited this mutation from individuals who have not inherited the mutation. The arrow in the
enclosed figure shows the position of the restriction site created by the mutation. Be complete,
but concise, in the description of your experimental strategy.

Weitere ähnliche Inhalte

Mehr von atc71jaipur

9.6 Computer Fraud and Abuse Techniques. Match the computer f.pdf
 9.6 Computer Fraud and Abuse Techniques. Match the computer f.pdf 9.6 Computer Fraud and Abuse Techniques. Match the computer f.pdf
9.6 Computer Fraud and Abuse Techniques. Match the computer f.pdf
atc71jaipur
 
9.5 hs-Doubly-linked Lists - listTraverse Description In this assignm.pdf
 9.5 hs-Doubly-linked Lists - listTraverse Description In this assignm.pdf 9.5 hs-Doubly-linked Lists - listTraverse Description In this assignm.pdf
9.5 hs-Doubly-linked Lists - listTraverse Description In this assignm.pdf
atc71jaipur
 
9.4 Computer Fraud and Abuse Techniques. Match the Internet-relat.pdf
 9.4 Computer Fraud and Abuse Techniques. Match the Internet-relat.pdf 9.4 Computer Fraud and Abuse Techniques. Match the Internet-relat.pdf
9.4 Computer Fraud and Abuse Techniques. Match the Internet-relat.pdf
atc71jaipur
 
9. Private solutions to correct for externalities Consider the follow.pdf
 9. Private solutions to correct for externalities Consider the follow.pdf 9. Private solutions to correct for externalities Consider the follow.pdf
9. Private solutions to correct for externalities Consider the follow.pdf
atc71jaipur
 

Mehr von atc71jaipur (19)

7. In Josef Toths famous diagram (below), why is water rising (again.pdf
 7. In Josef Toths famous diagram (below), why is water rising (again.pdf 7. In Josef Toths famous diagram (below), why is water rising (again.pdf
7. In Josef Toths famous diagram (below), why is water rising (again.pdf
 
6. Bar eye in Drosophila is an X-linked characteristic in which bar e.pdf
 6. Bar eye in Drosophila is an X-linked characteristic in which bar e.pdf 6. Bar eye in Drosophila is an X-linked characteristic in which bar e.pdf
6. Bar eye in Drosophila is an X-linked characteristic in which bar e.pdf
 
8) (Essay) Answer the following questions about Veblen (please provid.pdf
 8) (Essay) Answer the following questions about Veblen (please provid.pdf 8) (Essay) Answer the following questions about Veblen (please provid.pdf
8) (Essay) Answer the following questions about Veblen (please provid.pdf
 
7. Which of the following statements about the U.S. Census is incorre.pdf
 7. Which of the following statements about the U.S. Census is incorre.pdf 7. Which of the following statements about the U.S. Census is incorre.pdf
7. Which of the following statements about the U.S. Census is incorre.pdf
 
A manufacturing company that produces a single product has provided t.pdf
 A manufacturing company that produces a single product has provided t.pdf A manufacturing company that produces a single product has provided t.pdf
A manufacturing company that produces a single product has provided t.pdf
 
A hypothetical population consists of eight individuals ages 13,14,17.pdf
 A hypothetical population consists of eight individuals ages 13,14,17.pdf A hypothetical population consists of eight individuals ages 13,14,17.pdf
A hypothetical population consists of eight individuals ages 13,14,17.pdf
 
A European call option on a non-dividend-paying stock has a market pr.pdf
 A European call option on a non-dividend-paying stock has a market pr.pdf A European call option on a non-dividend-paying stock has a market pr.pdf
A European call option on a non-dividend-paying stock has a market pr.pdf
 
A company based in the United Kingdom has an Italian subsidiary. The .pdf
 A company based in the United Kingdom has an Italian subsidiary. The .pdf A company based in the United Kingdom has an Italian subsidiary. The .pdf
A company based in the United Kingdom has an Italian subsidiary. The .pdf
 
A contractors project being analyzed by PERT has an estimated time f.pdf
 A contractors project being analyzed by PERT has an estimated time f.pdf A contractors project being analyzed by PERT has an estimated time f.pdf
A contractors project being analyzed by PERT has an estimated time f.pdf
 
8. A series of mutant strains (af) of a particular mold are not able .pdf
 8. A series of mutant strains (af) of a particular mold are not able .pdf 8. A series of mutant strains (af) of a particular mold are not able .pdf
8. A series of mutant strains (af) of a particular mold are not able .pdf
 
