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MYELOGRAPHY
Meninges 
 Membranes that enclose the brain 
and spinal cord 
 Dura Mater- outer layer 
 Arachnoid = middle layer 
 Pia mater = innermost layer 
 Subarachnoid space = wide 
space between arachnoid and 
pia mater
Subarachnoid space 
 Wide space between arachnoid and pia mater 
 Filled with CSF 
 Bathes brain & spinal cord with nutrients 
 Cushions against shocks and blows 
 Where contrast is injected for myelograms
CSF Information 
 Total adult CSF volume is 150 ml 
 50% intracranial 
 50% spinal 
 Adult opening pressure is normally 7-15 cm 
fluid 
 >18 abnormal 
 Young adults slightly higher <18-20
Spinal Cord Diameter 
 AP diameter is 7mm through C7 
 C7 to conus medullaris is 6mm 
 At conus it is 7mm 
 Cord size is considered abnormal if it is over 
8mm or under 6mm
Myelography 
 radiologic examination of the CNS structures situated 
in the vertebral canal 
 Requires contrast introduction into the subarachnoid 
space by spinal puncture 
 Puncture made at L2-L3 or L3-L4 space 
 May also be introduced into cisterna magna at C1 and 
occipital bone
Myelography 
 Contrast is generally 
water-soluble, 
nonionic, iodinated 
medium 
OMNIPAQUE 
ISOVUE
Contrast Precautions 
 Verify it is the correct contrast 
 Non-ionic iodinated contrast 
 Omnipaque or Isovue 
 Correct concentration 
 180 and 300 common 
 Check expiration date 
 Keep contrast vial in room until procedure is 
complete
Puncture made at L2-L3 or L3-L4 
space
Spinal needle injection
MYELOGRAM WITH CONTRAST
Room should be prepared by RT 
before patient arrival 
 Table and equipment cleaned 
 Footboard and shoulder 
supports attached 
 Radiographic equipment 
checked 
 Image intensifier locked to 
prevent accidental contact 
with sterile field or spinal 
needle 
 Tray setup 
FOOT 
BOARD 
SHOULDER 
PADS 
Hand grips
MYELOGRAM TRAY
Additional items 
 Blankets 
 Sterile towels 
 Sodium bicarbonate (if not in tray) 
 Non-ionic iodinated contrast media 
 Sterile gloves for DR 
 Shields for PT, DR, anyone else in room 
 Varying sizes of spinal needles and needles 
 Extra syringes and tubing 
 Cleaning liquid
Syringes and Spinal Needles 
Syringes 
Spinal 
Needles 
(covered) 
More Spinal Needles (uncovered)
PRE- Procedure :Myelography 
 Premedication rarely needed 
 Patient should be well hydrated 
 Check orders, obtain history, labs results (if necessary), 
and previous exams 
 Informed consent: 
 Risks, benefits alternatives 
 Procedural details, including table movement and 
sensations should be explained, and get pt into a gown
Contraindications and Considerations 
 PT < 15.0 seconds 
 Preferable to reschedule exam if below 15 
 Platelets >100,000 
 If below 50,000 a platelet transfusion may be indicated 
before procedure 
 Heparin stopped 4 hours before 
 Can be restarted 2 hrs after procedure 
 Usually given as IP 
 Coumadin stopped 3-4 days before 
 Usually OP 
 Labs usually indicated
Radiation Safety 
 Have shields for PT’s, DR 
 Question LMP and the possibility of being pregnant 
 Use cardinal rules 
 Time 
 Distance 
 Shielding 
 ALARA 
 Use pulse if possible 
 Save the last image on screen when possible
Prone & 
Lateral Flexion 
 Prone 
 Pillow under abdomen 
for flexion of spine 
 Lateral flexion 
 Widens interspace for 
easier introduction of 
needle
Scout Images 
 Cross table lateral 
 With grid 
 Closely collimated
Myelography 
 Local anesthesia given at puncture 
site 
 Lidocaine and sodium bicarbonate 
 Spinal needle inserted (pressure 
obtained) 
 CSF usually withdrawn and sent to 
laboratory 
 Contrast injected and needle 
removed 
 9-12 ml 
 Table angle and gravity used to 
move contrast under fluoroscopy 
 Spot images taken as needed
Spot Films 
 Central ray vertical or horizontal using CR or film 
screen cassettes 
 Images are taken at 
 Site of blockage 
 Level of distortion 
 If conus medullaris is area of concern: 
 Lay pt supine 
 Central ray at T12- L1 
 Use 10x12 cassette and collimate tightly
Myelogram overview
Myelography 
 If contrast is moved into cervical area, head is 
positioned in acute extension to prevent 
contrast from entering ventricular system 
 Acute extension compresses cisterna magna and 
is the only position that will prevent contrast from 
entering ventricles
Myelography 
 Usually performed as outpatient basis 
 Common for CT myelography (CTM) to be used with 
conventional Myelogram 
 MRI often used instead 
 Myelography and CTM still used for patients with 
contraindications for MRI 
 Pacemakers and metal fusion rods
Post procedure: Myelography 
 Monitoring required 
 Head and shoulders elevated 30 to 45 degrees 
 Bed rest for several hours 
 Fluid encouraged 
 Puncture site checked before release
Possible Complications from 
Myelography 
 Vomiting 
 Vertigo 
 Neck Pain 
 Spinal Headache 
 Due to loss of CSF 
during puncture 
 Increased severity 
upright 
 Decreased pain when 
recumbent.
