ADAS-AF: LGE-MRI Analysis of Fibrosis in the Atrial Wall, Rosa Maria Figueras et al. Poster at Atrial Signals Conference, Valencia (Spain), 2017

1. Follow-up and revisionIntra-intervention EP guide
ADAS-AF:
LGE-MRI Analysis of Fibrosis in the Atrial Wall
Rosa M. Figueras i Ventura1, Xavier Planes1, Lluís Mont2, Luis Serra1
1 Galgo Medical S.L. (Barcelona, Catalonia, Spain)
2 UFA (Unitat de Fibril·lació Auricular de l’Hospital Clínic), Hospital Clínic, Universitat de Barcelona &
IDIBAPS, Barcelona, Catalonia,
ADAS-AF: software tool designed to bring atrial fibrosis information extracted from LGE-MRI into current clinical practice
Late Gadolinium
Enhancement
3D MRI
Characterize substrate structure
“Non-Invasive Mapping™”
Pre-interventional
treatment planning
Intra-intervention EP
guide
Follow-up and procedure
revision
Pre-interventional treatment planning
Isolation of
fibrotic
patches
Closure of gaps
in re-do ablation
procedures
Sphericity
and volume
computation
Fibrosis
quantification
Fibrosis
quantification and
gap visualization
Joint EAM and
MRI
visualization
ADAS 3D
ADAS-AF features and tools
Side by side comparison of MRI and
EAM or MRI1 and MRI2
Export 3D atrial model to main
navigation systems
Semi-automatic 3D atrial fibrosis map
generation
Semi-automatic atrial
wall delineation and
3D model creation
Automatic
quantification of
anatomical features
CARTO®
(Biosense Webster)
EnsiteTM
(Abbott)
MRI-EAM
MRI pre – MRI post
ADAS-AF in clinical papers
Authors Title Publication year Achievement
Benito, E.M.; Andreu,
D.: Mont, L.;
Berruezo, A.
Correlation between functional electrical gaps identified
by ultrahigh-density mapping and by late gadolinium
enhancement cardiac magnetic resonance in repeat
atrial fibrillation procedure
Heart Rhythm Case Reports
3(5): 282-285
2017 Anatomical gap localization performed with
ADAS-AF. Match with electrical gap.
Benito, E.M.;
Carlosena-Remirez,
A.; Guasch, E.; et al.
Left atrial fibrosis quantification by late gadolinium-
enhanced magnetic resonance: a new method to
standardize the thresholds for reproducibility
EP Europace 19(8): 1272-
1279
2017 Analysis of 10 healthy patients to derive
thresholds for atrial fibrosis in LGE-MRI.
Pontecorboli, G.;
Figueras i Ventura,
R.M.; Carlosena, A.;
et al.
Use of delayed-enhancement magnetic resonance
imaging for fibrosis detection in the atria: a review
EP Europace 19(2): 180-189 2017 Review of several methods to analyze atrial
fibrosis.
Andreu, D.; Gomez-
Pulido, F.; Calvo, M.;
et al.
Contact force threshold for permanent lesion formation
in atrial fibrillation ablation: A cardiac magnetic
resonance–based study to detect ablation gaps
Heart Rhythm 13(1): 37-45 2016 Study to derive minimum force required to
achieve anatomical isolation of the veins.
Bisbal, F.; Andreu, D.;
Berruezo, A.
Simplified mapping and ablation of a scar-related atrial
tachycardia using magnetic resonance imaging tissue
characterization
EP Europace 17(2): 186 2015 Case report showing that fibrosis information
obtained thanks to ADAS-AF helps to ablate
atrial tachycardia.
Bisbal, F.; Guiu, E.;
Cabanas-Grandío, P.;
et al.
CMR-Guided Approach to Localize and Ablate Gaps in
Repeat AF Ablation Procedure
JACC: Cardiovascular
Imaging 7(7): 653-663
2014 Study that shows that LGE-MRI can provide
useful information for gap ablation in repeat AF
procedures.