2. Introduction
Indications
Contraindications
Preparation
Technique
Interpretation of physiological values and waveforms
Complications
3.
4. Indications
Diagnostic:
Differentiation among causes of shock
Differentiation between mechanisms of pulmonary edema
Evaluation of pulmonary hypertension
Diagnosis of pericardial tamponade
Diagnosis of right to left intracardiac shunts
Unexplained dyspnea
5. Therapeutic:
Management of perioperative patients with unstable cardiac status
Management of complicated myocardial infarction
Management of patients following cardiac surgery/high risk surgery
Management of severe preecclampsia
Guide to pharmacologic therapy
Burns/ Renal Failure/ Heart failure/Sepsis/ Decompensated cirrhosis
Assess response to pulmonary hypertension specific therapy
6. Contraindication:
Absolute:
Tricuspid and pulmonary valvular
stenosis
Tetrology of fallot
Infection at insertion site
Presence of RV assist device
Insertion during CPB
Lack of consent
Relative:
Coagulopathy
Thrombocytopenia
Electrolyte disturbances
(K/Mg/Na/Ca)
Severe Pulmonary HTN
7. Preparation
Patient has to be monitored with continuous ECG throughout the procedure, in
supine position regardless of the approach
Aseptic precautions must be employed
Cautions should be taken while cannulating via IJV/ Subclavian vein
10. Catheters:
The standard PAC has 7.0,7.5 or 8.0 Fr
circumference and in 110cm in length with distances
marked at 10cm intervals.
DOUBLE LUMEN- for ballon inflation and PA
pressure
TRIPLE LUMEN- above 2 + RA pressure
QUADRUPLE LUMEN- above 3 + THERMISTOR for
thermodilution {CO measurement}
FIVE LUMEN –additional lumen for drug infusion
11.
12. Technique
1. Aseptic precautions undertaken
2. Local infiltration done
3. Check balloon integrity by inflating with 1.5ml of air
4. Check lumens patency by flushing with saline 0.9%
5. Cover catheter with sterile sleeve provided
6. Cannulate vein with Seldinger technique
7. Place sheath
8. Pass catheter through sheath with tip curved towards the heart
13. 9. Once tip of catheter passed through introducer sheath inflate balloon at level of
right ventricle
10. The progress of the catheter through right atrium and ventricle into pulmonary
artery and wedge position can be monitored by changes in pressure trace
11. After acquiring wedge pressure deflate balloon
16. Physiological Measurements:
Direct measurements of the following can be
obtained from an accurately placed pulmonary artery
catheter(PAC)
Central Venous Pressure(CVP)
Right sided intracardiac pressures(RA/V)
Pulmonary artery pressure(Pap)
Pulmonary artery occlusion pressure (PAOP)
Cardiac Output
Mixed Venous Oxygen Saturation(SvO2)
17. Indirect measurements that are possible:
Systemic Vascular Resistance
Pulmonary Vascular Resistance
Cardiac Index
Stroke volume index
Oxygen delivery
Oxygen uptake
18. Calculation of Cardiac Output:
Thermodilution versus Ficks method
•Thermodilution: Add an indicator substance (5ml of dextrose or
saline) that is cooler than blood. Indicator in injected through the
proximal port of the PA catheter and mixes with the blood in the
RV. The mixing lowers the temperature of the flowing blood which
is carried to the distal thermistor port. The thermistor records the
temperature change and electronically displays a temperature/time
curve. The area under the curve is inversely proportional to the
flow rate in the pulmonary artery which equals the cardiac output in
absence of intracardiac shunt
-sources of error with thermodilution are seen with
tricuspid regurgitation and intracardiac shunts
19. Fick’s Method
General principle: the release or uptake of a substance by
an organ equals the product of the bloodflow through
that organ times the difference of arteriovenous
concentrations of that substance.
CO= O2 consumption (ml/min)
------------------------------------------------------------
---
arterial O2 content(PCWP)-mixed venous (PA) O2
content
O2 consumption varies according to individual, by age
and sex. Usually estimated as being 250mL for a 70kg
male. Generally estimated at 130mL x BSA
Blood O2 content=% saturation X Hb x 1.39 ml O2/gm
Hb
Errors: assumptions of O2 consumption, wont work at all
with intracardiac shunts. But works better with TR
23. Pulmonary arterial occlusion pressure:
Once catheter tip has reached PA, it should be advanced until
PAOP is identified by decrease in pressure and change in
waveform
The balloon should then be deflated and PA tracing should
reappear
If PCOP tracing persists catheter should be withdrawn with
definitive PA tracing obtained
24. Final position of the catheter within PA must be such that PCOP tracing is
obtained whenever 75-100% of 1.5ml maximum volume of balloon is
insufflated.
If < 1ml of air is injected and PAOP is seen then it is overwedged needs to be
withdrawn
If after maximal inflation fails to result in PCOP tracing or after 2-3 seconds delay
too proximal – advanced with balloon inflated
25. PCWP/PAOP interprets Left atrial pressures
more importantly – LVEDP
PAEDP ~ PAOP ~ PVP ~ LAP ~ LVEDP
Best measured in
Supine position
At end of expiration
Zone 3 (most dependent region)
Normal PCWP- 6-15 mmHg ; Mean :9mmHg
27. Decreased PCWP:
Hypovolemia
Obstructive shock due to large pulmonary embolus
Abnormal waveforms
Large a waves:
MS
LV systolic /diastolic function
LV volume overload
MI
Large v waves - MR
29. Related to insertion of PAC:
Arrhythmias (most common- Ventricular/ RBBB)
Misplacement
Knotting
Myocardial/valve/vessel rupture
Related to maintenance and use of PAC:
Pulmonary artery perforation
Thromboembolism
Infection