More Severe Complications 
 Nerve root damage 
 Meningitis 
 Epidural abscess 
 Contrast reaction (anaphylactic shock) 
 CSF leak 
 Hemorrhage
Treatment for Spinal Headache 
 Initial treatment 
 NSAIDS 
 Horizontal position 
 Forced fluids 
 Caffeine 
 Persistent headache 
 If a fever occurs, 
 May be indicative of 
meningitis 
 Beyond 48 hrs w/o 
fever (24 hrs if severe) 
 Blood patch
Blood Patch 
 Sterily injecting a 
small amount of 
patient’s blood into the 
epidural space 
 Clot will occur over 
hole 
 Usually will stop 
headache immediately 
 1st patch is 70% 
effective 
 2nd patch is 95% 
effective
Myelogram radiographs
Myelograms Images
CTM 
 Performed after intrathecal injection 
 Can be performed at any level of vertebral column 
 Multiple slices taken (1.5 – 3mm) 
 Gantry is tilted 
 Windowing allows for density and contrast changes 
 Can obtain images with small amounts of contrast 
 Can be done 4 hours after initial injection
CTM
MRI of Spinal Cord and CSF flow 
 Non-invasive 
 Provides anatomic detail of brain, spinal cord, 
intravertebral disc spaces, and CSF within 
subarachnoid space 
 Does not require intrathecal injection 
 Does not have bone artifacts
Myelography Using MRI and 
Conventional methods 
MYELOGRAM
Preference of MRI 
 Spinal cord 
 Allows direct visualization of spinal cord, nerve 
roots, and surrounding CSF 
 Can be done in various planes 
 Aid in diagnosis and treatment of neurodisorders
Usefulness of MRI 
 Assessing 
demyelinating disease 
 Such as MS 
 Spinal cord 
compression 
 Postradiation therapy 
changes of spinal cord 
tumors 
 Herniated disks 
 Congenital 
abnormalities of 
vertebral column 
 Metastatic disease 
 Paraspinal masses
Diskography and Nucleography 
 Radiologic exam of individual intervertebral 
disks 
 Small amount of water soluble iodinated contrast 
injected into center of disk double needle entry 
 Pt’s given local anesthetic 
 So pt is alert and communicate with DR about pain 
when needle and contrast are inserted 
 Used to investigate disk lesions 
 Ruptured nucleus pulpous 
 Has been largely replaced by CTM and MRI
Diskograms
Lumbar Diskograms
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Myelography

  • 2. Meninges  Membranes that enclose the brain and spinal cord  Dura Mater- outer layer  Arachnoid = middle layer  Pia mater = innermost layer  Subarachnoid space = wide space between arachnoid and pia mater
  • 3. Subarachnoid space  Wide space between arachnoid and pia mater  Filled with CSF  Bathes brain & spinal cord with nutrients  Cushions against shocks and blows  Where contrast is injected for myelograms
  • 4. CSF Information  Total adult CSF volume is 150 ml  50% intracranial  50% spinal  Adult opening pressure is normally 7-15 cm fluid  >18 abnormal  Young adults slightly higher <18-20
  • 5. Spinal Cord Diameter  AP diameter is 7mm through C7  C7 to conus medullaris is 6mm  At conus it is 7mm  Cord size is considered abnormal if it is over 8mm or under 6mm
  • 6. Myelography  radiologic examination of the CNS structures situated in the vertebral canal  Requires contrast introduction into the subarachnoid space by spinal puncture  Puncture made at L2-L3 or L3-L4 space  May also be introduced into cisterna magna at C1 and occipital bone
  • 7. Myelography  Contrast is generally water-soluble, nonionic, iodinated medium OMNIPAQUE ISOVUE
  • 8. Contrast Precautions  Verify it is the correct contrast  Non-ionic iodinated contrast  Omnipaque or Isovue  Correct concentration  180 and 300 common  Check expiration date  Keep contrast vial in room until procedure is complete
  • 9. Puncture made at L2-L3 or L3-L4 space
  • 12. Room should be prepared by RT before patient arrival  Table and equipment cleaned  Footboard and shoulder supports attached  Radiographic equipment checked  Image intensifier locked to prevent accidental contact with sterile field or spinal needle  Tray setup FOOT BOARD SHOULDER PADS Hand grips
  • 14. Additional items  Blankets  Sterile towels  Sodium bicarbonate (if not in tray)  Non-ionic iodinated contrast media  Sterile gloves for DR  Shields for PT, DR, anyone else in room  Varying sizes of spinal needles and needles  Extra syringes and tubing  Cleaning liquid
  • 15. Syringes and Spinal Needles Syringes Spinal Needles (covered) More Spinal Needles (uncovered)
  • 16. PRE- Procedure :Myelography  Premedication rarely needed  Patient should be well hydrated  Check orders, obtain history, labs results (if necessary), and previous exams  Informed consent:  Risks, benefits alternatives  Procedural details, including table movement and sensations should be explained, and get pt into a gown
  • 17. Contraindications and Considerations  PT < 15.0 seconds  Preferable to reschedule exam if below 15  Platelets >100,000  If below 50,000 a platelet transfusion may be indicated before procedure  Heparin stopped 4 hours before  Can be restarted 2 hrs after procedure  Usually given as IP  Coumadin stopped 3-4 days before  Usually OP  Labs usually indicated