6. Let X1,X2,�,Xn be iid RVs with mean and finite variance. What is .pdf
 6. Let X1,X2,�,Xn be iid RVs with mean  and finite variance. What is .pdf 6. Let X1,X2,�,Xn be iid RVs with mean  and finite variance. What is .pdf
6. Let X1,X2,�,Xn be iid RVs with mean and finite variance. What is .pdf
 
A basic assumption of activity-based costing (ABC) is that All manufa.pdf
 A basic assumption of activity-based costing (ABC) is that All manufa.pdf A basic assumption of activity-based costing (ABC) is that All manufa.pdf
A basic assumption of activity-based costing (ABC) is that All manufa.pdf
 
9.6 Computer Fraud and Abuse Techniques. Match the computer f.pdf
 9.6 Computer Fraud and Abuse Techniques. Match the computer f.pdf 9.6 Computer Fraud and Abuse Techniques. Match the computer f.pdf
9.6 Computer Fraud and Abuse Techniques. Match the computer f.pdf
 
A fibers can inhibit transmission of painful stimuli by activating o.pdf
 A  fibers can inhibit transmission of painful stimuli by activating o.pdf A  fibers can inhibit transmission of painful stimuli by activating o.pdf
A fibers can inhibit transmission of painful stimuli by activating o.pdf
 
9.5 hs-Doubly-linked Lists - listTraverse Description In this assignm.pdf
 9.5 hs-Doubly-linked Lists - listTraverse Description In this assignm.pdf 9.5 hs-Doubly-linked Lists - listTraverse Description In this assignm.pdf
9.5 hs-Doubly-linked Lists - listTraverse Description In this assignm.pdf
 
9.4 Computer Fraud and Abuse Techniques. Match the Internet-relat.pdf
 9.4 Computer Fraud and Abuse Techniques. Match the Internet-relat.pdf 9.4 Computer Fraud and Abuse Techniques. Match the Internet-relat.pdf
9.4 Computer Fraud and Abuse Techniques. Match the Internet-relat.pdf
 
9. Private solutions to correct for externalities Consider the follow.pdf
 9. Private solutions to correct for externalities Consider the follow.pdf 9. Private solutions to correct for externalities Consider the follow.pdf
9. Private solutions to correct for externalities Consider the follow.pdf
 
9. In Darcys Law; Q=KiA Explain in simple words what each of the let.pdf
 9. In Darcys Law; Q=KiA Explain in simple words what each of the let.pdf 9. In Darcys Law; Q=KiA Explain in simple words what each of the let.pdf
9. In Darcys Law; Q=KiA Explain in simple words what each of the let.pdf
 
9. Information about the cause of death listed on a death certificate.pdf
 9. Information about the cause of death listed on a death certificate.pdf 9. Information about the cause of death listed on a death certificate.pdf
9. Information about the cause of death listed on a death certificate.pdf
 

Kürzlich hochgeladen

Activity 01 - Artificial Culture (1).pdf
Activity 01 - Artificial Culture (1).pdfActivity 01 - Artificial Culture (1).pdf
Activity 01 - Artificial Culture (1).pdf
ciinovamais
 
1029 - Danh muc Sach Giao Khoa 10 . pdf
1029 -  Danh muc Sach Giao Khoa 10 . pdf1029 -  Danh muc Sach Giao Khoa 10 . pdf
1029 - Danh muc Sach Giao Khoa 10 . pdf
QucHHunhnh
 

Kürzlich hochgeladen (20)

Holdier Curriculum Vitae (April 2024).pdf
Holdier Curriculum Vitae (April 2024).pdfHoldier Curriculum Vitae (April 2024).pdf
Holdier Curriculum Vitae (April 2024).pdf
 
microwave assisted reaction. General introduction
microwave assisted reaction. General introductionmicrowave assisted reaction. General introduction
microwave assisted reaction. General introduction
 
Activity 01 - Artificial Culture (1).pdf
Activity 01 - Artificial Culture (1).pdfActivity 01 - Artificial Culture (1).pdf
Activity 01 - Artificial Culture (1).pdf
 
TỔNG ÔN TẬP THI VÀO LỚP 10 MÔN TIẾNG ANH NĂM HỌC 2023 - 2024 CÓ ĐÁP ÁN (NGỮ Â...
TỔNG ÔN TẬP THI VÀO LỚP 10 MÔN TIẾNG ANH NĂM HỌC 2023 - 2024 CÓ ĐÁP ÁN (NGỮ Â...TỔNG ÔN TẬP THI VÀO LỚP 10 MÔN TIẾNG ANH NĂM HỌC 2023 - 2024 CÓ ĐÁP ÁN (NGỮ Â...
TỔNG ÔN TẬP THI VÀO LỚP 10 MÔN TIẾNG ANH NĂM HỌC 2023 - 2024 CÓ ĐÁP ÁN (NGỮ Â...
 
