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H177 Midterm Dezoysa
1. HC 177: Biotech & Art Neuro Imaging Art and Manipulation Madushka Yohan De Zoysa Neuroscience
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4. Context and Precedents An EEG measures the electric activity of certain parts of the brain based upon the firing of neurons. fMRIs display which areas of the brain are more active by mapping changes in blood flow in the brain. As a result, brain areas that are engaged in neural activity experience an increase in metabolism and blood flow, which shows up as a bright region on the fMRI. Transcranial magnetic stimulators use changing magnetic fields to induce weak electric currents in the brain. This works to manipulate the electrical activity already present in the brain.
5. Project Proposal - Artistic Aspect Visual Portion EEGs reveal neural activity in specific areas of the brain based on electrical signaling. Integrating all these wavelengths of activity has the potential to create a changing map of global brain function, much like what is found in fMRIs. Different portions of the brain will light up based on what the subject is doing/thinking at that given moment. Audio Portion Using an electroencephalophone, it is possible to make audible what is normally never considered to make sound [1] . One can combining brainwave sounds with a real-time map of the changing brain activity map to create a unique audiovisual piece unique to every individual who performs it.
6. Project Proposal - Diagnostic Aspect The functional EEG activity map will prove invaluable as a diagnostic tool. Patients who are incapable of remaining still (Parkinson’s and epilepsy patients) will be able to finally image their brain activity and gain a better sense of where their problem lies. [2] Additionally, patients with neuromuscular disorders can understand how their neurons misfire when attempting to move a muscle. Other neurological anomalies, such as phantom limb syndrome (an example of synaesthesia) can be examined.
7. Project Proposal - Clinical Aspect Current transcranial magnetic stimulators have the same low spatial resolution problem as current fMRIs. As mentioned before, they use affect electric currents through magnetic fields created by two large loops of metal. This is what creates the low spatial resolution. By making these metal coils smaller and attaching them to an EEG-type cap, it is possible to selectively stimulate parts of the brain. Can be used to manage seizures as they develop as well as enabling brain function recovery in stroke patients.