  • 18. Radiation Safety  Have shields for PT’s, DR  Question LMP and the possibility of being pregnant  Use cardinal rules  Time  Distance  Shielding  ALARA  Use pulse if possible  Save the last image on screen when possible
  • 19. Prone & Lateral Flexion  Prone  Pillow under abdomen for flexion of spine  Lateral flexion  Widens interspace for easier introduction of needle
  • 20. Scout Images  Cross table lateral  With grid  Closely collimated
  • 21. Myelography  Local anesthesia given at puncture site  Lidocaine and sodium bicarbonate  Spinal needle inserted (pressure obtained)  CSF usually withdrawn and sent to laboratory  Contrast injected and needle removed  9-12 ml  Table angle and gravity used to move contrast under fluoroscopy  Spot images taken as needed
  • 22. Spot Films  Central ray vertical or horizontal using CR or film screen cassettes  Images are taken at  Site of blockage  Level of distortion  If conus medullaris is area of concern:  Lay pt supine  Central ray at T12- L1  Use 10x12 cassette and collimate tightly
  • 24. Myelography  If contrast is moved into cervical area, head is positioned in acute extension to prevent contrast from entering ventricular system  Acute extension compresses cisterna magna and is the only position that will prevent contrast from entering ventricles
  • 25. Myelography  Usually performed as outpatient basis  Common for CT myelography (CTM) to be used with conventional Myelogram  MRI often used instead  Myelography and CTM still used for patients with contraindications for MRI  Pacemakers and metal fusion rods
  • 26. Post procedure: Myelography  Monitoring required  Head and shoulders elevated 30 to 45 degrees  Bed rest for several hours  Fluid encouraged  Puncture site checked before release
  • 27. Possible Complications from Myelography  Vomiting  Vertigo  Neck Pain  Spinal Headache  Due to loss of CSF during puncture  Increased severity upright  Decreased pain when recumbent.
  • 28. More Severe Complications  Nerve root damage  Meningitis  Epidural abscess  Contrast reaction (anaphylactic shock)  CSF leak  Hemorrhage
  • 29. Treatment for Spinal Headache  Initial treatment  NSAIDS  Horizontal position  Forced fluids  Caffeine  Persistent headache  If a fever occurs,  May be indicative of meningitis  Beyond 48 hrs w/o fever (24 hrs if severe)  Blood patch
  • 30. Blood Patch  Sterily injecting a small amount of patient’s blood into the epidural space  Clot will occur over hole  Usually will stop headache immediately  1st patch is 70% effective  2nd patch is 95% effective
  • 33. CTM  Performed after intrathecal injection  Can be performed at any level of vertebral column  Multiple slices taken (1.5 – 3mm)  Gantry is tilted  Windowing allows for density and contrast changes  Can obtain images with small amounts of contrast  Can be done 4 hours after initial injection
  • 34. CTM
  • 35. MRI of Spinal Cord and CSF flow  Non-invasive  Provides anatomic detail of brain, spinal cord, intravertebral disc spaces, and CSF within subarachnoid space  Does not require intrathecal injection  Does not have bone artifacts
  • 36. Myelography Using MRI and Conventional methods MYELOGRAM
  • 37. Preference of MRI  Spinal cord  Allows direct visualization of spinal cord, nerve roots, and surrounding CSF  Can be done in various planes  Aid in diagnosis and treatment of neurodisorders
  • 38. Usefulness of MRI  Assessing demyelinating disease  Such as MS  Spinal cord compression  Postradiation therapy changes of spinal cord tumors  Herniated disks  Congenital abnormalities of vertebral column  Metastatic disease  Paraspinal masses
  • 39. Diskography and Nucleography  Radiologic exam of individual intervertebral disks  Small amount of water soluble iodinated contrast injected into center of disk double needle entry  Pt’s given local anesthetic  So pt is alert and communicate with DR about pain when needle and contrast are inserted  Used to investigate disk lesions  Ruptured nucleus pulpous  Has been largely replaced by CTM and MRI

Hinweis der Redaktion

  1. Has protective membranes that enclose the brain and spinal cord Dura Mater- outer most layer Tough and fibrous Arachnoid = middle layer Has appearance of cobwebs Pia mater = innermost layer highly vascular and closely adhered to cortex and spinal cord Subarachnoid space = wide space between arachnoid and pia mater Filled with CSF Bathes brain &amp; spinal cord with nutrients Cushions against shocks and blows
  2. These pathologies are demonstrated radiographically as a deformity in the subarachnoid space or an obstruction of the passage of the contrast within the subarachnoid space. It is also useful in identifying a stenosis or narrowing of the subarachnoid space by watching the dynamic flow patterns of the CSF.
