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BY DR. TARIQ MASOOD
Pericardial effusion
Constrictive pericarditis.
Pericardial cyst
Hematomas
Neoplasm
Congenital absence of pericardium
Pericardial effusion
Causes;
Myocardial infarction,most common
Collagen vascular disease,especially Lupus
Trauma,Surgical or accidental
Metastatic disease
Tuberculosis, uncommon except in AIDS
Viral infection,Coxsackie A and B virus
Uremia,18% in acute uremia
Plain x ray
Suggestive but not usually diagnostic
"Water bottle configuration" (major DDX is
cardiomegaly)
Loss of retrosternal clear space
"Fat-pad sign“(produced by separation of retrosternal
from epicardial fat line >2 mm)
 Uncommon but specific

Rapidly enlarging cardiac silhouette with normal

pulmonary vascularity
Pericardial effusion on both
frontal chest radiograph and
axial CT. Red arrow points to
fat outside of
pericardium. Green
arrow points to pericardial
space which is 8 mm in this
patient (<4 mm is normal.)
The yellow arrow points to
fat outside of heart and
the blue arrow to the
myocardium.
.
CT
May detect small effusions (50cc)

Fluid-filled space surrounding the myocardium
Early effusions accumulate posteriorly first.
Echocardiogram
Study of choice
Echo-free fluid between the visceral and parietal
pericardium
Early effusions accumulate posteriorly first
> 1cm is usually defined as a “large” effusion
Pericarditis
Acute
Chronic
Recurrent
Constrictive
Acute pericarditis;
Acute pericarditis is dry, fibrinous or effusive,
independent from its etiology.
Chronic pericarditis
Chronic ( 3 months) pericarditis includes effusive

(inflammatory or hydropericardium in heart failure),
adhesive, and constrictive forms.
curable causes are tuberculosis, toxoplasmosis,
myxedema, autoimmune, and systemic diseases.
Constrictive pericarditis
Constrictive pericarditis is a rare but severely disabling

consequence of the chronic inflammation of the pericardium,
leading to an impaired filling of the ventricles and reduced
ventricular function.
Increased pericardial thickness is considered an essential
diagnostic feature of constrictive pericarditis.
Tuberculosis, mediastinal irradiation, and previous cardiac
surgical procedures are frequent causes of the disease
NCCT thorax showing the
thickened pericardium
Chest CT of a patient with clinical
constrictive pericarditis and with
no calcification on chest
radiograph. Areas of pericardial
calcification are evident
(horizontal arrows), but in other
areas (anterior face, vertical arrow)
the pericardium had a normal
appearance.
Axial and coronal black-blood
images of a patient with
constrictive pericarditis after
CABG. Arrows point to the
thickened pericardium.
Pericardial Cyst
Congenital pericardial cysts are uncommon;
 they may be unilocular or multilocular, with the

diameter from 1–5 cm.
 Inflammatory cysts comprise pseudocysts as well as
encapsulated and loculated pericardial effusions,
caused by rheumatic pericarditis, bacterial infection,
particularly tuberculosis, trauma and cardiac surgery.
 Echinococcal cysts usually originate from ruptured

hydatid cysts in the liver and lungs. cysts are detected
incidentally on chest x ray as an oval, homogeneous
radiodense lesion, usually at the right cardiophrenic
angle.
 Echocardiography is useful, but additional imaging by
computed tomography (density readings) or magnetic
resonance is often needed.
Axial CT of the chest reveals a
well-defined cystic structure
measuring approximately 3.5 cm in
diameter located in the right
cardiophrenic angle, abutting the
right heart border. This is most
likely a pericardial cyst
Modified 4-chamber view
showing the pericardial cyst
(★) without compression of
the left ventricle

Pericardial Neoplasm
Differential Diagnosis of Pericardial Masses
A high-density mass was
noted (arrows) adjacent to the
right cardiac border,
compromising and displacing
the heart toward the left. A
biopsy was performed, and it
was shown to be a pericardial
mesothelioma
Pericardial
Teratoma
Mixeddensity mass with
caicification on the right side
of middle mediastinum
Pericardial Metastasis
Metastatic pericardial disease commonly presents as

hemorrhagic effusion. Tumor nodules may enhance after
intravenous contrast administration.
Most frequent CT features of pericardial metastases
include, in order of decreasing frequency:
pericardial effusion
prepericardial lymph nodes
pericardial thickening and enhancement
nodules
Squamous cell carcinoma
with pericardial
metastasis.

Computed tomography of the
chest performed after the
administration of contrast
material revealed multiple
pericardial masses with
central necrosis compatible
with metastatic disease.
Congenital absence of pericardium
Congenital defects of the pericardium comprise

partial left (70%), right (17%) or total bilateral (rare)
pericardial absence. Additional congenital
abnormalities occur in 30% of patients.
 Most patients with a total pericardial absence are
asymptomatic.
Homolateral cardiac displacement and augmented

heart mobility impose an increased risk for traumatic
aortic dissection.
 Partial left side defects can be complicated by
herniation and strangulation of the heart through the
defect (chest pain, shortness of breath, syncope or
sudden death).
Axial T1 MRI of the heart
revealing the partial defect of
the left pericardium.
On magnetic resonance imaging, T2weighted gradient-echo (*) axial ,
and coronal views showed left
pterolateral rotation and
displacement of the heart, with the
apex located in a posterior position.
Thanks

