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Human metapneumovirus

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Dr. Saad Saleh Al Ani
Dr. Saad Saleh Al Ani

What is human metapneumovirus ,features,presentation ,diagnosis ,treatment and prevention

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Human Metapneumovirus Prof. Dr. Saad S Al Ani Senior Pediatric Consultant Head of Pediatric Department Khorfakkan Hospital Sharjah ,UAE [email_address]
Human Metapneumovirus (hMPV) ,[object Object],Williams JV, Wang CK, Yang CF, et al :  The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience.   J Infect Dis   2006; 193:387-395
Cont. ,[object Object],[object Object],( 1)van den Hoogen BG, de Jong JC, Groen J, et al: A newly discovered human pneumovirus isolated from young children with respiratory tract disease.   Nat Med  2001; 7:719-724.
Cont. ,[object Object],[object Object],( 1)van den Hoogen BG, de Jong JC, Groen J, et al: A newly discovered human pneumovirus isolated from young children with respiratory tract disease.   Nat Med  2001; 7:719-724.
Cont. ,[object Object],[object Object],[object Object],van den Hoogen BG, de Jong JC, Groen J, et al :  A newly discovered human pneumovirus isolated from young children with respiratory tract disease .   Nat Med   2001; 7:719-724.
Cont. ,[object Object],[object Object],[object Object],[object Object],[object Object],Osterhaus A, Fouchier R :  Human metapneumovirus in the community.   Lancet   2003; 361:890-891.
Cont. ,[object Object],[object Object],[object Object],[object Object],[object Object],Williams JV, Tollefson SJ, Heymann PW, et al :  Human metapneumovirus infection in children hospitalized for wheezing.   J Allergy Clin Immunol   2005; 115:1311-1312
Bar in the image represents 10 nm. Glycoprotein spikes are visible in viral membrane and extruded nucleocapsid is visible below Human Metapneumovirus
Epidemiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cont. ,[object Object],[object Object],[object Object],[object Object]
Clinical Manifestations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Noyola DE, Alpuche - Solis AG, Herrera - Diaz A, et al :  Human metapneumovirus infections in Mexico: epidemiological and clinical characteristics.   J Med Microbiol   2005; 54:969-974
Cont. ,[object Object],[object Object],[object Object],[object Object],[object Object],Noyola DE, Alpuche - Solis AG, Herrera - Diaz A, et al :  Human metapneumovirus infections in Mexico: epidemiological and clinical characteristics.   J Med Microbiol   2005; 54:969-974
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Clinical Manifestations at Various Ages Takao S, Shimozono H, Kashiwa H, et al :  Clinical study of pediatric cases of acute respiratory diseases associated with human metapneumovirus in Japan.   Jpn J Infect Dis   2003; 56:127-129.
Cont. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Takao S, Shimozono H, Kashiwa H, et al :  Clinical study of pediatric cases of acute respiratory diseases associated with human metapneumovirus in Japan.   Jpn J Infect Dis   2003; 56:127-129.
Diagnosis ,[object Object],[object Object],[object Object],[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],(1)Hamelin ME, Prince GA, Boivin G :  Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection.   Antimicrob Agents Chemother   2006; 50:774-777.
Prevention ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]

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Human metapneumovirus

  • 1. Human Metapneumovirus Prof. Dr. Saad S Al Ani Senior Pediatric Consultant Head of Pediatric Department Khorfakkan Hospital Sharjah ,UAE [email_address]
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  • 8. Bar in the image represents 10 nm. Glycoprotein spikes are visible in viral membrane and extruded nucleocapsid is visible below Human Metapneumovirus
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