  3. Since the Prothrombin time (PT) evaluates the ability of blood to clot properly, it can be used to help diagnose bleeding. When used in this instance, it is often used in conjunction with the PTT to evaluate the function of all coagulation factors. Occasionally, the test may be used to screen patients for any previously undetected bleeding problems prior to surgical procedures. In an adult, a normal count is about 150,000 to 450,000 platelets per microliter of blood. If platelet levels fall below 20,000 per microliter, spontaneous bleeding may occur and is considered a life-threatening risk. Patients who have a bone marrow disease, such as leukemia or another cancer in the bone marrow, often experience excessive bleeding due to a significantly decreased number of platelets (thrombocytopenia). As the number of cancer cells increases in the bone marrow, normal bone marrow cells are crowded out, resulting in fewer platelet-producing cells. Low number of platelets may be seen in some patients with long-term bleeding problems (e.g., chronic bleeding stomach ulcers), thus reducing the supply of platelets. Decreased platelet counts may also be seen in patients with Gram-negative sepsis. Individuals with an autoimmune disorder (such as lupus or idiopathic thrombocytopenia purpura (ITP), where the body’s immune system creates antibodies that attack its own organs) can cause the destruction of platelets Heparin is a medication that is used in hospitals across the world to prevent blood clot formation. Heparin can be given either directly into the bloodstream, or as an injection under the skin. No oral form of heparin is available. To prevent the formation of dangerous blood clots in people who must stay in bed for prolonged periods of time. This can be accomplished with a low daily dose of this medication which is typically given under the skin, which is known to prevent the formation of deep venous thromboses, or DVTs in the deep veins of the legs, thighs, and pelvis. Such blood clots are known as DVTs for short, and are well known to cause strokes and pulmonary embolisms, (PEs) which can be lethal (see below). To treat pulmonary embolisms: Pulmonary embolisms are blood clots that migrate into the lungs from the heart, or from the deep venous system of the body. Once in the lungs, pulmonary embolisms can block blood flow to large portions of the lung and prevent oxygen-poor, venous blood from being repleted with oxygen. As stated previously, PEs can be lethal. To prevent the enlargement of high risk blood clots found inside the heart, and other parts of the body, as they can cause pulmonary embolisms or strokes. To prevent the formation of blood clots during heart surgery, or during surgery of the large arteries. Coumadin (warfarin) is an anticoagulant (blood thinner). Coumadin reduces the formation of blood clots by blocking the formation of certain clotting factors. Coumadin is used to prevent heart attacks, strokes, and blood clots in veins and arteries.
  4. Typical spinal headaches can be differentiated from migraines and other forms of headaches by the change in pain severity with positioning changes. If the patient has increased pain when upright and decreased pain when recumbent, this is a good indication it may be a spinal headache.
  5. It can last up to one week.
  6. Very common for CTM to be done post- conventional Myelogram. Gantry is tilted so that images are taken parallel to the plane of the vertebral disks of interest. CTM demonstrates size, shape and positioning of the spinal cord and nerve roots. It is extremely useful in determining the extent of dural tears resulting from extravasation of the CSF.
  7. Provides excellent anatomic detail. Allows visualization of the areas of CNS normally obscured by bone Shows exact demonstration between soft tissue and bone structures
  8. Can be performed in a variety of planes (sagittal, axial and coronal) after acquisition.