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Pericardial deseases

  • 1. BY DR. TARIQ MASOOD
  • 2. Pericardial effusion Constrictive pericarditis. Pericardial cyst Hematomas Neoplasm Congenital absence of pericardium
  • 3.
  • 4.
  • 5. Pericardial effusion Causes; Myocardial infarction,most common Collagen vascular disease,especially Lupus Trauma,Surgical or accidental Metastatic disease Tuberculosis, uncommon except in AIDS Viral infection,Coxsackie A and B virus Uremia,18% in acute uremia
  • 6. Plain x ray Suggestive but not usually diagnostic "Water bottle configuration" (major DDX is cardiomegaly) Loss of retrosternal clear space "Fat-pad sign“(produced by separation of retrosternal from epicardial fat line >2 mm)  Uncommon but specific Rapidly enlarging cardiac silhouette with normal pulmonary vascularity
  • 7. Pericardial effusion on both frontal chest radiograph and axial CT. Red arrow points to fat outside of pericardium. Green arrow points to pericardial space which is 8 mm in this patient (<4 mm is normal.) The yellow arrow points to fat outside of heart and the blue arrow to the myocardium.
  • 9.
  • 10. CT May detect small effusions (50cc) Fluid-filled space surrounding the myocardium Early effusions accumulate posteriorly first.
  • 11.
  • 12.
  • 13.
  • 14. Echocardiogram Study of choice Echo-free fluid between the visceral and parietal pericardium Early effusions accumulate posteriorly first > 1cm is usually defined as a “large” effusion
  • 15.
  • 17. Acute pericarditis; Acute pericarditis is dry, fibrinous or effusive, independent from its etiology.
  • 18. Chronic pericarditis Chronic ( 3 months) pericarditis includes effusive (inflammatory or hydropericardium in heart failure), adhesive, and constrictive forms. curable causes are tuberculosis, toxoplasmosis, myxedema, autoimmune, and systemic diseases.
  • 19. Constrictive pericarditis Constrictive pericarditis is a rare but severely disabling consequence of the chronic inflammation of the pericardium, leading to an impaired filling of the ventricles and reduced ventricular function. Increased pericardial thickness is considered an essential diagnostic feature of constrictive pericarditis. Tuberculosis, mediastinal irradiation, and previous cardiac surgical procedures are frequent causes of the disease
  • 20.
  • 21.
  • 22. NCCT thorax showing the thickened pericardium
  • 23. Chest CT of a patient with clinical constrictive pericarditis and with no calcification on chest radiograph. Areas of pericardial calcification are evident (horizontal arrows), but in other areas (anterior face, vertical arrow) the pericardium had a normal appearance.
  • 24.
  • 25.
  • 26.
  • 27. Axial and coronal black-blood images of a patient with constrictive pericarditis after CABG. Arrows point to the thickened pericardium.
  • 28. Pericardial Cyst Congenital pericardial cysts are uncommon;  they may be unilocular or multilocular, with the diameter from 1–5 cm.  Inflammatory cysts comprise pseudocysts as well as encapsulated and loculated pericardial effusions, caused by rheumatic pericarditis, bacterial infection, particularly tuberculosis, trauma and cardiac surgery.
  • 29.  Echinococcal cysts usually originate from ruptured hydatid cysts in the liver and lungs. cysts are detected incidentally on chest x ray as an oval, homogeneous radiodense lesion, usually at the right cardiophrenic angle.  Echocardiography is useful, but additional imaging by computed tomography (density readings) or magnetic resonance is often needed.
  • 30.
  • 31.
  • 32. Axial CT of the chest reveals a well-defined cystic structure measuring approximately 3.5 cm in diameter located in the right cardiophrenic angle, abutting the right heart border. This is most likely a pericardial cyst
  • 33. Modified 4-chamber view showing the pericardial cyst (★) without compression of the left ventricle
  • 34.
  • 35.
  • 36.
  • 38. Differential Diagnosis of Pericardial Masses
  • 39. A high-density mass was noted (arrows) adjacent to the right cardiac border, compromising and displacing the heart toward the left. A biopsy was performed, and it was shown to be a pericardial mesothelioma
  • 40. Pericardial Teratoma Mixeddensity mass with caicification on the right side of middle mediastinum
  • 41. Pericardial Metastasis Metastatic pericardial disease commonly presents as hemorrhagic effusion. Tumor nodules may enhance after intravenous contrast administration. Most frequent CT features of pericardial metastases include, in order of decreasing frequency: pericardial effusion prepericardial lymph nodes pericardial thickening and enhancement nodules
  • 42. Squamous cell carcinoma with pericardial metastasis. Computed tomography of the chest performed after the administration of contrast material revealed multiple pericardial masses with central necrosis compatible with metastatic disease.
  • 43. Congenital absence of pericardium Congenital defects of the pericardium comprise partial left (70%), right (17%) or total bilateral (rare) pericardial absence. Additional congenital abnormalities occur in 30% of patients.  Most patients with a total pericardial absence are asymptomatic.
  • 44. Homolateral cardiac displacement and augmented heart mobility impose an increased risk for traumatic aortic dissection.  Partial left side defects can be complicated by herniation and strangulation of the heart through the defect (chest pain, shortness of breath, syncope or sudden death).
  • 45. Axial T1 MRI of the heart revealing the partial defect of the left pericardium.
  • 46. On magnetic resonance imaging, T2weighted gradient-echo (*) axial , and coronal views showed left pterolateral rotation and displacement of the heart, with the apex located in a posterior position.