2. What is respiration?
The act or process of inhaling and exhaling;
breathing. Also called ventilation.
The oxidative process occurring within living
cells by which the chemical energy of organic
molecules is released in a series of metabolic
steps involving the consumption of oxygen and
the liberation of carbon dioxide and water.
3. What does happen when respiration
occurs?
The oxygen which is in taken in respiration . It
helps in the process of catabolism
Catabolism: complex food molecules to small
particles and get converted to acetyl coA
4.
5. Respiration chain
The energy librated during the oxidation of food
molecules is made available with in
mitochondria as reducing equivalents (NADH
and FADH2)
Mitochondria contains the respiratory chain
which collects and transport reducing equivalents
directing them to their final reaction with oxygen
to form water
6.
7. The passage of electrons in ETC is associated with the
loss of free energy ,this free energy is utilized to
generate ATP.
this respiration chain occurs in the mitochondria in
the inner membrane( matrix, Cristal )
8. Components of respiration chain
The inner mitochondria membrane can be disrupted
into 5 distinct respiratory or enzyme complex
denoted as complex I, II, III, IV and V .
. NADH-Q oxidoreductase, succinate-Q reductase,
Q-cytochrome c oxidoreductase, and
cytochrome c oxidase are also called Complex I, II,
III, and IV, respectively
9. And complex V is responsible for ATP synthesis
Pyruvate and alpha –ketoglutarate dehydrogenase
and feS are other components
15. Complex III
ubiquinone - ubiquinone ox
while cyt C gets reduced
Also contains cytochromes b
proton pump 4H+
Adds to gradient
8 H+ / NADH
4 H+ / FADH2
16.
17. Complex IV
reduction of oxygen
cytochrome oxidase
cyt a+a3 red ---> oxidized state
oxygen ---> water
2 H+ + 2 e- + ½ O2 -- 2 H2O
transfers e- one at a time to oxygen
Pumps 2H+ out
Total of 10 H+ / NADH
Total of 6 H+ / FADH2
18.
19. Totals
Proton gradient created as electrons transferred to
oxygen forming water
10 H+ / NADH
6 H+ / FADH2
