2. Meninges
Membranes that enclose the brain
and spinal cord
Dura Mater- outer layer
Arachnoid = middle layer
Pia mater = innermost layer
Subarachnoid space = wide
space between arachnoid and
pia mater
3. Subarachnoid space
Wide space between arachnoid and pia mater
Filled with CSF
Bathes brain & spinal cord with nutrients
Cushions against shocks and blows
Where contrast is injected for myelograms
4. CSF Information
Total adult CSF volume is 150 ml
50% intracranial
50% spinal
Adult opening pressure is normally 7-15 cm
fluid
>18 abnormal
Young adults slightly higher <18-20
5. Spinal Cord Diameter
AP diameter is 7mm through C7
C7 to conus medullaris is 6mm
At conus it is 7mm
Cord size is considered abnormal if it is over
8mm or under 6mm
6. Myelography
radiologic examination of the CNS structures situated
in the vertebral canal
Requires contrast introduction into the subarachnoid
space by spinal puncture
Puncture made at L2-L3 or L3-L4 space
May also be introduced into cisterna magna at C1 and
occipital bone
7. Myelography
Contrast is generally
water-soluble,
nonionic, iodinated
medium
OMNIPAQUE
ISOVUE
8. Contrast Precautions
Verify it is the correct contrast
Non-ionic iodinated contrast
Omnipaque or Isovue
Correct concentration
180 and 300 common
Check expiration date
Keep contrast vial in room until procedure is
complete
12. Room should be prepared by RT
before patient arrival
Table and equipment cleaned
Footboard and shoulder
supports attached
Radiographic equipment
checked
Image intensifier locked to
prevent accidental contact
with sterile field or spinal
needle
Tray setup
FOOT
BOARD
SHOULDER
PADS
Hand grips
14. Additional items
Blankets
Sterile towels
Sodium bicarbonate (if not in tray)
Non-ionic iodinated contrast media
Sterile gloves for DR
Shields for PT, DR, anyone else in room
Varying sizes of spinal needles and needles
Extra syringes and tubing
Cleaning liquid
15. Syringes and Spinal Needles
Syringes
Spinal
Needles
(covered)
More Spinal Needles (uncovered)
16. PRE- Procedure :Myelography
Premedication rarely needed
Patient should be well hydrated
Check orders, obtain history, labs results (if necessary),
and previous exams
Informed consent:
Risks, benefits alternatives
Procedural details, including table movement and
sensations should be explained, and get pt into a gown
17. Contraindications and Considerations
PT < 15.0 seconds
Preferable to reschedule exam if below 15
Platelets >100,000
If below 50,000 a platelet transfusion may be indicated
before procedure
Heparin stopped 4 hours before
Can be restarted 2 hrs after procedure
Usually given as IP
Coumadin stopped 3-4 days before
Usually OP
Labs usually indicated
18. Radiation Safety
Have shields for PT’s, DR
Question LMP and the possibility of being pregnant
Use cardinal rules
Time
Distance
Shielding
ALARA
Use pulse if possible
Save the last image on screen when possible
19. Prone &
Lateral Flexion
Prone
Pillow under abdomen
for flexion of spine
Lateral flexion
Widens interspace for
easier introduction of
needle
21. Myelography
Local anesthesia given at puncture
site
Lidocaine and sodium bicarbonate
Spinal needle inserted (pressure
obtained)
CSF usually withdrawn and sent to
laboratory
Contrast injected and needle
removed
9-12 ml
Table angle and gravity used to
move contrast under fluoroscopy
Spot images taken as needed
22. Spot Films
Central ray vertical or horizontal using CR or film
screen cassettes
Images are taken at
Site of blockage
Level of distortion
If conus medullaris is area of concern:
Lay pt supine
Central ray at T12- L1
Use 10x12 cassette and collimate tightly
24. Myelography
If contrast is moved into cervical area, head is
positioned in acute extension to prevent
contrast from entering ventricular system
Acute extension compresses cisterna magna and
is the only position that will prevent contrast from
entering ventricles
25. Myelography
Usually performed as outpatient basis
Common for CT myelography (CTM) to be used with
conventional Myelogram
MRI often used instead
Myelography and CTM still used for patients with
contraindications for MRI
Pacemakers and metal fusion rods
26. Post procedure: Myelography
Monitoring required
Head and shoulders elevated 30 to 45 degrees
Bed rest for several hours
Fluid encouraged
Puncture site checked before release
27. Possible Complications from
Myelography
Vomiting
Vertigo
Neck Pain
Spinal Headache
Due to loss of CSF
during puncture
Increased severity
upright
Decreased pain when
recumbent.
