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Prasit Chanarat

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Erythropoiesis ,[object Object],[object Object],[object Object],[object Object],[object Object]

Blood Forming Organs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Blood Forming Organs (cont.) ,[object Object],[object Object],[object Object],[object Object]

Extrusion Polychromasia Reticulocytes Erythrocytes

Erythropoiesis Mechanism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Regulation of Erythropoiesis ,[object Object],[object Object],[object Object],[object Object],[object Object]

Erythropoietin (Epo) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Factors Effecting Erythropoiesis ,[object Object],[object Object],[object Object]

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Hematopoiesis is the process by which blood cells are formed. It occurs primarily in the bone marrow, which is a spongy tissue found within the cavities of certain bones, such as the sternum, ribs, pelvis, and long bones. Hematopoiesis involves the differentiation and proliferation of hematopoietic stem cells (HSCs) into various types of blood cells. Differentiation and Lineage Commitment: HSCs can differentiate into two main lineages: the myeloid lineage and the lymphoid lineage. Myeloid lineage: Gives rise to red blood cells (erythrocytes), platelets (thrombocytes), and white blood cells (leukocytes) such as granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Lymphoid lineage: Gives rise to lymphocytes, including T cells, B cells, and natural killer (NK) cells. Proliferation and Maturation: Once committed to a specific lineage, progenitor cells undergo proliferation and differentiation into mature blood cells. This process is tightly regulated by various growth factors, cytokines, and hormones. Erythropoiesis: The process of erythrocyte (red blood cell) production. Thrombopoiesis: The process of platelet production. Granulopoiesis: The process of granulocyte (neutrophil, eosinophil, basophil) production. Monocytopoiesis: The process of monocyte production. Lymphopoiesis: The process of lymphocyte production. Regulation: Hematopoiesis is tightly regulated by various factors, including: Growth factors and cytokines such as erythropoietin (EPO), thrombopoietin (TPO), granulocyte colony-stimulating factor (G-CSF), and interleukins. Hormones such as cortisol, thyroid hormones, and sex hormones. Microenvironmental signals within the bone marrow niche. Migration and Circulation: Once matured, blood cells are released into the bloodstream and circulate throughout the body, performing their respective functions. Red blood cells carry oxygen to tissues, white blood cells participate in the immune response, and platelets are involved in blood clotting.

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Rbc

1. Peripheral Blood

2. Whole Blood

3. Hemopoiesis

4. Erythroid Lineage Myeloid Lineage

6. Erythron Erythropoiesis

9. Blood Forming Organs

10. Stages of Erythron

11.

12. E2 E1 E3 E4 E5 E3

13. Extrusion Polychromasia Reticulocytes Erythrocytes

14.

15. Erythropoiesis Mechanism

16. Characteristic of Erythron

17. Bone Marrow Structure

18. Bone Marrow Section

19. Bone Marrow Contour

20. Normal Red Blood Cells

21. Functional Blood Cells

22.

23. Regulation of Erythropoiesis

24.

25. Molecule of Erythropoietin

26.

Rbc

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