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Siti Nurul Afiqah binti Johari (10-6-95)
Clinical picture
Investigations
i. Laboratory:
• ABG: might be normal, type 1 RF, severe hypoxemia,
mild hypocapnea
• D-dimer
ii. ECG: Sinus tachycardia, Rt BBB,
ST-T abnormalities
ii. Radiological:
• Chest X-ray
• CTPA
• V/Q lung scan
What to consider in geriatrics?
• Sensitivity to the anticoagulant effect of a given
dose increases with age
• Polypharmacy (include self med) increases risk of
drug interactions which alter oral anticoagulant
effect or which increase the risk of bleeding
• Increased prevalence of concurrent or
intercurrent illness
• Decreased compliance or decreased access to
monitoring
Prophylaxis
• Patients who undergone
surgery, 4-6 weeks of
LMWH or UFH
• Graduated compressive
stockings and pneumatic
compression devices
Treatment
• LMWH prevents clot formation
and extension given SC 1/2x a
day
• Long term anticoagulation
after discharge is warfarin
• Thrombolytic therapy with
massive PE who have
significant pulmonary HTN,
obstruction of multiple
segments of pulmonary
circulation, rt ventricular dysfx
or systemic hypotension
• IVC filter in special
circumstances

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Pulmonary Embolism in Geriatrics

  • 1. Siti Nurul Afiqah binti Johari (10-6-95)
  • 2.
  • 4. Investigations i. Laboratory: • ABG: might be normal, type 1 RF, severe hypoxemia, mild hypocapnea • D-dimer ii. ECG: Sinus tachycardia, Rt BBB, ST-T abnormalities ii. Radiological: • Chest X-ray • CTPA • V/Q lung scan
  • 5. What to consider in geriatrics? • Sensitivity to the anticoagulant effect of a given dose increases with age • Polypharmacy (include self med) increases risk of drug interactions which alter oral anticoagulant effect or which increase the risk of bleeding • Increased prevalence of concurrent or intercurrent illness • Decreased compliance or decreased access to monitoring
  • 6. Prophylaxis • Patients who undergone surgery, 4-6 weeks of LMWH or UFH • Graduated compressive stockings and pneumatic compression devices Treatment • LMWH prevents clot formation and extension given SC 1/2x a day • Long term anticoagulation after discharge is warfarin • Thrombolytic therapy with massive PE who have significant pulmonary HTN, obstruction of multiple segments of pulmonary circulation, rt ventricular dysfx or systemic hypotension • IVC filter in special circumstances