29. Treatment for Spinal Headache
Initial treatment
NSAIDS
Horizontal position
Forced fluids
Caffeine
Persistent headache
If a fever occurs,
May be indicative of
meningitis
Beyond 48 hrs w/o
fever (24 hrs if severe)
Blood patch
30. Blood Patch
Sterily injecting a
small amount of
patient’s blood into the
epidural space
Clot will occur over
hole
Usually will stop
headache immediately
1st patch is 70%
effective
2nd patch is 95%
effective
33. CTM
Performed after intrathecal injection
Can be performed at any level of vertebral column
Multiple slices taken (1.5 – 3mm)
Gantry is tilted
Windowing allows for density and contrast changes
Can obtain images with small amounts of contrast
Can be done 4 hours after initial injection
35. MRI of Spinal Cord and CSF flow
Non-invasive
Provides anatomic detail of brain, spinal cord,
intravertebral disc spaces, and CSF within
subarachnoid space
Does not require intrathecal injection
Does not have bone artifacts
37. Preference of MRI
Spinal cord
Allows direct visualization of spinal cord, nerve
roots, and surrounding CSF
Can be done in various planes
Aid in diagnosis and treatment of neurodisorders
38. Usefulness of MRI
Assessing
demyelinating disease
Such as MS
Spinal cord
compression
Postradiation therapy
changes of spinal cord
tumors
Herniated disks
Congenital
abnormalities of
vertebral column
Metastatic disease
Paraspinal masses
39. Diskography and Nucleography
Radiologic exam of individual intervertebral
disks
Small amount of water soluble iodinated contrast
injected into center of disk double needle entry
Pt’s given local anesthetic
So pt is alert and communicate with DR about pain
when needle and contrast are inserted
Used to investigate disk lesions
Ruptured nucleus pulpous
Has been largely replaced by CTM and MRI
Has protective membranes that enclose the brain and spinal cord
Dura Mater- outer most layer
Tough and fibrous
Arachnoid = middle layer
Has appearance of cobwebs
Pia mater = innermost layer
highly vascular and closely adhered to cortex and spinal cord
Subarachnoid space = wide space between arachnoid and pia mater
Filled with CSF
Bathes brain & spinal cord with nutrients
Cushions against shocks and blows
These pathologies are demonstrated radiographically as a deformity in the subarachnoid space or an obstruction of the passage of the contrast within the subarachnoid space.
It is also useful in identifying a stenosis or narrowing of the subarachnoid space by watching the dynamic flow patterns of the CSF.
Since the Prothrombin time (PT) evaluates the ability of blood to clot properly, it can be used to help diagnose bleeding. When used in this instance, it is often used in conjunction with the PTT to evaluate the function of all coagulation factors. Occasionally, the test may be used to screen patients for any previously undetected bleeding problems prior to surgical procedures.
In an adult, a normal count is about 150,000 to 450,000 platelets per microliter of blood. If platelet levels fall below 20,000 per microliter, spontaneous bleeding may occur and is considered a life-threatening risk. Patients who have a bone marrow disease, such as leukemia or another cancer in the bone marrow, often experience excessive bleeding due to a significantly decreased number of platelets (thrombocytopenia). As the number of cancer cells increases in the bone marrow, normal bone marrow cells are crowded out, resulting in fewer platelet-producing cells.
Low number of platelets may be seen in some patients with long-term bleeding problems (e.g., chronic bleeding stomach ulcers), thus reducing the supply of platelets. Decreased platelet counts may also be seen in patients with Gram-negative sepsis.
Individuals with an autoimmune disorder (such as lupus or idiopathic thrombocytopenia purpura (ITP), where the body’s immune system creates antibodies that attack its own organs) can cause the destruction of platelets
Heparin is a medication that is used in hospitals across the world to prevent blood clot formation. Heparin can be given either directly into the bloodstream, or as an injection under the skin. No oral form of heparin is available. To prevent the formation of dangerous blood clots in people who must stay in bed for prolonged periods of time. This can be accomplished with a low daily dose of this medication which is typically given under the skin, which is known to prevent the formation of deep venous thromboses, or DVTs in the deep veins of the legs, thighs, and pelvis. Such blood clots are known as DVTs for short, and are well known to cause strokes and pulmonary embolisms, (PEs) which can be lethal (see below).
To treat pulmonary embolisms: Pulmonary embolisms are blood clots that migrate into the lungs from the heart, or from the deep venous system of the body. Once in the lungs, pulmonary embolisms can block blood flow to large portions of the lung and prevent oxygen-poor, venous blood from being repleted with oxygen. As stated previously, PEs can be lethal.
To prevent the enlargement of high risk blood clots found inside the heart, and other parts of the body, as they can cause pulmonary embolisms or strokes.
To prevent the formation of blood clots during heart surgery, or during surgery of the large arteries.
Coumadin (warfarin) is an anticoagulant (blood thinner). Coumadin reduces the formation of blood clots by blocking the formation of certain clotting factors.
Coumadin is used to prevent heart attacks, strokes, and blood clots in veins and arteries.
Typical spinal headaches can be differentiated from migraines and other forms of headaches by the change in pain severity with positioning changes. If the patient has increased pain when upright and decreased pain when recumbent, this is a good indication it may be a spinal headache.
It can last up to one week.
Very common for CTM to be done post- conventional Myelogram.
Gantry is tilted so that images are taken parallel to the plane of the vertebral disks of interest.
CTM demonstrates size, shape and positioning of the spinal cord and nerve roots.
It is extremely useful in determining the extent of dural tears resulting from extravasation of the CSF.
Provides excellent anatomic detail.
Allows visualization of the areas of CNS normally obscured by bone
Shows exact demonstration between soft tissue and bone structures
Can be performed in a variety of planes (sagittal, axial and coronal) after acquisition.