This presentation contains prescribed drugs indication,machanism of action,contraindication and side effect of the following drugs: 1.Sulbutamol(oral) 2.Calcium Carbonate (Elemental) + Vitamin D 3.Atrovastatin calcium 4.Vildagliptin and Metformin Hydrochloride 5.Cefuroxime Axetil + Clavulanic Acid

1. PRESCRIBED DRUG
Submitted To Submitted By
Nazia Haque Md. Abu Bakar Siddique
Assistant Professor Dibalok Debnath
Department of Pharmacy Alfi Shahrin
East West University Rezwana Sultana
Sadia Afroz

2.  NAME OF THE DRUG:
 Brand Name: Brodil
 Generic Name: Salbutamol
(oral)
 MANUFACTURER:
 ACI Limited
 INDICATION:
 Asthma
 Chronic Bronchitis
 Emphysema

3. MECHANISM OF ACTION:

4.  CONTRAINDICATION:
 Hypersensitivity to Salbutamol
 During Pregnancy
 During Lactation
 SIDE EFFECTS:
 Tremor
 Tachycardia, tenseness, headaches
 Angina, nausea, vomiting

5.  NAME OF THE DRUG
 Brand Name: Ultracal-D
 Generic Name: Calcium Carbonate
(Elemental) + Vitamin D
 MANUFACTURER
Peoples Pharma Ltd
 INDICATION
 low blood Calcium levels
 Osteoporosis
 Osteomalacia
 Rickets
 Tetany
 Hypoparathyroidism
 Pre-eclampsia during
pregnancy
 Supplement for;
 Pregnancy & lactation
 Elderly patients
 Inadequate intake of Calcium
in childhood

6. MECHANISM OF ACTION:
Calcium Carbonate: Vitamine D:
Maintains Calcium
homeostasis
Helps in the formation
of bone mass
Maximum elemental
calcium for adsorption
Ensures maximum
calcium absorption
Decrease bone
resorption
Promotes bone
mineralization

7.  CONTRAINDICATIONS:
 Hypersensitivity to the product
 Hypercalciuria
 Osteoporosis
 SIDE EFFECTS:
 Flatulence
 Diarrhea
 Constipation
 Upper GI discomfort
 Hypercalciuria
 Hypercalcemia

8.  NAME OF THE DRUG:
 Brand name: Stacor
 Generic name: Atrovastatin
Calcium
 MANUFACTURER:
Unimed & Unihealth
Manufacturers Ltd
 INDICATION:
o Hypercholesterolemia
o Elevated serum TG levels
o Primary
dysbetalipoproteinemia
o LDL apheresis

9. MECHANISM OF ACTION:
Inhibits HMG-CoA
reductase and cholesterol
synthesis
Lowers plasma cholesterol
and lipoprotein levels
Increases hepatic LDL
receptors
Reduces LDL production
Increase in LDL receptor
Changes in circulating
LDL particles

10.  CONTRAINDICATIONS:
 Hypersensitivity
 Active liver disease
 Serum transaminases
 Pregnancy
 Breast-feeding
 SIDE EFFECTS:
 Rhabdomyolysis
 Confusion
 Fever
 Dark urine
 Drowsiness
 Loss of appetite
 Jaundice

11.  NAME OF THE DRUG:
 Brand Name: Dialiptin-M
 Generic: Vildagliptin and
Metformin Hydrochloride
 MANUFACTURER:
DRUG INTERNATIONAL LTD
 INDICATION:
improve glycaemic control in
patients with type 2 diabetes
mellitus

12. MECHANISM OF ACTION:
Vildagliptin: Metformin:

13. CONTRAINDICATION
 Hypersensitivity
 Renal Impairment: Creatinine clearance
 acute or chronic metabolic acidosis, including diabetic ketoacidosis
 Patients with type 1 diabetes
 SIDE EFFECTS
 Lactic acidosis can occur due to Metformin
 hepatic dysfunction
Some common side effects :
tremor headache
fatigue dizziness

14. NAME OF THE DRUG
 Brand Name: Famiclav 500
 Generic Name: Cefuroxime
Axetil + Clavulanic Acid
 MANUFACTURER
ACME Laboratories LTD
INDICATION
 Pharyngitis
 Acute bacterial otitis media
 Pneumonia
 Skin and Skin-Structure
Infections
 Urinary tract infections
 Bone and Joint infections
 Gonorrhea
 Meningitis

15. Mechanism of Action
Cefuroxime: Clavulanic acid:
Binds with PBPs in bacterial
cell wall
Inhibits the transpeptidation
step of peptidoglycan
synthesis
Inhibits baterial cell wall
biosynthesis
Destroys the cell wall
Bacterial death
Binds with beta
lactamase
Highly active complex
Binds with amino acid of
beta lactamase
Inactive the beta
lactamase enzyme
Protection against
resistence pathogens

16.  Contraindication:
 Allergy to Cefuroxime and Clavulanic acid or to the cephalosporin
group of antibiotics
 Side Effect:
 Nausea
 Vomiting
 Diarrhea
 Abdominal discomfort