ICT Role in 21st Century Education & its Challenges.pptx
ICT Role in 21st Century Education & its Challenges.pptxICT Role in 21st Century Education & its Challenges.pptx
ICT Role in 21st Century Education & its Challenges.pptx
 
Ecological Succession. ( ECOSYSTEM, B. Pharmacy, 1st Year, Sem-II, Environmen...
Ecological Succession. ( ECOSYSTEM, B. Pharmacy, 1st Year, Sem-II, Environmen...Ecological Succession. ( ECOSYSTEM, B. Pharmacy, 1st Year, Sem-II, Environmen...
Ecological Succession. ( ECOSYSTEM, B. Pharmacy, 1st Year, Sem-II, Environmen...
 
1029 - Danh muc Sach Giao Khoa 10 . pdf
1029 -  Danh muc Sach Giao Khoa 10 . pdf1029 -  Danh muc Sach Giao Khoa 10 . pdf
1029 - Danh muc Sach Giao Khoa 10 . pdf
 
On National Teacher Day, meet the 2024-25 Kenan Fellows
On National Teacher Day, meet the 2024-25 Kenan FellowsOn National Teacher Day, meet the 2024-25 Kenan Fellows
On National Teacher Day, meet the 2024-25 Kenan Fellows
 
Asian American Pacific Islander Month DDSD 2024.pptx
Asian American Pacific Islander Month DDSD 2024.pptxAsian American Pacific Islander Month DDSD 2024.pptx
Asian American Pacific Islander Month DDSD 2024.pptx
 
Mehran University Newsletter Vol-X, Issue-I, 2024
Mehran University Newsletter Vol-X, Issue-I, 2024Mehran University Newsletter Vol-X, Issue-I, 2024
Mehran University Newsletter Vol-X, Issue-I, 2024
 
ICT role in 21st century education and it's challenges.
ICT role in 21st century education and it's challenges.ICT role in 21st century education and it's challenges.
ICT role in 21st century education and it's challenges.
 
Python Notes for mca i year students osmania university.docx
Python Notes for mca i year students osmania university.docxPython Notes for mca i year students osmania university.docx
Python Notes for mca i year students osmania university.docx
 
PROCESS RECORDING FORMAT.docx
PROCESS      RECORDING        FORMAT.docxPROCESS      RECORDING        FORMAT.docx
PROCESS RECORDING FORMAT.docx
 
Unit-IV; Professional Sales Representative (PSR).pptx
Unit-IV; Professional Sales Representative (PSR).pptxUnit-IV; Professional Sales Representative (PSR).pptx
Unit-IV; Professional Sales Representative (PSR).pptx
 
Grant Readiness 101 TechSoup and Remy Consulting
Grant Readiness 101 TechSoup and Remy ConsultingGrant Readiness 101 TechSoup and Remy Consulting
Grant Readiness 101 TechSoup and Remy Consulting
 
Application orientated numerical on hev.ppt
Application orientated numerical on hev.pptApplication orientated numerical on hev.ppt
Application orientated numerical on hev.ppt
 
Class 11th Physics NEET formula sheet pdf
Class 11th Physics NEET formula sheet pdfClass 11th Physics NEET formula sheet pdf
Class 11th Physics NEET formula sheet pdf
 
Micro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdfMicro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdf
 
Measures of Dispersion and Variability: Range, QD, AD and SD
Measures of Dispersion and Variability: Range, QD, AD and SDMeasures of Dispersion and Variability: Range, QD, AD and SD
Measures of Dispersion and Variability: Range, QD, AD and SD
 
How to Give a Domain for a Field in Odoo 17
How to Give a Domain for a Field in Odoo 17How to Give a Domain for a Field in Odoo 17
How to Give a Domain for a Field in Odoo 17
 

6. You are studying a mutation that is associated with a gene that is.pdf

  • 1. 6. You are studying a mutation that is associated with a gene that is implicated in increased susceptibility to an early onset dementia known as the Foscoe Fever. Many of the patients who are diagnosed with Foscoe Fever have a SNP where an adenine has been substituted for a thymine. The mutation creates a new restriction site (5'-AGATCT-3') for the restriction enzyme BgIll in the regulatory region of the gene encoding Yosef kinase 1. Outline a strategy using the hybridization techniques discussed in class where you can distinguish individuals who have inherited this mutation from individuals who have not inherited the mutation. The arrow in the enclosed figure shows the position of the restriction site created by the mutation. Be complete, but concise, in the description of your experimental strategy.